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公开(公告)号：US10753863B1
公开(公告)日：2020-08-25
申请号：US16688919
申请日：2019-11-19
Applicant: Photon Systems, Inc.
Inventor： William F. Hug , Ray D. Reid , Rohit Bhartia , Arthur L. Lane
Abstract: Spectroscopic chemical analysis methods and apparatus are disclosed which employ deep ultraviolet (e.g. in the 200 nm to 300 nm spectral range) electron beam pumped wide bandgap semiconductor lasers, incoherent wide bandgap semiconductor light emitting devices, and hollow cathode metal ion lasers to perform non-contact, non-invasive detection of unknown chemical analytes. These deep ultraviolet sources enable dramatic size, weight and power consumption reductions of chemical analysis instruments. In some embodiments, Raman spectroscopic detection methods and apparatus use ultra-narrow-band angle tuning filters, acousto-optic tuning filters, and temperature tuned filters to enable ultra-miniature analyzers for chemical identification. In some embodiments Raman analysis is conducted along with photoluminescence spectroscopy (i.e. fluorescence and/or phosphorescence spectroscopy) to provide high levels of sensitivity and specificity in the same instrument.
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公开(公告)号：US09909990B1
公开(公告)日：2018-03-06
申请号：US15263063
申请日：2016-09-12
Applicant: Photon Systems, Inc.
Inventor： William F. Hug , Rohit Bhartia , Ray D. Reid , Arthur L. Lane
IPC: G01N21/64
CPC classification number: G01N21/64 , G01J3/10 , G01J3/36 , G01J3/44 , G01N21/6486 , G01N21/65 , G01N21/8806 , G01N27/44721 , G01N33/0047 , G01N2021/6421 , G01N2021/6471 , G01N2201/06113 , G01N2201/0612 , G01N2201/062 , G01N2201/126
Abstract: Naphthalene, benzene, toluene, xylene, and other volatile organic compounds VOCs have been identified as serious health hazards. Embodiments of the invention are directed to methods and apparatus for near-real-time in-situ detection and accumulated dose measurement of exposure to naphthalene vapor and other hazardous gaseous VOCs. The methods and apparatus employ excitation of fluorophors native or endogenous to compounds of interest using light sources emitting in the ultraviolet below 300 nm and measurement of native fluorescence emissions in distinct wavebands above the excitation wavelength. The apparatus of some embodiments are cell-phone-sized sensor/dosimeter “badges” to be worn by personnel potentially exposed to hazardous VOCs. The badge sensor of some embodiments provides both real time detection and data logging of exposure to naphthalene or other VOCs of interest from which both instantaneous and accumulated dose can be determined.
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公开(公告)号：US10895533B1
公开(公告)日：2021-01-19
申请号：US16820309
申请日：2020-03-16
Applicant: Photon Systems, Inc.
Inventor： William F. Hug , Röhit Bhartia , Ray D. Reid , Arthur L. Lane
Abstract: Naphthalene, benzene, toluene, xylene, and other volatile organic compounds VOCs have been identified as serious health hazards. Embodiments of the invention are directed to methods and apparatus for near-real-time in-situ detection and accumulated dose measurement of exposure to naphthalene vapor and other hazardous gaseous VOCs. The methods and apparatus employ excitation of fluorophors native or endogenous to compounds of interest using light sources emitting in the ultraviolet below 300 nm and measurement of native fluorescence emissions in distinct wavebands above the excitation wavelength. The apparatus of some embodiments are cell-phone-sized sensor/dosimeter “badges” to be worn by personnel potentially exposed to hazardous VOCs. The badge sensor of some embodiments provides both real time detection and data logging of exposure to naphthalene or other VOCs of interest from which both instantaneous and accumulated dose can be determined.
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公开(公告)号：US09915603B1
公开(公告)日：2018-03-13
申请号：US15432865
申请日：2017-02-14
Applicant: Photon Systems, Inc.
Inventor： William F. Hug , Ray D. Reid , Rohit Bhartia , Arthur L. Lane
CPC classification number: G01N21/33 , G01J3/10 , G01J3/36 , G01J3/44 , G01N21/64 , G01N21/645 , G01N21/65 , G01N27/44721 , G01N2021/6421 , G01N2021/6471 , G01N2201/06113 , G01N2201/0612 , G01N2201/068
Abstract: Spectroscopic chemical analysis methods and apparatus are disclosed which employ deep ultraviolet (e.g. in the 200 nm to 300 nm spectral range) electron beam pumped wide bandgap semiconductor lasers, incoherent wide bandgap semiconductor light emitting devices, and hollow cathode metal ion lasers to perform non-contact, non-invasive detection of unknown chemical analytes. These deep ultraviolet sources enable dramatic size, weight and power consumption reductions of chemical analysis instruments. In some embodiments, Raman spectroscopic detection methods and apparatus use ultra-narrow-band angle tuning filters, acousto-optic tuning filters, and temperature tuned filters to enable ultra-miniature analyzers for chemical identification. In some embodiments Raman analysis is conducted along with photoluminescence spectroscopy (i.e. fluorescence and/or phosphorescence spectroscopy) to provide high levels of sensitivity and specificity in the same instrument.
