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公开(公告)号：US10720754B2
公开(公告)日：2020-07-21
申请号：US16458327
申请日：2019-07-01
Applicant: Redshift Bioanalytics, Inc.
Inventor： Eugene Yi-Shan Ma , Charles McAlister Marshall
Abstract: A tunable laser has a solid state laser medium with optical gain region and generates coherent radiation through a facet. A lens collects the coherent radiation and generates a collimated light beam. An external cavity includes a reflective surface and an optical filter, the reflective surface reflecting the collimated beam back to the lens and laser medium, the optical filter positioned between the reflective surface and the lens and having two surfaces and a thermally tunable optical transmission band within the optical gain region of the laser medium. The optical filter (1) transmits a predominant portion of the collimated beam at a desired wavelength of operation, and (2) specularly reflects a remaining portion of the collimated beam from each surface, the collimated beam being incident on the optical filter such that the reflected collimated beams propagate at a non-zero angle with respect to the incident collimated beam.
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公开(公告)号：US11150180B1
公开(公告)日：2021-10-19
申请号：US16248045
申请日：2019-01-15
Applicant: Redshift Bioanalytics, Inc.
Inventor： Eugene Yi-Shan Ma , Charles McAlister Marshall
Abstract: A microfluidic analyzer includes optical sources and optical detectors, the sources generating optical beams, and a multi-chamber fluid cell mounted for relative movement of the fluid cell and the beams to selectively align fluid chambers with beam paths for obtaining optical-response measurements. The cell is configured to reduce differential optical-response measurement between fluid chambers not attributed to a differential analyte in chamber fluids. A controller (1) generates actuator control signals to produce the relative movement of the fluid cell and beams through a sequence of measurement positions, (2) for each measurement position, obtains a set of detector output values, and (3) applies processing to the detector output values to obtain differential optical-response measurements for characterizing a differential analyte between chamber fluids of the cell.
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公开(公告)号：US20200350743A1
公开(公告)日：2020-11-05
申请号：US16932050
申请日：2020-07-17
Applicant: Redshift Bioanalytics, Inc.
Inventor： Eugene Yi-Shan Ma , Charles McAlister Marshall
Abstract: A tunable laser has a solid state laser medium with optical gain region and generates coherent radiation through a facet. A lens collects the coherent radiation and generates a collimated light beam. An external cavity includes a reflective surface and an optical filter, the reflective surface reflecting the collimated beam back to the lens and laser medium, the optical filter positioned between the reflective surface and the lens and having two surfaces and a thermally tunable optical transmission band within the optical gain region of the laser medium. The optical filter (1) transmits a predominant portion of the collimated beam at a desired wavelength of operation, and (2) specularly reflects a remaining portion of the collimated beam from each surface, the collimated beam being incident on the optical filter such that the reflected collimated beams propagate at a non-zero angle with respect to the incident collimated beam.
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Patent Agency Ranking
公开(公告)号：US20190326728A1
公开(公告)日：2019-10-24
申请号：US16458327
申请日：2019-07-01
Applicant: Redshift Bioanalytics, Inc.
Inventor： Eugene Yi-Shan Ma , Charles McAlister Marshall
Abstract: A tunable laser has a solid state laser medium with optical gain region and generates coherent radiation through a facet. A lens collects the coherent radiation and generates a collimated light beam. An external cavity includes a reflective surface and an optical filter, the reflective surface reflecting the collimated beam back to the lens and laser medium, the optical filter positioned between the reflective surface and the lens and having two surfaces and a thermally tunable optical transmission band within the optical gain region of the laser medium. The optical filter (1) transmits a predominant portion of the collimated beam at a desired wavelength of operation, and (2) specularly reflects a remaining portion of the collimated beam from each surface, the collimated beam being incident on the optical filter such that the reflected collimated beams propagate at a non-zero angle with respect to the incident collimated beam.
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公开(公告)号：US10348053B2
公开(公告)日：2019-07-09
申请号：US15647839
申请日：2017-07-12
Applicant: Redshift Bioanalytics, Inc.
