公开(公告)号：US20230035908A1

公开(公告)日：2023-02-02

申请号：US17706102

申请日：2022-03-28

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Shaunak Roy ,  Ian Gibbons ,  Shize Daniel Qi ,  Edmond Ku ,  Chris Todd ,  Melissa Takahashi ,  Bruce Johnson ,  Jeff Fenton ,  Keith Moravick ,  Uwe Springborn ,  Anthony Delacruz

IPC: G01N33/53 ,  A61B5/15 ,  A61B5/1486 ,  A61B5/00 ,  G01N33/536 ,  G01N33/573

Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

公开(公告)号：US10908093B2

公开(公告)日：2021-02-02

申请号：US14867271

申请日：2015-09-28

Applicant: Labrador Diagnostics LLC

Inventor： Ian Gibbons ,  Chengwang Wang ,  Shaunak Roy ,  Elizabeth A. Holmes

IPC: G01N21/76 ,  G01N33/53 ,  B01L3/00 ,  A61B5/151 ,  A61B5/157 ,  A61B5/145 ,  A61B5/00 ,  G16H40/63 ,  A61B5/15 ,  G01N33/50 ,  A61B5/155 ,  G01N33/543 ,  A61B5/1495

Abstract: The present invention provides methods of calibrating a fluidic device useful for detecting an analyte of interest in a bodily fluid. The invention also provides methods for assessing the reliability of an assay for an analyte in a bodily fluid with the use of a fluidic device. Another aspect of the invention is a method for performing a trend analysis on the concentration of an analyte in a subject using a fluidic device.

公开(公告)号：US10761030B2

公开(公告)日：2020-09-01

申请号：US14481264

申请日：2014-09-09

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Ian Gibbons ,  Timothy M. Kemp ,  John Howard ,  Shaunak Roy

IPC: G01N21/76 ,  B01L3/00 ,  G01N33/53 ,  A61B5/151 ,  A61B5/157 ,  A61B5/145 ,  A61B5/00 ,  G16H40/63 ,  A61B5/15 ,  G01N33/50 ,  A61B5/155 ,  G01N33/543 ,  A61B5/1495

Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

公开(公告)号：US11802882B2

公开(公告)日：2023-10-31

申请号：US16222845

申请日：2018-12-17

Applicant: Labrador Diagnostics LLC

Inventor： Ian Gibbons ,  Shaunak Roy ,  Edmond Ku

IPC: G01N33/92 ,  B01L3/00 ,  G01N21/31 ,  G01N33/53 ,  C12Q1/60 ,  G01N21/27 ,  G01N33/52

CPC classification number: G01N33/92 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/502753 ,  C12Q1/60 ,  G01N21/27 ,  G01N21/31 ,  G01N33/525 ,  G01N33/5302 ,  B01L2200/0605 ,  B01L2200/0631 ,  B01L2200/10 ,  B01L2300/0654 ,  B01L2300/087 ,  B01L2300/0819 ,  B01L2300/0874 ,  B01L2300/0887 ,  B01L2300/168 ,  G01N2201/061 ,  G01N2201/062 ,  Y10T436/20

Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

公开(公告)号：US11754554B2

公开(公告)日：2023-09-12

申请号：US15403553

申请日：2017-01-11

Applicant: Labrador Diagnostics LLC

Inventor： Shaunak Roy ,  Melissa Takahashi ,  Ian Gibbons ,  Edmond Ku ,  Thanh Dang ,  Tammy Burd ,  Adam Vollmer ,  Elizabeth A. Holmes

IPC: G01N33/53 ,  G01N35/10 ,  G01N33/49 ,  G01N27/07 ,  G01N33/86 ,  G01N27/06

CPC classification number: G01N33/5304 ,  G01N27/07 ,  G01N33/49 ,  G01N33/5302 ,  G01N33/86 ,  G01N35/1002 ,  G01N27/06 ,  G01N2201/12746 ,  G01N2800/52 ,  Y10S435/973 ,  Y10S436/809 ,  Y10T436/106664

