公开(公告)号：US20090030310A1

公开(公告)日：2009-01-29

申请号：US11881342

申请日：2007-07-26

Applicant: James J. Hamill ,  David D. Faul ,  William Curtis Howe

Inventor： James J. Hamill ,  David D. Faul ,  William Curtis Howe

IPC: A61B6/00 ,  A61B8/00

CPC classification number: A61B8/12 ,  A61B6/037 ,  A61B6/4258 ,  A61B6/4417 ,  A61B8/4416 ,  G01T1/161

Abstract: A system for dual-mode medical imaging is provided. The system features components for PET imaging as well as for ultrasonic imaging, with an internal probe that has components to provide capability for both. The system provides cost-efficient PET imaging for smaller regions and organs of interest than conventional full body PET scanner apparatus.

Abstract translation: 提供了一种双模式医学成像系统。 该系统具有用于PET成像以及超声成像的组件，内部探针具有为两者提供能力的组件。 该系统为传统全身PET扫描仪装置的较小区域和器官提供了具有成本效益的PET成像。

公开(公告)号：US06774358B2

公开(公告)日：2004-08-10

申请号：US10103276

申请日：2002-03-21

Applicant: James J. Hamill ,  Michael E. Casey ,  Timothy G. Gremillion ,  Wing K. Luk ,  Stephen Miller

Inventor： James J. Hamill ,  Michael E. Casey ,  Timothy G. Gremillion ,  Wing K. Luk ,  Stephen Miller

IPC: G01K500

CPC classification number: G01T1/2985 ,  A61B6/037 ,  G01T1/1644

Abstract: Apparatus and methods for simulating a sheet source with a line source for determining normalization coefficients for the detectors in positron emission tomography (PET) scanners and single photon emission computed tomography (SPECT) scanners. A line source, oriented perpendicular to the axis of a scanner gantry, is moved along the axis while the detectors are stationary and positioned substantially parallel to the plane in which the source moves. In another embodiment, an axially mounted line source moves parallel to a diameter of the gantry while the stationary detectors are positioned substantially parallel to the plane in which the source moves. In still another embodiment, the line source is stationary and positioned parallel to the gantry axis and off center while the detectors move relative to the line source. A shaped attenuator is placed around the source in this last embodiment.

Abstract translation: 用于模拟具有用于确定正电子发射断层摄影（PET）扫描仪和单光子发射计算机断层摄影（SPECT）扫描仪中的检测器的归一化系数的线源的片材源的装置和方法。 垂直于扫描仪台架的轴线定向的线源沿轴线移动，同时检测器是固定的并且基本上平行于源移动的平面定位。 在另一个实施例中，轴向安装的线源平行于台架的直径移动，而固定检测器基本上平行于源移动的平面定位。 在另一个实施例中，线源固定并且平行于台架轴定位并且离开中心，同时检测器相对于线源移动。 在最后一个实施例中，围绕源设置成形的衰减器。

公开(公告)号：US5757006A

公开(公告)日：1998-05-26

申请号：US790833

申请日：1997-01-30

Applicant: Raymond P. DeVito ,  James J. Hamill

Inventor： Raymond P. DeVito ,  James J. Hamill

IPC: G01T1/164 ,  G01T1/24 ,  G01T1/161

CPC classification number: G01T1/1642 ,  G01T1/249 ,  A61B6/037

Abstract: An articulating detector array for gamma cameras is disclosed which is adaptable to perform different imaging techniques in a single apparatus. The articulating detector array is adapted to detect incident gamma radiation from diverse directions as well as Compton scattering thereof without the need of a collimator, as so has improved gamma ray detection efficiency. The detector array includes radiation detectors in an array and movable to a plurality of positions, in which each radiation detector is responsive to gamma radiation from a target for generating detection signals for use in tomographic imaging of the source. The detector array includes articulating support structures for mounting the detectors to the base and for moving the detectors from a first position to a second position. In one embodiment, the articulating support structures includes a first portion connected to a detector; and a second portion connected to the base, in which the first portion is adapted to extend from the second portion from the first position to the second position. In another embodiment, the articulating support structures include a pivot for pivotably mounting the detectors and for rotating the detectors from a first position to a second position.

Abstract translation: 公开了一种用于伽马照相机的关节式检测器阵列，其适用于在单个装置中执行不同的成像技术。 铰接检测器阵列适于从不同方向检测入射伽马射线以及其康普顿散射，而不需要准直器，因此伽马射线检测效率得到改善。 检测器阵列包括阵列中的辐射检测器并且可移动到多个位置，其中每个辐射检测器响应来自目标的伽马射线，用于产生用于源的断层成像的检测信号。 检测器阵列包括用于将检测器安装到基座并用于将检测器从第一位置移动到第二位置的铰接支撑结构。 在一个实施例中，铰接支撑结构包括连接到检测器的第一部分; 以及连接到所述基座的第二部分，其中所述第一部分适于从所述第二部分从所述第一位置延伸到所述第二位置。 在另一个实施例中，铰接支撑结构包括用于可枢转地安装检测器并用于将检测器从第一位置转动到第二位置的枢轴。

