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公开(公告)号：US20200254219A1
公开(公告)日：2020-08-13
申请号：US16861633
申请日：2020-04-29
Applicant: Nextern, Inc.
Inventor： Ryan Douglas , Richard Farrell , Dennis Berke , Davis Flanagan , David Bontrager , Brian Loushine
IPC: A61M25/01
Abstract: Apparatus and associated methods relate to a catheter manipulation handle with user interface controls for steering a catheter in situ while providing an augmented (e.g., motorized, powered and tunable precision steering, and perforation safeguards) control and feedback user experience. In an illustrative example, the catheter manipulation handle may provide motor assisted operation to automatically rotate and/or deflect a distal tip of the catheter to steer and guide the distal tip to a target location in the patient's vasculature system. The augmented feedback may include, for example, haptic feedback via the handle. Haptic, audible, and/or visual feedback via the handle may indicate, for example, proximity or engagement of the distal tip with sensitive tissue. In some examples, the handle's augmented operation may advantageously amplify feedback signals to enhance the user's perception of the patient's safety with respect to the safe passage of the distal tip through the patient's vasculature.
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Patent Agency Ranking
公开(公告)号：US11285471B2
公开(公告)日：2022-03-29
申请号：US15993481
申请日：2018-05-30
Applicant: Nextern, Inc.
Inventor： Ryan Douglas , Richard Farrell , David Bontrager
Abstract: Apparatus and associated methods relate to an adaptable microenvironment for cellular and biological processing in a traceable, transportable unit. In an illustrative example, an apparatus consists of one or more portable cell tissue containment modules that may be removably interconnected to perform a processing step and/or transfer the stored medium to another module. Associated apparatus and methods are proposed to ensure non-contaminating mechanical or fluid communication between a plurality of modules or between a module and peripheral equipment, to limit process errors such as steps performed out of order, and to intrinsically manage identification of tissue samples with accompanying process data in a manner that decreases risk of mislabeling or otherwise mishandling a sample at all stages of the production and treatment process.
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公开(公告)号：US11717644B2
公开(公告)日：2023-08-08
申请号：US16861633
申请日：2020-04-29
Applicant: Nextern, Inc.
Inventor： Ryan Douglas , Richard Farrell , Dennis Berke , Davis Flanagan , David Bontrager , Brian Loushine
IPC: A61M25/01
CPC classification number: A61M25/0136 , A61M25/0113 , A61M2025/0166 , A61M2205/332 , A61M2205/3331 , A61M2205/3379
Abstract: Apparatus and associated methods relate to a catheter manipulation handle with user interface controls for steering a catheter in situ while providing an augmented (e.g., motorized, powered and tunable precision steering, and perforation safeguards) control and feedback user experience. In an illustrative example, the catheter manipulation handle may provide motor assisted operation to automatically rotate and/or deflect a distal tip of the catheter to steer and guide the distal tip to a target location in the patient's vasculature system. The augmented feedback may include, for example, haptic feedback via the handle. Haptic, audible, and/or visual feedback via the handle may indicate, for example, proximity or engagement of the distal tip with sensitive tissue. In some examples, the handle's augmented operation may advantageously amplify feedback signals to enhance the user's perception of the patient's safety with respect to the safe passage of the distal tip through the patient's vasculature.
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公开(公告)号：US20180369802A1
公开(公告)日：2018-12-27
申请号：US15993481
申请日：2018-05-30
Applicant: Nextern, Inc.
Inventor： Ryan Douglas , Richard Farrell , David Bontrager
Abstract: Apparatus and associated methods relate to an adaptable microenvironment for cellular and biological processing in a traceable, transportable unit. In an illustrative example, an apparatus consists of one or more portable cell tissue containment modules that may be removably interconnected to perform a processing step and/or transfer the stored medium to another module. Associated apparatus and methods are proposed to ensure non-contaminating mechanical or fluid communication between a plurality of modules or between a module and peripheral equipment, to limit process errors such as steps performed out of order, and to intrinsically manage identification of tissue samples with accompanying process data in a manner that decreases risk of mislabeling or otherwise mishandling a sample at all stages of the production and treatment process.
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公开(公告)号：US11124754B2
公开(公告)日：2021-09-21
申请号：US15993472
申请日：2018-05-30
Applicant: Nextern, Inc.
Inventor： Ryan Douglas , Richard Farrell , David Bontrager
Abstract: Apparatus and associated methods relate to an optimizable cellular growth chamber, where growth conditions are optimized by adjusting gas pressures through a gas permeable membrane. In an illustrative example, an apparatus may provide a volume to contain growth medium and the cells under propagation, where the volume has limited but non-zero pneumatic communication with a pressure-controlled chamber via a gas-permeable membrane. Associated apparatus and methods are proposed to manage desired growth conditions via deliberate control of parameters, such as partial pressures, for example.
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公开(公告)号：US20190002816A1
公开(公告)日：2019-01-03
申请号：US15993472
申请日：2018-05-30
Applicant: Nextern, Inc.
Inventor： Ryan Douglas , Richard Farrell , David Bontrager
IPC: C12M1/34
Abstract: Apparatus and associated methods relate to an optimizable cellular growth chamber, where growth conditions are optimized by adjusting gas pressures through a gas permeable membrane. In an illustrative example, an apparatus may provide a volume to contain growth medium and the cells under propagation, where the volume has limited but non-zero pneumatic communication with a pressure-controlled chamber via a gas-permeable membrane. Associated apparatus and methods are proposed to manage desired growth conditions via deliberate control of parameters, such as partial pressures, for example.
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