US12060863B2
A chordwise segment connection structure for wind turbine blades includes: a blade body including a pressure side and a suction side; a leading edge shell and a trailing edge shell formed by the skin of the pressure side and the suction side along the chord length of the blade, the pressure side and the suction side being each provided with a spar cap; and a shear web provided in a cavity of the blade body and extending between the pressure side and the suction side to support the spar cap; wherein the spar caps on the pressure side and the suction side are bonded and fixed to a skin structure where the leading edge shell and the trailing edge shell are spliced, so that the leading edge shell and the trailing edge shell are spliced with the spar caps to form the profile of the wind turbine blade.
US12060862B2
A system includes a power generator which provides solvent passage from one of the liquids to the other liquid by means of an osmotic membrane provided between liquids taken to a first volume and to a second volume and having different densities and which provides increasing of the pressure of the liquid to which the solvent passage occurs and which provides generation of electricity from the formed pressure. Accordingly, the system includes a first regeneration unit and a second regeneration unit, a retaining chamber, a valve unit, a first density sensor, a second density sensor, and a control unit. The control unit is configured to determine the liquid having high density in accordance with the measurements taken and to determine the operation mode of the valve unit accordingly.
US12060860B2
The present invention relates to a seat plate for an injector, comprising: a planar main body having a first flat side and a second flat side; a passage, which extends through the planar main body from the first flat side to the second flat side; and an indentation region in the first flat side, which indentation region surrounds an opening of the passage. The seat plate is characterised in that a plurality of webs are formed in the first flat side through the indentation region, the ratio of length to width of each web lying in the range of 2.5-3.5:1, preferably in the range from 2.7-3.3:1, more preferably in the range from 2.9-3.1:1.
US12060858B2
An air filter element includes a filter arrangement, an elbow, and a filter element seal member. The filter arrangement includes a filter media pack having a dirty air inlet and a clean air outlet, wherein air flowing through the clean air outlet flows in a first axial direction and the clean air outlet defines a filter arrangement cross sectional area. The elbow has a first end constructed to extend from the filter arrangement clean air outlet, a second end wherein air flowing through the second end flows in a second axial direction, and an air flow enclosure extending from the elbow first end to the elbow second end. The air flow enclosure includes an air deflector constructed to direct air from the first axial direction to the second axial direction, wherein the second axial direction is different from the first axial direction, and an interior volume between the elbow first end and the elbow second end. The filter element seal member is located on the elbow second end, wherein the filter element seal member is constructed to seal to a clean air intake, the filter element seal member located on the elbow second end defining a seal member cross sectional area. The filter element can be characterized as having a ratio of the seal member cross sectional area to the filter arrangement cross sectional area of at least 0.5. The filter element can have a z-filter media pack for a pleated media pack. The air filter element can be arranged in an air cleaner.
US12060856B2
A canister is provided. The canister includes an inflow port, adsorbents, an atmosphere port, an outflow port, and an adjustment member. The adjustment member includes rod-like members. The adjustment member includes a positioning member configured to enable positioning of the adjustment member in a target chamber by being insertable in a second cylinder and by not being insertable in a first cylinder. The second cylinder has a cylindrical shape, the cross sectional area of which is larger than a cross sectional area of the first cylinder.
US12060851B2
A bypass turbofan with a nacelle delimiting a stream and including a cowl mobile in translation between an advanced position in which a window is open between the stream and the exterior, transmission systems, each of which includes at least one arm mobile in rotation between retracted and deployed positions across the stream, in which each transmission system is mobile in translation between advanced and retracted positions, for each arm, a flexible veil fastened to the arm and alternately occupying a folded or unfolded position, and, for each transmission system, an actuator configured to move the mobile cowl, the transmission system and each arm.
