公开(公告)号：US20250087474A1

公开(公告)日：2025-03-13

申请号：US18832984

申请日：2023-01-24

Applicant: DH Technologies Development Pte. Ltd.

Inventor： Sebin CHERIAN ,  William LOYD ,  Pavel RYUMIN

IPC: H01J49/00 ,  H01J49/08

Abstract: Methods and systems for controlling a filament of an electron emitter associated with an ion reaction cell in accordance with various aspects of the present teachings may account for inter-filament and inter-instrument variability and can provide improved reproducibility in EAD experiments and ease of use. In some aspects, a method of operating an ion reaction device of a mass spectrometer system is provided. The method comprises applying a calibration drive voltage to a filament of an electron emitter associated with an ion reaction cell and determining a value representative of the calibration electron emission current generated by the filament while having the calibration drive voltage applied thereto. A calibration saturation voltage can be determined by iteratively increasing the calibration drive voltage applied to the filament and determining the value of the calibration electron emission current at each corresponding calibration drive voltage until the filament reaches a saturation condition.

公开(公告)号：US11971394B2

公开(公告)日：2024-04-30

申请号：US17047606

申请日：2019-04-16

Applicant: SHARP KABUSHIKI KAISHA

Inventor： Shohei Komaru ,  Tadashi Iwamatsu

IPC: G01N30/70 ,  G01N27/66 ,  H01J49/08

CPC classification number: G01N30/70 ,  G01N27/66 ,  H01J49/08

Abstract: The electron capture detector (100) is a device for detecting a sample (α1). The electron capture detector (100) includes a detection cell (1), a sample inlet (2), and an electron emitting element (20). The detection cell (1) forms a reaction chamber (6). The sample inlet (2) introduces a first carrier gas containing the sample (α1) into the reaction chamber (6). The electron emitting element (20) emits electrons (β) into the reaction chamber (6). An ion (α2) derived from the sample component is generated as a result of the electron emitting element (20) emitting electrons (β) into the reaction chamber (6).

公开(公告)号：US11791121B2

公开(公告)日：2023-10-17

申请号：US16868000

申请日：2020-05-06

Applicant: Massachusetts Institute of Technology ,  Instituto Tecnológico y de Estudios Superiores de Monterrey

Inventor： Luis Fernando Velásquez-García ,  Imperio Perales-Martinez

IPC: H01J1/304 ,  H01J49/08 ,  H01J35/06 ,  H01J9/02 ,  F03H1/00

CPC classification number: H01J1/3042 ,  F03H1/0025 ,  H01J9/025 ,  H01J35/064 ,  H01J35/065 ,  H01J49/08

Abstract: A field emission electron source and a method of manufacturing the same. A field emission electron source comprises an emitting electrode and an extractor gate electrode. The emitting electrode comprising a plurality of particles with nanosharp protrusions. The extractor gate electrode comprises a metal. The extractor gate electrode is formed in a same plane as the emitting electrode. The extractor gate electrode is formed surrounding the emitting electrode. A method of manufacturing a field emission electron source comprises forming an emitting electrode comprising a plurality of particles with nanosharp protrusions using a direct ink writing (DIW) printer. The method comprises forming an extractor gate electrode comprising a metal using the DIW printer.

公开(公告)号：US11217437B2

公开(公告)日：2022-01-04

申请号：US16298654

申请日：2019-03-11

Applicant: Agilent Technologies, Inc.

Inventor： Kenneth R. Newton ,  Nigel P. Gore ,  Mark Denning

IPC: H01J49/00 ,  H01J49/06 ,  H01J49/08

Abstract: Electron capture dissociation (ECD) is performed by transmitting an electron beam through a cell along an electron beam axis, generating plasma in the cell by energizing a gas with the electron beam, and transmitting an ion beam through the interaction region along an ion beam axis to produce fragment ions. Generating the plasma forms an interaction region in the cell spaced from and not intersecting the electron beam, and including low-energy electrons effective for ECD. The ion beam axis may be at an angle to and offset from the ion beam axis, such that the electron beam does not intersect the ion beam.

公开(公告)号：US10892153B2

公开(公告)日：2021-01-12

申请号：US16713713

申请日：2019-12-13

Applicant: MKS Instruments, Inc.

Inventor： James E. Blessing ,  Jonathan Leslie ,  Jonathan Hugh Batey

IPC: H01J49/14 ,  H01J49/08

Abstract: Apparatus (e.g., ion source), systems (e.g., residual gas analyzer), and methods provide extended life and improved analytical stability of mass spectrometers in the presence of contamination gases while achieving substantial preferential ionization of sampled gases over internal background gases. One embodiment is an ion source that includes a gas source, nozzle, electron source, and electrodes. The gas source delivers gas via the nozzle to an evacuated ionization volume and is at a higher pressure than that of the evacuated ionization volume. Gas passing through the nozzle freely expands in an ionization region of the ionization volume. The electron source emits electrons through the expanding gas in the ionization region to ionize at least a portion of the expanding gas. The electrodes create electrical fields for ion flow from the ionization region to a mass filter and are located at distances from the nozzle and oriented to limit their exposure to the gas.