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公开(公告)号：US11262301B1
公开(公告)日：2022-03-01
申请号：US17013469
申请日：2020-09-04
Applicant: Photon Systems, Inc.
Inventor： William F. Hug , Rohit Bhartia , Ray D. Reid , Arthur L. Lane
Abstract: Naphthalene, benzene, toluene, xylene, and other volatile organic compounds VOCs have been identified as serious health hazards. Embodiments of the invention are directed to methods and apparatus for near-real-time in-situ detection and accumulated dose measurement of exposure to naphthalene vapor and other hazardous gaseous VOCs. The methods and apparatus employ excitation of fluorophors native or endogenous to compounds of interest using light sources emitting in the ultraviolet below 300 nm and measurement of native fluorescence emissions in distinct wavebands above the excitation wavelength. The apparatus of some embodiments are cell-phone-sized sensor/dosimeter “badges” to be worn by personnel potentially exposed to hazardous VOCs. The badge sensor of some embodiments provides both real time detection and data logging of exposure to naphthalene or other VOCs of interest from which both instantaneous and accumulated dose can be determined.
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Patent Agency Ranking
公开(公告)号：US09568418B1
公开(公告)日：2017-02-14
申请号：US14313987
申请日：2014-06-24
Applicant: Photon Systems
Inventor： William F. Hug , Ray D. Reid , Rohit Bhartia , Arthur L. Lane
CPC classification number: G01N21/33 , G01J3/10 , G01J3/36 , G01J3/44 , G01N21/64 , G01N21/645 , G01N21/65 , G01N27/44721 , G01N2021/6421 , G01N2021/6471 , G01N2201/06113 , G01N2201/0612 , G01N2201/068
Abstract: Spectroscopic chemical analysis methods and apparatus are disclosed which employ deep ultraviolet (e.g. in the 200 nm to 300 nm spectral range) electron beam pumped wide bandgap semiconductor lasers, incoherent wide bandgap semiconductor light emitting devices, and hollow cathode metal ion lasers to perform non-contact, non-invasive detection of unknown chemical analytes. These deep ultraviolet sources enable dramatic size, weight and power consumption reductions of chemical analysis instruments. In some embodiments, Raman spectroscopic detection methods and apparatus use ultra-narrow-band angle tuning filters, acousto-optic tuning filters, and temperature tuned filters to enable ultra-miniature analyzers for chemical identification. In some embodiments Raman analysis is conducted along with photoluminescence spectroscopy (i.e. fluorescence and/or phosphorescence spectroscopy) to provide high levels of sensitivity and specificity in the same instrument.
Abstract translation: 公开了使用深紫外线（例如在200nm至300nm光谱范围内）的电子束泵浦宽带隙半导体激光器，非相干宽带隙半导体发光器件和空心阴极金属离子激光器的光谱化学分析方法和装置， 接触，未知化学分析物的非侵入性检测。 这些深紫外线源可以显着降低化学分析仪器的体积，重量和功耗。 在一些实施例中，拉曼光谱检测方法和装置使用超窄带角度调谐滤波器，声光调谐滤波器和温度调节滤波器，以使超微型分析仪能够进行化学鉴定。 在一些实施方案中，拉曼分析与光致发光光谱（即荧光和/或磷光光谱）一起进行，以在相同的仪器中提供高水平的灵敏度和特异性。
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7.发明授权Native fluorescence detection methods, devices, and systems for organic compounds 有权有机化合物的天然荧光检测方法，装置和系统公开(公告)号：US09442070B1
公开(公告)日：2016-09-13
申请号：US14313994
申请日：2014-06-24
Applicant: Photon Systems
Inventor： William F. Hug , Rohit Bhartia , Ray D. Reid , Arthur L. Lane
CPC classification number: G01N21/64 , G01J3/10 , G01J3/36 , G01J3/44 , G01N21/6486 , G01N21/65 , G01N21/8806 , G01N27/44721 , G01N33/0047 , G01N2021/6421 , G01N2021/6471 , G01N2201/06113 , G01N2201/0612 , G01N2201/062 , G01N2201/126
Abstract: Naphthalene, benzene, toluene, xylene, and other volatile organic compounds VOCs have been identified as serious health hazards. Embodiments of the invention are directed to methods and apparatus for near-real-time in-situ detection and accumulated dose measurement of exposure to naphthalene vapor and other hazardous gaseous VOCs. The methods and apparatus employ excitation of fluorophors native or endogenous to compounds of interest using light sources emitting in the ultraviolet below 300 nm and measurement of native fluorescence emissions in distinct wavebands above the excitation wavelength. The apparatus of some embodiments are cell-phone-sized sensor/dosimeter “badges” to be worn by personnel potentially exposed to hazardous VOCs. The badge sensor of some embodiments provides both real time detection and data logging of exposure to naphthalene or other VOCs of interest from which both instantaneous and accumulated dose can be determined.
