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公开(公告)号:US10568556B2
公开(公告)日:2020-02-25
申请号:US15888918
申请日:2018-02-05
Applicant: OptiScan Biomedical Corporation
Inventor: Jennifer H. Gable , James R. Braig , Kenneth I. Li , Mark Wechsler , Peng Zheng , Richard Keenan
IPC: A61B5/157 , A61B5/00 , A61B5/145 , A61M5/172 , A61B5/15 , A61B5/153 , A61B5/155 , A61B5/1455 , A61B10/00 , G01N21/3577 , A61M5/142 , A61M5/168 , A61M5/36 , A61M5/38 , G01N21/03 , G01N21/35
Abstract: Disclosed is an apparatus for analyzing the composition of bodily fluid. The apparatus can include a fluid handling network including a patient end configured to maintain fluid communication with a bodily fluid in a patient and a pump unit in operative engagement with the fluid handling network. The pump unit can have an infusion mode, in which the pump unit is operable to deliver infusion fluid to the patient through the patient end, and a sample draw mode, in which the pump unit is operable to draw a sample of the bodily fluid from the patient through the patient end. The apparatus can include a spectroscopic analyzer positioned to analyze at least a portion of the sample; a processor in communication with or incorporated into the spectroscopic analyzer; and stored program instructions executable by the processor to obtain measurements of two or more properties of the sample.
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公开(公告)号:US20190350507A1
公开(公告)日:2019-11-21
申请号:US16271653
申请日:2019-02-08
Applicant: OptiScan Biomedical Corporation
Inventor: Eugene Lim , Roger Tong , Peter Rule , James R. Braig , Richard Keenan , David N. Callicoat
IPC: A61B5/157 , G16H20/17 , A61M5/172 , A61B5/00 , A61M39/10 , A61B5/145 , A61B5/1455 , A61B5/153 , A61B5/155 , A61B5/15 , G01N21/03 , G01N21/07 , G01N33/49 , A61B5/1459
Abstract: Systems and method are disclosed for determining a concentration of an analyte in a fluid (e.g., blood). The system can draw blood from a patient and deliver the blood to a sample cell. A particular component of the fluid (e.g., plasma) may be separated and/or positioned such that the concentration of the analyte is measured in the particular component of the fluid (e.g., plasma). The sample cell can include a sample container that has two window pieces. The system can have a fluid passage having a tip configured to mate with a multi-lumen catheter without leaking. The multi-lumen catheter can have proximal and distal ports. A fluid pressure system can be configured to periodically draw fluid from vasculature through a proximal intravascular opening and the proximal port while maintaining a low pressure and/or flow rate to thereby reduce risk of reversing the fluid flow in a vessel and drawing infusates upstream into another intravascular opening.
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公开(公告)号:US10383561B2
公开(公告)日:2019-08-20
申请号:US15868895
申请日:2018-01-11
Applicant: OptiScan Biomedical Corporation
Inventor: Richard Keenan , Jeffrey Chiou , Jennifer Gable , Kenneth I-Shen Li , Roger Tong , Mike Recknor , James R. Braig
Abstract: A fluid handling system for use in bodily fluid analysis. The system comprises a first fluid handling module configured to interface with a main instrument. The first fluid handling module has a first fluid handling network and the first fluid handling network includes an infusate passage and an infusion fluid pressure member suitable for moving fluid within the infusate passage. The fluid handling system also has a second fluid handling module separate from the first module which is configured to interface with the main instrument. The second fluid handling module has a second fluid handling network and at least one sample analysis cell which is accessible via the second fluid handling network. The first and second modules are configured to interconnect and provide fluid communication between the first and second fluid handling network and the sample cells.
