公开(公告)号：US20160193388A1

公开(公告)日：2016-07-07

申请号：US15070073

申请日：2016-03-15

Applicant: SRI INTERNATIONAL ,  The Board of Trustees of the Leland Stanford Junior University

Inventor： Jose P. Joseph ,  Pablo E. Garcia ,  Karen F. Shakespear ,  Sarah Young ,  Janus A.J. Haagensen ,  Sanjeev Dutta

IPC: A61L29/06 ,  A61M25/00 ,  A61L29/12 ,  A61L29/04 ,  A61L29/02

CPC classification number: A61L29/06 ,  A61L2/03 ,  A61L29/02 ,  A61L29/04 ,  A61L29/041 ,  A61L29/126 ,  A61L29/14 ,  A61L2202/11 ,  A61L2202/24 ,  A61L2400/18 ,  A61M25/0017 ,  A61M25/0045 ,  A61M2025/0019 ,  A61M2025/0056 ,  A61N1/205

Abstract: An implantable catheter is provided that may be disinfected without removal from the body of a patient, using an electrochemical method to generate an electric field on the catheter surface and thus destroy microorganisms in a biofilm that is present or forming. A catheter system includes the implantable catheter and a voltage source that is operably connected to electrodes on or embedded in the exterior and optionally the interior catheter surface. Methods are also provided for disinfecting the implantable catheter in vivo and for detecting or confirming the presence of a pathogenic biofilm thereon.

公开(公告)号：US20170196488A1

公开(公告)日：2017-07-13

申请号：US15468105

申请日：2017-03-23

Applicant: SRI INTERNATIONAL

Inventor： Jonathan Hofius ,  Jose P. Joseph ,  Manish Kothari ,  Pablo E. Garcia Kilroy

IPC: A61B5/1486 ,  A61B5/00 ,  A61B5/145

CPC classification number: A61B5/1486 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/6852

Abstract: Devices, systems and methods for measuring, and configured to measure, a blood analyte continuously or at intervals, the device comprising at least a first set of analyte sensing sensor electrodes configured for making electrochemical measurements of the analyte, and at least a second set of biofouling prevention electrodes in operable proximity to, and configured to prevent biofouling of, the first set of electrodes.

公开(公告)号：US09381276B1

公开(公告)日：2016-07-05

申请号：US15070073

申请日：2016-03-15

Applicant: SRI INTERNATIONAL ,  The Board of Trustees of the Leland Stanford Junior University

Inventor： Jose P. Joseph ,  Pablo E. Garcia ,  Karen F. Shakespear ,  Sarah Young ,  Janus A. J. Haagensen ,  Sanjeev Dutta

IPC: A61L29/06 ,  A61L29/04 ,  A61L29/02 ,  A61L29/12 ,  A61M25/00

CPC classification number: A61L29/06 ,  A61L2/03 ,  A61L29/02 ,  A61L29/04 ,  A61L29/041 ,  A61L29/126 ,  A61L29/14 ,  A61L2202/11 ,  A61L2202/24 ,  A61L2400/18 ,  A61M25/0017 ,  A61M25/0045 ,  A61M2025/0019 ,  A61M2025/0056 ,  A61N1/205

Abstract: An implantable catheter is provided that may be disinfected without removal from the body of a patient, using an electrochemical method to generate an electric field on the catheter surface and thus destroy microorganisms in a biofilm that is present or forming. A catheter system includes the implantable catheter and a voltage source that is operably connected to electrodes on or embedded in the exterior and optionally the interior catheter surface. Methods are also provided for disinfecting the implantable catheter in vivo and for detecting or confirming the presence of a pathogenic biofilm thereon.

公开(公告)号：US10861627B2

公开(公告)日：2020-12-08

申请号：US15565344

申请日：2016-04-20

Applicant: SRI INTERNATIONAL

Inventor： Ronald E. Pelrine ,  Annjoe Wong-Foy ,  Allen L. Hsu ,  Jose P. Joseph

IPC: H01F7/02 ,  H01F7/06 ,  A61B10/02 ,  A61M25/01 ,  B60L13/04

Abstract: A microrobot assembly system includes a substrate containing conductive traces formed into at least one holding zone and one moving zone, a diamagnetic layer on the substrate, at least two magnetic structures movable across the diamagnetic layer in response to voltages applied to the conductive traces, wherein the holding zone holds one of the magnetic structures and the moving zone allows another of the magnetic structures to attach to the magnetic structure being held. The system may include a plate spaced above the substrate and rails to guide the moving magnetic structures.