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公开(公告)号：US20190206668A1
公开(公告)日：2019-07-04
申请号：US16224191
申请日：2018-12-18
Applicant: Purdue Research Foundation , Purdue Research Foundation
Inventor： Robert Graham Cooks , Ahmed Mohamed Hamid , Alan Keith Jarmusch , Zheng Ouyang
CPC classification number: H01J49/0445 , C12N13/00 , C12Q1/04 , G01N2560/00 , H01J49/16
Abstract: The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples.
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公开(公告)号：US12154773B2
公开(公告)日：2024-11-26
申请号：US17144394
申请日：2021-01-08
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Dalton Snyder
Abstract: The invention generally relates to systems and methods for collision induced dissociation of ions in an ion trap. In certain aspects, the invention provides a system that includes a mass spectrometer having an ion trap, and a central processing unit (CPU). The CPU includes storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to generate one or more signals, and apply the one or more signals to the ion trap in a manner that all ions within the ion trap are fragmented at a same Mathieu q value.
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公开(公告)号：US12130255B2
公开(公告)日：2024-10-29
申请号：US18084827
申请日：2022-12-20
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Nicolás M. Morato , Dylan T. Holden
IPC: G01N27/64 , G01N27/622 , G01N27/626 , H01J49/04
CPC classification number: G01N27/622 , G01N27/626 , G01N27/64 , H01J49/0409
Abstract: The invention generally relates to high-throughput label-free enzymatic bioassays using desorption electrospray ionization-mass spectrometry (DESI-MS).
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公开(公告)号：US12068148B2
公开(公告)日：2024-08-20
申请号：US18130474
申请日：2023-04-04
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Brett M. Marsh
CPC classification number: H01J49/24 , H01J49/0031 , H01J49/16 , H01J49/4225
Abstract: The invention generally relates to mass spectrometers that utilize ionic wind and methods of use thereof.
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公开(公告)号：US20240186133A1
公开(公告)日：2024-06-06
申请号：US18520974
申请日：2023-11-28
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Zane Baird , Wen-Ping Peng
CPC classification number: H01J49/067 , H01J49/06 , H01J49/10 , H01J49/165 , H01J49/26
Abstract: The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.
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Patent Agency Ranking
公开(公告)号：US20240170273A1
公开(公告)日：2024-05-23
申请号：US18527974
申请日：2023-12-04
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Zane Baird , Pu Wei
IPC: H01J49/24 , G01N27/622 , G01N27/623 , H01J49/00 , H01J49/06 , H01J49/14
CPC classification number: H01J49/24 , G01N27/622 , G01N27/623 , H01J49/0013 , H01J49/061 , H01J49/142
Abstract: A rigid hull with a flat bottom is covered on the underside by a membrane or sail that is held taut and flush during flight mode for improved aerodynamics with conventional landing gear behind it that is attached to a rail or ski with hinges such that when the landing gear is deployed, the ski presses into the membrane, approximately forming the shape of a boat hull for maritime situations and soft landing especially.
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公开(公告)号：US11984311B2
公开(公告)日：2024-05-14
申请号：US17284144
申请日：2019-10-08
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Dalton Snyder
CPC classification number: H01J49/4225 , G01N33/6848 , H01J49/025 , H01J49/429
Abstract: The invention generally relates to mass spectrometry via frequency tagging.
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公开(公告)号：US20240025861A1
公开(公告)日：2024-01-25
申请号：US18367032
申请日：2023-09-12
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Pallab Basuri , Nicolás M. Morato , Thalappil Pradeep
IPC: C07D235/08
CPC classification number: C07D235/08
Abstract: The invention generally relates to methods of coupling a carbon containing moiety to an amine containing moiety.
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公开(公告)号：US11867684B2
公开(公告)日：2024-01-09
申请号：US17584100
申请日：2022-01-25
Applicant: Purdue Research Foundation
Inventor： Zheng Ouyang , He Wang , Nicholas E. Manicke , Robert Graham Cooks , Qian Yang , Jiangjiang Liu
CPC classification number: G01N33/492 , G01N1/28 , G01N1/286 , G01N33/48714 , G01N33/48785 , G01N33/491 , H01J49/0009 , H01J49/0027 , H01J49/16 , G01N1/10 , G01N2001/2893
Abstract: The invention generally relates to a sample dispenser including an internal standard and methods of use thereof.
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公开(公告)号：US11699580B2
公开(公告)日：2023-07-11
申请号：US16930388
申请日：2020-07-16
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Guangtao Li , Guangming Huang , Jason Duncan , Xin Li , Ewa Sokol , Xin Yan
CPC classification number: H01J49/04 , G01N27/62 , H01J49/0018 , H01J49/0031 , H01J49/045 , H01J49/0445 , H01J49/4205 , Y10T436/24
Abstract: The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a system for analyzing a sample that includes a mass spectrometry probe that generates sample ions, a discontinuous atmospheric interface, and a mass analyzer, in which the system is configured such that ion formation is synchronized with cycling of the discontinuous atmospheric interface.
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