公开(公告)号：US20180104388A1

公开(公告)日：2018-04-19

申请号：US15784881

申请日：2017-10-16

Applicant: Novartis AG

Inventor： Andrew Mason Hahn ,  Andrew David Johnson ,  Brian William McDonell

IPC: A61M1/00

Abstract: A method and system assist a physician in controlling pressure in a line during a surgery. The method includes filtering a vacuum signal such that portions of the vacuum signal having a frequency greater than a threshold frequency (e.g., ten Hz) are not passed. Thus a filtered vacuum signal is provided. The method also includes providing a control signal to a vacuum source. The control signal is selected from the vacuum signal and the filtered vacuum signal. The vacuum source provides a vacuum having a level based on the control signal.

公开(公告)号：US11051978B2

公开(公告)日：2021-07-06

申请号：US15590084

申请日：2017-05-09

Applicant: Novartis AG

Inventor： Tammo Heeren ,  Andrew David Johnson

IPC: A61F9/007 ,  A61M3/02 ,  A61M1/00

Abstract: Ophthalmic surgical devices, systems, and methods for regulating aspiration from a patient's eye are provided. A vacuum pump in fluid communication with an aspiration line provides fluid aspiration from a vitreous chamber of the eye through the aspiration line. A sensor disposed adjacent to or inside the eye determines sensor data relating to an intraocular pressure (IOP). The controller receives the sensor data and regulates the aspiration in response to changes in the IOP, such as by controlling the vacuum pump. The controller may determine whether a fluid infusion to the vitreous chamber through an infusion line is below a maximum infusion level, regulate the infusion in response to the IOP being below a threshold value and the infusion being below the maximum infusion level, and regulate the aspiration in response to the IOP being below the threshold value and the infusion being at or above the maximum infusion level.

公开(公告)号：US10722618B2

公开(公告)日：2020-07-28

申请号：US15784881

申请日：2017-10-16

Applicant: Novartis AG

Inventor： Andrew Mason Hahn ,  Andrew David Johnson ,  Brian William McDonell

IPC: A61M1/00 ,  A61F9/007

Abstract: A method and system assist a physician in controlling pressure in a line during a surgery. The method includes filtering a vacuum signal such that portions of the vacuum signal having a frequency greater than a threshold frequency (e.g., ten Hz) are not passed. Thus a filtered vacuum signal is provided. The method also includes providing a control signal to a vacuum source. The control signal is selected from the vacuum signal and the filtered vacuum signal. The vacuum source provides a vacuum having a level based on the control signal.

公开(公告)号：US20180140373A1

公开(公告)日：2018-05-24

申请号：US15793555

申请日：2017-10-25

Applicant: Novartis AG

Inventor： Cesario Dos Santos ,  Andrew David Johnson ,  Ronald Smith ,  Gerald David Bacher ,  Alireza Mirsepassi ,  Ryan Takakawa

IPC: A61B90/30

Abstract: The present disclosure provides a vitreous visualization system including a vitreous illuminator including a vitreous visualization light source and a vitreous visualization tool that transmits lights from the vitreous visualization light source into an eye having vitreous, a pupil, and a vitreous-pupil axis. The vitreous visualization system further includes a general illuminator, which may include a general light source and a general illumination tool that transmits light from the general light source into the eye. The present disclosure further provided a vitreous visualization system including only a vitreous illuminator that transmits light from the vitreous visualization light source into an eye having vitreous, a pupil, a vitreous-pupil axis, and a retina at an angle B with the vitreous-pupil axis of the eye such that the brightness of vitreous in the eye is higher than the brightness of the retina of the eye.

公开(公告)号：US09839749B2

公开(公告)日：2017-12-12

申请号：US15139799

申请日：2016-04-27

Applicant: Novartis AG

Inventor： Andrew David Johnson ,  Pooria Sharif Kashani

IPC: A61B1/06 ,  A61M5/172 ,  A61F9/007 ,  A61B1/07 ,  A61M3/02 ,  A61M1/00 ,  A61B3/16

CPC classification number: A61M5/1723 ,  A61B1/07 ,  A61B3/16 ,  A61F9/007 ,  A61F9/00736 ,  A61M1/0031 ,  A61M3/0279 ,  A61M2205/3344

Abstract: An ophthalmic surgical system enabling pressure measurements proximal to the eye may include an illumination probe having a probe tip configured for insertion through an incision in an eye of a patient. The probe tip may include a distal end of an optical fiber, wherein the distal end of the optical fiber includes a first reflective surface and a second reflective surface. The first and second reflective surfaces being separated by a cavity, wherein the second reflective surface is provided by a partially transparent wall forming an exterior surface of the distal end of the optical fiber.