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公开(公告)号:US08992443B2
公开(公告)日:2015-03-31
申请号:US13946967
申请日:2013-07-19
Applicant: OptiScan Biomedical Corporation
Inventor: Jennifer H. Gable , James R. Braig , Kenneth I. Li , Mark Wechsler , Peng Zheng , Richard Keenan
IPC: A61B5/00 , B65D81/00 , A61M37/00 , A61B5/15 , A61B5/155 , A61B5/145 , A61M5/172 , A61B5/1455 , A61B5/157 , A61B10/00 , A61M5/142 , A61M5/168 , A61M5/36 , A61M5/38 , G01N21/03
CPC classification number: A61B5/157 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/0086 , A61B5/1411 , A61B5/1427 , A61B5/1451 , A61B5/14517 , A61B5/14532 , A61B5/14535 , A61B5/14546 , A61B5/1455 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/150267 , A61B5/150358 , A61B5/150755 , A61B5/150862 , A61B5/150992 , A61B5/153 , A61B5/155 , A61B5/4839 , A61B10/0064 , A61B2560/0443 , A61M5/14212 , A61M5/14232 , A61M5/16854 , A61M5/1723 , A61M5/365 , A61M5/38 , A61M2205/12 , A61M2205/3306 , A61M2230/20 , A61M2230/201 , G01N21/03 , G01N21/3577 , G01N2021/3595 , G01N2201/02 , G01N2201/061 , G06F19/00 , Y10T137/4478 , Y10T137/7722 , Y10T137/86485 , Y10T436/111666 , Y10T436/2575
Abstract: A fluid handling module that is removably engageable with a bodily fluid analyzer is provided. The module may comprise a fluid handling element, and a fluid component separator that is accessible via the fluid handling element and configured to separate at least one component of a bodily fluid transported to the fluid component separator. The fluid handling element may have at least one control element interface.
Abstract translation: 提供了可移除地与体液分析器接合的流体处理模块。 模块可以包括流体处理元件和流体部件分离器,其可经由流体处理元件接近并且被配置为分离输送到流体组分分离器的体液的至少一个组分。 流体处理元件可以具有至少一个控制元件接口。
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公开(公告)号:US20180296147A1
公开(公告)日:2018-10-18
申请号:US15868895
申请日:2018-01-11
Applicant: OptiScan Biomedical Corporation
Inventor: Richard Keenan , Jeffrey Chiou , Jennifer Gable , Kenneth I-Shen Li , Roger Tong , Mike Recknor , James R. Braig
CPC classification number: A61B5/157 , G01N33/50 , H05K999/99
Abstract: A fluid handling system for use in bodily fluid analysis. The system comprises a first fluid handling module configured to interface with a main instrument. The first fluid handling module has a first fluid handling network and the first fluid handling network includes an infusate passage and an infusion fluid pressure member suitable for moving fluid within the infusate passage. The fluid handling system also has a second fluid handling module separate from the first module which is configured to interface with the main instrument. The second fluid handling module has a second fluid handling network and at least one sample analysis cell which is accessible via the second fluid handling network. The first and second modules are configured to interconnect and provide fluid communication between the first and second fluid handling network and the sample cells.
