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公开(公告)号：US10722510B2
公开(公告)日：2020-07-28
申请号：US15238909
申请日：2016-08-17
Applicant: Insys Development Company, Inc.
Inventor： Kiran Amancha , Shivani Chilampalli , Thrimoorthy Potta , Ningxin Yan , Venkat R. Goskonda
Abstract: The invention provides stable liquid formulations containing naloxone, a pharmaceutically acceptable salt or a derivative thereof. The invention further provides methods for treating opioid dependence, opioid overdose, and congenital insensitivity to pain with anhidrosis by administering the liquid formulations of the present invention both intranasally and sublingually to a patient in need thereof. Further, the invention provides a method of treating opioid dependence, opioid overdose, and congenital insensitivity to pain with anhidrosis by administering intranasally and sublingually the naloxone formulations of the present invention.
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公开(公告)号：US20180289639A1
公开(公告)日：2018-10-11
申请号：US16007998
申请日：2018-06-13
Applicant: Insys Development Company, Inc.
Inventor： Thrimoorthy Potta , Craig Bastian , Ningxin Yan , Venkat Goskonda , Chandeshwari Chilampalli , Rachana Inavolu , Eshwaran Narayanan
Abstract: The present invention is directed to epinephrine spray formulations. The present invention is further directed to methods of treating anaphylaxis by administering epinephrine spray formulations to subjects in need of such treatments.
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公开(公告)号：US10441538B2
公开(公告)日：2019-10-15
申请号：US15876553
申请日：2018-01-22
Applicant: Insys Development Company, Inc.
Inventor： Kiran Amancha , Chandeshwari Chilampalli , Thrimoorthy Potta , Ningxin Yan , Venkat R. Goskonda , Eshwaran Narayanan
Abstract: The invention provides stable liquid formulations containing naloxone, a pharmaceutically acceptable salt or a derivative thereof. The invention further provides methods for treating opioid overdose, opioid dependence, and congenital insensitivity to pain with anhidrosis by administering the liquid formulations of the present invention intranasally to a patient in need thereof. Further, the invention provides a method of treating opioid dependence, opioid overdose, and congenital insensitivity to pain with anhidrosis by administering intranasally the naloxone formulations of the present invention.
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公开(公告)号：US20190216750A1
公开(公告)日：2019-07-18
申请号：US16290853
申请日：2019-03-01
Applicant: Insys Development Company, Inc.
Inventor： Thrimoorthy Potta , Craig Bastian , Ningxin Yan , Venkat Goskonda , Chandeshwari Chilampalli , Rachana Inavolu , Eshwaran Narayanan
CPC classification number: A61K31/137 , A61K9/0043 , A61K47/02 , A61K47/10 , A61K47/183 , A61K47/186 , A61P37/08
Abstract: The present invention is directed to epinephrine spray formulations. The present invention is further directed to methods of treating anaphylaxis by administering epinephrine spray formulations to subjects in need of such treatments.
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公开(公告)号：US20180289617A1
公开(公告)日：2018-10-11
申请号：US16007999
申请日：2018-06-13
Applicant: Insys Development Company, Inc.
Inventor： Thrimoorthy Potta , Craig Bastian , Ningxin Yan , Venkat Goskonda , Chandeshwari Chilampalli , Rachana Inavolu , Eshwaran Narayanan
IPC: A61K9/00 , A61K9/08 , A61K31/137 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/18 , A61K47/20 , A61K47/22 , A61P11/02
Abstract: The present invention is directed to epinephrine spray formulations. The present invention is further directed to methods of treating anaphylaxis by administering epinephrine spray formulations to subjects in need of such treatments.
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Patent Agency Ranking
公开(公告)号：US10039710B2
公开(公告)日：2018-08-07
申请号：US15488712
申请日：2017-04-17
Applicant: Insys Development Company, Inc.
