公开(公告)号：US11781035B2

公开(公告)日：2023-10-10

申请号：US16771285

申请日：2018-12-11

Applicant: Innovative Surface Technologies, Inc.

Inventor： Kristin Taton ,  Daniel Guire ,  Nathaniel Olson ,  Eric Guire ,  Patrick Guire

IPC: C08G18/32 ,  C09D175/02 ,  A61B5/00 ,  B05D1/02 ,  B05D1/18 ,  C08G18/50 ,  C08G18/66 ,  C08G18/73 ,  C08G18/75 ,  C09D5/16

CPC classification number: C09D175/02 ,  A61B5/6846 ,  B05D1/02 ,  B05D1/18 ,  C08G18/325 ,  C08G18/3228 ,  C08G18/5024 ,  C08G18/6685 ,  C08G18/73 ,  C08G18/755 ,  C09D5/1662

Abstract: Durable polyurea copolymer coatings can be applied to surfaces that come in contact with fluids, such as biological fluids, thereby passivating the surface. Polyurea copolymer coating compositions comprise a reaction product of (a) a diamine composition that includes a polyethylene glycol diamine, and optionally, a dipiperidyl alkane; and (b) a diisocyanate. Solutions containing polyurea copolymers, coated surfaces and methods are also described.

公开(公告)号：US20230399538A1

公开(公告)日：2023-12-14

申请号：US18237883

申请日：2023-08-24

Applicant: Innovative Surface Technologies, Inc.

Inventor： Kristin Taton ,  Daniel Guire ,  Nathaniel Olson ,  Eric Guire ,  Patrick Guire

IPC: C09D175/02 ,  A61B5/00 ,  B05D1/02 ,  B05D1/18 ,  C08G18/32 ,  C08G18/50 ,  C08G18/66 ,  C08G18/73 ,  C08G18/75 ,  C09D5/16

CPC classification number: C09D175/02 ,  A61B5/6846 ,  B05D1/02 ,  B05D1/18 ,  C08G18/3228 ,  C08G18/325 ,  C08G18/5024 ,  C08G18/6685 ,  C08G18/73 ,  C08G18/755 ,  C09D5/1662

Abstract: Durable polyurea copolymer coatings can be applied to surfaces that come in contact with fluids, such as biological fluids, thereby passivating the surface. Polyurea copolymer coating compositions comprise a reaction product of (a) a diamine composition that includes a polyethylene glycol diamine, and optionally, a dipiperidyl alkane; and (b) a diisocyanate. Solutions containing polyurea copolymers, coated surfaces and methods are also described.

公开(公告)号：US11672884B2

公开(公告)日：2023-06-13

申请号：US16771380

申请日：2018-12-11

Applicant: Innovative Surface Technologies, Inc.

Inventor： Kristin Taton ,  Patrick Guire ,  Charles Leir

IPC: A61L31/10 ,  A61L27/34 ,  C08G18/61 ,  C08G18/64 ,  C08G18/73 ,  C08G18/75 ,  C08G18/77 ,  C09D183/10

CPC classification number: A61L27/34 ,  A61L31/10 ,  C08G18/61 ,  C08G18/6423 ,  C08G18/73 ,  C08G18/757 ,  C08G18/778 ,  C09D183/10 ,  C08G2150/00

Abstract: Silicone polyurea block copolymers are prepared by copolymerizing: (a) a diamine composition that includes a polyethylene glycol diamine, and optionally, a dipiperidyl alkane; (b) a monofunctional silicone isocyanate; and (c) a diisocyanate. Compositions useful as passivating coatings comprising the block copolymer are also provided, and substrates coated with the compositions. Methods of preparing and using the compositions are also described.

公开(公告)号：US09814805B2

公开(公告)日：2017-11-14

申请号：US14786842

申请日：2014-04-25

Applicant: INNOVATIVE SURFACE TECHNOLOGIES, INC.

