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公开(公告)号：US12144579B2
公开(公告)日：2024-11-19
申请号：US17043161
申请日：2019-03-29
Applicant: NORTHWESTERN UNIVERSITY
Inventor： John A. Rogers , Shuai Xu , Yajing Li , Philipp Gutruf , Surabhi R. Madhvapathy , Siddharth Krishnan
Abstract: Provided are wireless electronic devices for thermally interfacing with a biological tissue. The device may have a flexible substrate; a thermal actuator supported by said flexible substrate configured to provide a thermal input to said biological tissue; a temperature sensor supported by said flexible substrate configured to measure a temperature to determine thermal conductivity of said biological tissue; and a wireless electronic system in electronic communication with said thermal actuator and said temperature sensor, wherein said wireless electronic system is configured to provide two-way communication with an external controller. Also provided are related methods of using the electronic devices, including for cosmetic, beauty, or medical applications.
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公开(公告)号：US20240382097A1
公开(公告)日：2024-11-21
申请号：US18691924
申请日：2022-09-15
Applicant: NORTHWESTERN UNIVERSITY
Inventor： Sung Soo Kwak , Shuai Xu , Ha UK Chung , Hyoyoung Jeong , John A. Rogers
IPC: A61B5/0205 , A61B5/00 , A61B5/01 , A61B5/02 , A61B5/021 , A61B5/024 , A61B5/08 , A61B5/113 , A61B5/145 , A61B5/257 , A61B5/263 , A61B5/28 , A61B5/296
Abstract: This invention relates to apparatuses and methods for non-invasively measuring physiological parameters of a mammal subject using easily removable flexible electronics, and applications of the same. Specifically, a novel sensor class with a pre-curved architecture and strategically located perforations that may be used in apparatuses and methods for measuring physiological parameters of a mammal subject. Further, adhesive layers are used to attach the sensor systems on the skin of the mammal subject, and each adhesive layer is switchable chemically or physically between an adhesive state and a non-adhesive state, allowing easy removal of the corresponding sensor system from the skin of the mammal subject when being switched to the non-adhesive state.
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公开(公告)号：US11874965B2
公开(公告)日：2024-01-16
申请号：US17466094
申请日：2021-09-03
Inventor： John A. Rogers , Shuai Xu , In Hwa Jung , Ha Uk Chung , Xinge Yu , Yu Yang , Jungyup Lee , Rujie Sun
CPC classification number: G06F3/015 , G06F1/163 , G06F3/016 , G06T19/006 , H04W4/80
Abstract: Provided are actuation devices, virtual reality devices formed from the actuation devices, and related virtual reality methods. The devices may comprise a plurality of spatially distributed actuators, each actuator configured for interacting with a biological skin surface; a wireless controller configured to receive operative command signals to control each of the actuators; and a wireless power system to power the actuators. Also provided are unique layouts of multiple interconnected devices to achieve large area coverage.
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公开(公告)号：US11112869B2
公开(公告)日：2021-09-07
申请号：US16481209
申请日：2018-01-26
Inventor： John A. Rogers , Shuai Xu , In Hwa Jung , Ha Uk Chung , Xinge Yu , Yu Yang , Jungyup Lee , Rujie Sun
Abstract: Provided are actuation devices, virtual reality devices formed from the actuation devices, and related virtual reality methods. The devices may comprise a plurality of spatially distributed actuators, each actuator configured for interacting with a biological skin surface; a wireless controller configured to receive operative command signals to control each of the actuators; and a wireless power system to power the actuators. Also provided are unique layouts of multiple interconnected devices to achieve large area coverage.
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公开(公告)号：US20240358259A1
公开(公告)日：2024-10-31
申请号：US18285271
申请日：2022-04-05
Inventor： Keum San Chun , Jong Yoon Lee , Youn Joung Kang , Hyoyoung Jeong , John A. Rogers , Shuai Xu
CPC classification number: A61B5/0093 , A61B5/1126 , A61B5/6824 , A61B5/6826 , A61B5/6832 , A61B5/725 , A61B5/7257 , A61B5/7267 , A61B5/7405 , A61B5/742 , A61B5/7455 , A61B2560/0209 , A61B2560/0214 , A61B2560/045 , A61B2560/0462 , A61B2562/0219 , A61B2562/14 , A61B2562/164 , A61B2562/166 , A61B2562/225
Abstract: This invention in one aspect relates to an acousto-mechanic sensor includes at least one inertial measurement unit (IMU) for operably detecting vibratory and motion signatures of physiological processes; and a plurality of electronic components comprising a microcontroller unit coupled to the at least one IMU for receiving data from the at least one IU and processing the received data, and a wireless communication system for wireless data transmission. The novel acousto-mechanic sensor has broad applications ranging from the assessing the efficacy of drugs for conditions that cause itch to monitoring disease severity and treatment response.
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Patent Agency Ranking
公开(公告)号：US20240000322A1
公开(公告)日：2024-01-04
申请号：US18034893
申请日：2021-11-02
Applicant: NORTHWESTERN UNIVERSITY
Inventor： Shuai Xu , Hyoyoung Jeong , Jong Yoon Lee , Kun Hyuck Lee , John A. Rogers
IPC: A61B5/0205 , A61B5/113 , A61B5/00
CPC classification number: A61B5/02055 , A61B5/1135 , A61B5/7214 , A61B2562/0219 , A61B5/6832 , A61B5/4803 , A61B5/4205
Abstract: This invention discloses an electronic device for measuring physiological parameters of a living subject including at least a first inertial measurement unit (IMU) and a second IMU, the first IMU and the second IMU are time-synchronized to and spatially and mechanically separated from each other; and a microcontroller unit (MCU) electronically coupled to the first IMU and the second IMU for processing of data streams from the first IMU and the second IMU.
