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    METHOD AND APPARATUS FOR GUIDING A CATHETER
    1.
    发明申请
    METHOD AND APPARATUS FOR GUIDING A CATHETER 审中-公开
    用于引导导管的方法和装置

    公开(公告)号：US20160058978A1

    公开(公告)日：2016-03-03

    申请号：US14783158

    申请日：2014-04-10

    Applicant: THE CLEVELAND CLINIC FOUNDATION

    Inventor： Samir Kapadia

    IPC: A61M25/09

    CPC classification number: A61M25/09041 ,  A61M25/01 ,  A61M25/09 ,  A61M2025/0063 ,  A61M2025/0177 ,  A61M2025/018 ,  A61M2025/1045

    Abstract: An apparatus (100) for guiding a catheter within a patient's body, the apparatus comprising: a first wire (112) having longitudinally spaced distal and proximal first wire ends (114,116)) separated by a first wire body; a catheter (102) having longitudinally spaced distal and proximal catheter ends (130,132) separated by a catheter body having a catheter lumen (136) extending longitudinally therethrough between the distal and proximal catheter ends, the catheter having a catheter aperture (138) extending substantially laterally through the catheter body at a location proximally adjacent to the distal catheter end; a second wire (120) having longitudinally spaced distal and proximal second wire ends (122,124) separated by a second wire body.

    Abstract translation: 一种用于在患者体内引导导管的装置（100），所述装置包括：第一线（112），其具有由第一线体分开的纵向间隔开的远端和近端的第一线端（114,116）; 导管（102），其具有纵向间隔开的远端和近侧导管末端（130,132），所述远端和近端导管末端（130,132）由具有在所述远端和近端导管末端之间纵向延伸穿过的导管内腔（136）分开的导管主体分开，所述导管具有基本上延伸的导管孔 横向穿过导管主体在靠近远侧导管末端的位置; 第二线（120）具有由第二线体分开的纵向间隔开的远端和近端的第二线端（122,124）。

    APPARATUS AND METHOD FOR TARGETING A BODY TISSUE
    2.
    发明申请
    APPARATUS AND METHOD FOR TARGETING A BODY TISSUE 有权
    装置和方法来达到身体组织

    公开(公告)号：US20150374933A9

    公开(公告)日：2015-12-31

    申请号：US14060274

    申请日：2013-10-22

    Applicant: BAVARIA MEDICAL TECHNOLOGY, CANADA INC. ,  THE CLEVELAND CLINIC FOUNDATION

    Inventor： Samir Kapadia ,  Marwane Berrada ,  Cesar Fuentes-Ortega ,  Daniel Wing Fai Mok

    IPC: A61M5/42

    CPC classification number: A61M5/427 ,  A61B17/3403 ,  A61B17/3478 ,  A61B34/20 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/22069 ,  A61B2017/22095 ,  A61B2017/3405 ,  A61B2017/3411 ,  A61B2017/3488 ,  A61B2018/00279 ,  A61B2018/00351 ,  A61B2018/00357 ,  A61B2018/0038 ,  A61B2018/00386 ,  A61B2034/2051

    Abstract: An apparatus for targeting a desired target site on a body tissue comprising a wall of a first body cavity of a patient includes a target catheter. The framing member, when deployed into an expanded condition, has a framing member body which includes a three-dimensionally bulbous portion defining a maximum body footprint in a lateral dimension and has longitudinally spaced proximal and distal body ends which are both longitudinally spaced from the maximum body footprint. The proximal body end is attached to the target catheter. A protrusion has a diameter which is smaller than the maximum body footprint diameter. At least one target point is carried by the framing member and is adapted for placement adjacent the desired target site. At least one target pathway is attached to at least one target point. At least a portion of the target pathway is substantially spaced apart from the framing member body.