Abstract translation: 萘，苯，甲苯，二甲苯等挥发性有机化合物已经被认定为严重的健康危害。 本发明的实施方案涉及用于接近实时原位检测和暴露于萘蒸气和其它有害气体挥发性有机化合物的累积剂量测量的方法和装置。 所述方法和装置使用在300nm以下的紫外线发射的光源并且在激发波长以上的不同波段中测量天然荧光发射，使用天然或内源的荧光体的激发。 一些实施例的装置是由潜在地暴露于危险VOC的人员佩戴的手机尺寸的传感器/剂量计“徽章”。 一些实施例的徽章传感器既提供实时检测和暴露于萘或其它感兴趣的VOC的数据记录，也可以从该值记录即时和累积剂量。
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公开(公告)号：US11448598B1
公开(公告)日：2022-09-20
申请号：US17374902
申请日：2021-07-13
Applicant: Photon Systems, Inc.
Inventor： Rohit Bhartia , Michael R. Reid , William F. Hug , Ray D. Reid
IPC: G01N21/64 , G01N21/33 , G01N33/569 , G01N21/3577 , G01N21/359 , G01N21/65 , G01N21/17
Abstract: Methods, apparatus, and systems provide improved identification of selected biohazard and/or biohazard signatures from complex in vivo or in vitro samples and include deep UV native fluorescence spectroscopic analysis for multiple locations of a sample wherein classification results for individual locations are combined and spatially correlated to provide a positive or negative conclusion of biohazard signature presence (e.g., for signatures for viruses, bacteria, and diseases including SARS-CoV-2 and its variants and COVID-19 and its variants). Improvements include one or more of reduced sample processing time (minutes to fractions of a minute), reduced sampling cost (dollars to fractions of a dollar), high conclusion reliability (rivaling real time RT-PCR). Some embodiments may incorporate a stage or scanning mirror system to provide movement of a sample relative to an excitation exposure location. Some embodiments may incorporate Raman or phosphorescence spectroscopic analysis as well as imaging systems.
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公开(公告)号：US10890533B1
公开(公告)日：2021-01-12
申请号：US16688894
申请日：2019-11-19
Applicant: Photon Systems, Inc.
Inventor： William F. Hug , Ray D. Reid , Rohit Bhartia , Arthur L. Lane
Abstract: Spectroscopic chemical analysis methods and apparatus are disclosed which employ deep ultraviolet (e.g. in the 200 nm to 300 nm spectral range) electron beam pumped wide bandgap semiconductor lasers, incoherent wide bandgap semiconductor light emitting devices, and hollow cathode metal ion lasers to perform non-contact, non-invasive detection of unknown chemical analytes. These deep ultraviolet sources enable dramatic size, weight and power consumption reductions of chemical analysis instruments. In some embodiments, Raman spectroscopic detection methods and apparatus use ultra-narrow-band angle tuning filters, acousto-optic tuning filters, and temperature tuned filters to enable ultra-miniature analyzers for chemical identification. In some embodiments Raman analysis is conducted along with photoluminescence spectroscopy (i.e. fluorescence and/or phosphorescence spectroscopy) to provide high levels of sensitivity and specificity in the same instrument.
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公开(公告)号：US10598596B1
公开(公告)日：2020-03-24
申请号：US16362453
申请日：2019-03-22
Applicant: Photon Systems, Inc.
Inventor： William F. Hug , Rohit Bhartia , Ray D. Reid , Arthur L. Lane
Abstract: Naphthalene, benzene, toluene, xylene, and other volatile organic compounds VOCs have been identified as serious health hazards. Embodiments of the invention are directed to methods and apparatus for near-real-time in-situ detection and accumulated dose measurement of exposure to naphthalene vapor and other hazardous gaseous VOCs. The methods and apparatus employ excitation of fluorophors native or endogenous to compounds of interest using light sources emitting in the ultraviolet below 300 nm and measurement of native fluorescence emissions in distinct wavebands above the excitation wavelength. The apparatus of some embodiments are cell-phone-sized sensor/dosimeter “badges” to be worn by personnel potentially exposed to hazardous VOCs. The badge sensor of some embodiments provides both real time detection and data logging of exposure to naphthalene or other VOCs of interest from which both instantaneous and accumulated dose can be determined.
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