US12060845B1
A fuel and emissions control method for an internal combustion engine of a vehicle includes performing passive evaluation of individual cylinder fuel control (ICFC) multipliers by determining whether any of the ICFC multipliers exceed an ICFC multiplier threshold and, in response, determining first and second cylinder fuel-air (FA) imbalances during first and second passive evaluation stages, respectively, separated by a passive evaluation delay period, and based on a comparison between the first and second cylinder FA imbalances, either (i) passing, by the controller, the evaluation and maintaining, by the controller, the ICFC multipliers or (ii) failing, by the controller, the evaluation and (a) resetting, by the controller, the ICFC multipliers and (b) increasing, by the controller, the passive evaluation delay period and repeating the passive evaluation.
US12060837B2
A reduction gearbox is provided that includes a planetary gear arrangement disposed in a casing. The planetary gear arrangement includes a sun gear, planet gear assemblies, and a fore and aft ring gears. The sun gear is configured in communication with a cantilevered end of an input. Each planet gear assembly has a main gear meshed with the sun gear, a fore lateral gear and an aft lateral gear disposed on opposite sides of the main gear and rotating therewith. The main gear has a main gear pitch diameter and the fore and aft lateral gears having a lateral gear pitch diameter. The fore ring gear is meshed with the fore lateral gears. The aft ring gear is meshed with the aft lateral gears. The aft ring gear is independent of the fore ring gear. The planet gear assemblies are in communication with an output.
US12060833B2
In some examples, a gas turbine engine including a high-pressure (HP) spool assembly including a HP shaft, a HP compressor and HP turbine; a lower pressure (LP) spool assembly including a LP shaft and LP turbine; a motor-generator coupled to the LP shaft; and a controller. The controller is configured to control the motor-generator to operate in a motor mode to apply torque the LP shaft during a starting of the HP spool assembly, and control the motor-generator to operate in a generator mode for a least a period of time following the starting of the HP spool assembly.
US12060830B2
The present invention relates to an exhaust-gas treatment device for an aircraft engine, comprising an exhaust-gas channel, through which an exhaust gas of the aircraft engine flows, and a first cooling unit for cooling with ambient air, characterized by a second cooling unit, which is downstream of the first cooling unit with respect to an exhaust-gas flow in the exhaust-gas channel.
US12060825B1
A two-stage turbocharging energy-efficient self-adaptive control method based on multi-point intake and exhaust pressures in diesel engine turbocharging field, including: determining a target turbocharging pressure for plains upon diesel engine speed and load conditions; adjusting it to obtain optimal target turbocharging pressures for varying altitudes; using these and measured multi-point pressures in intake and exhaust pipelines as inputs, based on an energy utilization analysis model, to determine the two-stage turbocharging energy utilization efficiency suitable for different altitude environmental conditions; according to the optimal overall efficiency principle of the two-stage turbocharging system at variable altitudes, calculating opening degrees of the bypass valves that meets the target total pressure ratio by a valve control unit. Reasonable distribution of exhaust energy between the two-stage turbochargers is achieved. The invention can achieve an efficient utilization of exhaust energy, and self-adaptive control of a variable-altitude two-stage turbocharging system.
US12060824B1
An engine includes a combustion chamber, a fuel injector, a spark plug, and a piston. The combustion chamber receives air from an intake valve, which receives air from an external environment of the engine. The fuel injector includes a fuel channel, a fuel port, an air port, a needle valve, and a premixing tube. The fuel channel receives fuel from a fuel supply. The needle valve initially covers the fuel port, and actuates to fluidly connect the fuel port to the fuel channel such that the fuel port receives the fuel. The air port draws air into the fuel injector, and the premixing tube mixes the air and fuel to create a mixture. The mixture is fed into the combustion chamber along a central axis of the premixing tube such that the mixture intersects the electrode of the spark plug, which ignites the mixture to actuate the piston.
