公开(公告)号：US09640376B1

公开(公告)日：2017-05-02

申请号：US14306020

申请日：2014-06-16

Applicant: Protein Metrics Inc.

Inventor： Christopher Becker ,  Marshall Bern ,  Yong Joo Kil ,  Michael Taejong Kim ,  Boyan Zhang

IPC: H01J49/00 ,  G06T11/20 ,  H01J49/02

CPC classification number: H01J49/0036 ,  G06T11/206 ,  H01J49/02

Abstract: This invention relates to graphical user-interactive displays for use in MS-based analysis of protein impurities, as well as methods and software for generating and using such. One aspect provides a user-interactive display comprising an extracted mass chromatogram (XIC), an MS1 spectrum and an MS2 spectrum, all simultaneously representing a user-selected peptide. Another aspect provides a user interactive display simultaneously presenting paired spectra (XIC, MS1 and/or MS2) for a variant peptide and its corresponding wildtype counterpart.

公开(公告)号：US10199206B2

公开(公告)日：2019-02-05

申请号：US15583752

申请日：2017-05-01

Applicant: Protein Metrics Inc.

Inventor： Christopher Becker ,  Marshall Bern ,  Yong Joo Kil ,  Michael Taejong Kim ,  Boyan Zhang

IPC: H01J49/00 ,  H01J49/02 ,  G06T11/20

Abstract: This invention relates to graphical user-interactive displays for use in MS-based analysis of protein impurities, as well as methods and software for generating and using such. One aspect provides a user-interactive display comprising an extracted mass chromatogram (XIC), an MS1 spectrum and an MS2 spectrum, all simultaneously representing a user-selected peptide. Another aspect provides a user interactive display simultaneously presenting paired spectra (XIC, MS1 and/or MS2) for a variant peptide and its corresponding wildtype counterpart.