Inventor： Kristin Taton ,  Lawin Laurie ,  Patrick Guire

IPC: A61L29/08 ,  A61L27/54 ,  A61L31/16 ,  A61L31/10 ,  A61L27/34 ,  A61L29/16 ,  A61L29/10 ,  A61L29/06

CPC classification number: A61L29/085 ,  A61L27/34 ,  A61L27/54 ,  A61L29/06 ,  A61L29/106 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/104 ,  A61L2300/206 ,  A61L2300/602 ,  A61L2300/608 ,  A61L2420/02 ,  A61L2420/08 ,  C08L83/04

Abstract: The present disclosure relates to multilayer coatings that include a hydrophobic encasing layer and allow controlled release of a water soluble drug. The encasing layer encases water soluble, or hydrophilic, drugs with a flexible layer and comes in good intimate contact with the water soluble drug layer. Thus, the encasing layer conforms to the water soluble drug and can control the release of the drug. Advantageously, major cuts or fissures in the coating do not cause the water soluble drug to leak or burst out; rather, the encasing layer continues to provide modulated release of the drug. The present disclosure also includes methods of making the multilayer coatings, methods of using the multilayer coatings, and articles that include the multilayer coatings.

公开(公告)号：US09539371B2

公开(公告)日：2017-01-10

申请号：US14749815

申请日：2015-06-25

Applicant: Innovative Surface Technologies, Inc.

Inventor： Jie Wen ,  Kristin Taton ,  Laurie Lawin ,  William Knopke ,  Eric Guire ,  Patrick Guire

IPC: C09D137/00 ,  A61L31/10 ,  C08F8/30 ,  C08F8/42 ,  C09D131/00 ,  A61L31/02 ,  A61L31/06 ,  A61L31/14 ,  A61L31/16 ,  A61L33/00 ,  B05D3/06

CPC classification number: C08F8/42 ,  A61L29/06 ,  A61L29/085 ,  A61L29/14 ,  A61L29/16 ,  A61L31/022 ,  A61L31/06 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16 ,  A61L33/0005 ,  A61L2300/404 ,  A61L2300/42 ,  A61L2400/10 ,  A61L2420/02 ,  A61L2420/08 ,  B05D3/06 ,  C08F8/28 ,  C08F8/30 ,  C08F267/04 ,  C09D131/00 ,  C09D135/00 ,  Y10T428/31507 ,  Y10T428/31511 ,  Y10T428/31573 ,  Y10T428/31598 ,  Y10T428/31663 ,  Y10T428/31667 ,  Y10T428/31721 ,  Y10T428/3175 ,  Y10T428/31797 ,  Y10T428/31855 ,  Y10T428/31884 ,  Y10T428/31909 ,  Y10T428/31913 ,  Y10T428/31928 ,  C08F222/06

Abstract: The invention describes novel coating agents that include a polymer, one or more latent reactive groups and one or more noncovalent linking groups, the noncovalent linking groups selected to interact with a substrate to which the coating agent is applied.

Abstract translation: 本发明描述了新颖的涂层剂，其包括聚合物，一个或多个潜在反应性基团和一个或多个非共价连接基团，所选择的非共价连接基团与施加涂覆剂的基底相互作用。

公开(公告)号：US20150359944A1

公开(公告)日：2015-12-17

申请号：US14749815

申请日：2015-06-25

Applicant: Innovative Surface Technologies, Inc.

Inventor： Jie Wen ,  Kristin Taton ,  Laurie Lawin ,  William Knopke ,  Eric Guire ,  Patrick Guire

IPC: A61L31/10 ,  A61L31/14 ,  A61L33/00 ,  A61L31/02 ,  A61L31/06 ,  B05D3/06 ,  A61L31/16

CPC classification number: C08F8/42 ,  A61L29/06 ,  A61L29/085 ,  A61L29/14 ,  A61L29/16 ,  A61L31/022 ,  A61L31/06 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16 ,  A61L33/0005 ,  A61L2300/404 ,  A61L2300/42 ,  A61L2400/10 ,  A61L2420/02 ,  A61L2420/08 ,  B05D3/06 ,  C08F8/28 ,  C08F8/30 ,  C08F267/04 ,  C09D131/00 ,  C09D135/00 ,  Y10T428/31507 ,  Y10T428/31511 ,  Y10T428/31573 ,  Y10T428/31598 ,  Y10T428/31663 ,  Y10T428/31667 ,  Y10T428/31721 ,  Y10T428/3175 ,  Y10T428/31797 ,  Y10T428/31855 ,  Y10T428/31884 ,  Y10T428/31909 ,  Y10T428/31913 ,  Y10T428/31928 ,  C08F222/06

Abstract: The invention describes novel coating agents that include a polymer, one or more latent reactive groups and one or more noncovalent linking groups, the noncovalent linking groups selected to interact with a substrate to which the coating agent is applied. The coating agents are useful for providing a coating that can be further functionalized (for example, by

Abstract translation: 本发明描述了新颖的涂层剂，其包括聚合物，一个或多个潜在反应性基团和一个或多个非共价连接基团，所选择的非共价连接基团与施加涂覆剂的基底相互作用。 涂层剂可用于提供可以进一步官能化的涂层（例如，

公开(公告)号：US12269963B2

公开(公告)日：2025-04-08

申请号：US18237883

申请日：2023-08-24

Applicant: Innovative Surface Technologies, Inc.

