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1.
公开(公告)号:US20210163877A1
公开(公告)日:2021-06-03
申请号:US17175612
申请日:2021-02-13
Applicant: Inscripta, Inc.
Inventor: Phillip Belgrader , Don Masquelier , Andrew Garst , Richard Fox
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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公开(公告)号:US20210108195A1
公开(公告)日:2021-04-15
申请号:US17131582
申请日:2020-12-22
Applicant: Inscripta, Inc.
Inventor: Jorge Bernate , Kevin Ness , Phillip Belgrader , Don Masquelier , Ryan Gill
IPC: C12N15/10 , C40B40/02 , C12M1/26 , C12M1/42 , C12M1/34 , C12M3/00 , C12M1/36 , C12M1/00 , C12N9/22 , C12N15/11 , C12M1/12
Abstract: In an illustrative embodiment, automated multi-module cell editing instruments are provided to automate multiple edits into nucleic acid sequences inside one or more cells.
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3.
公开(公告)号:US20210108171A1
公开(公告)日:2021-04-15
申请号:US17102414
申请日:2020-11-23
Applicant: Inscripta, Inc.
Inventor: Andrew Garst , Richard Fox , Phillip Belgrader , Don Masquelier
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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4.
公开(公告)号:US20210031144A1
公开(公告)日:2021-02-04
申请号:US17073300
申请日:2020-10-17
Applicant: Inscripta, Inc.
Inventor: Phillip Belgrader , Don Masquelier , Matthew Estes , Bruce Chabansky , Andrew Garst , Richard Fox , Jorge Bernate
IPC: B01D63/08
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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公开(公告)号:US10883077B2
公开(公告)日:2021-01-05
申请号:US16836664
申请日:2020-03-31
Applicant: Inscripta, Inc.
Inventor: Phillip Belgrader , Don Masquelier
Abstract: The present disclosure relates to methods for control of cell growth rates where cell growth is measured in situ. The methods are applicable to bacterial cells, mammalian cells, non-mammalian eukaryotic cells, plant cells, yeast cells, fungi, and archea.
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6.
公开(公告)号:US20200347342A1
公开(公告)日:2020-11-05
申请号:US16930269
申请日:2020-07-15
Applicant: Inscripta, Inc.
Inventor: Phillip Belgrader , Don Masquelier , Andrew Garst , Richard Fox
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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公开(公告)号:US20200270601A1
公开(公告)日:2020-08-27
申请号:US16837985
申请日:2020-04-01
Applicant: Inscripta, Inc.
Inventor: Phillip Belgrader , Don Masquelier , Jorge Bernate , Ryan Gill , Kevin Ness
IPC: C12N15/10 , C12M1/26 , C12N9/22 , C12M1/42 , C12M3/00 , C12N15/11 , C12M1/00 , C40B40/02 , C12M1/34 , C12M1/12 , C12M1/36
Abstract: In an illustrative embodiment, automated multi-module cell editing instruments are provided to automate multiple edits into nucleic acid sequences inside one or more cells.
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公开(公告)号:US10738301B1
公开(公告)日:2020-08-11
申请号:US16837985
申请日:2020-04-01
Applicant: Inscripta, Inc.
Inventor: Phillip Belgrader , Don Masquelier , Jorge Bernate , Ryan Gill , Kevin Ness
IPC: C12M3/00 , C12M1/00 , C12N15/10 , C12M1/26 , C12N9/22 , C12M1/42 , C12N15/11 , C40B40/02 , C12M1/34 , C12M1/12 , C12M1/36
Abstract: In an illustrative embodiment, automated multi-module cell editing instruments are provided to automate multiple edits into nucleic acid sequences inside one or more cells.
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9.
公开(公告)号:US20200248131A1
公开(公告)日:2020-08-06
申请号:US16820324
申请日:2020-03-16
Applicant: Inscripta, Inc.
Inventor: Andrew Garst , Richard Fox , Phillip Belgrader , Don Masquelier
Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
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公开(公告)号:US20200224146A1
公开(公告)日:2020-07-16
申请号:US16836664
申请日:2020-03-31
Applicant: Inscripta, Inc.
Inventor: Phillip Belgrader , Don Masquelier
Abstract: The present disclosure relates to methods for control of cell growth rates where cell growth is measured in situ. The methods are applicable to bacterial cells, mammalian cells, non-mammalian eukaryotic cells, plant cells, yeast cells, fungi, and archea.
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