Inventor： Thrimoorthy Potta , Craig Bastian , Ningxin Yan , Venkat Goskonda , Chandeshwari Chilampalli , Rachana Inavolu , Eshwaran Narayanan
CPC classification number: A61K9/0043 , A61K9/006 , A61K9/0073 , A61K9/0078 , A61K9/08 , A61K31/137 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/183 , A61K47/26 , A61K47/36
Abstract: The present invention is directed to epinephrine spray formulations. The present invention is further directed to methods of treating anaphylaxis by administering epinephrine spray formulations to subjects in need of such treatments.
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公开(公告)号：US20180147143A1
公开(公告)日：2018-05-31
申请号：US15876553
申请日：2018-01-22
Applicant: Insys Development Company, Inc.
Inventor： Kiran Amancha , Chandeshwari Chilampalli , Thrimoorthy Potta , Ningxin Yan , Venkat R. Goskonda
CPC classification number: A61K9/08 , A61K9/0043 , A61K31/485 , A61K47/10 , A61K47/12 , A61P25/36
Abstract: The invention provides stable liquid formulations containing naloxone, a pharmaceutically acceptable salt or a derivative thereof. The invention further provides methods for treating opioid overdose, opioid dependence, and congenital insensitivity to pain with anhidrosis by administering the liquid formulations of the present invention intranasally to a patient in need thereof. Further, the invention provides a method of treating opioid dependence, opioid overdose, and congenital insensitivity to pain with anhidrosis by administering intranasally the naloxone formulations of the present invention.
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公开(公告)号：US20160287593A1
公开(公告)日：2016-10-06
申请号：US15089490
申请日：2016-04-02
Applicant: Insys Development Company, Inc.
Inventor： Thrimoorthy Potta , Kiran Amancha , Wesley Giron , Ningxing Yan , Venkat Goskonda , Onkar N. Singh
IPC: A61K31/519 , A61K47/12 , A61K47/10 , A61K9/00 , A61K47/02
CPC classification number: A61K31/519 , A61K9/006 , A61K47/02 , A61K47/10 , A61K47/12
Abstract: The invention is directed to sublingual spray formulations containing sildenafil. The invention is further directed to methods of treating male sexual dysfunction or pulmonary arterial hypertension by administering sublingual spray formulations containing sildenafil to patients in need of such treatments.
Abstract translation: 本发明涉及含西地那非的舌下喷雾制剂。 本发明进一步涉及通过向需要这种治疗的患者施用含有西地那非的舌下喷雾制剂来治疗男性性功能障碍或肺动脉高压的方法。
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公开(公告)号：US20190209494A1
公开(公告)日：2019-07-11
申请号：US16242101
申请日：2019-01-08
Applicant: Insys Development Company, Inc.
Inventor： Eshwaran Narayanan , Rajesh Wakaskar , Chandeshwari Chilampalli , Thrimoorthy Potta , Venkat R. Goskonda
CPC classification number: A61K31/137 , A61J1/00 , A61K9/0043 , A61K47/02 , A61K47/10 , A61K47/186
Abstract: The present invention is directed to methods of stabilizing a pharmaceutical composition comprising epinephrine containing the steps filling a container, capping the container, assembling the container and placing the assembled capped container (assembled device) in a secondary packaging system.
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公开(公告)号：US20170252337A1
公开(公告)日：2017-09-07
申请号：US15601331
申请日：2017-05-22
Applicant: Insys Development Company, Inc.
Inventor： Kiran Amancha , Shivani Chilampalli , Thrimoorthy Potta , Ningxin Yan , Venkat R. Goskonda
IPC: A61K31/485 , A61K9/08 , A61K9/00 , A61K47/10 , A61K47/18
CPC classification number: A61K31/485 , A61K9/0043 , A61K9/006 , A61K9/08 , A61K47/10 , A61K47/183
Abstract: The invention provides stable liquid formulations containing naloxone, a pharmaceutically acceptable salt or a derivative thereof. The invention further provides methods for treating opioid dependence, opioid overdose, and congenital insensitivity to pain with anhidrosis by administering the liquid formulations of the present invention intranasally to a patient in need thereof. Further, the invention provides a method of treating opioid dependence, opioid overdose, and congenital insensitivity to pain with anhidrosis by administering intranasally the naloxone formulations of the present invention.
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