目标物种
61. SW15 GENE AS A DIAGNOSTIC TARGET FOR THE IDENTIFICATION OF FUNGAL AND YEAST SPECIES
申请号: PCT/EP2009057346
申请日: 2009-06-15
公开（公告）号: WO2009150244A1
公开（公告）日: 2009-12-17
发明人: BARRY THOMAS GERARD; MAHER MAJELLA; SMITH TERRY JAMES; JANKIEWICZ MARCIN; O'CONNOR LOUISE; TUITE NINA; LAHIFF SINEAD
The invention relates to the SWI5 gene, the corresponding RNA, specific probes, primers and oligonucleotides related thereto and their use in diagnostic assays to detect and/ or discriminate between fungal and yeast species.
更多62. A SENSOR FOR DETECTION OF A TARGET SPECIES AND METHOD OF FORMING THE SAME
申请号: PCT/GB2017/050282
申请日: 2017-02-03
公开（公告）号: WO2017134461A1
公开（公告）日: 2017-08-10
发明人: BEHRENDT, Jonathan; TYLER, Sarah
A sensor for detection of a target species is provided. The sensor includes a capture layer on an organic semi-conductor to which biomolecules may be bound. The capture layer polymer is deposited from a non-aqueous solution and the polymer is insoluble in water and has reactive groups for interaction with the analyte directly or via a conjugated species. Organic electronic devices, for example organic thin-film transistors having the capture layer are also provided. Use of a capture layer provides a low cost high quality biosensor which may be reliably produced in large quantities.
更多63. ACE2 AS A TARGET GENE FOR THE MOLECULAR IDENTIFICATION OF YEAST AND FUNGAL SPECIES
申请号: PCT/EP2009/057344
申请日: 2009-06-15
公开（公告）号: WO2009150243A1
公开（公告）日: 2009-12-17
发明人: BARRY, Thomas Gerard; SMITH, Terry James; MAHER, Majella; JANKIEWICZ, Marcin; O'CONNOR, Louise; TUITE, Nina; LAHIFF, Sinead
The present invention relates to nucleic acid primers and probes for use in the identification of one or more yeast species. More specifically the invention relates to the Ace2 gene, the corresponding RNA, specific probes, primers and oligonucleotides related thereto and their use in diagnostic assays to detect and / or discriminate between yeast species.
更多64. EIF2γ GENE AS A DIAGNOSTIC TARGET FOR THE IDENTIFICATION OF FUNGAL AND YEAST SPECIES
申请号: PCT/EP2009/057337
申请日: 2009-06-15
公开（公告）号: WO2009150241A2
公开（公告）日: 2009-12-17
发明人: BARRY, Thomas Gerard; MAHER, Majella; SMTH, Terry James; MARCIN, Jankiewicz; O'CONNOR, Louise; TUITE, Nina; LAHIFF, Sinead
The current invention relates to a diagnostic kit for a yeast or fungal species comprising at least one oligonucleotide probe capable of binding to at least a portion of the eIF2y gene or its corresponding mRNA.
更多65. SYSTEM FOR DETECTING BASIC TARGET SPECIES IN A FUEL COMPOSITION
申请号: PCT/EP2007/061706
申请日: 2007-10-30
公开（公告）号: WO2008052997A1
公开（公告）日: 2008-05-08
发明人: MALPAS, Richard Edward; MCFARLANE, Elaine; READING, Keith; WARDLE, Robert Wilfred Matthews
Method for detecting a basic target species in a fuel composition, by (i) adding a spectroscopically active indicator which is capable of reacting with the target species, and (ii) detecting the spectroscopic response (suitably a colour change) of the fuel composition to the presence of the indicator. The method may be used to detect an additive such as a detergent or dispersant additive, in particular in an automotive gasoline or diesel fuel or a lubricating oil. Also provided is a kit for carrying out the method, in particular in the field. The indicator may be a phenolphthalein indicator such as tetrabromophenolphthalein ethyl ester (HTBPE).
更多66. EIF2 GAMMA GENE AS A DIAGNOSTIC TARGET FOR THE IDENTIFICATION OF FUNGAL AND YEAST SPECIES
申请号: PCT/EP2009057337
申请日: 2009-06-15
公开（公告）号: WO2009150241A3
公开（公告）日: 2010-04-08
发明人: BARRY THOMAS GERARD; MAHER MAJELLA; SMTH TERRY JAMES; MARCIN JANKIEWICZ; O'CONNOR LOUISE; TUITE NINA; LAHIFF SINEAD
The current invention relates to a diagnostic kit for a yeast or fungal species comprising at least one oligonucleotide probe capable of binding to at least a portion of the eIF2y gene or its corresponding mRNA.