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公开(公告)号:US09554742B2
公开(公告)日:2017-01-31
申请号:US14589867
申请日:2015-01-05
Applicant: OptiScan Biomedical Corporation
Inventor: Eugene Lim , Roger Tong , Peter Rule , James R. Braig , Richard Keenan , David N. Callicoat
IPC: G01N33/48 , A61B5/157 , A61B5/1455 , A61B5/15 , G01N33/49 , A61B5/00 , A61B5/155 , A61B5/145 , A61B5/1459 , A61B5/153 , G01N21/03 , G01N21/07 , A61M5/172 , G06F19/00 , A61M5/142 , G01N21/35 , A61M5/14 , A61M5/168
CPC classification number: A61B5/157 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/14552 , A61B5/14557 , A61B5/1459 , A61B5/15003 , A61B5/150221 , A61B5/150229 , A61B5/150236 , A61B5/150267 , A61B5/150755 , A61B5/150992 , A61B5/153 , A61B5/155 , A61B5/6866 , A61B2562/0233 , A61B2562/0238 , A61M5/1415 , A61M5/142 , A61M5/16827 , A61M5/1723 , A61M2005/14208 , A61M2205/12 , A61M2205/128 , G01N21/03 , G01N21/07 , G01N21/35 , G01N33/491 , G01N2021/0346 , G06F19/00 , G06F19/3468
Abstract: Systems and method are disclosed for determining a concentration of an analyte in a fluid (e.g., blood). The system can draw blood from a patient and deliver the blood to a sample cell. A particular component of the fluid (e.g., plasma) may be separated and/or positioned such that the concentration of the analyte is measured in the particular component of the fluid (e.g., plasma). The sample cell can include a sample container that has two window pieces. The system can have a fluid passage having a tip configured to mate with a multi-lumen catheter without leaking. The multi-lumen catheter can have proximal and distal ports. A fluid pressure system can be configured to periodically draw fluid from vasculature through a proximal intravascular opening and the proximal port while maintaining a low pressure and/or flow rate to thereby reduce risk of reversing the fluid flow in a vessel and drawing infusates upstream into another intravascular opening.
Abstract translation: 公开了用于确定流体(例如血液)中分析物浓度的系统和方法。 该系统可以从患者抽取血液并将血液输送到样品池。 流体(例如,等离子体)的特定组分可以被分离和/或定位,使得在流体的特定组分(例如,等离子体)中测量分析物的浓度。 样品池可以包括具有两个窗件的样品容器。 该系统可以具有流体通道,其具有构造成与多腔导管配合而不泄漏的顶端。 多腔导管可以具有近端和远端端口。 流体压力系统可以被配置成周期性地从脉管系统中抽取流体通过近端血管内开口和近端口,同时保持低压和/或流速,从而降低反转容器中的流体流动的风险,并将输注物上游到另一个 血管内开放。
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公开(公告)号:US20150168294A1
公开(公告)日:2015-06-18
申请号:US14335491
申请日:2014-07-18
Applicant: OptiScan Biomedical Corporation
Inventor: James R. Braig , Peter Rule , Philip C. Hartstein , Bernhard B. Sterling , Jennifer H. Gable , Kenneth I. Li
CPC classification number: A61B5/157 , A61B5/01 , A61B5/1411 , A61B5/14532 , A61B5/1455 , A61B5/150022 , A61B5/150083 , A61B5/150213 , A61B5/150358 , A61B5/150412 , A61B5/150458 , A61B5/150503 , A61B5/150618 , A61B5/150717 , A61B5/15087 , A61B5/151 , A61B5/15107 , A61B5/15136 , A61B5/1514 , A61B5/15194 , A61B5/6826 , A61B5/6838 , A61B10/0045 , A61B2562/0295 , A61B2562/12 , G01N21/03 , G01N21/0332 , G01N21/35 , G01N21/3577 , G01N21/3581 , G01N33/49 , G01N33/66 , G01N2021/0389 , G01N2201/02 , G01N2201/068
Abstract: A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.
Abstract translation: 能够在患者附近部署的无试剂全血分析物检测系统具有能够发射包括光谱带的辐射束的源。 全血系统还具有光束的光路中的检测器。 全血系统还具有容纳源和检测器的壳体。 全血系统还具有位于束的光路中的样品元件。 样品元件具有不消除光谱带中的辐射束的透射率的样品池和样品池壁。
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公开(公告)号:US10660557B2
公开(公告)日:2020-05-26
申请号:US16271653
申请日:2019-02-08
Applicant: OptiScan Biomedical Corporation
Inventor: Eugene Lim , Roger Tong , Peter Rule , James R. Braig , Richard Keenan , David N. Callicoat
IPC: A61B5/157 , A61B5/00 , A61B5/145 , A61B5/1455 , A61B5/153 , A61B5/155 , A61M39/10 , A61B5/15 , A61B5/1459 , A61M5/172 , G01N21/03 , G01N21/07 , G01N33/49 , G06F19/00 , G16H20/17 , A61M5/14 , A61M5/142 , A61M5/168 , G01N21/35
Abstract: Systems and method are disclosed for determining a concentration of an analyte in a fluid (e.g., blood). The system can draw blood from a patient and deliver the blood to a sample cell. A particular component of the fluid (e.g., plasma) may be separated and/or positioned such that the concentration of the analyte is measured in the particular component of the fluid (e.g., plasma). The sample cell can include a sample container that has two window pieces. The system can have a fluid passage having a tip configured to mate with a multi-lumen catheter without leaking. The multi-lumen catheter can have proximal and distal ports. A fluid pressure system can be configured to periodically draw fluid from vasculature through a proximal intravascular opening and the proximal port while maintaining a low pressure and/or flow rate to thereby reduce risk of reversing the fluid flow in a vessel and drawing infusates upstream into another intravascular opening.
