公开(公告)号：US10354421B2

公开(公告)日：2019-07-16

申请号：US15066871

申请日：2016-03-10

Applicant: Protein Metrics Inc.

Inventor： Christopher Becker ,  Marshall Bern ,  Nicholas Bern ,  Yong Joo Kil ,  Richard Seipert ,  Michael Taejong Kim

IPC: G01N33/48 ,  G06T11/20 ,  G16B45/00 ,  G16B40/00

Abstract: Methods and apparatuses for the analysis of mass spectroscopic (MS) data as well as ultraviolet (UV) absorption data. In particular, described herein are tools and methods to assist in generating annotated peptide maps from a raw MS data.

公开(公告)号：US10199206B2

公开(公告)日：2019-02-05

申请号：US15583752

申请日：2017-05-01

Applicant: Protein Metrics Inc.

Inventor： Christopher Becker ,  Marshall Bern ,  Yong Joo Kil ,  Michael Taejong Kim ,  Boyan Zhang

IPC: H01J49/00 ,  H01J49/02 ,  G06T11/20

Abstract: This invention relates to graphical user-interactive displays for use in MS-based analysis of protein impurities, as well as methods and software for generating and using such. One aspect provides a user-interactive display comprising an extracted mass chromatogram (XIC), an MS1 spectrum and an MS2 spectrum, all simultaneously representing a user-selected peptide. Another aspect provides a user interactive display simultaneously presenting paired spectra (XIC, MS1 and/or MS2) for a variant peptide and its corresponding wildtype counterpart.

公开(公告)号：US09640376B1

公开(公告)日：2017-05-02

申请号：US14306020

申请日：2014-06-16

Applicant: Protein Metrics Inc.

Inventor： Christopher Becker ,  Marshall Bern ,  Yong Joo Kil ,  Michael Taejong Kim ,  Boyan Zhang

IPC: H01J49/00 ,  G06T11/20 ,  H01J49/02

CPC classification number: H01J49/0036 ,  G06T11/206 ,  H01J49/02

Abstract: This invention relates to graphical user-interactive displays for use in MS-based analysis of protein impurities, as well as methods and software for generating and using such. One aspect provides a user-interactive display comprising an extracted mass chromatogram (XIC), an MS1 spectrum and an MS2 spectrum, all simultaneously representing a user-selected peptide. Another aspect provides a user interactive display simultaneously presenting paired spectra (XIC, MS1 and/or MS2) for a variant peptide and its corresponding wildtype counterpart.