    Abstract translation: 用于靶向包括患者的第一体腔的壁的身体组织上的所需目标部位的装置包括目标导管。 框架构件在展开状态时具有框架构件主体，该框架构件主体包括三维球形部分，其在侧向尺寸上限定最大身体足迹，并且具有纵向间隔开的近端和远侧主体端部， 身体足迹。 近端体端部附接到目标导管。 突起具有比最大身体足迹直径小的直径。 至少一个目标点由框架构件承载，并适于放置在所需目标位置附近。 至少一个目标通路连接至至少一个目标点。 目标通道的至少一部分与框架构件主体基本间隔开。

    APPARATUS AND METHOD FOR TARGETING A BODY TISSUE
    3.
    发明申请
    APPARATUS AND METHOD FOR TARGETING A BODY TISSUE 有权
    装置和方法来达到身体组织

    公开(公告)号：US20140114246A1

    公开(公告)日：2014-04-24

    申请号：US14060274

    申请日：2013-10-22

    Applicant: BAVARIA MEDICAL TECHNOLOGY, CANADA INC. ,  THE CLEVELAND CLINIC FOUNDATION

    Inventor： Samir Kapadia ,  Marwane Berrada ,  Cesar Fuentes-Ortega ,  Daniel Wing Fai Mok

    IPC: A61M5/42

    CPC classification number: A61M5/427 ,  A61B17/3403 ,  A61B17/3478 ,  A61B34/20 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/22069 ,  A61B2017/22095 ,  A61B2017/3405 ,  A61B2017/3411 ,  A61B2017/3488 ,  A61B2018/00279 ,  A61B2018/00351 ,  A61B2018/00357 ,  A61B2018/0038 ,  A61B2018/00386 ,  A61B2034/2051

    Abstract: An apparatus for targeting a desired target site on a body tissue comprising a wall of a first body cavity of a patient includes a target catheter. The framing member, when deployed into an expanded condition, has a framing member body which includes a three-dimensionally bulbous portion defining a maximum body footprint in a lateral dimension and has longitudinally spaced proximal and distal body ends which are both longitudinally spaced from the maximum body footprint. The proximal body end is attached to the target catheter. A protrusion has a diameter which is smaller than the maximum body footprint diameter. At least one target point is carried by the framing member and is adapted for placement adjacent the desired target site. At least one target pathway is attached to at least one target point. At least a portion of the target pathway is substantially spaced apart from the framing member body.

    Abstract translation: 用于靶向包括患者的第一体腔的壁的身体组织上的所需目标部位的装置包括目标导管。 框架构件在展开状态时具有框架构件主体，该框架构件主体包括三维球形部分，其在侧向尺寸上限定最大身体足迹，并且具有纵向间隔开的近端和远侧主体端部， 身体足迹。 近端体端部附接到目标导管。 突起具有比最大身体足迹直径小的直径。 至少一个目标点由框架构件承载，并适于放置在所需目标位置附近。 至少一个目标通路连接至至少一个目标点。 目标通道的至少一部分与框架构件主体基本间隔开。

    SYSTEMS AND METHODS FOR TREATING A REGURGITANT HEART VALVE
    5.
    发明申请
    SYSTEMS AND METHODS FOR TREATING A REGURGITANT HEART VALVE 审中-公开

    公开(公告)号：US20180243087A1

    公开(公告)日：2018-08-30

    申请号：US15968000

    申请日：2018-05-01

    Applicant: THE CLEVELAND CLINIC FOUNDATION

    Inventor： Samir Kapadia

    IPC: A61F2/24 ,  A61M29/02

    Abstract: A system for treating regurgitation of blood through a diseased heart valve having at least two leaflets can include an implantable, lollipop-shaped device and an adjustment mechanism. The device can have a proximal end portion, a distal end portion, and an intermediate portion extending therebetween. The intermediate portion can include an expandable occluding member having a selectively adjustable diameter and a biocompatible layer attached to at least a portion thereof. The distal end portion can include an anchoring member. The adjustment member can include a distal connecting end that is operatively connected to the proximal end portion of the device. Operation of the adjustment member, after implantation of the device, can cause the diameter of the occluding member to change so that at least one of the heart leaflet coapts with a portion of the occluding member to mitigate or prevent regurgitation of blood through the diseased heart valve.