公开(公告)号：US20100063378A1

公开(公告)日：2010-03-11

申请号：US12558159

申请日：2009-09-11

Applicant: James J. Hamill ,  Carl Eric Arnsdorff

Inventor： James J. Hamill ,  Carl Eric Arnsdorff

IPC: A61B6/04

CPC classification number: A61B6/037 ,  A61B5/103 ,  A61B6/0421 ,  A61B6/482

Abstract: A constraint having a main body and at least one coupler. The main body can be substantially arcuate in shape and can be configured to constrain a patient. The at least one coupler can couple the main body to a bed or treatment pallet. The constraint can be sized to restrict a patient within a computerized tomography (CT) scan field of view.

Abstract translation: 具有主体和至少一个耦合器的约束。 主体可以是基本上弓形的形状，并且可以构造成约束患者。 所述至少一个联接器可以将主体连接到床或处理托盘。 该约束的大小可以限制在计算机断层摄影（CT）扫描视野内的患者。

公开(公告)号：US07676073B2

公开(公告)日：2010-03-09

申请号：US11550445

申请日：2006-10-18

Applicant: James J. Hamill ,  David D. Faul

Inventor： James J. Hamill ,  David D. Faul

IPC: G06K9/00 ,  A61B6/00

CPC classification number: G06T11/005

Abstract: A method of reducing ring artifacts in tomographic images including providing an original digitized projection measurement comprising a plurality of intensities corresponding to a domain of points on an 2-dimensional grid, operating on said original projection measurement with a filter wherein features of high radial frequency and low angular frequency are attenuated, forming a weighted mixture of said filtered projection measurement and said original projection measurement wherein ring artifacts in said original tomographic image are substantially reduced, and reconstructing the projection measurement to form a tomographic image. Alternatively, a first tomographic image is reconstructed from said original projection measurement, a second tomographic image is reconstructed from said filtered projection measurement, and a weighted mixture is formed from said first tomographic image and said second tomographic image.

Abstract translation: 一种降低断层图像中的环形伪影的方法，包括提供原始的数字化投影测量，该原始数字化投影测量包括对应于二维网格上的点的区域的多个强度，用滤波器对所述原始投影测量进行操作，其中高径向频率和 低角频率被衰减，形成所述滤波投影测量和所述原始投影测量的加权混合，其中所述原始断层图像中的环形伪影被大大减少，并且重建投影测量以形成断层图像。 或者，从所述原始投影测量重建第一断层图像，从所述滤波投影测量重建第二断层图像，并且从所述第一断层图像和所述第二断层图像形成加权混合。

公开(公告)号：US20080056549A1

公开(公告)日：2008-03-06

申请号：US11550445

申请日：2006-10-18

Applicant: James J. Hamill ,  David D. Faul

Inventor： James J. Hamill ,  David D. Faul

IPC: G06K9/00 ,  G06K9/40

CPC classification number: G06T11/005

Abstract: A method of reducing ring artifacts in tomographic images including providing an original digitized projection measurement comprising a plurality of intensities corresponding to a domain of points on an 2-dimensional grid, operating on said original projection measurement with a filter wherein features of high radial frequency and low angular frequency are attenuated, forming a weighted mixture of said filtered projection measurement and said original projection measurement wherein ring artifacts in said original tomographic image are substantially reduced, and reconstructing the projection measurement to form a tomographic image. Alternatively, a first tomographic image is reconstructed from said original projection measurement, a second tomographic image is reconstructed from said filtered projection measurement, and a weighted mixture is formed from said first tomographic image and said second tomographic image.

Abstract translation: 一种降低断层图像中的环形伪影的方法，包括提供原始的数字化投影测量，该原始数字化投影测量包括对应于二维网格上的点的区域的多个强度，用滤波器对所述原始投影测量进行操作，其中高径向频率和 低角频率被衰减，形成所述滤波投影测量和所述原始投影测量的加权混合，其中所述原始断层图像中的环形伪影被大大减少，并且重建投影测量以形成断层图像。 或者，从所述原始投影测量重建第一断层图像，从所述滤波投影测量重建第二断层图像，并且从所述第一断层图像和所述第二断层图像形成加权混合。

公开(公告)号：US06963065B2

公开(公告)日：2005-11-08

申请号：US10418520

申请日：2003-04-18

Applicant: Maurizio Conti ,  James J. Hamill ,  Michael E. Casey ,  Mu Chen

Inventor： Maurizio Conti ,  James J. Hamill ,  Michael E. Casey ,  Mu Chen

IPC: G01D18/00 ,  G01T1/172 ,  G01T1/29 ,  G12B13/00

CPC classification number: G01T1/2985 ,  A61B6/037

Abstract: A normalization apparatus and method for a PET scanner with panel detectors for obtaining an estimate of a normalization array, for correction for count rate effects on the normalization array, and for measurement of the relation between the normalization array and the count rate. The method of the present invention is based on two quasi-independent radial and axial components, which are count rate dependent due to sensitivity changes across the detector blocks. A scatter source is disposed at the center of the FOV and a scatter-free source is disposed at the outer edge of the FOV. The method computes the normalization array through several steps which evaluate the geometric profile, the axial profile, and the correction factor. A count rate correction is introduced to extend the normalization array to any count rate.

