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公开(公告)号：US20210154684A1
公开(公告)日：2021-05-27
申请号：US16953868
申请日：2020-11-20
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Claudio Cherubini , Andreas Drechsler
Abstract: A bucket insert for use in a centrifuge is disclosed. The bucket insert comprises an insert body, the insert body comprising a plurality of elongated receptacles for receiving elongated sample vessels. The bucket insert is configured for orienting the elongated sample vessels in a tilted orientation. In the tilted orientation, at least some of the elongated sample vessels are oriented in a non-parallel fashion.
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公开(公告)号：US10436685B2
公开(公告)日：2019-10-08
申请号：US15417858
申请日：2017-01-27
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Claudio Cherubini , Martin Kopp , Nenad Milicevic , Daniel Mueller , Emad Sarofim , Goran Savatic
IPC: G01N1/40 , G01N15/04 , G01N35/00 , G01N35/10 , B01L3/00 , B04B11/04 , B04B13/00 , B04B5/04 , B04B7/08 , C12M1/00
Abstract: A method for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion having a top opening for receiving the liquid comprising the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion having a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion having a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.
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公开(公告)号：US20180010990A1
公开(公告)日：2018-01-11
申请号：US15417858
申请日：2017-01-27
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Claudio Cherubini , Martin Kopp , Nenad Milicevic , Daniel Mueller , Emad Sarofim , Goran Savatic
IPC: G01N1/40 , B04B5/04 , B04B7/08 , B01L3/00 , G01N35/10 , G01N35/00 , G01N15/04 , B04B13/00 , B04B11/04
CPC classification number: G01N1/4077 , B01L3/5021 , B01L2300/0848 , B01L2300/0858 , B01L2300/168 , B01L2400/086 , B04B5/0407 , B04B7/08 , B04B11/04 , B04B13/00 , C12M47/02 , G01N1/405 , G01N15/042 , G01N35/00584 , G01N35/10 , G01N2001/4083 , G01N2015/045 , Y10T436/111666 , Y10T436/25375
Abstract: A method for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion comprising a top opening for receiving the liquid comprising the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion comprising a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion comprising a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.
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公开(公告)号：US12253535B2
公开(公告)日：2025-03-18
申请号：US17328214
申请日：2021-05-24
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Claudio Cherubini , Andreas Drechsler , Reto Huesser , Ivan Heinzer
Abstract: A module for an automated laboratory system is disclosed. The module comprises a module connector configured to releasably connect to a component of the automated laboratory system, a detector at least configured to detect at least one component marker located at the component so as to obtain position data of the module indicating an actual position of the module, a processor configured to calculate a position deviation of the module from a target position defined by the component based on the position data and to calculate position alignment data based on the position deviation, and a alignment device configured to align the module to the target position based on the position alignment data. Further, an automated laboratory system and a method for aligning a module are disclosed.
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公开(公告)号：US20200033240A1
公开(公告)日：2020-01-30
申请号：US16542786
申请日：2019-08-16
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Claudio Cherubini , Martin Kopp , Nenad Milicevic , Daniel Mueller , Emad Sarofim , Goran Savatic
IPC: G01N1/40 , B01L3/00 , C12M1/00 , B04B5/04 , B04B7/08 , B04B11/04 , B04B13/00 , G01N15/04 , G01N35/00 , G01N35/10
Abstract: A method and system for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion having a top opening for receiving the liquid comprising the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion having a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion having a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.
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Patent Agency Ranking
公开(公告)号：US11890623B2
公开(公告)日：2024-02-06
申请号：US16953868
申请日：2020-11-20
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Claudio Cherubini , Andreas Drechsler
CPC classification number: B04B7/12 , B04B5/0421
Abstract: A bucket insert for use in a centrifuge is disclosed. The bucket insert comprises an insert body, the insert body comprising a plurality of elongated receptacles for receiving elongated sample vessels. The bucket insert is configured for orienting the elongated sample vessels in a tilted orientation. In the tilted orientation, at least some of the elongated sample vessels are oriented in a non-parallel fashion.
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公开(公告)号：US20220203350A1
公开(公告)日：2022-06-30
申请号：US17699872
申请日：2022-03-21
Inventor： Ertan Ergezen , Stephen Conroy , Rijk Oosterbroek , Claudio Cherubini
Abstract: The disclosure features methods, fluid delivery platforms, and apparatus for preparing a sample on a substrate that includes a substrate handler configured to move a substrate between a first position and a second position, and a platform positioned so that when the substrate is in the second position, the platform faces the substrate, where the platform includes a fluid delivery area having a second surface formed from a hydrophilic material for which a water contact angle is 40 degrees or less, and a first surface facing the substrate when the substrate is in the second position, formed from a hydrophobic material for which a water contact angle is 100 degrees or more.
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公开(公告)号：US11278883B2
公开(公告)日：2022-03-22
申请号：US16474942
申请日：2017-12-29
Inventor： Ertan Ergezen , Stephen Conroy , Rijk Edwin Oosterbroek , Claudio Cherubini
Abstract: The disclosure features methods, fluid delivery platforms, and apparatus for preparing a sample on a substrate that includes a substrate handler configured to move a substrate between a first position and a second position, and a platform positioned so that when the substrate is in the second position, the platform faces the substrate, where the platform includes a fluid delivery area having a second surface formed from a hydrophilic material for which a water contact angle is 40 degrees or less, and a first surface facing the substrate when the substrate is in the second position, formed from a hydrophobic material for which a water contact angle is 100 degrees or more.
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公开(公告)号：US11169061B2
公开(公告)日：2021-11-09
申请号：US16542786
申请日：2019-08-16
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Claudio Cherubini , Martin Kopp , Nenad Milicevic , Daniel Mueller , Emad Sarofim , Goran Savatic
IPC: G01N1/40 , G01N15/04 , G01N35/00 , G01N35/10 , B01L3/00 , C12M1/00 , B04B5/04 , B04B7/08 , B04B11/04 , B04B13/00
Abstract: A method and system for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion having a top opening for receiving the liquid containing the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion having a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion having a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.
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公开(公告)号：US20170101272A1
公开(公告)日：2017-04-13
申请号：US15276148
申请日：2016-09-26
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Claudio Cherubini , Andreas Drechsler , Reto Huesser , Nenad Milicevic , Gottlieb Schacher
CPC classification number: B65G33/04 , B65G33/06 , B65G2201/0261 , G01N35/04 , G01N2035/0406 , G01N2035/0465 , G01N2035/0487
Abstract: A conveyor device for conveying test tube holders in a laboratory distribution system is presented. The conveyor device is a screw conveyor device comprising a helical track having a helix axis and a drive shaft having an axis of rotation parallel or coaxial to the helix axis, which drive shaft is adapted to be driven to rotate about the axis of rotation for causing a movement of one test tube holder or a plurality of test tube holders contacting the helical track between an entry region and an exit region. The entry region and the exit region are spaced in a direction of the helix axis. A laboratory distribution system for conveying test tube holders and a laboratory automation system comprising a laboratory distribution system are also presented.
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