公开(公告)号：US10662452B2

公开(公告)日：2020-05-26

申请号：US16083510

申请日：2016-12-15

Applicant: SOUTH CHINA UNIVERSITY OF TECHNOLOGY

Inventor： Ning Li ,  Yanmei Li ,  Minhua Zong

IPC: C12P17/04 ,  C12R1/645

Abstract: A yeast strain and a method for the synthesis of 2,5-dihydroxymethylfuran using this strain are disclosed. The yeast strain is Meyerozyma guilliermondii SC 1103, which has been maintained in the China Center for Type Culture Collection (CCTCC, Wuhan, P.R. China) with an access No. of M2016144. The method for the synthesis of 2,5-dihydroxymethylfuran using this strain is described as follows: after pre-cultivation and cultivation, Meyerozyma guilliermondii SC 1103 cells are added into the buffer solutions containing 5-hydroxymethylfurfural and glucose; the biocatalytic reaction is conducted under designated conditions, thus affording 2,5-dihydroxymethylfuran. This disclosure has many advantages such as good selectivity, mild reaction conditions, environmental friendliness, high efficiency, and good yield.

公开(公告)号：US12280426B2

公开(公告)日：2025-04-22

申请号：US17768925

申请日：2020-10-29

Applicant: South China University of Technology ,  Huazhong University of Technology ,  Jilin University

Inventor： Yuanyuan Li ,  Chao Yang ,  Xuan Luo ,  Dongdong Li ,  Yanguo Qin ,  Ning Li

IPC: B22F10/28 ,  B22F9/08 ,  B22F10/32 ,  B22F10/36 ,  B22F10/366 ,  B22F10/38 ,  B22F12/17

Abstract: The present invention relates to a Si-containing high-strength and low-modulus medical titanium alloy, and an additive manufacturing method and use thereof. The additive manufacturing method comprises alloy ingredient design, powder preparation, model construction and substrate preheating, and additive manufacturing molding; wherein the Si-containing high-strength and low-modulus medical titanium alloy is designed in the ingredient proportion of Ti 60-70 at. %, Nb 16-24 at. %, Zr 4-14 at. %, Ta 1-8 at. %, Si 0.1-5 at. %. The principle of the present invention is design of a medical β-type titanium alloy having high-strength and low-modulus and good biocompatibility by using d-electron theory; reducing the difference of thermal expansion between the silicide and the β-Ti phase by preheating, and at the same time, ensuring that there is a sufficient degree of cooling in the additive manufacturing process to promote the transition of the alloy from the divorced eutectic reaction to the precipitation reaction, thereby solving the common problems, such as the deterioration of mechanical properties caused by the continuous distribution of the Si-containing phase along the grain boundary and the cracking caused by the difference of thermal expansion coefficient between different phases.

公开(公告)号：US20240100598A1

公开(公告)日：2024-03-28

申请号：US17768925

申请日：2020-10-29

Applicant: South China University of Technology ,  Huazhong University of Science and Technology ,  Jilin University

Inventor： Yuanyuan Li ,  Chao Yang ,  Xuan Luo ,  Dongdong Li ,  Yanguo Qin ,  Ning Li

IPC: B22F10/28 ,  B22F9/08 ,  B22F10/366

CPC classification number: B22F10/28 ,  B22F9/08 ,  B22F10/366 ,  B22F2009/0808 ,  B22F2301/205

Abstract: The present invention relates to a Si-containing high-strength and low-modulus medical titanium alloy, and an additive manufacturing method and use thereof. The additive manufacturing method comprises alloy ingredient design, powder preparation, model construction and substrate preheating, and additive manufacturing molding; wherein the Si-containing high-strength and low-modulus medical titanium alloy is designed in the ingredient proportion of Ti 60-70 at. %, Nb 16-24 at. %, Zr 4-14 at. %, Ta 1-8 at. %, Si 0.1-5 at. %. The principle of the present invention is design of a medical β-type titanium alloy having high-strength and low-modulus and good biocompatibility by using d-electron theory; reducing the difference of thermal expansion between the silicide and the β-Ti phase by preheating, and at the same time, ensuring that there is a sufficient degree of cooling in the additive manufacturing process to promote the transition of the alloy from the divorced eutectic reaction to the precipitation reaction, thereby solving the common problems, such as the deterioration of mechanical properties caused by the continuous distribution of the Si-containing phase along the grain boundary and the cracking caused by the difference of thermal expansion coefficient between different phases.

公开(公告)号：US11034986B1

公开(公告)日：2021-06-15

申请号：US16634307

申请日：2017-12-14

Applicant: SOUTH CHINA UNIVERSITY OF TECHNOLOGY

Inventor： Ning Li ,  Xueying Zhang ,  Minhua Zong

IPC: C12N1/20 ,  C12P17/04

Abstract: The present invention provides a Comamonas testosteroni strain and use thereof for the synthesis of 5-hydroxymethyl-2-furancarboxylic acid, wherein the strain is Comamonas testosteroni SC1588, maintained in China Center for Type Culture Collection, CCTCC for short, on Oct. 13, 2016, with an accession number of CCTCC NO: M 2016562.