Abstract translation: 一种具有面板检测器的PET扫描仪的归一化装置和方法，用于获得归一化阵列的估计，用于校正对归一化阵列的计数率影响，以及用于测量归一化阵列与计数率之间的关系。 本发明的方法是基于两个准独立的径向和轴向分量，其由于检测器块两端的灵敏度变化而依次计数。 散射源设置在FOV的中心，并且不分散源设置在FOV的外边缘处。 该方法通过评估几何轮廓，轴向轮廓和校正因子的几个步骤来计算归一化阵列。 引入计数率校正以将归一化数组扩展到任何计数率。

公开(公告)号：US20140051977A9

公开(公告)日：2014-02-20

申请号：US13248089

申请日：2011-09-29

Applicant: James J. Hamill ,  Ludovic Le Meunier

Inventor： James J. Hamill ,  Ludovic Le Meunier

IPC: A61B5/055 ,  A61B5/05

CPC classification number: A61B5/7292 ,  A61B5/1135 ,  A61B6/037 ,  A61B6/541 ,  G01R33/481 ,  G01R33/5676

Abstract: Methods and computer-readable mediums are provided for obtaining an optimally gated medical image. For example, in one embodiment, a method is provided that acquires medical images in list mode. The method also acquires a respiration correlated signal S(t). Thereafter, a final upper strain threshold value and a final lower strain threshold value pair that has a narrowest interval are selected. The medical images are synchronized with the respiration correlated signal S(t). The synchronized images and signal are used to create an optimally gated medical image. In various embodiments, the disclosed optimal gating can be utilized in PET systems and in other embodiments the disclosed optimal gating can be utilized in SPECT systems. In yet other embodiments, the optimally gated images can be matched to MRI systems and in still other embodiments, the optimally gated images can be matched to CT systems.

Abstract translation: 提供方法和计算机可读介质以获得最佳门控的医学图像。 例如，在一个实施例中，提供了以列表模式获取医学图像的方法。 该方法还获取呼吸相关信号S（t）。 此后，选择具有最窄间隔的最终上应变阈值和最终下应变阈值对。 医学图像与呼吸相关信号S（t）同步。 同步的图像和信号用于创建最佳门控的医学图像。 在各种实施例中，所公开的最佳选通可用于PET系统中，并且在其它实施例中，所公开的最佳门控可用于SPECT系统。 在其他实施例中，最佳门控图像可以与MRI系统匹配，并且在其他实施例中，最佳门控图像可以与CT系统匹配。

公开(公告)号：US08565856B2

公开(公告)日：2013-10-22

申请号：US12125329

申请日：2008-05-22

Applicant: James J. Hamill ,  Günther Platsch ,  Michael E. Casey

Inventor： James J. Hamill ,  Günther Platsch ,  Michael E. Casey

IPC: A61B5/05

CPC classification number: A61B8/08 ,  A61B5/7285 ,  A61B6/032 ,  A61B6/5247 ,  A61B6/541 ,  A61B8/4245 ,  A61B8/5238 ,  A61B8/543 ,  G01T1/1603

Abstract: A medical imaging device has an emission tomograph, at least one ultrasonic (US) probe for providing images giving real-time information about the location of the internal organs of a subject, a tracking system for spatially locating the at least one ultrasonic probe in relation to the medical imaging device, and an image processing unit in which the location information obtained by the ultrasonic probe is used for attenuation correction of image information obtained by the emission tomograph.

Abstract translation: 一种医疗成像装置具有发射断层摄影机，至少一个超声波（US）探头，用于提供给出关于被检体的内部器官的位置的实时信息的图像，用于相对于空间定位至少一个超声波探头的跟踪系统 以及图像处理单元，其中由超声波探头获得的位置信息用于由发射断层摄影机获得的图像信息的衰减校正。

公开(公告)号：US20120069946A1

公开(公告)日：2012-03-22

申请号：US12887933

申请日：2010-09-22

Applicant: James J. Hamill ,  Stefan B. Siegel ,  Charles Russell Buchanan

Inventor： James J. Hamill ,  Stefan B. Siegel ,  Charles Russell Buchanan

IPC: G21G1/06

CPC classification number: G21G1/06 ,  G21G2001/0094

Abstract: Disclosed are a method and apparatus for making a radioisotope and a composition of matter including the radioisotope. The radioisotope is made by exposing a material to neutrons from a portable neutron source.

Abstract translation: 公开了制备放射性同位素的方法和装置以及包括放射性同位素的物质组成。 放射性同位素是通过将材料从便携式中子源暴露于中子而制成的。