更多67. METHODS FOR ESTABLISHING THRESHOLD LIMITS FOR A CHEMICAL OR BIOLOGICAL AGENT IN A TARGET SPECIES
申请号: PCT/US2016/035678
申请日: 2016-06-03
公开（公告）号: WO2016196902A1
公开（公告）日: 2016-12-08
发明人: COYNE, Shawn T.; COYNE, Kevin P.
Methods are provided for establishing a threshold exposure limit to a chemical or biological agent for the members of a target species taking into account the potential for variation in responses among the members of that species. Exemplary exposures include maximum safe exposure to a toxic agent, or minimum effective dose for a pharmaceutical. The method is particularly useful under circumstances wherein variation in responsiveness to the agent cannot be ascertained by directly exposing members of the target species to the agent.
更多68. LepA/Guf1 gene sequences as a diagnostic target for the identification of bacterial species
申请号: US12999052
申请日: 2009-06-15
公开（公告）号: US09243298B2
公开（公告）日: 2016-01-26
发明人: Thomas Gerard Barry; Majella Maher; Terence James Smith; Justin O'Grady
The current invention relates to a diagnostic kit for a bacterial species and/or fungal and/or yeast species comprising at least one oligonucleotide probe capable of binding to at least a portion of the LepA and/or Guf1 genes or its corresponding mRNA.
更多69. Temperature swing adsorption process for the separation of target species from a gas mixture
申请号: US13406079
申请日: 2012-02-27
公开（公告）号: US08784533B2
公开（公告）日: 2014-07-22
发明人: Daniel P. Leta; Preeti Kamakoti; Harry W. Deckman; Peter I. Ravikovitch; Thomas N. Anderson
A temperature swing adsorption process for the removal of a target species, such as an acid gas, from a gas mixture, such as a natural gas stream. Herein, a novel multi-step temperature swing/pressure swing adsorption is utilized to operate while maintaining very high purity levels of contaminant removal from a product stream. The present process is particularly effective and beneficial in removing contaminants such as CO2 and/or H2S from a natural gas at relatively high adsorption pressures (e.g., at least 500 psig) to create product streams of very high purity (i.e., very low contaminant levels).
更多70. LEPA/GUF1 GENE SEQUENCES AS A DIAGNOSTIC TARGET FOR THE IDENTIFICATION OF BACTERIAL SPECIES
申请号: US12999052
申请日: 2009-06-15
公开（公告）号: US20110217704A1
公开（公告）日: 2011-09-08
发明人: Thomas Gerard Barry; Majella Maher; Terence James Smith; Justin O'Grady
The current invention relates to a diagnostic kit for a bacterial species and/or fungal and/or yeast species comprising at least one oligonucleotide probe capable of binding to at least a portion of the LepA and/or Guf1 genes or its corresponding mRNA.
更多71. APPARATUS AND PROCESS FOR SENSING TARGET GAS SPECIES IN SEMICONDUCTOR PROCESSING SYSTEMS
申请号: PCT/US2005001409
申请日: 2005-01-14
公开（公告）号: WO2005072161A3
公开（公告）日: 2005-12-29
发明人: CHEN PHILIP S H; CHEN ING-SHIN; DIMEO FRANK JR; NEUNER JEFFREY W; WELCH JAMES; ROEDER JEFFREY F
A gas detector and process for detecting a target gas species, such as a fluorine-containing species in a gas containing same, e.g., an effluent of a semiconductor processing tool undergoing etch cleaning with HF, NF3, etc. The gas detector in one aspect employs a nickel-containing filament that is sensitive to the fluorine-containing species, which can function both as a sensing component and as a heat source when elevated temperature sensing is required. The gas detector in one aspect employs an elongated gas sensor element that can be vertically mounted on a support structure. Vertical mounting of such elongated gas sensor element on the support structure significantly improves the signal strength, reduces the response time, minimizes the footprint of the gas detector, and provides structural flexibility for accommodating thermal expansion/contraction of such gas sensor element.
