公开(公告)号：US20240159784A1

公开(公告)日：2024-05-16

申请号：US18389930

申请日：2023-12-20

Applicant: SRI International

Inventor： Nathan Collins ,  Jeremiah Malerich ,  Jason D. White ,  Kevin Luebke ,  Kristina Rucker ,  Brian McCoy

IPC: G01N35/00 ,  B01J19/00 ,  G01N35/04 ,  G01N35/10 ,  G16C10/00 ,  G16C20/10 ,  G16C20/70

CPC classification number: G01N35/00613 ,  B01J19/0046 ,  G01N35/00871 ,  G01N35/04 ,  G01N35/1002 ,  G16C10/00 ,  G16C20/10 ,  G16C20/70 ,  B01J2219/00344 ,  B01J2219/00351 ,  B01J2219/00495 ,  B01J2219/00689 ,  B01J2219/00693 ,  B01J2219/00695 ,  B01J2219/00698 ,  G01N2035/00346 ,  G01N2035/0403 ,  G01N2035/0496

Abstract: Embodiments in accordance with the present disclosure are directed to apparatuses used for reaction screening and optimization purposes. An example apparatus includes a plurality of reaction vessels, a dispensing subsystem, at least one reactor module, an analysis subsystem, an automation subsystem, and control circuitry. The dispensing subsystem delivers reagents to the plurality of reaction vessels for a plurality of reaction mixtures having varied reaction conditions. The at least one reactor module drives a plurality of reactions within the plurality of reaction vessels. The analysis subsystem analyzes compositions contained in the plurality of reaction vessels. The automation subsystem selectively moves the plurality of reaction vessels from a location proximal to the dispensing subsystem to the at least one reactor module based on experimental design parameters. And, the control circuitry identifies optimum reaction conditions for a target end product based on the analysis.

公开(公告)号：US11885822B2

公开(公告)日：2024-01-30

申请号：US16626495

申请日：2018-06-29

Applicant: SRI International

Inventor： Nathan Collins ,  Jeremiah Malerich ,  Jason D. White ,  Kevin Luebke ,  Kristina Rucker ,  Brian McCoy

IPC: G01N35/10 ,  G01N35/00 ,  G01N35/04 ,  B01J19/00 ,  G16C20/10 ,  G16C20/70 ,  G16C10/00

CPC classification number: G01N35/00613 ,  B01J19/0046 ,  G01N35/00871 ,  G01N35/04 ,  G01N35/1002 ,  G16C10/00 ,  G16C20/10 ,  G16C20/70 ,  B01J2219/00344 ,  B01J2219/00351 ,  B01J2219/00495 ,  B01J2219/00689 ,  B01J2219/00693 ,  B01J2219/00695 ,  B01J2219/00698 ,  G01N2035/00346 ,  G01N2035/0403 ,  G01N2035/0496

Abstract: Embodiments in accordance with the present disclosure are directed to apparatuses used for reaction screening and optimization purposes. An example apparatus includes a plurality of reaction vessels, a dispensing subsystem, at least one reactor module, an analysis subsystem, an automation subsystem, and control circuitry. The dispensing subsystem delivers reagents to the plurality of reaction vessels for a plurality of reaction mixtures having varied reaction conditions. The at least one reactor module drives a plurality of reactions within the plurality of reaction vessels. The analysis subsystem analyzes compositions contained in the plurality of reaction vessels. The automation subsystem selectively moves the plurality of reaction vessels from a location proximal to the dispensing subsystem to the at least one reactor module based on experimental design parameters. And, the control circuitry identifies optimum reaction conditions for a target end product based on the analysis.