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公开(公告)号：US20210346143A1
公开(公告)日：2021-11-11
申请号：US16336445
申请日：2017-09-08
Applicant: PneumRx, Inc.
Inventor： David Lehrberg , Mark Mathis , Jeffrey Etter , Verna Rodriguez
Abstract: A container for a medical device having a housing defining a cavity for receiving the device, a coupling zone external to the cavity, and an exit aperture between the cavity and the coupling zone; and a bearing surface located within the cavity, the bearing surface, exit aperture and coupling zone defining an exit path along which the device can be moved for deployment from the container. The bearing surface is spaced from the exit aperture and arranged, together with the coupling zone, such that the exit path is substantially straight. The cavity is approximately cylindrical, and the bearing surface, the exit aperture, and the coupling zone are aligned such that the exit path extends in a direction that is substantially tangential to the cavity. The housing comprises a two part structure joined together in a plane substantially orthogonal to the exit path. The housing defines a substantially unobstructed cavity for receiving the device. The housing in the coupling zone defines a slot through which the exit path extends, the slot defining a restricted space for deployment of a capture device.
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公开(公告)号：US10543053B2
公开(公告)日：2020-01-28
申请号：US15719751
申请日：2017-09-29
Applicant: PneumRx, Inc.
Inventor： David Lehrberg , Jeffrey W. Etter , Mark L. Mathis , Verna Rodriguez
Abstract: A container for a medical device having a housing defining a cavity for receiving a device, such as a lung volume reduction coil, is disclosed. In some embodiments, the container includes a coupling zone external to the cavity, an exit aperture between the cavity and the coupling zone, and a bearing surface located within the cavity, the bearing surface, exit aperture and coupling zone defining an exit path along which the device can be moved for deployment from the container. The bearing surface is spaced from the exit aperture and arranged, together with the coupling zone, such that the exit path is substantially straight. In some embodiments, the cavity may be approximately cylindrical, and the bearing surface, the exit aperture, and the coupling zone are aligned such that the exit path extends in a direction that is substantially tangential to the cavity.
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公开(公告)号：US20180092704A1
公开(公告)日：2018-04-05
申请号：US15719751
申请日：2017-09-29
Applicant: PneumRx, Inc.
Inventor： David Lehrberg , Jeffrey W. Etter , Mark L. Mathis , Verna Rodriguez
Abstract: A container for a medical device having a housing defining a cavity for receiving a device, such as a lung volume reduction coil, is disclosed. In some embodiments, the container includes a coupling zone external to the cavity, an exit aperture between the cavity and the coupling zone, and a bearing surface located within the cavity, the bearing surface, exit aperture and coupling zone defining an exit path along which the device can be moved for deployment from the container. The bearing surface is spaced from the exit aperture and arranged, together with the coupling zone, such that the exit path is substantially straight. In some embodiments, the cavity may be approximately cylindrical, and the bearing surface, the exit aperture, and the coupling zone are aligned such that the exit path extends in a direction that is substantially tangential to the cavity.
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公开(公告)号：US10555736B2
公开(公告)日：2020-02-11
申请号：US15719792
申请日：2017-09-29
Applicant: PneumRx, Inc.
Inventor： Timothy Machold , Mark Mathis , Verna Rodriguez , Scott Kaarto
Abstract: Guidewires suitable for use in a system for implanting a lung volume reduction device are disclosed. The guidewire includes an outer sheath having proximal and distal ends, and comprising a proximal section, a transition section, and a distal section. The proximal section extends from the proximal end of the sheath to the transition section, and the distal section extends from the transition section to the distal end of the sheath. The distal section defines a bore extending from the transition section to the distal end of the sheath and an inner core having proximal and distal ends. The inner core extends through the bore of the distal section of the sheath, wherein the inner core is fixed to the sheath at the transition section, and wherein the distal end of the inner core is fixed to the distal end of the sheath at the distal end of the sheath.
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公开(公告)号：US20170156732A1
公开(公告)日：2017-06-08
申请号：US15432853
申请日：2017-02-14
Applicant: PneumRx, Inc.
Inventor： David Lehrberg , Mark L. Mathis , Verna Rodriguez , Jeffrey Etter , Kevin Mitz , Christoph Steven
IPC: A61B17/12 , A61B90/98 , A61B17/128 , A61B90/96
CPC classification number: A61B17/12104 , A61B17/12036 , A61B17/12145 , A61B17/1285 , A61B90/96 , A61B90/98 , A61B2017/00367 , A61B2017/00809 , A61B2017/1205 , A61B2017/2923
Abstract: Methods, systems and devices are disclosed for the efficient and coordinated delivery of COPD treatment to the lung(s) of a patient. A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to an airway of a patient in a constrained configuration and to change to a tissue-compressing configuration when deployed at a target zone to provide treatment to the lung airway. The invention further discloses a method of quickly and efficiently deploying the device using a single coordinated motion or signal which may be particularly useful when multiple devices are deployed at multiple target zones.