Inventor： Eugene Yi-Shan Ma , Charles M. Marshall
Abstract: A tunable laser has a solid state laser medium having an optical gain region and generates coherent radiation through a facet. A lens collects the coherent radiation and generates a collimated light beam. Components of an external cavity include a reflective surface and an optical filter, the reflective surface reflecting the collimated beam back to the lens and the laser medium, the optical filter positioned between the reflective surface and the lens and having two surfaces with a thermally tunable optical transmission band within the optical gain region of the laser medium. The optical filter (1) transmits a predominant portion of the collimated beam at a desired wavelength of operation, and (2) specularly reflects a remaining portion of the collimated beam from each surface, the collimated beam being incident on the optical filter such that the reflected collimated beams propagate at a non-zero angle with respect to the incident collimated beam.
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公开(公告)号：US20170317470A1
公开(公告)日：2017-11-02
申请号：US15647839
申请日：2017-07-12
Applicant: Redshift Bioanalytics, Inc.
Inventor： Eugene Yi-Shan Ma , Charles M. Marshall
CPC classification number: H01S5/068 , B82Y20/00 , G02B5/288 , H01S3/1062 , H01S5/02446 , H01S5/028 , H01S5/141 , H01S5/3401
Abstract: A tunable laser has a solid state laser medium having an optical gain region and generates coherent radiation through a facet. A lens collects the coherent radiation and generates a collimated light beam. Components of an external cavity include a reflective surface and an optical filter, the reflective surface reflecting the collimated beam back to the lens and the laser medium, the optical filter positioned between the reflective surface and the lens and having two surfaces with a thermally tunable optical transmission band within the optical gain region of the laser medium. The optical filter (1) transmits a predominant portion of the collimated beam at a desired wavelength of operation, and (2) specularly reflects a remaining portion of the collimated beam from each surface, the collimated beam being incident on the optical filter such that the reflected collimated beams propagate at a non-zero angle with respect to the incident collimated beam.
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公开(公告)号：US11283236B2
公开(公告)日：2022-03-22
申请号：US16932050
申请日：2020-07-17
Applicant: Redshift Bioanalytics, Inc.
Inventor： Eugene Yi-Shan Ma , Charles McAlister Marshall
Abstract: A tunable laser has a solid state laser medium with optical gain region and generates coherent radiation through a facet. A lens collects the coherent radiation and generates a collimated light beam. An external cavity includes a reflective surface and an optical filter, the reflective surface reflecting the collimated beam back to the lens and laser medium, the optical filter positioned between the reflective surface and the lens and having two surfaces and a thermally tunable optical transmission band within the optical gain region of the laser medium. The optical filter (1) transmits a predominant portion of the collimated beam at a desired wavelength of operation, and (2) specularly reflects a remaining portion of the collimated beam from each surface, the collimated beam being incident on the optical filter such that the reflected collimated beams propagate at a non-zero angle with respect to the incident collimated beam.
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公开(公告)号：US20180059005A1
公开(公告)日：2018-03-01
申请号：US15605962
申请日：2017-05-26
Applicant: Redshift Bioanalytics, Inc.
Inventor： Charles McAlister Marshall , Donald Kuehl , Eugene Yi-Shan Ma , Richard C. Sharp
CPC classification number: G01N21/1717 , G01N21/05 , G01N21/27 , G01N21/39 , G01N30/6095 , G01N30/74 , G01N2021/0353 , G01N2021/1723 , G01N2021/399 , G01N2030/027
Abstract: A fluid analyzer for analysis of analyte bearing fluids includes an optical source and an optical transducer defining a beam path of an optical beam; a fluid flow cell with a fluid channel, wherein an interrogation region is defined in which the optical beam interacts with the fluids resulting in transducer output signals; and a controller configured and operative to control operation of the fluid analyzer. In one example the fluid analyzer is controlled to (1) combine a third fluid with the first or second fluid, (2) conduct the first fluid and second fluid through the interrogation region in first and second intervals respectively, (3) measure the transducer output signals during the first and second time intervals, and (4) determine, from the transducer output signals measurement, values of the first and second fluids and an indication of a physical property of the first fluid.
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