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公开(公告)号：US11571586B2
公开(公告)日：2023-02-07
申请号：US17056094
申请日：2019-05-17
Applicant: NORTHWESTERN UNIVERSITY
Inventor： Shuai Xu , Chenkai Xu , Hao Zhang , Hangbo Zhao , John A. Rogers
Abstract: Provided are conformable light delivery devices for increasing light penetration depth and related methods. The device may comprise a microarray of tissue penetrating members, each member having a distal end and a proximal end, wherein the tissue penetrating members are at least partially optically transparent to provide optical transmission through a surface that extends between the distal and proximal ends of each tissue penetrating member and a substrate that supports the tissue penetrating members, wherein the substrate is optionally a flexible substrate.
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公开(公告)号：US11896840B2
公开(公告)日：2024-02-13
申请号：US18060073
申请日：2022-11-30
Applicant: NORTHWESTERN UNIVERSITY
Inventor： Shuai Xu , Chenkai Xu , Hao Zhang , Hangbo Zhao , John A. Rogers
CPC classification number: A61N5/0601 , A61M37/0015 , A61N5/062 , A61M2037/003 , A61M2037/0061 , A61N2005/0602 , A61N2005/063 , A61N2005/0652 , A61N2005/0661
Abstract: Provided are conformable light delivery devices for increasing light penetration depth and related methods. The device comprises a tissue penetrating member having a distal end and a proximal end, the tissue penetrating member configured to penetrate the tissue of the patient to be inserted into the tissue, wherein the tissue penetrating member is at least partially optically transparent along a surface of the tissue penetrating member positioned between the distal end of the tissue penetrating member and the proximal end of the tissue penetrating member to provide optical transmission of at least a portion of the light through the surface of the tissue penetrating member, thereby allowing at least the portion of the light to be delivered into the tissue of the patient when the tissue penetrating member is inserted into the tissue; and a substrate that supports the tissue penetrating member.
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公开(公告)号：US20240023882A1
公开(公告)日：2024-01-25
申请号：US18031389
申请日：2021-10-18
Applicant: NORTHWESTERN UNIVERSITY
Inventor： John A. Rogers , Anthony R. Banks , Surabhi Rao Madhvapathy , Heling Wang , Yonggang Huang , Shuai Xu
CPC classification number: A61B5/443 , A61B5/4875 , A61B5/6832 , A61B5/14521 , A61B5/002 , G01N25/56 , A61B2562/164 , A61B2562/166 , A61B2562/0271
Abstract: This invention relates to a soft, battery-free, flexible, non-invasive, reusable hydration sensor adherable to even small-areas and curvilinear surfaces of a body. The hydration sensor measures volumetric water content in skin as a function of depth, and wirelessly transmits data to a portable smart device. The hydration sensor includes a top layer for thermal, chemical and mechanical isolation of the hydration sensor from an environment; a bottom layer operably placed on a target area of interest on the skin; and a flexible printed circuit board (f-PCB) disposed between the top layer and the bottom layer. The f-PCB contains electronics for sensing and wireless communication. The bottom layer operably serves as a direct interface between the f-PCB and the skin and comprises a flexible adhesive for attaching the hydration sensor to the skin.
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公开(公告)号：US11666240B2
公开(公告)日：2023-06-06
申请号：US17417180
申请日：2020-01-03
Applicant: NORTHWESTERN UNIVERSITY
Inventor： John A. Rogers , Shuai Xu , Seung Yun Heo , Kyeongha Kwon , Jong Yoon Lee
IPC: A61B5/05 , A61B5/318 , A61B5/389 , A61B5/00 , A61B5/0205 , A61B5/145 , A61B5/1455 , G01J1/44 , H04Q9/00
CPC classification number: A61B5/05 , A61B5/002 , A61B5/0006 , A61B5/0022 , A61B5/02055 , A61B5/14517 , A61B5/14552 , A61B5/318 , A61B5/389 , A61B5/681 , A61B5/6804 , A61B5/742 , A61B5/746 , A61B5/7455 , G01J1/44 , H04Q9/00 , A61B2560/0242 , A61B2562/0204 , A61B2562/029 , A61B2562/0219 , A61B2562/0247 , A61B2562/0271 , G01J2001/446 , H04Q2209/43 , H04Q2209/826
Abstract: An electronic system for monitoring a physical parameter includes an ADM comprising an accumulation mode sensor for measuring the physical parameter by generating electrical energy associated with the physical parameter in response to a surrounding condition, and an energy storing device coupled to the accumulation mode sensor for accumulatively storing the generated electrical energy; a power source; and an SoC coupling with the ADM and the power source, configured such that the stored electrical energy is monitored, and when the stored electrical energy is equal to or greater than a pre-defined threshold, a wake-up event is generated to trigger the SoC to operates in a run mode in which the physical parameter is wirelessly transmitted to a receiver and the stored electrical energy in the energy storing device is discharged, and then the SoC returns to a sleep mode in which a minimal power is consumed.
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