Inventor： Kristin Taton ,  Daniel Guire ,  Nathaniel Olson ,  Eric Guire ,  Patrick Guire

IPC: C09D175/02 ,  A61B5/00 ,  B05D1/02 ,  B05D1/18 ,  C08G18/32 ,  C08G18/50 ,  C08G18/66 ,  C08G18/73 ,  C08G18/75 ,  C09D5/16

Abstract: Durable polyurea copolymer coatings can be applied to surfaces that come in contact with fluids, such as biological fluids, thereby passivating the surface. Polyurea copolymer coating compositions comprise a reaction product of (a) a diamine composition that includes a polyethylene glycol diamine, and optionally, a dipiperidyl alkane; and (b) a diisocyanate. Solutions containing polyurea copolymers, coated surfaces and methods are also described.

公开(公告)号：US20200377756A1

公开(公告)日：2020-12-03

申请号：US16771285

申请日：2018-12-11

Applicant: Innovative Surface Technologies, Inc.

Inventor： Kristin Taton ,  Daniel Guire ,  Nathaniel Olson ,  Eric Guire ,  Patrick Guire

IPC: C09D175/02 ,  C09D5/16 ,  C08G18/75 ,  C08G18/73 ,  C08G18/66 ,  C08G18/50 ,  C08G18/32 ,  A61B5/00 ,  B05D1/02 ,  B05D1/18

Abstract: Durable polyurea copolymer coatings can be applied to surfaces that come in contact with fluids, such as biological fluids, thereby passivating the surface. Polyurea copolymer coating compositions comprise a reaction product of (a) a diamine composition that includes a polyethylene glycol diamine, and optionally, a dipiperidyl alkane; and (b) a diisocyanate. Solutions containing polyurea copolymers, coated surfaces and methods are also described.

公开(公告)号：US10266620B2

公开(公告)日：2019-04-23

申请号：US15370410

申请日：2016-12-06

Applicant: Innovative Surface Technologies, Inc.

Inventor： Jie Wen ,  Kristin Taton ,  Laurie Lawin ,  William Knopke ,  Eric Guire ,  Patrick Guire

IPC: C09D137/00 ,  C08F8/42 ,  C08F8/30 ,  C09D131/00 ,  A61L31/02 ,  A61L31/06 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16 ,  A61L33/00 ,  B05D3/06 ,  A61L29/06 ,  A61L29/08 ,  A61L29/14 ,  A61L29/16 ,  C08F8/28 ,  C08F267/04 ,  C09D135/00

Abstract: The invention describes novel coating agents that include a polymer, one or more latent reactive groups and one or more noncovalent linking groups, the noncovalent linking groups selected to interact with a substrate to which the coating agent is applied. The coating agents are useful for providing a coating that can be further functionalized (for example, by application of additional coating layers), or for providing desirable properties to a surface.

公开(公告)号：US20140011938A1

公开(公告)日：2014-01-09

申请号：US13952694

申请日：2013-07-29

Applicant: INNOVATIVE SURFACE TECHNOLOGIES, INC.

Inventor： Patrick E. Guire ,  Kristin Taton ,  Jie Wen ,  Laurie R. Lawin

IPC: C09D7/12

CPC classification number: C09D7/63 ,  C08K5/0025 ,  Y10T428/31507 ,  Y10T428/31511 ,  Y10T428/31551 ,  Y10T428/31678 ,  Y10T428/31721 ,  Y10T428/31725 ,  Y10T428/31855 ,  Y10T428/31989 ,  Y10T428/31993

Abstract: The invention describes novel compositions that include a cross linking compound, a polymer and a 1 nm to about a 25 micron sized particle optionally with an oxide layer. In particular, the particle is a silica and one which has been pretreated with a silane.

Abstract translation: 本发明描述了包含交联化合物，聚合物和任选具有氧化物层的1nm至约25微米尺寸的颗粒的新型组合物。 特别地，颗粒是二氧化硅和已经用硅烷预处理的颗粒。