更多72. TEMPERATURE SWING ADSORPTION PROCESS FOR THE SEPARATION OF TARGET SPECIES FROM A GAS MIXTURE
申请号: PCT/US2012/026745
申请日: 2012-02-27
公开（公告）号: WO2012118737A2
公开（公告）日: 2012-09-07
发明人: LETA, Daniel, P.; KAMAKOTI, Preeti; DECKMAN, Harry, W.; RAVIKOVITCH, Peter, I.; ANDERSON, Thomas, N.
A temperature swing adsorption process for the removal of a target species, such as an acid gas, from a gas mixture, such as a natural gas stream. Herein, a novel multi-step temperature swing/pressure swing adsorption is utilized to operate while maintaining very high purity levels of contaminant removal from a produc t stream. The present process is particularly effective and beneficial in removing contaminants such as C02 and/or H2 S from a natural gas at relatively high adsorption pressures (e.g., at least 500 psig) to create product streams of very high purity (i.e., very low contaminant levels).
更多73. Detection of target species in a sample or liquid flow using diodes and an electrical signal
申请号: US372902
申请日: 1995-01-17
公开（公告）号: US5514601A
公开（公告）日: 1996-05-07
发明人: Paul J. Reilly
A method of and apparatus for the presence of a target species in a sample taken from or consisting of a mixture of species, comprising the steps of introducing one or more electrical diodes into the mixture prior to taking the sample from the mixture, in such a manner that the presence of diodes in the sample is dependent on the presence of the target species in the sample; passing an alternating electrical signal having a known waveform through the sample; and detecting the modification of the waveform of the signal emerging from the sample due to the presence of the diode or diodes in the sample.
更多74. TEMPERATURE SWING ADSORPTION PROCESS FOR THE SEPARATION OF TARGET SPECIES FROM A GAS MIXTURE
申请号: PCT/US2012026745
申请日: 2012-02-27
公开（公告）号: WO2012118737A3
公开（公告）日: 2012-11-22
发明人: LETA DANIEL P; KAMAKOTI PREETI; DECKMAN HARRY W; RAVIKOVITCH PETER I; ANDERSON THOMAS N
A temperature swing adsorption process for the removal of a target species, such as an acid gas, from a gas mixture, such as a natural gas stream. Herein, a novel multi-step temperature swing/pressure swing adsorption is utilized to operate while maintaining very high purity levels of contaminant removal from a produc t stream. The present process is particularly effective and beneficial in removing contaminants such as C02 and/or H2 S from a natural gas at relatively high adsorption pressures (e.g., at least 500 psig) to create product streams of very high purity (i.e., very low contaminant levels).
更多75. METHODS OF IDENTIFYING COMPOUNDS THAT BIND TO TARGET SPECIES UNDER ISOTHERMAL DENATURING CONDITIONS
申请号: PCT/US2000/042677
申请日: 2000-12-07
公开（公告）号: WO01046693A2
公开（公告）日: 2001-06-28
发明人:
A high throughput screening method for identifying a compound that binds to a target species. The method includes: incubating a plurality of test mixtures under isothermal denaturing conditions, each test mixture including at least one test compound and at least one target species, wherein the isothermal denaturing conditions are effective to cause at least a portion of the target species to denature to a measurable extent. The method further involves detecting a denaturation signal of each target species in the presence of the at least one test compound; and comparing the denaturation signal of each target species in the presence of the at least one test compound with a denaturation signal of the same target species in the absence of the at least one test compound under the same isothermal denaturing conditions.
更多76. PRIMER SET FOR AMPLIFYING TARGET SEQUENCE(S) OF ANTIBIOTIC-RESISTANT BACTERIAL SPECIES, PROBE OR PROBE SET SPECIFICALLY HYBRIDIZING WITH TARGET SEQUENCE(S) OF ANTIBIOTIC-RESISTANT BACTERIAL SPECIES, METHOD OF DETECTING ANTIBIOTIC-RESISTANT BACTERIAL SPECIES USING THE PROBE OR PROBE SET, AND KIT FOR DETECTING ANTIBIOTIC-RESISTANT BACTERIAL SPECIES
申请号: US11863984
申请日: 2007-09-28
公开（公告）号: US20090163382A1
公开（公告）日: 2009-06-25
发明人: Ji-Young OH; Yeon-su LEE; Sang-hyun PAEK; Byung-chul KIM; Sook-young KIM; Kyung-hee PARK; Jung-nam LEE; Jong-suk CHUNG; Ah-gi KIM; Myo-yong LEE; Tae-jin AHN
Provided are a primer set for amplifying target sequence(s) of antibiotic-resistant bacterial species, a probe or probe set specifically hybridizing with target sequence(s) of antibiotic-resistant bacterial species, a microarray immobilized with the probe or probe set, a kit comprising the primer set and a method of detecting at least one antibiotic-resistant bacterial species using the probe or probe set.