US12060823B2
A method for operating a conveying device for an aqueous urea solution in a motor vehicle, having a pump for conveying the aqueous urea solution, wherein the aqueous urea solution is conveyed from a tank along a pressure line to an injector, wherein the injector is arranged on an exhaust gas line and is designed to inject the aqueous urea solution into the exhaust gas line. The conveying speed of the pump is controlled depending on the opening operations and closing operations of the injector and/or the pressure conditions resulting therefrom in the conveying section between the pump and the injector.
US12060815B2
The invention relates to a variable valve train for switching an outlet valve of an internal combustion engine to an engine braking mode. The variable valve train has a camshaft with a first cam, which is designed as a normal operation cam, and a second cam, which is designed as an engine braking cam. A first rocking lever has a first stroke device which is designed for selectively making or breaking a first operative connection between the first cam and the outlet valve by means of the first rocking lever. A second rocking lever has a second stroke device which is designed for selectively making or breaking a second operative connection between the second cam and the outlet valve by means of the second rocking lever. A valve device selectively connects the first stroke device or the second stroke device to a fluid feed line.
US12060814B2
A shifting stopper latch assembly for a rocker arm can comprise a latch assembly housing, comprising a latch assembly oil feed, a piston bore, a stopper bore comprising a stopper opening, and a spring seat. A piston can be in the piston bore. A shifting stopper can be in the stopper bore and the shifting stopper can comprise a projection protruding out of the stopper opening. A return spring can be configured in the spring seat to bias the shifting stopper and the plunger away from the spring seat and towards the latch assembly oil feed. A valvetrain can comprise a rocker arm configured to actuate against a cam on a cam rail, and the rocker arm can comprise a latch surface configured to selectively engage and disengage the projection.
US12060808B2
A turbine rotor includes a rotor body and a balancing weight slot defined in an exterior circumference of the body. The balancing weight slot has a first axial width and a first radially outward facing surface at a first radial distance from a rotor axis. The rotor also includes a balancing weight entry port defined in a portion of the exterior circumference of the rotor body and aligned with the balancing weight slot. The balancing weight entry port has a second axial width greater than the first axial width and a second radially outward facing surface at a second radial distance from the axis of the rotor body that is smaller than the first radial distance. A method may include machining the entry port into the rotor with a tool. The method may be applied to a new rotor, or to remove cracks initiating from a previous entry port.
US12060800B2
An assembly for rotational equipment includes a rotor, at least one sensor, and a controller. The rotor includes a first plurality of teeth arranged on the rotor in a first circumferential array of teeth at a first axial position. The at least one sensor includes a first sensor positioned radially adjacent the first circumferential array of teeth at the first axial position. The at least one sensor is configured to generate an output signal waveform. The controller is in signal communication with the at least one sensor. The controller includes a processor and non-transitory memory in signal communication with the processor. The non-transitory memory stores instructions which, when executed by the processor, cause the processor to measure a dynamic whirl displacement of the rotor at the first axial position using the output signal waveform.
US12060798B2
This disclosure is directed to seal assemblies for a turbomachine. The seal assemblies include stationary and rotating components and at least one interface between the stationary and rotating components. In some examples, seal assembly includes an oleophilic coating disposed between the stationary and rotating components. The seal assembly may include a surface texture to enhance the oleophilicity of the surface coating disposed between the stationary and rotating components. In other examples, the seal assembly includes an oleophobic coating disposed between the stationary and rotating components. The seal assembly may include a surface texture to enhance the oleophobicity of the surface coating. During operation, the oleophilic seal assembly features retain lubricant between the stationary and rotating components and the oleophobic seal assembly features inhibit the escape of lubricant from the contact regions between the stationary and rotating components.
US12060783B2
A system may have a built hydraulic fracturing system with a plurality of devices connected together and in fluid communication with one or more wells. The system may also include at least one continuous pumping operations for one or more wells and a fracturing pumping plan provided on a software application. The fracturing plan may include instructions to perform at least one continuous pumping operations for the one or more wells. The instructions may include a sequence of valve operations to direct fluid flow through a selected path into the one or more wells.
