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    Optical material and method for modifying the refractive index
    2.
    发明授权
    Optical material and method for modifying the refractive index 有权

    公开(公告)号：US10806567B2

    公开(公告)日：2020-10-20

    申请号：US15923443

    申请日：2018-03-16

    Applicant: University of Rochester

    Inventor： Wayne H. Knox ,  Li Ding ,  Jay Friedrich Kunzler ,  Dharmendra M. Jani

    IPC: A61F2/16 ,  A61F9/008 ,  G02C7/04

    Abstract: A method for modifying the refractive index of an optical, polymeric material. The method comprises irradiating select regions of the optical, polymeric material with a focused, visible or near-IR laser having a pulse energy from 0.05 nJ to 1000 nJ. The irradiation results in the formation of refractive optical structures, which exhibit little or no scattering loss. The method can he used to modify the refractive index of an intraocular lens following the surgical implantation of the intraocular lens in a human eye. The invention is also directed to an optical device comprising refractive optical structures, which exhibit little or no scattering loss and are characterized by a positive change in refractive index.

    Method for modifying the refractive index of an optical material and resulting optical vision component
    3.
    发明授权
    Method for modifying the refractive index of an optical material and resulting optical vision component 有权

    公开(公告)号：US10649115B2

    公开(公告)日：2020-05-12

    申请号：US15946287

    申请日：2018-04-05

    Applicant: University of Rochester

    Inventor： Wayne H. Knox ,  Dharmendra Jani ,  Li Ding

    IPC: B29D11/00 ,  G02B3/00 ,  A61F9/008 ,  A61L27/16 ,  A61L27/50 ,  A61L27/52 ,  A61F2/16

    Abstract: A method for modifying the refractive index of an optical polymeric material. The method comprises continuously irradiating predetermined regions of an optical, polymeric material with femtosecond laser pulses to form a gradient index refractive structure within the material. The optical polymeric material can include a photosensitizer to increase the photoefficiency of the two-photo process resulting in the formation of the observed refractive structures. An optical device includes an optical, polymeric lens material having an anterior surface and posterior surface and an optical axis intersecting the surfaces and at least one laser-modified, GRIN layer disposed between the anterior surface and the posterior surface and arranged along a first axis 45° to 90° to the optical axis. The at least one laser-modified GRIN layer comprises a plurality of adjacent refractive segments characterized by a variation in index of refraction across at least one of at least a portion of the adjacent segments and along each segment.

    Method for modifying the refractive index of ocular tissues
    7.
    发明授权
    Method for modifying the refractive index of ocular tissues 有权
    改变眼组织折射率的方法

    公开(公告)号：US08512320B1

    公开(公告)日：2013-08-20

    申请号：US13789755

    申请日：2013-03-08

    Applicant: University of Rochester ,  Bausch & Lomb Incorporated

    Inventor： Wayne H. Knox ,  Krystel R. Huxlin ,  Jay F. Kunzler ,  Li Ding

    IPC: A61B18/18

    CPC classification number: A61F9/00804 ,  A61F9/008 ,  A61F9/00829 ,  A61F2009/00842 ,  A61F2009/00848 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/0088

    Abstract: The invention is directed to a method for correcting vision in a patient by modifying the refractive index of cornea tissue. The method comprises identifying and measuring the degree of vision correction of the patient; and determining the position and type of refractive structures to be written into the cornea tissue of the patient to correct the patient's vision. The refractive structures are written by irradiating select regions of the cornea tissue with focused laser pulses having a wavelength from 400 nm to 900 nm and a pulse energy from 0.01 nJ to 10 nJ. The refractive structures are characterized by a positive change in refractive index in relation to non-irradiated cornea tissue of the patient.

    Abstract translation: 本发明涉及通过改变角膜组织的折射率来校正患者视力的方法。 该方法包括识别和测量患者的视力矫正程度; 以及确定要写入患者的角膜组织中的折射结构的位置和类型以校正患者的视力。 通过用波长为400nm至900nm的聚焦激光脉冲和0.01nJ至10nJ的脉冲能量照射角膜组织的选择区域来写入折射结构。 折射结构的特征在于与患者的未照射的角膜组织相关的折射率的正变化。

    Method for Modifying the Refractive Index of Ocular Tissues
    10.
    发明申请
    Method for Modifying the Refractive Index of Ocular Tissues 审中-公开

    公开(公告)号：US20190046357A1

    公开(公告)日：2019-02-14

    申请号：US16163175

    申请日：2018-10-17

    Applicant: University of Rochester

    Inventor： Wayne H. Knox ,  Krystel R. Huxlin ,  Jay F. Kunzler ,  Li Ding

    IPC: A61F9/008

    Abstract: A laser system for changing the index of refraction of cornea tissue in a living eye. The laser system comprises a laser that provides laser pulses with a wavelength from 400 nm to 900 nm and a pulse energy from 0.01 nJ to 10 nJ, and a control device for setting the operating parameters of the laser below an optical breakdown threshold of the tissue to avoid photo-disruption and tissue destruction of the tissue, and to direct the laser pulses at the cornea tissue resulting in a change in the index of refraction of the tissue within regions irradiated by the laser pulses.

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