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1.ALKYNE PHOSPHORAMIDITES AND PREPARATION OF SPHERICAL NUCLEIC ACID CONSTRUCTS 审中-公开
Title translation: 碱性磷酸钙和球形核酸结构的制备公开(公告)号:US20160159834A1
公开(公告)日:2016-06-09
申请号:US14785867
申请日:2014-04-22
Applicant: NORTHWESTERN UNIVERSITY
Inventor: Andrew Lee , Chad A. Mirkin , Colin Michael Calabrese , Natalia Chernyak , Evelyn Auyeung
IPC: C07F9/24 , C12N15/113 , C07H19/10
CPC classification number: C07F9/2408 , A61K9/14 , A61K9/5115 , C07F9/2412 , C07F9/2458 , C07F9/65586 , C07H19/073 , C07H19/10 , C07H21/00 , C07H21/04 , C12N15/111 , C12N15/113 , C12N15/87 , C12N2310/3515 , C12N2310/3519
Abstract: The present disclosure is directed to compositions comprising alkyne oligonucleotides, nanoconjugates prepared from the same, and methods of their use.
Abstract translation: 本公开涉及包含炔烃寡核苷酸,由其制备的纳结合物及其使用方法的组合物。
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2.METAL-LIGAND COORDINATION POLYMER NANOPARTICLES AND METHODS FOR MAKING 有权
Title translation: 金属配位聚合物纳米颗粒及其制备方法公开(公告)号:US20160068839A1
公开(公告)日:2016-03-10
申请号:US14786569
申请日:2014-04-23
Applicant: NORTHWESTERN UNIVERSITY
Inventor: Chad A. Mirkin , Colin Michael Calabrese , William Morris
IPC: C12N15/113 , C12Q1/68 , C07F15/02 , C07F9/58
CPC classification number: C12N15/113 , A61K31/7052 , A61K31/7088 , B82Y5/00 , C07F9/58 , C07F15/02 , C07H21/00 , C12Q1/68 , G01N33/54346
Abstract: Disclosed herein are metal-ligand complexes containing polynucleotides, compounds for making the same, and methods of using the same.
Abstract translation: 本文公开了含有多核苷酸的金属 - 配体络合物,用于制备其的化合物及其使用方法。
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公开(公告)号:US09677075B2
公开(公告)日:2017-06-13
申请号:US14786569
申请日:2014-04-23
Applicant: NORTHWESTERN UNIVERSITY
Inventor: Chad A. Mirkin , Colin Michael Calabrese , William Morris
IPC: A01N43/04 , A61K31/70 , C12N15/113 , G01N33/543 , C07H21/00 , C07F9/58 , C07F15/02 , C12Q1/68 , A61K31/7052 , A61K31/7088 , B82Y5/00
CPC classification number: C12N15/113 , A61K31/7052 , A61K31/7088 , B82Y5/00 , C07F9/58 , C07F15/02 , C07H21/00 , C12Q1/68 , G01N33/54346
Abstract: Disclosed herein are metal-ligand complexes containing polynucleotides, compounds for making the same, and methods of using the same.
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公开(公告)号:US09617541B2
公开(公告)日:2017-04-11
申请号:US14831316
申请日:2015-08-20
Applicant: NORTHWESTERN UNIVERSITY
Inventor: Chad A. Mirkin , Colin Michael Calabrese , William E. Briley , Timothy J. Merkel
IPC: C12Q1/68 , C12N15/113 , C07D213/69 , C07F15/02 , C12N15/11 , B82Y5/00 , B82Y15/00
CPC classification number: C12N15/113 , B82Y5/00 , B82Y15/00 , C07D213/69 , C07F15/02 , C12N15/111 , C12N2310/11 , C12N2310/14 , C12N2310/351 , C12N2310/51 , C12N2320/32
Abstract: Disclosed herein are metal-ligand complexes containing polynucleotides, compounds for making the same, and methods of using the same.
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5.BIOCOMPATIBLE INFINITE COORDINATION POLYMER NANOPARTICLE -NUCLEIC ACID CONJUGATES FOR ANTISENSE GENE REGULATION 有权
Title translation: 生物成分无菌协调聚合物纳米颗粒酸抗凝抗原基因调控公开(公告)号:US20160053260A1
公开(公告)日:2016-02-25
申请号:US14831316
申请日:2015-08-20
Applicant: Northwestern University
Inventor: Chad A. Mirkin , Colin Michael Calabrese , William E. Briley , Timothy J. Merkel
IPC: C12N15/113 , C07F15/02 , C07D213/69
CPC classification number: C12N15/113 , B82Y5/00 , B82Y15/00 , C07D213/69 , C07F15/02 , C12N15/111 , C12N2310/11 , C12N2310/14 , C12N2310/351 , C12N2310/51 , C12N2320/32
Abstract: Disclosed herein are metal-ligand complexes containing polynucleotides, compounds for making the same, and methods of using the same.
Abstract translation: 本文公开了含有多核苷酸的金属 - 配体络合物,用于制备其的化合物及其使用方法。
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