US12060778B2
A perforating gun assembly may include a housing extending along a first axis, a movable structure provided within the housing, and a tool string component coupled to the housing and abutting the moveable structure. The movable structure may be movable between a first position along the first axis relative to the housing and a second position along the first axis relative to the housing.
US12060777B2
A rotating ball valve may be employed in a liner hanger setting tool. A rotating ball member maintains contact with a valve seat throughout the operation of the rotating ball valve, thereby preventing debris from settling on the valve seat and compromising the integrity of a seal through a fluid flow path defined through the setting tool. The rotating ball valve may be actuated by selectively applying fluid pressure to the flow path, or by mechanical manipulation. Once the fluid flow path is closed, a latch may be activated to maintain the rotating ball valve in the closed configuration and a pressure may be applied against the closed rotating ball member. A downhole movement be induced by the applied pressure to drive an expansion cone through an expandable liner hanger, to secure a liner in the wellbore.
US12060774B2
A sealing unit (115) for sealing an annular gap (109) formed between a seal wear ring (106) and a seal carrier (112) has a sealing ring holder (118) which is U-shaped in a receptacle region and which, together with the receptacle region, encloses a fixing region (209) of the sealing ring (121).
US12060773B2
A method for controlling a wellbore pressure. The method includes disposing a tubing within a casing of a wellbore to form a tubing casing annulus. The method includes installing a tubing-packer sealing assembly within the casing to seal a downhole portion of the wellbore from an uphole portion. The tubing is disposed in the uphole portion of the wellbore. The method includes filling the tubing casing annulus in with an annulus fluid. The method includes, after filling the tubing casing annulus with the annulus fluid, injecting a volume of inert gas into the tubing casing annulus causing an equal volume of the tubing casing annulus fluid to be flowed out of the wellbore. The method includes after injecting the volume of the inert gas, sealing the annulus fluid and the inert gas in the tubing casing annulus.
US12060765B1
A tubing is anchored in a boiler casing positioned in a borehole that extends into a magma reservoir. The tubing may include a notch that is secured to a tubing anchor receptacle of the boiler casing. The boiler casing may include a float shoe that helps to prevent or restrict the flow of magma from the magma reservoir into the boiler casing and tubing.
US12060757B2
A self-erecting launcher assembly includes a mobile unit, and a magazine positioned in a receptacle of the mobile unit. The magazine includes a plurality of drones. A rail unit is secured to the mobile unit and moves between a closed position and an elevated position. A platform may be secured to the rail unit and is movable in an upward direction and a downward direction along a length of the rail unit. The platform is movable when the rail unit is in its elevated position. The magazine or the plurality of drones may be positioned on the platform, such that the platform moves the magazine or the plurality of drones from the mobile unit to at least one wellhead. A manipulator arm is secured to the platform and selects a drone of the plurality of drones and delivers the selected drone into a lubricator positioned at the wellhead.
US12060752B2
A wrench for making up or breaking up a pipe joint is provided. The wrench comprises a tong assembly having an upper tong and a lower tong. The upper tong has a first upper tong half pivotably connected to a second upper tong half at their first ends. The lower tong has a first lower tong half pivotably connected to a second lower tong half at their first ends. A central bearing operatively couples the upper tong and the lower tong to allow the upper tong to rotate relative to the lower tong or vice versa. The tong assembly has a ram assembly for pushing or pulling the upper tong at a tangential location thereof and the ram assembly is retracted or extended to move the tong assembly between an open position, a closed position, and a rotated closed position where the upper tong is rotated relative to the lower tong.
US12060749B2
A composite glass pane having a first glass pane, a second glass pane, and an intermediate layer arranged between the first and second glass panes is described. The intermediate layer includes one cover layer based on a thermoplastic polymer, and a border seal. The first glass pane is arranged with an offset relative to the second glass pane, the intermediate layer is cut back along at least one edge of the composite glass pane by a border distance, and the border seal is arranged in a border gap delimited by the first glass pane, the second glass pane and the intermediate layer. The border seal contains a polymer fusible with a polymer of the cover layers.