公开(公告)号：US20170312431A1

公开(公告)日：2017-11-02

申请号：US15139799

申请日：2016-04-27

Applicant: Novartis AG

Inventor： Andrew David Johnson ,  Pooria Sharif Kashani

IPC: A61M5/172 ,  A61M3/02 ,  A61B3/16 ,  A61B1/07 ,  A61F9/007 ,  A61M1/00

CPC classification number: A61M5/1723 ,  A61B1/07 ,  A61B3/16 ,  A61F9/007 ,  A61F9/00736 ,  A61M1/0031 ,  A61M3/0279 ,  A61M2205/3344

Abstract: An ophthalmic surgical system enabling pressure measurements proximal to the eye may include an illumination probe having a probe tip configured for insertion through an incision in an eye of a patient. The probe tip may include a distal end of an optical fiber, wherein the distal end of the optical fiber includes a first reflective surface and a second reflective surface. The first and second reflective surfaces being separated by a cavity, wherein the second reflective surface is provided by a partially transparent wall forming an exterior surface of the distal end of the optical fiber.

公开(公告)号：US11432961B2

公开(公告)日：2022-09-06

申请号：US15591498

申请日：2017-05-10

Applicant: Novartis AG

Inventor： Tammo Heeren ,  Andrew David Johnson

IPC: A61F9/00 ,  A61F9/007 ,  A61M5/142 ,  A61M5/168 ,  A61B3/16 ,  A61M5/172

Abstract: Ophthalmic surgical devices, systems, and methods for automatically controlling the injection or extraction of viscous fluids from a patient's eye are provided. A syringe pump connected with an actuation line and a powered syringe provides pressures for viscous fluid injection or extraction in a vitreous chamber of the eye. A sensor disposed adjacent to or inside the eye determines sensor data relating to an intraocular pressure (IOP). The controller receives the sensor data and regulates the injection or extraction of the viscous fluid in response to the detected IOP, such as by controlling the syringe pump. The controller may determine whether the IOP is above an upper threshold or below a lower threshold and may control the syringe pump to regulate the injection or extraction of viscous fluid to maintain the IOP between the upper and the lower thresholds.

公开(公告)号：US20180271643A1

公开(公告)日：2018-09-27

申请号：US15928311

申请日：2018-03-22

Applicant: Novartis AG

Inventor： Nicholas Max Gunn ,  Andrew David Johnson

IPC: A61F2/14 ,  A61L31/14 ,  A61L31/04 ,  A61L31/06 ,  A61F9/00 ,  A61F9/007

CPC classification number: A61F2/14 ,  A61F9/0017 ,  A61F9/00781 ,  A61F2002/0081 ,  A61F2210/0004 ,  A61F2220/0008 ,  A61F2220/005 ,  A61F2230/0006 ,  A61L31/022 ,  A61L31/04 ,  A61L31/046 ,  A61L31/048 ,  A61L31/06 ,  A61L31/145 ,  A61L31/148 ,  A61L2430/16 ,  A61L2430/32

Abstract: Ophthalmic implants and methods of use that provide structural support to the optic nerve are disclosed herein. An adhesive and/or ophthalmic implant may be delivered to an optic nerve of an eye to relieve pressure on the optic nerve. The ophthalmic implant may include a base portion that includes a first surface and a second surface opposing the second surface and a protrusion from the second surface for extending into a cup of an optic nerve in an eye.

公开(公告)号：US10052193B2

公开(公告)日：2018-08-21

申请号：US15238330

申请日：2016-08-16

Applicant: Novartis AG

Inventor： Andrew David Johnson

IPC: A61F2/14 ,  A61F9/007 ,  A61F9/00 ,  A61F9/008 ,  A61M27/00

CPC classification number: A61F2/142 ,  A61F9/0017 ,  A61F9/00781 ,  A61F2009/00891 ,  A61M27/002

Abstract: A method includes forming a conjunctival incision in a patient's eye, attaching a synthetic flap to the patient's eye within the conjunctival incision, forming a scleral tunnel underneath the synthetic flap, the scleral tunnel extending from an exterior of a sclera to an anterior chamber of the patient's eye, and closing the conjunctival incision.

公开(公告)号：US20180049864A1

公开(公告)日：2018-02-22

申请号：US15237944

申请日：2016-08-16

Applicant: Novartis AG

Inventor： Andrew David Johnson

IPC: A61F2/14

CPC classification number: A61F2/142 ,  A61F2/15 ,  A61F9/00781 ,  A61F2220/0016 ,  A61F2250/0012

Abstract: Described herein is an extension device to extend ocular tissue within an irideocorneal angle of an eye of a patient, comprising a flexible body and a plurality of tensioning features disposed on the body. The body is sized and configured to be disposed within the irideocorneal angle. The body has a curved longitudinal axis, a channel extending from a first end to a second end, an inner convex side, and an outer concave side. The body is flexible between a first flexed condition and a second unflexed condition. The body has a first radius of curvature in the first flexed condition and a second radius of curvature in the unflexed condition. Each tensioning feature is shaped and sized to grasp the ocular tissue within the irideocorneal angle.