公开(公告)号：US10433775B2

公开(公告)日：2019-10-08

申请号：US15182455

申请日：2016-06-14

Applicant: RSP SYSTEMS A/S

Inventor： Morten Henneberg ,  Stefan Ovesen Banke ,  Anders Weber

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1495 ,  G01N21/65

Abstract: A metabolite concentration is measured in vivo using Raman spectroscopy in such a way as to receive at a detector light scattered from the metabolite in interstitial fluid in skin in a measurement location at a depth of from 200-300 μm below the skin surface providing improved retention of correct calibration and transferability of calibration between individual subjects.