US12060748B2
A fenestration unit including a first panel having a leading portion and a trailing portion, a second panel, and a frame including a first lateral member and a second lateral member. The first lateral member has a trolley space configured to slideably receive a trolley assembly. The trolley assembly includes a first trolley coupled to the leading portion of the first panel and a second trolley coupled to the trailing portion of the first panel. Each of the first and the second trolleys includes a guide pin slideably received in the leading and trailing tracks, respectively. The guide pins are configured to guide the first panel out of a coplanar relationship with the second panel when the first panel is slid to an opened position and guide the first panel into a coplanar relationship with the second panel when the first panel is slid to a closed position.
US12060747B2
A breakaway sash lug assembly for a hung window includes a sash mount seat attachable to a window sash and a lug body rigidly attached to the sash mount seat via a releasable coupling that is configured to release at least one side of the lug body from the sash mount seat upon application a relatively small external force on the lug body. The releasable coupling may inhibit damage from inadvertent contact between the lug body and other portions of the hung window, for example during tilting of the sash for cleaning. The releasable coupling may include a hinge and a latch and/or a snap attachment.
US12060743B2
A pet access control system according to various aspects of the present technology may comprise a door unit interoperable with a security panel holder. The door unit covers a passage through a structure, such as through the wall or door of a building. The door unit may include a connector that may be mounted on a legacy security panel holder or a dedicated mounting system for the door unit. The door unit may operate in conjunction with a pet identification system to automatically identify and grant access only to authorized pets. In various embodiments, the door unit may be controlled remotely, such as via a web browser on a remote computer or an app running on a smartphone.
US12060738B2
A guide assembly for a sliding shower door is provided with a bracket sized to be fastened to a shower door opening. The bracket has a first lengthwise retainer. A guide with a second lengthwise retainer is sized to be retained by the first lengthwise retainer of the bracket. The guide has at least one channel formed therein and is sized to receive a shower door pane within the channel for translation of the shower door pane relative to the guide.
US12060731B2
Locking mechanisms and methods of operating the locking mechanisms are disclosed. In one example, a locking mechanism may include a main hub assembly coupleable with a deadbolt, a clutch assembly coupled to the main hub assembly, and an actuator assembly coupled to the clutch assembly. The actuator assembly may include an actuator operable to bias a carriage along a first direction to bring the clutch assembly and the main hub assembly closer to one another along a second direction, wherein the second direction is perpendicular to the first direction. The locking mechanism may further include a thumbturn assembly coupled to the clutch assembly, the thumbturn assembly comprising a thumbturn positionable on an exterior side of a door.
US12060720B2
A binding wire supply system for a reinforcing bar binding machine for supplying binding wire to a reinforcing bar binding machine from the outside of the reinforcing bar binding machine that binds intersections of reinforcing bars with the binding wire, wherein the binding wire supply system includes a reel mounting unit on which a binding wire supply reel, which is arranged close to the reinforcing bar binding machine and supplies the binding wire to the reinforcing bar binding machine, is mounted; a binding wire adapter for introducing the binding wire supplied from the binding wire supply reel into a binding wire accommodating magazine of the reinforcing bar binding machine; and a binding wire insertion guide into which the binding wire is inserted from the reel mounting unit to guide the binding wire to the binding wire adapter.
US12060713B2
Some embodiments of the present disclosure relate to a roofing shingle comprising a substrate, wherein the substrate having a top surface and a bottom surface; and a material layer, wherein the material layer comprises graphene, wherein the material layer is disposed on or above the top surface of the substrate. Some embodiments of the present disclosure relate to a method comprising one or more of obtaining a substrate, wherein the substrate having a top surface and a bottom surface; obtaining a graphene composition, wherein the graphene composition comprises at least graphene; and applying the graphene composition to the top surface of the substrate or a surface above the top surface of the substrate to obtain a material layer comprising graphene.
