公开(公告)号：US10689341B2

公开(公告)日：2020-06-23

申请号：US16099853

申请日：2017-05-10

Applicant: King Abdullah University of Science and Technology

Inventor： Xinbo Wang ,  Zhiping Lai ,  Yupeng Pan ,  Kuowei Huang ,  Zhigang Wang

IPC: C07D209/08 ,  C07D209/16 ,  C07D209/24 ,  C07D209/48 ,  A61K31/404 ,  A61K31/4045 ,  A61K45/06 ,  C07D209/14 ,  C07D209/26 ,  C07D403/06

Abstract: The invention relates to novel N-(α-peroxy)indole compounds of Formula I and methods for use. (I) The N-(α-peroxy)indole compounds described herein are useful for treating or preventing parastic infections, bacterial infections, and cancer in subjects. The methods include administering an N-(α-peroxy)indole compound as described herein to a subject. Also described herein are methods for synthesizing N-(α-peroxy)indole compounds.