Method and apparatus for determining a chromatogram

    公开(公告)号:US10184920B2

    公开(公告)日:2019-01-22

    申请号:US15123558

    申请日:2014-03-04

    Applicant: TOFWERK AG

    Abstract: The invention relates to a method and an apparatus for determining a chromatogram. The method includes a first step where a sample is inserted in two separation columns (2.1, 2.2, 2.3), wherein for each separation column (2.1, 2.2, 2.3), a corresponding part of the sample is inserted in the respective separation column (2.1, 2.2, 2.3) with a corresponding insertion device (3.1, 3.2, 3.3) which is controlled by a corresponding modulation function for generating a corresponding modulated part of the sample in the respective separation column (2.1, 2.2, 2.3), wherein the modulation functions with which the parts of the sample are modulated in the separation columns (2.1, 2.2, 2.3) differ from each other. Furthermore, the method includes a second step where each modulated part of the sample is guided through the respective separation column (2.1, 2.2, 2.3), a third step where a signal of each modulated part of the sample is measured with a same detector (4) after having passed the respective separation column (2.1, 2.2, 2.3), and a fourth step where for each separation column (2.1, 2.2, 2.3), a correlation of the signal and the modulation function with which the corresponding part of the sample is modulated in the respective separation column (2.1, 2.2, 2.3) is calculated in order to determine the chromatogram of the respective separation column (2.1, 2.2, 2.3).

    METHOD AND APPARATUS FOR DETERMINING A MOBILITY OF IONS
    2.
    发明申请
    METHOD AND APPARATUS FOR DETERMINING A MOBILITY OF IONS 有权
    用于确定离子的移动性的方法和装置

    公开(公告)号:US20160320341A1

    公开(公告)日:2016-11-03

    申请号:US15178941

    申请日:2016-06-10

    Applicant: Tofwerk AG

    CPC classification number: G01N27/622 H01J49/02 H01J49/061 H01J49/40

    Abstract: A method and an apparatus for determining a mobility of ions. The method includes the steps of modulating an ion beam with an ion gate which is controlled by a modulation function for generating a modulated ion beam, of guiding the modulated ion beam through a drifting region, of measuring a signal of the modulated ion beam after the modulated ion beam has passed the drifting region and of calculating a correlation of the modulation function and the signal in order to determine the mobility of the ions. The apparatus includes the ion gate, the drifting region through which the modulated ion beam is guidable, a detector by which the signal of the modulated ion beam is measurable after the modulated ion beam has passed the drifting region and a calculation unit by which the correlation of the modulation function and the signal is calculable in order to determine the mobility of the ions. An autocorrelation of the modulation function is a two-valued function.

    Abstract translation: 用于确定离子迁移率的方法和装置。 该方法包括以下步骤:用离子门调制离子束,该离子门由用于产生调制离子束的调制功能控制,该调制离子束将经调制的离子束引导通过漂移区,测量经过调制离子束的信号 调制离子束已经通过漂移区域并且计算调制函数和信号的相关性,以便确定离子的迁移率。 该装置包括离子门,经调制的离子束可引导的漂移区域,经调制的离子束已经通过漂移区域之后可测量调制的离子束的信号的检测器,以及计算单元, 的调制函数和信号是可计算的,以便确定离子的迁移率。 调制函数的自相关是一个二值函数。

    Method and apparatus for determining a mobility of ions

    公开(公告)号:US09671369B2

    公开(公告)日:2017-06-06

    申请号:US15178941

    申请日:2016-06-10

    Applicant: Tofwerk AG

    CPC classification number: G01N27/622 H01J49/02 H01J49/061 H01J49/40

    Abstract: A method and an apparatus for determining a mobility of ions. The method includes the steps of modulating an ion beam with an ion gate which is controlled by a modulation function for generating a modulated ion beam, of guiding the modulated ion beam through a drifting region, of measuring a signal of the modulated ion beam after the modulated ion beam has passed the drifting region and of calculating a correlation of the modulation function and the signal in order to determine the mobility of the ions. The apparatus includes the ion gate, the drifting region through which the modulated ion beam is guidable, a detector by which the signal of the modulated ion beam is measurable after the modulated ion beam has passed the drifting region and a calculation unit by which the correlation of the modulation function and the signal is calculable in order to determine the mobility of the ions. An autocorrelation of the modulation function is a two-valued function.

    METHOD AND APPARATUS FOR DETERMINING THE SIZE OF AEROSOL PARTICLES
    4.
    发明申请
    METHOD AND APPARATUS FOR DETERMINING THE SIZE OF AEROSOL PARTICLES 有权
    用于测定气溶胶颗粒大小的方法和装置

    公开(公告)号:US20150211974A1

    公开(公告)日:2015-07-30

    申请号:US14419779

    申请日:2013-06-12

    Applicant: Tofwerk AG

    Abstract: A method and an apparatus for determining an aerosol particle size distribution that includes the steps of modulating an aerosol particle beam with an aerosol particle gate which is controlled by a modulation function for generating a modulated aerosol particle beam, guiding the modulated aerosol particle beam through a drifting region, measuring a signal of the modulated aerosol particle beam after the modulated aerosol particle beam has passed the drifting region and calculating a correlation of the modulation function and the signal in order to determine the size distribution of the aerosol particles.

    Abstract translation: 一种用于确定气溶胶颗粒尺寸分布的方法和装置,包括以下步骤:用气溶胶颗粒栅调制气溶胶粒子束,该气溶胶颗粒栅由用于产生调制气溶胶粒子束的调制功能控制,将经调制的气溶胶粒子束引导通过 漂移区域,测量经调制的气溶胶粒子束已经通过漂移区域后调制的气溶胶颗粒束的信号,并计算调制函数和信号的相关性,以确定气溶胶颗粒的尺寸分布。

    Method and apparatus for determining the size of aerosol particles
    5.
    发明授权
    Method and apparatus for determining the size of aerosol particles 有权
    用于确定气溶胶颗粒尺寸的方法和装置

    公开(公告)号:US09588031B2

    公开(公告)日:2017-03-07

    申请号:US14419779

    申请日:2013-06-12

    Applicant: Tofwerk AG

    Abstract: A method and an apparatus for determining an aerosol particle size distribution that includes the steps of modulating an aerosol particle beam with an aerosol particle gate which is controlled by a modulation function for generating a modulated aerosol particle beam, guiding the modulated aerosol particle beam through a drifting region, measuring a signal of the modulated aerosol particle beam after the modulated aerosol particle beam has passed the drifting region and calculating a correlation of the modulation function and the signal in order to determine the size distribution of the aerosol particles.

    Abstract translation: 一种用于确定气溶胶颗粒尺寸分布的方法和装置,包括以下步骤:用气溶胶颗粒栅调制气溶胶粒子束,该气溶胶颗粒栅由用于产生调制气溶胶粒子束的调制功能控制,将经调制的气溶胶粒子束引导通过 漂移区域,测量经调制的气溶胶粒子束已经通过漂移区域后调制的气溶胶颗粒束的信号,并计算调制函数和信号的相关性,以确定气溶胶颗粒的尺寸分布。

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