US12060712B2
A structural post includes a base plate defining a plurality of through holes, and a post portion that includes at least a pair of internal walls and at least a pair of external walls. A connector block is configured to receive a locking screw and to engage with a bolt thread of a bolt. A lock plate has a plate thread that is configured to engage the screw thread of the locking screw, and the lock plate is configured to expand upon being drawn by the locking screw into tight engagement with the connector block. The expanded lock plate is configured to apply a force on one of the pair of internal walls and one of the pair of external walls.
US12060710B2
A precast concrete panel and method for forming the panel are disclosed. A method of forming the panel to be used as a floor, wall, or roof structure includes positioning one or more forming members within a casting bed having a plurality of upright surfaces defining a generally rectangular interior area, the one or more forming members comprising an insulating material extending along a length dimension of the one or more forming members to define a plurality of rectangular-shaped channels in a parallel and spaced-apart relationship, placing uncured concrete within the casting bed and allowing the concrete to cover the one or more forming members and substantially fill the channels, and allowing the concrete to cure.
US12060709B2
An example plasterboard includes a layer of hardened plaster material having a first surface and an opposed second surface and a layer of molded material having a surface that faces away from the layer of hardened plaster material. The surface of the layer of molded material has one or more raised features. The plasterboard also includes a liner between the first surface of the layer of hardened plaster material and the layer of molded material. Other examples include a method of forming such plasterboards and a method for installing such plasterboards.
US12060706B2
A kit and system for constructing structures including at least one core block, at least one fascia block that connects to the core block by mounting a shelf that extends from a face of the core block with a cut-out section of a face of the fascia block, such that the face of the core block and the face of the fascia block form a gap therein between.
US12060705B2
A body cleanser is provided. The casing has a switch valve installation position and a spray head installation position for installation of the switch valve and the spray head respectively. A plurality of waterway channels is provided inside the casing and arranged between the switch valve installation position and the spray head installation position. Starting ends of the waterway channels are provided with through holes communicated with water outlet holes of the switch valve. The starting ends of the two waterway channels with a maximum straight-line distance are on a first plane. The starting end of the remaining waterway channel(s) is connected with the corresponding water outlet hole through a respective communication member, so as being located between the starting ends of the two waterway channels with the maximum straight-line distance. The plane where the starting end of the remaining waterway channel is located is parallel to the first plane.
US12060704B2
A controller acquires image data captured by a camera which is located at a toilet to capture an image of a bowl of the toilet, determines whether an unacceptable matter being an object having a possibility of clogging the toilet is in the bowl by performing image recognition based on the image data, and sends, to a flush water controller, a flow prohibition signal of prohibiting flush water from flowing when it is determined that the unacceptable matter is in the bowl.
US12060698B2
An atmospheric water harvesting apparatus includes a post, a water capturing unit, a drive bearing, a motor, a water collecting member, and a power source. The water capturing unit comprises a cylindric wall. The cylindric wall is positioned concentrically with the post. The cylindric wall comprises an inner surface and an outer surface. The cylindric wall forms an air passageway having an air inlet and an air outlet. The inner surface of the cylindric wall is coated with a layer of triboelectric material. The drive bearing is rotatably mounted about the post. The drive bearing is provided with a plurality of radial bars. The water collecting member is located beneath the water capturing unit to collect water captured by the water capturing unit. The power source is electrically connected to the motor.
US12060695B2
A method for improving machine performance based on machine application identification can include training an application identification model. The method can also include receiving one or more images from a camera positioned on a machine performing an application, and feeding each of the one or more images into the trained application identification model. The trained application identification model provides a predicted application corresponding to the application being performed by the machine. The model also provides a probability that the predicted application corresponds to the application being performed by the machine. Application optimization parameters, based on the predicted application, are retrieved and distributed to the machine when the probability is greater than a selected confidence threshold.
