Polypeptides With Lipase Activity and Polynucleotides Encoding Same
    7.
    发明申请
    Polypeptides With Lipase Activity and Polynucleotides Encoding Same 有权
    具有脂肪酶活性的多肽和编码相同的多核苷酸

    公开(公告)号:US20160010038A1

    公开(公告)日:2016-01-14

    申请号:US14770006

    申请日:2014-03-19

    Applicant: NOVOZYMES A/S

    CPC classification number: C11D3/38627 C11D3/38681 C12N9/20 C12P13/008

    Abstract: The present invention relates to isolated polypeptides with lipase activity, selected from the group consisting of: (a) a polypeptide having at least 75%, at least 80%, at least 85%, at least 90%, at least 91%, at least 92%, at least 93%, at least 94%, at least 95%, at least 96%, at least 97%, at least 98%, at least 99%, or 100% sequence identity to SEQ ID NO: 4; (b) a polypeptide encoded by a polynucleotide that hybridizes under low stringency conditions, medium stringency conditions, medium-high stringency conditions, high stringency conditions, or very high stringency conditions with (i) SEQ ID NO: 3 or the full-length complement of (i); (c) a polypeptide encoded by a polynucleotide having at least 75%, at least 80%, at least 85%, at least 90%, at least 91%, at least 92%, at least 93%, at least 94%, at least 95%, at least 96%, at least 97%, at least 98%, at least 99%, or 100% sequence identity to SEQ ID NO: 3; (d) a polypeptide which is a variant of SEQ ID NO: 4 comprising a substitution, deletion, and/or insertion at one or more (e.g. several) positions; and (e) a polypeptide which is a fragment of any of the polypeptides of (a), (b), (c) or (d). The invention also relates to polynucleotides encoding the polypeptides; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the polypeptides.

    Abstract translation: 本发明涉及具有脂肪酶活性的分离的多肽,其选自:(a)多肽,其具有至少75%,至少80%,至少85%,至少90%,至少91%,在 与SEQ ID NO:4的至少92%,至少93%,至少94%,至少95%,至少96%,至少97%,至少98%,至少99%或100%的序列同一性 ; (b)由多核苷酸编码的多肽,其在低严格条件,中等严格条件,中等严格条件,高严格条件或非常高严格条件下与(i)SEQ ID NO:3或全长补体 的(i); (c)由多核苷酸编码的多肽,所述多核苷酸具有至少75%,至少80%,至少85%,至少90%,至少91%,至少92%,至少93%,至少94% 与SEQ ID NO:3的至少95%,至少96%,至少97%,至少98%,至少99%或100%的序列同一性; (d)在一个或多个(例如数个)位置上包含取代,缺失和/或插入的SEQ ID NO:4的变体的多肽; 和(e)作为(a),(b),(c)或(d)的多肽的片段的多肽。 本发明还涉及编码多肽的多核苷酸; 核酸构建体,载体和包含多核苷酸的宿主细胞; 和使用多肽的方法。

    Particulate Composition
    8.
    发明申请

    公开(公告)号:US20250136897A1

    公开(公告)日:2025-05-01

    申请号:US18949676

    申请日:2024-11-15

    Applicant: Novozymes A/S

    Abstract: Enzymes tend to be inactivated during wash by a bleach catalyst in combination with a source of organic peroxyacids. The risk of enzyme inactivation by active bleach catalyst is reduced when the release of the enzyme into the wash solution is delayed. The enzyme stability during washing together with a bleach catalyst can be improved by applying a delayed-release coating to cores which comprise the enzyme.

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