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    Drug delivery device and method
    1.
    发明授权
    Drug delivery device and method 有权

    公开(公告)号：US11439747B2

    公开(公告)日：2022-09-13

    申请号：US16152063

    申请日：2018-10-04

    Applicant: Purdue Research Foundation

    Inventor： Hyowon Lee ,  Bahar Dhowan

    IPC: A61M5/142 ,  A61M31/00 ,  A61B5/00 ,  A61M5/44 ,  A61K9/00 ,  A61M37/00 ,  A61K31/485 ,  A61B5/01

    Abstract: An implantable drug delivery device and method for delivering a drug to a living body. The device includes a housing having at least one opening, a reservoir within the housing adapted to contain a drug, a temporary seal closing the opening of the housing, and a heating element in thermal contact with the temporary seal. The heating element is adapted to generate heat in response to a magnetic field to melt the temporary seal and release a drug within the reservoir through the opening of the housing.

    DRAINAGE DEVICES HAVING SELF-CLEARING AND FLOW RESISTANCE CONTROL CAPABILITIES, AND MICROACTUATORS FOR USE THEREWITH
    3.
    发明申请
    DRAINAGE DEVICES HAVING SELF-CLEARING AND FLOW RESISTANCE CONTROL CAPABILITIES, AND MICROACTUATORS FOR USE THEREWITH 审中-公开

    公开(公告)号：US20190307608A1

    公开(公告)日：2019-10-10

    申请号：US16376288

    申请日：2019-04-05

    Applicant: Purdue Research Foundation

    Inventor： Hyowon Lee ,  Simon John ,  Hyunsu Park

    IPC: A61F9/007 ,  A61F9/00 ,  F16K99/00

    Abstract: Drainage devices have a self-clearing capability for reducing obstructions and a controllable flow restriction capability for controlling drainage flow, and microactuators for providing such capabilities. Such a microactuator includes a frame and an appendage anchored to the frame such that the frame supports the appendage, the frame at least partially surrounds the appendage, and the appendage is disposed in an opening or window defined by the frame. The appendage includes a platform and at least one beam that anchors the platform to the frame to enable the appendage to deflect out of a plane defined by the frame. The platform may include a ferromagnetic material that enables the appendage to deflect in response to an applied magnetic field.

    SELF-CLEARING CATHETERS AND METHODS OF USE THEREOF
    5.
    发明公开
    SELF-CLEARING CATHETERS AND METHODS OF USE THEREOF 审中-公开

    公开(公告)号：US20230405265A1

    公开(公告)日：2023-12-21

    申请号：US18459479

    申请日：2023-09-01

    Applicant: Purdue Research Foundation

    Inventor： Hyowon Lee

    IPC: A61M25/00

    CPC classification number: A61M25/0017 ,  Y10S977/931 ,  A61M25/0045 ,  A61M2025/0019 ,  A61M2025/0056 ,  A61M2205/36

    Abstract: A self-cleaning cannula for placement in a patient, including an elongated tube portion having an inner surface and an oppositely disposed outer surface, a first end fluidically connectable to a fluid source outside the patient and a second, oppositely disposed end for fluidically communicating with the patient, and a plurality of magnetic nanoparticles operationally connected to at least a portion of the cannula. The metallic nanoparticles may be energized by an applied oscillating magnetic field to heat the cannula.

    Microactuator systems, drainage devices equipped therewith, and methods of use
    6.
    发明授权
    Microactuator systems, drainage devices equipped therewith, and methods of use 有权

    公开(公告)号：US11534584B2

    公开(公告)日：2022-12-27

    申请号：US16689203

    申请日：2019-11-20

    Applicant: Purdue Research Foundation

    Inventor： Hyowon Lee ,  Qi Yang

    IPC: A61M27/00 ,  A61M25/00

    Abstract: Drainage devices and microactuator systems adapted to be incorporated into drainage devices to provide a self-clearing capability for reducing obstructions in the drainage devices and/or a self-monitoring capability to confirm the overall operating condition of the drainage devices and their microactuators. Such a microactuator system includes a microactuator having a base, a cantilever comprising a flexure extending from the base and a plate structure at a distal end of the flexure, a sensing element on the flexure for sensing deflection of the cantilever, and a device for inducing an oscillating deflection of the cantilever relative to the base.

    DRUG DELIVERY DEVICE AND METHOD
    8.
    发明申请
    DRUG DELIVERY DEVICE AND METHOD 审中-公开

    公开(公告)号：US20190125966A1

    公开(公告)日：2019-05-02

    申请号：US16152063

    申请日：2018-10-04

    Applicant: Purdue Research Foundation

    Inventor： Hyowon Lee ,  Bahar Dhowan

    IPC: A61M5/142 ,  A61M31/00 ,  A61B5/00

    Abstract: An implantable drug delivery device and method for delivering a drug to a living body. The device includes a housing having at least one opening, a reservoir within the housing adapted to contain a drug, a temporary seal closing the opening of the housing, and a heating element in thermal contact with the temporary seal. The heating element is adapted to generate heat in response to a magnetic field to melt the temporary seal and release a drug within the reservoir through the opening of the housing.

    MICROACTUATOR ENABLED SELF-CLEARING SYSTEM AND METHOD
    10.
    发明公开
    MICROACTUATOR ENABLED SELF-CLEARING SYSTEM AND METHOD 审中-公开

    公开(公告)号：US20230338700A1

    公开(公告)日：2023-10-26

    申请号：US18136657

    申请日：2023-04-19

    Applicant: Purdue Research Foundation

    Inventor： Hyowon Lee ,  Qi Yang

    IPC: A61M25/00 ,  A61B8/12

    CPC classification number: A61M25/0043 ,  A61B8/12 ,  A61M2025/0057

    Abstract: The self-clearing system includes a microactuator, a catheter lumen, and an actuation device. The microactuator includes a polyimide structural layer and a conduction layer. The polyimide structural layer has a main body and a flexure. The conduction layer is coupled to the polyimide structural layer. The catheter lumen is configured to accept the microactuator. The actuation device is configured to wirelessly engage the microactuator.

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