公开(公告)号：US10832901B2

公开(公告)日：2020-11-10

申请号：US16424206

申请日：2019-05-28

Applicant: FEI Company

Inventor： Bert Henning Freitag ,  Sorin Lazar ,  Stephan Kujawa ,  Maarten Kuijper ,  Gerard Nicolaas Anne van Veen ,  Peter Christiaan Tiemeijer ,  Jamie McCormack

IPC: H01J49/44 ,  H01J49/00 ,  H01J49/02 ,  H01J49/08

Abstract: A method of performing Electron Energy-Loss Spectroscopy (EELS) in an electron microscope, comprising: Producing a beam of electrons from a source; Using an illuminator to direct said beam so as to irradiate the specimen; Using an imaging system to receive a flux of electrons transmitted through the specimen and direct it onto a spectroscopic apparatus comprising: A dispersion device, for dispersing said flux in a dispersion direction so as to form an EELS spectrum; and A detector, comprising a detection surface that is sub-divided into a plurality of detection zones, specifically comprising: Using at least a first detection zone, a second detection zone and a third detection zone to register a plurality of EELS spectral entities; and Reading out said first and said second detection zones whilst said third detection zone is registering one of said plurality of EELS spectral entities.

公开(公告)号：US20200328071A1

公开(公告)日：2020-10-15

申请号：US16814036

申请日：2020-03-10

Applicant: SHIMADZU CORPORATION

Inventor： Osamu FURUHASHI ,  Tomomi TAMURA ,  Kiyoshi OGAWA

IPC: H01J49/08 ,  H01J49/04

Abstract: A mass spectrometer, includes: a sampling probe that irradiates a specimen disposed in the atmosphere with an electron and obtains a sample separated from the specimen; and a measurement unit that performs mass spectrometry of the sample obtained by the sampling probe, wherein the sampling probe comprises: a casing having an opening which is opened to the atmosphere and an outlet through which the sample is discharged to the measurement unit; and a surface emission type electron emission element housed in the casing such that an electron emission surface thereof opposes to the opening.

公开(公告)号：US10388506B2

公开(公告)日：2019-08-20

申请号：US15321563

申请日：2015-12-04

Applicant: Korea Basic Science Institute

Inventor： Mo Yang ,  Seung Yong Kim ,  Hyun Sik Kim ,  Wan Seop Jeong

IPC: H01J49/40 ,  H01J49/08 ,  H01J49/14 ,  H01J43/10 ,  H01J43/24

Abstract: Provided is a time-of-flight mass spectrometer including: an ionization part receiving electron beams to thereby emit ions; a cold electron supply part injecting the electron beams to the ionization part; an ion detection part detecting the ions emitted from the ionization part; and an ion separation part connecting the ionization part and the ion detection part, wherein the cold electron supply part includes a microchannel plate receiving ultraviolet rays to thereby emit the electron beams, the ions emitted from the ionization part pass through the ion separation part to thereby reach the ion detection part, and the ion separation part has a straight tube shape.

公开(公告)号：US09305760B2

公开(公告)日：2016-04-05

申请号：US14420545

申请日：2013-08-15

Applicant: State of Oregon acting by and through the State board of higher education on behalf of OSU

Inventor： Douglas F. Barofsky ,  Valery G. Voinov ,  Joseph S. Beckman

IPC: H01J49/40 ,  H01J49/14 ,  H01J49/08 ,  H01J49/26

CPC classification number: H01J49/147 ,  H01J49/0054 ,  H01J49/062 ,  H01J49/08 ,  H01J49/26

Abstract: An electron source for electron-induced dissociation in an RF-free electromagnetostatic cell for use installation in a tandem mass spectrometer is provided. An electromagnetostatic electron-induced dissociation cell may include at least one magnet having an opening disposed therein and having a longitudinal axis extending through the opening, the magnet having magnetic flux lines associated therewith, and an electron emitter having an electron emissive surface comprising a sheet, the emitter disposed about the axis at a location relative to the magnet where the electron emissive surface is substantially perpendicular to the magnetic flux lines at the electron emissive surface.

Abstract translation: 提供了一种用于无串联电磁静电电池中电子诱导解离的电子源，用于串联质谱仪中的安装。 电磁静电电子诱导解离单元可以包括至少一个具有设置在其中的开口的磁体，并且具有延伸穿过该开口的纵向轴线，该磁体具有与之相关联的磁通线，以及具有包括片材的电子发射表面的电子发射器， 所述发射极围绕所述轴设置在相对于所述磁体的位置处，其中所述电子发射表面基本上垂直于所述电子发射表面处的磁通线。

公开(公告)号：US20150162174A1

公开(公告)日：2015-06-11

申请号：US14552303

申请日：2014-11-24

Applicant: PERKINELMER HEALTH SCIENCES, INC.

Inventor： Hamid Badiei ,  Steven A. Beres

IPC: H01J49/00 ,  H01J49/08 ,  H01J49/26 ,  H01J49/02

CPC classification number: H01J43/18 ,  H01J49/0009 ,  H01J49/025

Abstract: Certain embodiments described herein are directed to detectors and systems using them. In some examples, the detector can include a plurality of dynodes, in which one or more of the dynodes are coupled to an electrometer. In some instances, an analog signal from a non-saturated dynode is measured and cross-calibrated with a pulse count signal to extend the dynamic range of the detector.

Abstract translation: 本文描述的某些实施例涉及使用它们的检测器和系统。 在一些示例中，检测器可以包括多个倍增电极，其中一个或多个倍增电极耦合到静电计。 在一些情况下，测量来自非饱和倍增极的模拟信号并用脉冲计数信号进行交叉校准，以扩展检测器的动态范围。