公开(公告)号：US20240360426A1

公开(公告)日：2024-10-31

申请号：US18675391

申请日：2024-05-28

Applicant: Novozymes A/S

Inventor： Hengxiao Zhai ,  Jesper Vind ,  Lars Kobberoe Skov ,  Qian Zhang ,  Ester Santigosa ,  Jose-Otavio B. Sorbara ,  Aurelia Anne Catherine Charlotte Seon ,  Carrie Louise Walk

IPC: C12N9/16 ,  A23K10/14 ,  A23K20/174 ,  A23K20/189 ,  A23K20/20 ,  C12N15/75

CPC classification number: C12N9/16 ,  A23K10/14 ,  A23K20/174 ,  A23K20/189 ,  A23K20/30 ,  C12N15/75 ,  C12Y301/03008

Abstract: Methods of producing phytase variants useful for liberating phosphorous from phytate substrates, for reducing phytate levels in animal manure, for treating vegetable proteins, for improving the nutritional value of animal feed, for improving nutrient retention and/or digestibility in an animal, and for increasing weight gain, improving specific growth rate and/or improving Feed Conversion Ratio of an animal.

公开(公告)号：US12037613B2

公开(公告)日：2024-07-16

申请号：US17402099

申请日：2021-08-13

Applicant: Novozymes A/S

Inventor： Hengxiao Zhai ,  Jesper Vind ,  Lars Kobberoe Skov ,  Qian Zhang ,  Ester Santigosa ,  Jose-Otavio B. Sorbara ,  Aurelia Anne Catherine Charlotte Seon ,  Carrie Louise Walk

IPC: C12N9/16 ,  A23K10/14 ,  A23K20/174 ,  A23K20/189 ,  A23K20/20 ,  C12N15/75

CPC classification number: C12N9/16 ,  A23K10/14 ,  A23K20/174 ,  A23K20/189 ,  A23K20/30 ,  C12N15/75 ,  C12Y301/03008

Abstract: The present invention relates to phytase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US20230365948A1

公开(公告)日：2023-11-16

申请号：US18337172

申请日：2023-06-19

Applicant: Novozymes A/S

Inventor： Allan Svendsen ,  Sune Fang Christensen ,  Lars Lehman Hylling Christensen ,  Vikram Kjoller Bhatia ,  Jesper Vind ,  Vibeke Skovsgaard Nielsen

IPC: C12N9/20 ,  C11D11/00 ,  C11D1/83 ,  C11D3/386 ,  C11D1/14 ,  C11D1/72 ,  C11D1/22

CPC classification number: C12N9/20 ,  C12Y301/01003 ,  C11D11/0017 ,  C11D1/83 ,  C11D3/38627 ,  C11D1/146 ,  C11D1/72 ,  C11D1/22

Abstract: The present invention relates to a variant of a parent lipase, wherein said variant has at least 60% but less than 100% sequence identity with SEQ ID NO: 2; has lipase activity; has substitutions corresponding to G91A and N92D in the lid region located from position G82 to position I100 of SEQ ID NO: 2; has one or more additional substitutions in the lid region; and has at least mutations in positions corresponding to position T231 and position N233 of SEQ ID NO: 2. The present invention also relates to compositions, methods for cleaning a surface using a variant or a composition of the invention; polynucleotides encoding the variants; nucleic acid constructs, vectors, host cells comprising the polynucleotides; methods of using the variants; and methods for obtaining the lipase variant.

公开(公告)号：US11078445B2

公开(公告)日：2021-08-03

申请号：US16608694

申请日：2018-05-04

Applicant: Novozymes A/S

Inventor： Jesper Vind ,  Thomas A. Poulsen ,  Miguel D G P Toscano

IPC: C12N9/20 ,  C11D3/386 ,  C11D3/04 ,  C11D11/00

Abstract: The present invention relates to a composition comprising: (a) a source of sulfite; and (b) a lipase variant of a parent lipase, wherein one or more amino acids in the parent lipase within 20 angstrom (Å) of a cysteine bridge are replaced with a more negatively charged amino acid.

