-
公开(公告)号：US10366872B2
公开(公告)日：2019-07-30
申请号：US16264023
申请日：2019-01-31
Applicant: The Trustees of Indiana University
Inventor： Martin F. Jarrold , Deven L. Shinholt , Staci N. Anthony , Andrew W. Alexander
Abstract: A quadrupole mass filter and method for operating the filter are described. Sample ions, each having a mass-to-charge ratio, are passed to a quadrupole at least one AC voltage is applied thereto to separate the ions by incrementally varying a frequency of the at least one AC voltage within a first range of frequencies and, for each of at least some of the incremental frequencies in the first range of frequencies, incrementally varying an amplitude of the at least one AC voltage within a range of amplitudes, wherein each incremental frequency and incremental amplitude pair of the at least one AC voltage creates a different band pass filter in the quadrupole through which produced ions having a different corresponding mass-to-charge ratio pass to a detector.
-
公开(公告)号：US20210407782A1
公开(公告)日：2021-12-30
申请号：US17468841
申请日：2021-09-08
Applicant: THE TRUSTEES OF INDIANA UNIVERSITY
Inventor： Martin F. Jarrold , Andrew W. Alexander , Aaron R. Todd
Abstract: A CDMS may include an ELIT having a charge detection cylinder (CD), a charge generator for generating a high frequency charge (HFC), a charge sensitive preamplifier (CP) having an input coupled to the CD and an output configured to produce a charge detection signal (CHD) in response to a charge induced on the CD, and a processor configured to (a) control the charge generator to induce an HFC on the CD, (b) control operation of the ELIT to cause a trapped ion to oscillate back and forth through the CD each time inducing a charge thereon, and (c) process CHD to (i) determine a gain factor as a function of the HFC induced on the CD, and (ii) modify a magnitude of the portion of CHD resulting from the charge induced on the CD by the trapped ion passing therethrough as a function of the gain factor.
-
Patent Agency Ranking
公开(公告)号：US20190164739A1
公开(公告)日：2019-05-30
申请号：US16264023
申请日：2019-01-31
Applicant: The Trustees of Indiana University
Inventor： Martin F. Jarrold , Deven L. Shinholt , Staci N. Anthony , Andrew W. Alexander
CPC classification number: H01J49/4215 , H01J49/0031 , H01J49/427
Abstract: A quadrupole mass filter and method for operating the filter are described. Sample ions, each having a mass-to-charge ratio, are passed to a quadrupole at least one AC voltage is applied thereto to separate the ions by incrementally varying a frequency of the at least one AC voltage within a first range of frequencies and, for each of at least some of the incremental frequencies in the first range of frequencies, incrementally varying an amplitude of the at least one AC voltage within a range of amplitudes, wherein each incremental frequency and incremental amplitude pair of the at least one AC voltage creates a different band pass filter in the quadrupole through which produced ions having a different corresponding mass-to-charge ratio pass to a detector.
-
公开(公告)号：US11862448B2
公开(公告)日：2024-01-02
申请号：US18149743
申请日：2023-01-04
Applicant: THE TRUSTEES OF INDIANA UNIVERSITY
Inventor： Martin F. Jarrold , Andrew W. Alexander , Aaron R. Todd
CPC classification number: H01J49/025 , H01J49/0009 , H01J49/022 , H01J49/4245
Abstract: A CDMS may include an ion source to generate ions from a sample, a mass spectrometer to separate the generated ions as a function of ion mass-to-charge ratio, an electrostatic linear ion trap (ELIT) having a charge detection cylinder disposed between first and second ion mirrors, wherein ions exiting the mass spectrometer are supplied to the ELIT, a charge generator for generating free charges, a field free region between the charge generator and the charge detection cylinder, and a processor configured to control the charge generator, with no ions in the charge detection cylinder, to generate a target number of free charges and cause the target number of free charges to travel across the field-free region and into contact with the charge detection cylinder to deposit the target number of free charges thereon and thereby calibrate or reset the charge detection cylinder to a corresponding target charge level.
-
5.发明公开公开(公告)号：US20230154736A1
公开(公告)日：2023-05-18
申请号：US18149743
申请日：2023-01-04
Applicant: THE TRUSTEES OF INDIANA UNIVERSITY
Inventor： Martin F. Jarrold , Andrew W. Alexander , Aaron R. Todd
CPC classification number: H01J49/025 , H01J49/0009 , H01J49/022 , H01J49/4245
Abstract: A CDMS may include an ion source to generate ions from a sample, a mass spectrometer to separate the generated ions as a function of ion mass-to-charge ratio, an electrostatic linear ion trap (ELIT) having a charge detection cylinder disposed between first and second ion mirrors, wherein ions exiting the mass spectrometer are supplied to the ELIT, a charge generator for generating free charges, a field free region between the charge generator and the charge detection cylinder, and a processor configured to control the charge generator, with no ions in the charge detection cylinder, to generate a target number of free charges and cause the target number of free charges to travel across the field-free region and into contact with the charge detection cylinder to deposit the target number of free charges thereon and thereby calibrate or reset the charge detection cylinder to a corresponding target charge level.
-
公开(公告)号：US11594405B2
公开(公告)日：2023-02-28
申请号：US17468841
申请日：2021-09-08
Applicant: THE TRUSTEES OF INDIANA UNIVERSITY
Inventor： Martin F. Jarrold , Andrew W. Alexander , Aaron R. Todd
Abstract: A CDMS may include an ELIT having a charge detection cylinder (CD), a charge generator for generating a high frequency charge (HFC), a charge sensitive preamplifier (CP) having an input coupled to the CD and an output configured to produce a charge detection signal (CHD) in response to a charge induced on the CD, and a processor configured to (a) control the charge generator to induce an HFC on the CD, (b) control operation of the ELIT to cause a trapped ion to oscillate back and forth through the CD each time inducing a charge thereon, and (c) process CHD to (i) determine a gain factor as a function of the HFC induced on the CD, and (ii) modify a magnitude of the portion of CHD resulting from the charge induced on the CD by the trapped ion passing therethrough as a function of the gain factor.
-
公开(公告)号：US11177122B2
公开(公告)日：2021-11-16
申请号：US17058553
申请日：2019-06-04
Applicant: THE TRUSTEES OF INDIANA UNIVERSITY
Inventor： Martin F. Jarrold , Andrew W. Alexander , Aaron R. Todd
Abstract: A CDMS may include an ELIT having a charge detection cylinder (CD), a charge generator for generating a high frequency charge (HFC), a charge sensitive preamplifier (CP) having an input coupled to the CD and an output configured to produce a charge detection signal (CHD) in response to a charge induced on the CD, and a processor configured to (a) control the charge generator to induce an HFC on the CD, (b) control operation of the ELIT to cause a trapped ion to oscillate back and forth through the CD each time inducing a charge thereon, and (c) process CHD to (i) determine a gain factor as a function of the HFC induced on the CD, and (ii) modify a magnitude of the portion of CHD resulting from the charge induced on the CD by the trapped ion passing therethrough as a function of the gain factor.
-
-
-
-
-
-
Search Results
7
records
(took 0.018 seconds)
