公开(公告)号：US09050611B2

公开(公告)日：2015-06-09

申请号：US13768239

申请日：2013-02-15

Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA

Inventor： David Y. H. Pui ,  Da-Ren Chen

IPC: B05B5/025 ,  B05B5/03 ,  B05B1/14 ,  B05B5/08 ,  B05B7/04 ,  B05B7/06 ,  A61F2/86 ,  B05B13/06

CPC classification number: B05B5/032 ,  A61F2/86 ,  B05B1/14 ,  B05B5/025 ,  B05B5/0255 ,  B05B5/08 ,  B05B5/087 ,  B05B7/0408 ,  B05B7/066 ,  B05B13/06

Abstract: Spraying apparatus and methods that employ multiple nozzle structures for producing multiple sprays of particles, e.g., nanoparticles, for various applications, e.g., pharmaceuticals, are provided. For example, an electrospray dispensing device may include a plurality of nozzle structures, wherein each nozzle structure is separated from adjacent nozzle structures by an internozzle distance. Sprays of particles are established from the nozzle structures by creating a nonuniform electrical field between the nozzle structures and an electrode electrically isolated therefrom.

公开(公告)号：US09642694B2

公开(公告)日：2017-05-09

申请号：US14579116

申请日：2014-12-22

Applicant: NANOCOPOEIA, INC. ,  REGENTS OF THE UNIVERSITY OF MINNESOTA

Inventor： Robert A. Hoerr ,  Da-Ren Chen ,  John V. Carlson ,  David Y. H. Pui

IPC: A61F2/06 ,  B05B1/14 ,  B05B1/06 ,  B05B5/025 ,  B05B5/08 ,  B05B7/06 ,  B05D1/04 ,  B05D1/06 ,  C25D21/12 ,  C25D5/00 ,  C25D17/00

CPC classification number: A61F2/06 ,  B05B1/06 ,  B05B1/14 ,  B05B5/025 ,  B05B5/08 ,  B05B7/061 ,  B05D1/04 ,  B05D1/06 ,  C25D5/003 ,  C25D5/006 ,  C25D17/007 ,  C25D21/12

Abstract: Devices to deliver one or more active ingredients for medical treatment may include a body of material presenting a surface including a polymer adapted to be rendered conductive such that one or more layers of electrospray particles are formable thereon or a body of conductive material presenting a surface upon which one or more layers of electrospray particles are formable thereon. A coating formed of electrospray particles may be deposited to adhere on the surface of the body of material (e.g., the coating may include one or more layers of coating material, at least one layer of the one or more layers of coating material may include an open matrix coating, the open matrix coating may include one or more active ingredients, the open matrix coating may include one or more polymers and one or more active ingredients, etc.).