    APPARATUS, SYSTEM, AND METHOD FOR TREATING A REGURGITANT HEART VALVE
    7.
    发明申请
    APPARATUS, SYSTEM, AND METHOD FOR TREATING A REGURGITANT HEART VALVE 审中-公开

    公开(公告)号：US20160030166A1

    公开(公告)日：2016-02-04

    申请号：US14883819

    申请日：2015-10-15

    Applicant: THE CLEVELAND CLINIC FOUNDATION

    Inventor： Samir Kapadia

    IPC: A61F2/24

    CPC classification number: A61F2/246 ,  A61F2/2466 ,  A61F2250/0004 ,  A61F2250/001 ,  A61M29/02

    Abstract: An apparatus for treating regurgitation of blood through a diseased heart valve having at least two leaflets includes a lollipop-shaped body member having a proximal end portion, a distal end portion, and an intermediate portion extending between the end portions. The intermediate portion includes an expandable occluding member having an adjustable diameter so that, during at least a portion of the cardiac cycle, at least one of the heart leaflet coapts with a portion of the occluding member to mitigate or prevent regurgitation of blood through the diseased heart valve. The proximal end portion is physically connected to the occluding member and includes a connecting mechanism for operably mating with an adjustment member for adjusting the position and diameter of the occluding member within the diseased heart valve. The distal end portion includes an anchoring member for securing the apparatus in a heart chamber containing the diseased heart valve.

    Apparatuses and methods for at least partially supporting a valve leaflet of a regurgitant heart valve
    8.
    发明授权
    Apparatuses and methods for at least partially supporting a valve leaflet of a regurgitant heart valve 有权

    公开(公告)号：US11241313B2

    公开(公告)日：2022-02-08

    申请号：US16712059

    申请日：2019-12-12

    Applicant: THE CLEVELAND CLINIC FOUNDATION

    Inventor： Jose L. Navia ,  Samir Kapadia ,  Marwane Berrada

    IPC: A61F2/24

    Abstract: An apparatus for partially supporting a leaflet of a regurgitant heart valve comprises at least one subvalvular device including a subvalvular supporting portion including a leaflet-contacting upper supporter surface longitudinally spaced from an oppositely facing lower supporter surface. A supporter perimeter wall extends longitudinally between the upper and lower supporter surfaces, with at least a portion contacting a subvalvular cardiac wall adjacent to the heart valve. An anchor portion is adjacent to, and longitudinally spaced from, the upper supporter surface. The anchor portion includes a leaflet-contacting lower anchor surface longitudinally spaced from an oppositely facing upper anchor surface. A connector neck is interposed longitudinally between, and is directly attached to both of, the upper supporter surface and the lower anchor surface. The connector neck penetrates longitudinally through at least one of a base of the leaflet and an annulus of the heart valve at a manufactured puncture site.

    Method and apparatus for guiding a catheter
    9.
    发明授权
    Method and apparatus for guiding a catheter 有权

    公开(公告)号：US10213584B2

    公开(公告)日：2019-02-26

    申请号：US14783158

    申请日：2014-04-10

    Applicant: THE CLEVELAND CLINIC FOUNDATION

    Inventor： Samir Kapadia

    IPC: A61M25/01 ,  A61M25/09 ,  A61M25/10 ,  A61M25/00

    Abstract: An apparatus (100) for guiding a catheter within a patient's body, the apparatus comprising: a first wire (112) having longitudinally spaced distal and proximal first wire ends (114,116)) separated by a first wire body; a catheter (102) having longitudinally spaced distal and proximal catheter ends (130,132) separated by a catheter body having a catheter lumen (136) extending longitudinally therethrough between the distal and proximal catheter ends, the catheter having a catheter aperture (138) extending substantially laterally through the catheter body at a location proximally adjacent to the distal catheter end; a second wire (120) having longitudinally spaced distal and proximal second wire ends (122,124) separated by a second wire body.

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