公开(公告)号：US11920026B2

公开(公告)日：2024-03-05

申请号：US16845636

申请日：2020-04-10

Applicant: i-CoreBio Inc.

Inventor： Jae Ho Shin ,  Ki Hak Gwon

IPC: C08L5/08 ,  A61L31/04 ,  A61L31/14 ,  A61L31/16 ,  D01D1/02 ,  D01D5/00 ,  D01D5/38 ,  B82Y30/00 ,  C08B37/08

CPC classification number: C08L5/08 ,  A61L31/042 ,  A61L31/148 ,  A61L31/16 ,  D01D1/02 ,  D01D5/0015 ,  D01D5/38 ,  A61L2300/114 ,  A61L2400/12 ,  B82Y30/00 ,  C08B37/0072 ,  C08L2201/06 ,  C08L2203/12

Abstract: Disclosed herein is a novel polymer having a structure based on a biodegradable polymer. In the novel polymer, the biodegradable polymer has at least one kind of functional groups from among a hydroxyl group and a carboxyl group, wherein the biodegradable polymer bears a functional group conjugated with a nitric oxide-releasing compound and a different functional group substituted with a photopolymerizable functional group, the nitric oxide-releasing compound comprising a NO donor. Also provided is a nanofiber fabricated from the modified biodegradable polymer. The nanofiber can be fabricated by electrospinning the novel polymer.

公开(公告)号：US20200325307A1

公开(公告)日：2020-10-15

申请号：US16845636

申请日：2020-04-10

Applicant: i-CoreBio Inc.

Inventor： Jae Ho Shin ,  Ki Hak Gwon

IPC: C08L5/08 ,  D01D5/38 ,  D01D5/00 ,  D01D1/02 ,  A61L31/04 ,  A61L31/16 ,  A61L31/14

Abstract: Disclosed herein is a novel polymer having a structure based on a biodegradable polymer. In the novel polymer, the biodegradable polymer has at least one kind of functional groups from among a hydroxyl group and a carboxyl group, wherein the biodegradable polymer bears a functional group conjugated with a nitric oxide-releasing compound and a different functional group substituted with a photopolymerizable functional group, the nitric oxide-releasing compound comprising a NO donor. Also provided is a nanofiber fabricated from the modified biodegradable polymer. The nanofiber can be fabricated by electrospinning the novel polymer.