公开(公告)号：US12258656B2

公开(公告)日：2025-03-25

申请号：US16624542

申请日：2019-09-30

Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES

Inventor： Guomin Wang ,  Huaiyu Wang ,  Kimho Paul Chu

IPC: C23C22/60 ,  A61L27/04 ,  A61L27/30 ,  A61L27/54 ,  C22C23/00 ,  B82Y5/00

Abstract: The present invention relates to a magnesium alloy material, which is an in situ magnesium hydroxide nanosheet layer modified magnesium alloy. The material is prepared from a magnesium alloy through a hydrothermal reaction under alkaline condition. The protective effect of the in situ formed magnesium hydroxide nanosheet layer structure results in remarkably enhanced corrosion resistance of the magnesium alloy, meanwhile the biocompatibility can also be significantly improved since the release rate of magnesium ion can be significantly reduced. In addition, the two-dimensional nanolayer structure has a non-releasing physical antibacterial property depending on contact. Therefore, the magnesium alloy material according to the present invention has an extremely great application prospect in the field of medical implant.

公开(公告)号：US10336615B2

公开(公告)日：2019-07-02

申请号：US15389666

申请日：2016-12-23

Applicant: Shenzhen Institutes of Advanced Technology

Inventor： Huaiyu Wang ,  Yuetao Zhao ,  Xuefeng Yu

IPC: C01B25/00 ,  A61K41/00 ,  H01L51/00 ,  C07F9/06 ,  C09K15/14 ,  C09K15/28 ,  C07C309/04 ,  C07C309/06 ,  C07C309/29 ,  C07C309/30 ,  C07C309/39 ,  C07C309/40 ,  C07C309/42 ,  C07C309/46 ,  H01L51/05 ,  H01L51/50

Abstract: The present invention provides a titanium ligand-modified black phosphorus and the preparation method and use thereof. The titanium ligand-modified black phosphorus is a complex of black phosphorus and a titanium ligand having a structure represented by formula (I): wherein in the formula (I), R1 comprises C1-C6 alkyl, or phenyl optionally further substituted with 0 to 5 groups each independently selected from halogen atom, C1-C6 alkyl, nitro, hydroxy, amino or C1-C3 alkoxy; the C1-C6 alkyl or C1-C3 alkoxy is optionally further substituted with 0 to 3 groups each independently selected from halogen atom, nitro, hydroxy, amino, methyl, ethyl or n-propyl. The titanium ligand-modified black phosphorus of the present invention is not likely oxidized without changing inherent properties of the black phosphorus, and the antioxidant capacity is greatly enhanced.