公开(公告)号：US20210140876A1

公开(公告)日：2021-05-13

申请号：US16952654

申请日：2020-11-19

Applicant: Labrador Diagnostics LLC

Inventor： Karan Mohan ,  Samartha Anekal

IPC: G01N21/25 ,  G01N21/76 ,  G01N21/64

Abstract: The devices and systems disclosed herein provide multiple optical capabilities in a single device or system. Methods for using these devices and systems are provided. These devices and systems are configurable for operation in each of a spectroscopy mode, a fluorescence mode, and a luminescence mode, and are capable of performing spectroscopic, fluorescence, and luminescence observations, measurements, and analyses when operated in the corresponding spectroscopy mode, fluorescence mode, or luminescence mode. These devices and systems include mirror dispersion elements having multiple faces including an optical dispersion element on one face (e.g., a diffraction grating or a prism) and a reflective element on another face (e.g., a mirror). These multiple capabilities eliminate the need to move or load a sample in multiple devices when subjecting a sample to multiple analyses, and thus provide greater accuracy, precision, and speed while reducing complexity and cost of sample analysis.

公开(公告)号：US20210123862A1

公开(公告)日：2021-04-29

申请号：US17011197

申请日：2020-09-03

Applicant: Labrador Diagnostics LLC

Inventor： Karan Mohan ,  Chinmay Pangarkar

IPC: G01N21/47 ,  G01N15/14 ,  G01N21/64 ,  G02B26/00 ,  B01L3/00

Abstract: Methods, devices, apparatus, and systems are provided for image analysis. Methods of image analysis may include observation, measurement, and analysis of images of biological and other samples; devices, apparatus, and systems provided herein are useful for observation, measurement, and analysis of images of such samples. The methods, devices, apparatus, and systems disclosed herein provide advantages over other methods, devices, apparatus, and systems.

公开(公告)号：US10768105B1

公开(公告)日：2020-09-08

申请号：US15664580

申请日：2017-07-31

Applicant: Labrador Diagnostics LLC

Inventor： Karan Mohan ,  Chinmay Pangarkar

IPC: G01N21/47 ,  G01N15/14 ,  G01N21/64 ,  G02B26/00 ,  B01L3/00

Abstract: Methods, devices, apparatus, and systems are provided for image analysis. Methods of image analysis may include observation, measurement, and analysis of images of biological and other samples; devices, apparatus, and systems provided herein are useful for observation, measurement, and analysis of images of such samples. The methods, devices, apparatus, and systems disclosed herein provide advantages over other methods, devices, apparatus, and systems.

公开(公告)号：US20210148908A1

公开(公告)日：2021-05-20

申请号：US17082979

申请日：2020-10-28

Applicant: Labrador Diagnostics LLC

Inventor： Chinmay Pangarkar ,  Karan Mohan ,  James R. Wasson

IPC: G01N33/569 ,  B01L3/00 ,  G01N15/10 ,  G02B21/00 ,  G02B21/12 ,  G01N21/05 ,  G02B21/08 ,  G01N33/50 ,  G01N1/30 ,  G01N33/53 ,  G01N33/58 ,  G01N21/64 ,  G02B7/09 ,  G01N21/03 ,  G01N21/17 ,  G02B21/24 ,  G01N33/487 ,  G01N33/49 ,  G01N21/27 ,  G02B21/16 ,  G02B21/36

Abstract: Methods, devices, systems, and apparatuses are provided for the image analysis of measurement of biological samples.

公开(公告)号：US10823731B2

公开(公告)日：2020-11-03

申请号：US14600630

申请日：2015-01-20

Applicant: Labrador Diagnostics LLC

Inventor： Chinmay Pangarkar ,  Karan Mohan ,  James R. Wasson

IPC: G01N33/49 ,  G02B7/09 ,  G02B21/16 ,  G01N21/17 ,  G01N33/569 ,  B01L3/00 ,  G01N15/10 ,  G02B21/00 ,  G02B21/12 ,  G01N21/05 ,  G02B21/08 ,  G01N33/50 ,  G01N1/30 ,  G01N21/64 ,  G01N21/03 ,  G02B21/24 ,  G01N33/487 ,  G01N21/27 ,  G02B21/36

Abstract: Methods, devices, systems, and apparatuses are provided for the image analysis of measurement of biological samples. Specifically, methods are provided for detecting and measuring, in a sample, cell morphology; measurement of cell numbers; detection of particles; measurement of particle numbers; and other properties and quantities of or in a sample. Some embodiments may use a sample holder comprising a sample chamber configured to hold said sample, at least a portion of said sample holder comprising an optically transmissive material, said optically transmissive material comprising an optically transmissive surface and a reflective surface.

公开(公告)号：US12111248B2

公开(公告)日：2024-10-08

申请号：US16382489

申请日：2019-04-12

Applicant: Labrador Diagnostics LLC

Inventor： Karan Mohan ,  Chinmay Pangarkar ,  James R. Wasson

IPC: G01N21/03 ,  B01L3/00 ,  B01L9/00 ,  G01N1/30 ,  G01N15/10 ,  G01N21/05 ,  G01N21/17 ,  G01N21/27 ,  G01N21/64 ,  G01N33/487 ,  G01N33/49 ,  G01N33/50 ,  G01N33/569 ,  G02B7/09 ,  G02B21/00 ,  G02B21/08 ,  G02B21/12 ,  G02B21/16 ,  G02B21/24 ,  G02B21/34 ,  G02B21/36 ,  G01N15/01 ,  G01N15/14