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Patent Agency Ranking
公开(公告)号：US10390838B1
公开(公告)日：2019-08-27
申请号：US14831007
申请日：2015-08-20
Applicant: PneumRx, Inc.
Inventor： Mark Mathis , Verna Rodriguez
Abstract: The present invention generally provides improved medical devices, systems, and methods, particularly for treating one or both lungs of a patient with an implant, such as a coil, having a strength tuned to a patient's tissue treatment region. More particularly, embodiments of the present invention include a method for treating a lung of a patient with chronic obstructive pulmonary disease. The method comprises determining a regional tissue density of at least a portion of lung tissue of the patient and selecting between first and second coils based on the determined regional tissue density of the portion of lung tissue. In particular, the first coil has a first austenite final tuning and second coil has a second austenite final tuning different than the first tuning. Determining may comprise imaging at least the portion of lung tissue of the patient so as to identify a localized lung tissue density. Selecting may comprise matching the determined tissue density of the treatment region to a tuned strength of the first or second coil.
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公开(公告)号：US20180092647A1
公开(公告)日：2018-04-05
申请号：US15719792
申请日：2017-09-29
Applicant: PneumRx, Inc.
Inventor： Timothy Machold , Mark Mathis , Verna Rodriguez , Scott Kaarto
Abstract: Guidewires suitable for use in a system for implanting a lung volume reduction device are disclosed. The guidewire includes an outer sheath having proximal and distal ends, and comprising a proximal section, a transition section, and a distal section. The proximal section extends from the proximal end of the sheath to the transition section, and the distal section extends from the transition section to the distal end of the sheath. The distal section defines a bore extending from the transition section to the distal end of the sheath and an inner core having proximal and distal ends. The inner core extends through the bore of the distal section of the sheath, wherein the inner core is fixed to the sheath at the transition section, and wherein the distal end of the inner core is fixed to the distal end of the sheath at the distal end of the sheath.
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公开(公告)号：US20200146688A1
公开(公告)日：2020-05-14
申请号：US16743092
申请日：2020-01-15
Applicant: PneumRx, Inc.
Inventor： Timothy Machold , Mark Mathis , Verna Rodriguez , Scott Kaarto
Abstract: Embodiments include a transition section for coupling a distal section and a proximal section of the guidewire. The transition section includes a main body having a first outer diameter; proximal and distal pin extensions having second and third outer diameters, wherein the proximal pin extension is configured to be fixed to the proximal section of the guidewire, and the distal pin extension is configured to be inserted into and fixed to the distal section of the guidewire. The distal pin extension includes a bore for receiving an inner core of the distal section of the guidewire. The first outer diameter may be greater than the second and third outer diameters. Also disclosed are methods of manufacturing a guidewire with such a transition section.
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公开(公告)号：US20190350588A1
公开(公告)日：2019-11-21
申请号：US16417183
申请日：2019-05-20
Applicant: PneumRx, Inc.
Inventor： Verna Rodriguez , Kinman Hong
Abstract: The invention provides improved medical devices, therapeutic treatment systems, and treatment methods for treatment of the lung. The invention includes methods, systems, and devices for applying a first lung volume reduction action to the functionally impaired lung tissue so as to reduce its volume to less than a pre-treatment volume; and applying a pro-inflammatory stimulus to the functionally impaired lung tissue having reduced volume, that stimulus being sufficient to induce fibrosis in the functionally impaired lung tissue. The pro-inflammatory stimulus may be separate and additional to that of the lung volume reduction action.
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公开(公告)号：US20190336131A1
公开(公告)日：2019-11-07
申请号：US16454845
申请日：2019-06-27
Applicant: PneumRx, Inc.
Inventor： Mark Mathis , Verna Rodriguez
Abstract: The present invention generally provides improved medical devices, systems, and methods, particularly for treating one or both lungs of a patient with an implant, such as a coil, having a strength tuned to a patient's tissue treatment region. More particularly, embodiments of the present invention include implant assemblies and systems for treating a lung of a patient with chronic obstructive pulmonary disease. The implant assemblies may comprise an elongate body comprising an alloy that may be characterized by its austenite final tuning. The implant may include multiple portions that may be of different austenite final tunings.
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