公开(公告)号：US20190078985A1

公开(公告)日：2019-03-14

申请号：US16129581

申请日：2018-09-12

Applicant: Worcester Polytechnic Institute

Inventor： Dirk Albrecht ,  Ross Lagoy ,  Kyra Burnett

IPC: G01N1/30 ,  G01N1/44 ,  G01N1/36 ,  G01N33/483

Abstract: Devices and methods for capturing and imaging a specimen, such as a living organism, are disclosed. In some embodiments, a method for imaging a living organism in vivo includes placing at least one specimen into a hydrogel polymer on a substrate, and curing the hydrogel to embed the at least one specimen within the cured hydrogel such that the at least one specimen is kept alive and the movement of the at least one specimen within the cured hydrogel is restricted. The at least one embedded specimen can be imaged.

公开(公告)号：US20190212355A1

公开(公告)日：2019-07-11

申请号：US16240720

申请日：2019-01-05

Applicant: Worcester Polytechnic Institute

Inventor： Dirk Albrecht ,  Ross Lagoy

IPC: G01N35/10 ,  B01L3/00

CPC classification number: G01N35/1072 ,  B01L3/502715 ,  B01L3/502738 ,  B01L2300/0829 ,  G01N35/1011 ,  G01N35/1016 ,  G01N35/1097

Abstract: Systems and methods for delivering fluid to a microfluidic device is provided. The system includes a multi-well plate having a plurality of wells and an inlet tube having a first end being in communication with the one or more wells of the multi-well plate and a second end being in communication with a microfluidic device. The first end of the inlet tube is moveable between the plurality of wells of the multi-well plate to deliver fluid to the microfluidic device from the plurality of wells of the multi-well plate.

公开(公告)号：US11249100B2

公开(公告)日：2022-02-15

申请号：US16240720

申请日：2019-01-05

Applicant: Worcester Polytechnic Institute

Inventor： Dirk Albrecht ,  Ross Lagoy

IPC: B01L3/00 ,  G01N35/10 ,  B01L3/02

Abstract: Systems and methods for delivering fluid to a microfluidic device is provided. The system includes a multi-well plate having a plurality of wells and an inlet tube having a first end being in communication with the one or more wells of the multi-well plate and a second end being in communication with a microfluidic device. The first end of the inlet tube is moveable between the plurality of wells of the multi-well plate to deliver fluid to the microfluidic device from the plurality of wells of the multi-well plate.

公开(公告)号：US11248995B2

公开(公告)日：2022-02-15

申请号：US16129581

申请日：2018-09-12

Applicant: Worcester Polytechnic Institute

Inventor： Dirk Albrecht ,  Ross Lagoy ,  Kyra Burnett

IPC: G01N1/30 ,  G01N1/44 ,  G01N1/36 ,  G01N21/64 ,  G01N33/483

Abstract: Devices and methods for capturing and imaging a specimen, such as a living organism, are disclosed. In some embodiments, a method for imaging a living organism in vivo includes placing at least one specimen into a hydrogel polymer on a substrate, and curing the hydrogel to embed the at least one specimen within the cured hydrogel such that the at least one specimen is kept alive and the movement of the at least one specimen within the cured hydrogel is restricted. The at least one embedded specimen can be imaged.