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    Multipath duty cycle enhancement for mass spectrometry
    5.
    发明授权
    Multipath duty cycle enhancement for mass spectrometry 有权

    公开(公告)号：US11004668B2

    公开(公告)日：2021-05-11

    申请号：US15315185

    申请日：2015-06-05

    Applicant: Micromass UK Limited

    Inventor： Martin Raymond Green ,  David J. Langridge ,  Keith Richardson ,  Jason Lee Wildgoose

    IPC: H01J49/00 ,  H01J49/06 ,  G01N27/624

    Abstract: A mass spectrometer is disclosed comprising a first device, a second device and a switch arranged and adapted: (i) to direct ions at a first time T1 to the first device and to substantially prevent ions from entering the second device; and (ii) to direct ions at a second later time T2 to the second device and to substantially prevent ions from entering the first device. At the first time T1 the second device may not be in an operational state to potentially optimally fragment, react, mass filter or otherwise process ions since the second device may be in a process of equilibration, changing state, re-filling, recharging, transition, replenishing, switching voltage or altering an operational parameter. Likewise, at the second time T2 the first device may not be in an operational state to potentially optimally fragment, react, mass filter or otherwise process ions since the first device may be in a process of equilibration, changing state, re-filling, recharging, transition, replenishing, switching voltage or altering an operational parameter.

    Hybrid mass spectrometer
    7.
    发明授权
    Hybrid mass spectrometer 有权

    公开(公告)号：US10886116B2

    公开(公告)日：2021-01-05

    申请号：US16789508

    申请日：2020-02-13

    Applicant: Micromass UK Limited

    Inventor： Kevin Giles ,  David J. Langridge ,  Steven Derek Pringle ,  Keith Richardson ,  Jason Lee Wildgoose

    IPC: H01J49/00 ,  H01J49/06 ,  G01N27/62 ,  H01J49/40

    Abstract: A method of mass spectrometry is disclosed comprising separating ions temporally in a first device 5 and analysing the mass or mass to charge ratio of the ions or of product or fragment ions derived from the ions in a mass or mass to charge ratio analyser 8 disposed downstream of the first device 5. The method further comprises obtaining a first set of drift times for the ions through the first device 5 by measuring ion arrival times and determining the transit time of the ions and/or of the product or fragment ions through one or more intermediate regions or devices 6, 7 disposed between the first device 5 and the mass to charge ratio analyser 8. The method further comprises obtaining a second set of drift times for the ions through the first device 5 by correcting the first set of drift times to account for the determined transit times.

    TWO DIMENSIONAL MSMS
    8.
    发明申请
    TWO DIMENSIONAL MSMS 审中-公开

    公开(公告)号：US20200321204A1

    公开(公告)日：2020-10-08

    申请号：US16910960

    申请日：2020-06-24

    Applicant: Micromass UK Limited

    Inventor： Keith Richardson ,  Jason Lee Wildgoose

    IPC: H01J49/00 ,  H01J49/02

    Abstract: A method of mass spectrometry is disclosed comprising: performing a plurality of cycles of operation during a single experimental run, wherein each cycle comprises: mass selectively transmitting precursor ions of a single mass, or range of masses, through or out of a mass separator or mass filter at any given time, wherein the mass separator or mass filter is operated such that the single mass or range of masses transmitted therefrom is varied with time; and mass analysing ions.

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