Abstract:
A method of inducing Parkin expression; inhibiting oxidative stress; and inhibiting cell death of cells by administering deferasirox, hydrocortisone, ketorolac, dexamethasone, and prednisone, a pharmaceutically acceptable salt, stereoisomer, derivative, or solvate thereof to the cell, optionally in a subject, as well as a method of preventing or treating neurodegenerative disease in the subject.
Abstract:
A composition including dapsone for preventing or treating a side effect of a steroid in a subject, and methods for preventing or treating a side effect of a steroid using the composition.
Abstract:
A composition for reducing cell senescence including a Rho-kinase inhibitor and method of treating a cell senescence-related symptom in mammals.
Abstract:
A method of preventing or treating a disease associated with demyelination of a nerve cell in a mammal, a method of promoting remyelination or suppressing demyelination of a nerve cell in a mammal, and a method of reducing expression of PMP22 in a nerve cell of a mammal by administration of 2,5-dihydroxybenzenesulfonic acid or a pharmaceutically acceptable salt or solvate thereof.
Abstract:
A composition including dapsone for preventing or treating a side effect of a steroid in a subject, and methods for preventing or treating a side effect of a steroid using the composition.
Abstract:
A composition for preventing or treating muscular atrophy or promoting muscular regeneration in a subject including a sulfonamide compound, a pharmaceutically acceptable salt, solvate, or polymorph thereof, or a combination of at least two of the foregoing, and a method of preventing or treating muscular atrophy or promoting muscular regeneration by using the composition.
Abstract:
A composition for reducing cell senescence including a Rho-kinase inhibitor and method of treating a cell senescence-related symptom in mammals.
Abstract:
A method of preventing or treating a disease associated with demyelination of a nerve cell in a mammal, a method of promoting remyelination or suppressing demyelination of a nerve cell in a mammal, and a method of reducing expression of PMP22 in a nerve cell of a mammal by administration of 2,5-dihydroxybenzenesulfonic acid or a pharmaceutically acceptable salt or solvate thereof.
Abstract:
Provided is a method of reducing senescence in a cell or subject, or treating or preventing a symptom or disease associated therewith, by administering a BRAF inhibitor to the cell or subject.