公开(公告)号：US10669511B2

公开(公告)日：2020-06-02

申请号：US15533435

申请日：2015-12-18

Applicant: Novozymes A/S

Inventor： Kim Borch ,  Jesper Vind

IPC: C12N15/00 ,  C12N1/20 ,  C07H21/04 ,  C11D3/386 ,  C12N9/20

Abstract: The present invention relates to detergent compositions comprising lipase variants. The present invention also relates to lipase variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US20190390182A1

公开(公告)日：2019-12-26

申请号：US16540180

申请日：2019-08-14

Applicant: NOVOZYMES A/S

Inventor： Rakhi Saikia ,  Geetha Hiremath Mendez ,  Sohel Dalal ,  Padmavathi Balumuri ,  Santhosh Vasu Mepadam ,  Lone Baunsgaard ,  Jesper Vind ,  Garry Paul Gippert ,  Kim Borch

IPC: C12N9/20 ,  C11D3/386

Abstract: The present invention relates to a lipase variant of a parent lipase, which variant has lipase activity, at least 75% but less than 100% sequence identity to SEQ ID NO: 3 and comprises a substitution at one or more positions corresponding to positions 1; 2; 3; 4; 5; 6; 7; 9; 10; 11; 12; 13; 14; 15; 17; 18; 29; 30; 33; 34; 36; 37; 38; 40; 41; 43; 44; 45; 46; 47; 49; 50; 51; 52; 54; 55; 57; 58; 59; 60; 69; 70; 71; 72; 81; 82; 85; 86; 87; 89; 90; 91; 92; 94; 95; 96; 97; 99; 100; 101; 102; 103; 105; 108; 111; 115; 116; 118; 119; 120; 122; 123; 124; 126; 127; 128; 129; 130; 131; 132; 133; 134; 136; 144; 152; 155; 157; 158; 159; 161; 162; 163; 177; 178; 181; 182; 184; 185; 187; 189; 191; 196; 197; 199; 203; 205; 206; 207; 208; 209; 211; 215; 220; 221; 222; 223; 224; 226; 229; 230; 232; 235; 236; 240; 242; 243; 244; 247; 248; 252; 254; 255; 257; 260; 261; 262 of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US20190292531A1

公开(公告)日：2019-09-26

申请号：US16316458

申请日：2017-07-14

Applicant: NOVOZYMES A/S

Inventor： Miguel Duarte Guilherme Toscano ,  Allan Svendsen ,  Jesper Vind ,  Alexander David Fulton ,  Lone Baunsgaard

IPC: C12N9/20 ,  C11D3/386

Abstract: The present invention relates to lipase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US10119128B2

公开(公告)日：2018-11-06

申请号：US15177879

申请日：2016-06-09

Applicant: NOVOZYMES A/S

Inventor： Luise Erlandsen ,  Carsten Hoerslev Hansen ,  Jesper Vind ,  Allan Svendsen ,  Carsten Peter Sonksen

IPC: C12N9/20 ,  C12N9/18 ,  C11D3/42 ,  C11D3/386 ,  C11D3/39

Abstract: The present invention relates to lipase variants and methods of obtaining them. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US20180094252A1

公开(公告)日：2018-04-05

申请号：US15842247

申请日：2017-12-14

Applicant: NOVOZYMES A/S

Inventor： Jesper Vind ,  Esben Peter Friis ,  Thomas Agsersten Poulsen ,  Michael Skjøt ,  Peter Kamp Hansen ,  Frank Winther Rasmussen ,  Steen Krogsgaard ,  Joyce Craig ,  Guillermo Coward-Kelly ,  Keiichi Ayabe

IPC: C12N9/34 ,  C12N15/52 ,  C12P19/24 ,  C12P7/10 ,  C12N9/30 ,  C12P19/02

CPC classification number: C12N9/2428 ,  C12N9/242 ,  C12N15/52 ,  C12P7/10 ,  C12P19/02 ,  C12P19/24 ,  Y02E50/16

Abstract: The present invention relates to variants of a parent glucoamylase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the glucoamylase variants.

公开(公告)号：US20170306269A1

公开(公告)日：2017-10-26

申请号：US15513435

申请日：2015-09-28

Applicant: Novozymes A/S

Inventor： Carsten Hoerslev Hansen ,  Jesper Vind ,  Luise Erlandsen ,  Bitten Plesner ,  Anna Catharina Olsen Stenholm

IPC: C11D3/386 ,  C12N9/20 ,  C12N9/16 ,  C11D3/39 ,  C12N9/00

CPC classification number: C11D3/386 ,  C11D3/38627 ,  C11D3/38681 ,  C11D3/392 ,  C12N9/00 ,  C12N9/16 ,  C12N9/20 ,  C12Y301/00

Abstract: The present invention relates to lipase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.