CPC classification number: G01N21/0303 ,  B01L3/502715 ,  B01L3/5085 ,  B01L9/523 ,  G01N1/30 ,  G01N15/1012 ,  G01N21/05 ,  G01N21/17 ,  G01N21/27 ,  G01N21/6428 ,  G01N21/645 ,  G01N21/6458 ,  G01N21/6486 ,  G01N33/487 ,  G01N33/49 ,  G01N33/5005 ,  G01N33/56966 ,  G01N33/56972 ,  G02B7/09 ,  G02B21/00 ,  G02B21/0076 ,  G02B21/088 ,  G02B21/125 ,  G02B21/16 ,  G02B21/244 ,  G02B21/34 ,  G02B21/365 ,  G02B21/367 ,  B01L2300/0654 ,  B01L2300/168 ,  G01N15/01 ,  G01N2015/1014 ,  G01N2015/1486 ,  G01N2021/1738 ,  G01N2021/6439 ,  G01N2201/061 ,  G01N2201/068 ,  G01N2201/12 ,  G01N2333/70589 ,  G01N2333/70596

Abstract: Methods, devices, apparatus, and systems are provided for image analysis. Methods of image analysis may include observation, measurement, and analysis of images of biological and other samples; devices, apparatus, and systems provided herein are useful for observation, measurement, and analysis of images of such samples. The methods, devices, apparatus, and systems disclosed herein provide advantages over other methods, devices, apparatus, and systems.

公开(公告)号：US11309856B2

公开(公告)日：2022-04-19

申请号：US17011129

申请日：2020-09-03

Applicant: Labrador Diagnostics LLC

Inventor： Karan Mohan ,  Marcelo Martinez

IPC: H03G3/00 ,  H01L31/02 ,  G01N15/14 ,  H03F3/08 ,  H03M1/06 ,  H03F3/45 ,  G01N21/64 ,  G01N15/06 ,  G01N15/10

Abstract: In one embodiment, a femtowatt sensitivity optical detector is provided using one or more photodiodes, intended as a replacement for the photomultiplier based photon counting unit.

公开(公告)号：US12066440B2

公开(公告)日：2024-08-20

申请号：US17082979

申请日：2020-10-28

Applicant: Labrador Diagnostics LLC

Inventor： Chinmay Pangarkar ,  Karan Mohan ,  James R. Wasson

IPC: B01L3/00 ,  B01F23/00 ,  B01F23/41 ,  B01F101/23 ,  B23Q17/24 ,  C08L5/08 ,  C12M1/34 ,  C12Q1/04 ,  C12Q1/18 ,  G01N1/30 ,  G01N15/10 ,  G01N21/03 ,  G01N21/05 ,  G01N21/17 ,  G01N21/27 ,  G01N21/3577 ,  G01N21/359 ,  G01N21/39 ,  G01N21/45 ,  G01N21/64 ,  G01N30/12 ,  G01N30/68 ,  G01N30/70 ,  G01N30/72 ,  G01N30/88 ,  G01N33/00 ,  G01N33/18 ,  G01N33/487 ,  G01N33/49 ,  G01N33/50 ,  G01N33/53 ,  G01N33/564 ,  G01N33/569 ,  G01N33/58 ,  G01N33/68 ,  G02B7/09 ,  G02B21/00 ,  G02B21/08 ,  G02B21/12 ,  G02B21/16 ,  G02B21/24 ,  G02B21/36

CPC classification number: G01N33/56972 ,  B01L3/502715 ,  G01N1/30 ,  G01N15/1012 ,  G01N21/0303 ,  G01N21/05 ,  G01N21/17 ,  G01N21/27 ,  G01N21/6428 ,  G01N21/645 ,  G01N21/6458 ,  G01N21/6486 ,  G01N33/487 ,  G01N33/49 ,  G01N33/5005 ,  G01N33/53 ,  G01N33/5308 ,  G01N33/56966 ,  G01N33/582 ,  G02B7/09 ,  G02B21/0076 ,  G02B21/088 ,  G02B21/125 ,  G02B21/16 ,  G02B21/244 ,  G02B21/365 ,  G01N2015/1014 ,  G01N2021/1738 ,  G01N2021/6439 ,  G01N2201/061 ,  G01N2201/12 ,  G01N2333/70589 ,  G01N2333/70596

Abstract: Methods, devices, systems, and apparatuses are provided for the image analysis of measurement of biological samples.

公开(公告)号：US11300564B2

公开(公告)日：2022-04-12

申请号：US15278333

申请日：2016-09-28

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Chinmay Pangarkar ,  Timothy Smith ,  Karan Mohan ,  Daniel Young ,  James Wasson ,  Samartha Anekal

IPC: G01N33/569 ,  B01L3/00 ,  G01N15/10 ,  G02B21/00 ,  G02B21/12 ,  G01N21/05 ,  G02B21/08 ,  G01N33/50 ,  G01N1/30 ,  G01N33/53 ,  G01N33/58 ,  G01N21/64 ,  G02B7/09 ,  G01N21/03 ,  G01N21/17 ,  G02B21/24 ,  G01N33/487 ,  G01N33/49 ,  G01N21/27 ,  G02B21/16 ,  G02B21/36

Abstract: Methods, devices, systems, and apparatuses are provided for the image analysis of measurement of biological samples.

公开(公告)号：US11262308B2

公开(公告)日：2022-03-01

申请号：US17078936

申请日：2020-10-23

Applicant: Labrador Diagnostics LLC

Inventor： Chinmay Pangarkar ,  Karan Mohan

IPC: G01N21/64 ,  G01N21/47 ,  G01N15/14

Abstract: Methods and devices for cytometric analysis are provided. A cytometry apparatus is provided which may be used with a stationary sample cuvette for analysis of a stationary sample or with a flow sample cuvette for analysis of a flowing sample. The methods and devices provided herein may be used to perform cytometric analysis of samples under a wide range of experimental and environmental conditions.