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    Lactam-based compounds with a urethane or urea functional group, and uses thereof
    2.
    发明授权
    Lactam-based compounds with a urethane or urea functional group, and uses thereof 有权
    具有氨基甲酸酯或脲官能团的基于内酰胺的化合物及其用途

    公开(公告)号：US09334236B2

    公开(公告)日：2016-05-10

    申请号：US13390852

    申请日：2010-08-18

    Applicant: Osama M. Musa

    Inventor： Osama M. Musa

    IPC: C08F126/10 ,  C07D223/10 ,  C08F226/10 ,  C07D207/12 ,  C07D207/27 ,  C08G18/28 ,  C08G18/81

    CPC classification number: C07D207/27 ,  C07D223/10 ,  C08G18/2855 ,  C08G18/8108

    Abstract: Compounds comprising a lactam moiety, and a urethane or urea functional group are presented. By a preferred synthesis route, they are prepared using at least one polymerizable compound comprising an isocyanate moiety and reacting it with at least one hydroxyalkyl lactam compound or one aminoalkyl lactam compound. In preferred embodiments the lactam moiety is a pyrrolidone or caprolactam ring, and the polymerizable compound is a functionalized aryl isocyanate. The compounds and homopolymers and non-homopolymers thereof find useful application in a wide variety of arts, including: adhesive, agricultural, biocides, cleaning, coating, electronics, encapsulation, membrane, microelectronics, oilfield, performance chemical, personal care, sealant, and sensor applications.

    Abstract translation: 提供了包含内酰胺部分和氨基甲酸酯或脲官能团的化合物。 通过优选的合成途径，它们使用至少一种包含异氰酸酯部分的可聚合化合物制备，并使其与至少一种羟烷基内酰胺化合物或一种氨基烷基内酰胺化合物反应。 在优选的实施方案中，内酰胺部分是吡咯烷酮或己内酰胺环，并且可聚合化合物是官能化的芳基异氰酸酯。 化合物及其均聚物和非均聚物可用于广泛的领域，包括：粘合剂，农业，杀生物剂，清洁，涂料，电子，封装，膜，微电子学，油田，性能化学品，个人护理，密封剂和 传感器应用。

    POLYMER-BOUND UV ABSORBERS IN PERSONAL CARE COMPOSITIONS
    7.
    发明申请
    POLYMER-BOUND UV ABSORBERS IN PERSONAL CARE COMPOSITIONS 有权
    聚合物紫外吸收剂在个人护理组合物中的应用

    公开(公告)号：US20150265522A1

    公开(公告)日：2015-09-24

    申请号：US14727558

    申请日：2015-06-01

    Applicant: ISP INVESTMENTS INC.

    Inventor： Osama M. Musa ,  Jenn S. Shih

    IPC: A61K8/81 ,  A61Q19/08 ,  A61Q17/04

    CPC classification number: A61Q17/04 ,  A61K8/8164 ,  A61K2800/57 ,  C08F8/30 ,  C08F222/06

    Abstract: Personal care compositions comprising a polymer-bound UV absorber are described that provide enhanced properties, including customizable UV spectrum protection, broad-spectrum UV spectrum protection, water resistance, and labile UV stabilization. The polymer comprises anhydride functionality, such as maleic anhydride or a derivative thereof, and the UV absorber contains at least one hydroxyl, primary amine, or secondary amine group.The personal care compositions may be used to treat and/or protect against burns, cancers, erythema, lentigo (“liver spots”), keratotic lesions, wrinkles, and cellular changes of the skin; and/or color changes, embrittlement, lack of luster, tangles, split ends, and/or unmanageability of the hair.

    Abstract translation: 描述了包含聚合物结合的UV吸收剂的个人护理组合物，其提供增强的性质，包括可定制的UV光谱保护，广谱紫外光谱保护，耐水性和不稳定的UV稳定性。 聚合物包含酸酐官能团，如马来酸酐或其衍生物，UV吸收剂含有至少一个羟基，伯胺或仲胺基团。 个人护理组合物可用于治疗和/或保护免受灼伤，癌症，红斑，雀斑（“肝斑”），角化病变，皱纹和皮肤的细胞变化; 和/或颜色变化，脆化，缺乏光泽，缠结，分裂末端和/或头发的不可操纵性。

    Peptides involved in the SCF c-Kit signaling pathway and compositions comprising same
    10.
    发明授权
    Peptides involved in the SCF c-Kit signaling pathway and compositions comprising same 有权
    涉及SCF c-Kit信号通路的肽和包含其的组合物

    公开(公告)号：US08962565B2

    公开(公告)日：2015-02-24

    申请号：US13982386

    申请日：2012-01-30

    Applicant: Claude Dal Farra ,  Nouha Domloge ,  Jean-Marie Botto

    Inventor： Claude Dal Farra ,  Nouha Domloge ,  Jean-Marie Botto

    IPC: A61K38/08 ,  A61K8/64 ,  C07K7/06 ,  C07K7/08 ,  A61Q17/04 ,  A61Q19/02 ,  A61Q19/08 ,  C07K5/113 ,  A61Q19/00

    CPC classification number: A61K8/64 ,  A61K38/08 ,  A61Q17/04 ,  A61Q19/004 ,  A61Q19/02 ,  A61Q19/08 ,  C07K5/1021 ,  C07K7/06 ,  C07K7/08

    Abstract: Peptide compounds of general formula (I) R1-(AA)n-X1—X2—X3-Asp-Leu-Lys-Lys-X4—X5-(AA)p-R2, cosmetic or pharmaceutical compositions comprising at least one peptide compound of general formula (I) in a physiologically acceptable medium, and methods for cosmetic treatment of skin are disclosed. The peptide compounds of general formula (I) were demonstrated to be agents making it possible to influence the pigmentation of the skin and skin appendages, by ensuring optimal transfer of the melanosomes to the keratinocytes, so as to make the skin tone uniform owing to an effect on the SCF/c-Kit signaling pathway. The compounds, compositions, and methods treat or attenuate age-related pigmentation defects and the effects of photoaging on the skin.

    Abstract translation: 通式（I）R1-（AA）n-X1-X2-X3-Asp-Leu-Lys-Lys-X4-X5-（AA）p-R2的肽化合物，包含至少一种肽化合物的化妆品或药物组合物 通式（I）的生理学上可接受的介质，以及皮肤美容治疗方法。 证明通式（I）的肽化合物是通过确保黑素体最佳转移到角质形成细胞而使皮肤和皮肤附着物的色素沉着成为可能的原因，从而使肤色均匀 对SCF / c-Kit信号通路的作用。 化合物，组合物和方法治疗或减轻年龄相关色素沉着缺陷和光老化对皮肤的影响。

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