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公开(公告)号:US10201303B2
公开(公告)日:2019-02-12
申请号:US15418485
申请日:2017-01-27
Applicant: OptiScan Biomedical Corporation
Inventor: Eugene Lim , Roger Tong , Peter Rule , James R. Braig , Richard Keenan , David N. Callicoat
IPC: A61B5/157 , A61B5/00 , A61B5/155 , A61B5/145 , A61B5/1455 , A61B5/153 , A61M39/10 , A61B5/15 , A61B5/1459 , A61M5/172 , G01N21/03 , G01N21/07 , G01N33/49 , G06F19/00 , A61M5/14 , A61M5/142 , A61M5/168 , G01N21/35
Abstract: Systems and method are disclosed for determining a concentration of an analyte in a fluid (e.g., blood). The system can draw blood from a patient and deliver the blood to a sample cell. A particular component of the fluid (e.g., plasma) may be separated and/or positioned such that the concentration of the analyte is measured in the particular component of the fluid (e.g., plasma). The sample cell can include a sample container that has two window pieces. The system can have a fluid passage having a tip configured to mate with a multi-lumen catheter without leaking. The multi-lumen catheter can have proximal and distal ports. A fluid pressure system can be configured to periodically draw fluid from vasculature through a proximal intravascular opening and the proximal port while maintaining a low pressure and/or flow rate to thereby reduce risk of reversing the fluid flow in a vessel and drawing infusates upstream into another intravascular opening.
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公开(公告)号:US09913604B2
公开(公告)日:2018-03-13
申请号:US14954869
申请日:2015-11-30
Applicant: OptiScan Biomedical Corporation
Inventor: James R. Braig , Peter Rule
IPC: A61B5/15 , A61B5/145 , A61B5/157 , A61B5/1455 , A61B5/00 , A61M5/172 , G01N21/27 , G06F19/00 , A61B5/153 , A61B5/155 , A61B5/1486 , A61M5/142 , A61M5/168 , A61M5/36 , A61M5/38 , G01N21/35
CPC classification number: A61B5/150992 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/14557 , A61B5/1486 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/150267 , A61B5/150389 , A61B5/150503 , A61B5/150755 , A61B5/150854 , A61B5/153 , A61B5/155 , A61B5/157 , A61B5/4839 , A61M5/14212 , A61M5/14232 , A61M5/16854 , A61M5/1723 , A61M5/365 , A61M5/38 , A61M2205/12 , A61M2230/20 , A61M2230/201 , G01N21/274 , G01N21/35 , G01N2201/1293 , G06F19/00 , G06F19/3468 , G16H10/40 , G16H20/17
Abstract: In certain embodiments, a sampling assembly is for use with a main analyzer. The main analyzer is configured to sense an analyte in a body fluid obtained from a patient through a first fluid passageway extending from the main analyzer. The sampling assembly includes an instrument portion separate from the main analyzer and including at least one sensor. The instrument portion is removably engaged with the first fluid passageway. The at least one sensor is in sensing engagement with the first fluid passageway such that the at least one sensor can sense a property of a fluid within the first fluid passageway.
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