更多77. LEPA / GUF1 GENE SEQUENCES AS A DIAGNOSTIC TARGET FOR THE IDENTIFICATION OF BACTERIAL SPECIES
申请号: PCT/EP2009057389
申请日: 2009-06-15
公开（公告）号: WO2010003765A2
公开（公告）日: 2010-01-14
发明人: BARRY THOMAS GERARD; MAHER MAJELLA; SMITH TERENCE JAMES; O'GRADY JUSTIN
The current invention relates to a diagnostic kit for a bacterial species and/or fungal and/or yeast species comprising at least one oligonucleotide probe capable of binding to at least a portion of the LepA and/or Gufl genes or its corresponding mRNA.
更多78. 10 종의 호흡기 질환을 야기시키는 박테리아의 표적 서열을 증폭시킬 수 있는 프라이머 세트, 10 종의 박테리아의 표적 서열에 특이적으로 혼성화하는 프로브 세트, 상기 프로브 세트가 고정화되어 있는 마이크로어레이 및 상기 프로브 세트를 이용하여 10 종의 박테리아의 존재를 검출하는 방법
申请号: KR1020060094673
申请日: 2006-09-28
公开（公告）号: KR1020080029102A
公开（公告）日: 2008-04-03
发明人: 오지영; 백상현; 박경희; 이정남; 정종석; 김아기
A primer set is provided to amplify a target sequence from bacteria causing 12 kinds of respiratory diseases. A probe set is provided to be specifically hybridized into the target sequence existing in a PCR product amplified by the primer set, thereby detecting at least one bacteria inducing the 12 kinds of the respiratory diseases. A detecting method is provided to detect the bacteria causing the respiratory diseases efficiently with high specificity. An oligonucleotide primer set for specifically amplifying at least one target sequence among Acinetobacter baumannii adeB gene, Bordetella pertussis Tcf gene, Chlamydophila pneumoniae Omp gene, Enterobacter aerogenes tsx gene, Enterobacter cloacae rpoS gene, Escherichia coli uspA gene, Klebsiella pneumoniae Wab gene, Legionella pneumophila Mip gene, Moraxella catarrhalis cop gene, Mycoplasma pneumoniae P1 gene, Pseudomonas aeruginosa ETA gene and Streptococcus pneumoniae lytA gene is selected from the group consisting of: an oligonucleotide set including at least one oligonucleotide selected from oligonucleotides consisting of more than 10 consecutive nucleotide fragments in SEQ ID : NOs. 1 and 2; SEQ ID : NOs. 3 and 4; SEQ ID : NOs. 5 and 6; SEQ ID : NOs. 7 and 8; SEQ ID : NOs. 9 and 10; SEQ ID : NOs. 11 and 12; SEQ ID : NOs. 13 and 14; SEQ ID : NOs. 15 and 16; SEQ ID : NOs. 17 and 18; SEQ ID : NOs. 19 and 20; SEQ ID : NOs. 21 and 22; and SEQ ID : NOs. 23 and 24. A method for detecting the presence of at least one bacteria among 12 bacteria inducing respiratory diseases consisting of Acinetobacter baumannii, Bordetella pertussis, Chlamydophila pneumoniae, Enterobacter aerogenes, Enterobacter cloacae, Escherichia coli, Klebsiella pneumoniae, Legionella pneumophila, Moraxella catarrhalis, Mycoplasma pneumoniae, Pseudomonas aeruginosa, and Streptococcus pneumoniae comprises the steps of: (a) contacting a sample with at least one oligonucleotide probe or oligonucleotide probe set to hybridize a target sequence in the sample with a probe sequence; and (b) detecting the hybridization degree between the probe and the target sequence in the sample. A kit for detecting the existence of the 12 respiratory diseases inducing bacteria comprises the primer set and an instruction manual.
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