Abstract: The present invention provides fluidic devices and systems that allow detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

公开(公告)号：US11630069B2

公开(公告)日：2023-04-18

申请号：US15689905

申请日：2017-08-29

Applicant: Labrador Diagnostics LLC

Inventor： Timothy Michael Kemp ,  Chris Todd ,  Ron Oral ,  Shulin Zeng ,  John Howard ,  Jeff Fenton ,  Elizabeth A. Holmes ,  Ian Gibbons ,  Shaunak Roy

IPC: G01N33/543 ,  G01N21/76 ,  A61B5/155 ,  A61B5/145 ,  A61B5/157 ,  A61B5/151 ,  A61B5/00 ,  B01L3/00 ,  G01N33/50 ,  G01N33/53 ,  G16H40/63 ,  A61B5/15 ,  A61B5/1495

Abstract: This invention is in the field of medical devices. Specifically, the present invention provides fluidic systems having a plurality of reaction sites surrounded by optical barriers to reduce the amount of optical cross-talk between signals detected from various reaction sites. The invention also provides a method of manufacturing fluidic systems and methods of using the systems.

公开(公告)号：US11287421B2

公开(公告)日：2022-03-29

申请号：US15951641

申请日：2018-04-12

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Shaunak Roy ,  Ian Gibbons ,  Shize Daniel Qi ,  Edmond Ku ,  Chris Todd ,  Melissa Takahashi ,  Bruce Johnson ,  Jeff Fenton ,  Keith Moravick ,  Uwe Springborn ,  Anthony Delacruz

IPC: B01L99/00 ,  G01N33/53 ,  A61B5/15 ,  A61B5/1486 ,  A61B5/00 ,  G01N33/536 ,  G01N33/573 ,  A61B5/151 ,  A61B5/157

Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

公开(公告)号：US20210055226A1

公开(公告)日：2021-02-25

申请号：US17007334

申请日：2020-08-31

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Ian Gibbons ,  Timothy K. Kemp ,  John Howard ,  Shaunak Roy

IPC: G01N21/76 ,  B01L3/00 ,  G01N33/53 ,  A61B5/151 ,  A61B5/157 ,  A61B5/145 ,  A61B5/00 ,  G16H40/63 ,  A61B5/15 ,  G01N33/50 ,  A61B5/155 ,  G01N33/543

Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

公开(公告)号：US20210262940A1

公开(公告)日：2021-08-26

申请号：US17164032

申请日：2021-02-01

Applicant: Labrador Diagnostics LLC

Inventor： Ian Gibbons (deceased) ,  Chengwang Wang ,  Shaunak Roy ,  Elizabeth A. Holmes

IPC: G01N21/76 ,  B01L3/00 ,  G01N33/53 ,  A61B5/151 ,  A61B5/157 ,  A61B5/145 ,  A61B5/00 ,  G16H40/63 ,  A61B5/15 ,  G01N33/50 ,  A61B5/155 ,  G01N33/543

Abstract: The present invention provides methods of calibrating a fluidic device useful for detecting an analyte of interest in a bodily fluid. The invention also provides methods for assessing the reliability of an assay for an analyte in a bodily fluid with the use of a fluidic device. Another aspect of the invention is a method for performing a trend analysis on the concentration of an analyte in a subject using a fluidic device.

公开(公告)号：US10712282B2

公开(公告)日：2020-07-14

申请号：US14481264

申请日：2014-09-09

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Ian Gibbons ,  Timothy M. Kemp ,  John Howard ,  Shaunak Roy

IPC: G01N21/76 ,  B01L3/00 ,  G01N33/53 ,  A61B5/151 ,  A61B5/157 ,  A61B5/145 ,  A61B5/00 ,  G16H40/63 ,  A61B5/15 ,  G01N33/50 ,  A61B5/155 ,  G01N33/543 ,  A61B5/1495

Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.