US12060693B2
A shovel includes a lower traveling body, an upper turning body turnably mounted on the lower traveling body, an attachment attached to the upper turning body, a plurality of actuators including a first actuator and a second actuator and configured to drive the attachment and the upper turning body, and a processor configured to control an operation of the second actuator in accordance with an operation of the first actuator, wherein the processor is configured to, in response to determining that a predetermined condition on the operation of the second actuator is satisfied, control the operation of the first actuator such that the operation of the first actuator corresponds to the operation of the second actuator.
US12060684B2
A system for compaction measurement includes a first compaction measurement apparatus arrangeable on a compaction machine and configured to determine, on the basis of a measured acceleration of a measurement probe of the first compaction measurement apparatus as a result of a measurement vibration and/or an acceleration of a compaction element of the compaction machine, at least one first stationary compaction value that informs about a local compaction of the subsoil or the surfacing for at least a first position, and to output the same with associated positional information for the first position; a second compaction measurement apparatus being mobile and configured to identify, upon interaction or contact with the subsoil or the surface, the local compaction of the subsoil or the surfacing for at least the first position and to output, on the basis thereof, at least one first mobile compaction value with associated positional information for the first position; and a calculation unit configured to compare the first stationary compaction value and the first mobile compaction value so as to determine a correction value that depends on the deviation of the first stationary compaction value from the first mobile compaction value, or to determine and display a deviation.
US12060679B2
Unique, inexpensive, and. strong biocomposites are obtained from blending cellulose matrix materials pith lignocellulosic reinforcement materials with the aid of alkaline aqueous solvent and cold temperatures. These lignocellulosic composites (LCs) are produced without use of any thermoplastic resins, adhesives, catalysts, plasticizers or d chemical or physical procedures. The LCs include a matrix and a reinforcement material. The matrix is a cellulose material (e.g., cotton, hemp, flax, or wood) that is liquefied using an aqueous alkaline solvent solution under cold temperatures to more readily adhere and or incorporate/encapsulate the lignocellulosic reinforcements (wood chips, fibers, and other lignocellulosic sources).
US12060676B2
In an embodiment, metal-organic nanowires or nanofibers comprising polymer chains with around 100 or more repeat units are synthesized. The metal-organic nanowires or nanofibers are exposed to a reactive gas at a temperature in excess of around 100° C. and at a pressure in the range from around 0.001 to around 100 atmospheres.
US12060662B2
There are provided a towel cloth which has a bulky and fluffy texture, is less likely to undergo fluff dropping, and is excellent in water absorbency, and a manufacturing method thereof. For a towel cloth including a ground weave including a warp ground yarn and a weft ground yarn crossing each other therein, and a pile yarn locked to the ground weave, at least one of the warp ground yarn, the weft ground yarn, and the pile yarn is formed of a twisted union finished yarn, and the twisted union finished yarn includes a twisted union yarn including two or more rovings twisted in a primary twisting direction as a single yarn, one of the rovings having an even twist, and at least another of the rovings partially having a twist with irregular strand length and twisting angle, the twisted union yarn undergoing fiber opening and being puffy.
US12060660B2
The present invention provides a winding and twisting device for a ring spinning or ring twisting machine, comprising: a stator comprising a superconducting material, a stator cooling device, a rotor configured to generate a magnetic field, and a rotatable spindle, wherein the rotor and the stator are arranged co-axially to the spindle, and wherein the rotor has a ring/traveler system mounted thereon.
US12060642B2
A method of making an atomic layer nanoribbon that includes forming a double atomic layer ribbon having a first monolayer and a second monolayer on a surface of the first monolayer, wherein the first monolayer and the second monolayer each contains a transition metal dichalcogenide material, oxidizing at least a portion of the first monolayer to provide an oxidized portion, and removing the oxidized portion to provide an atomic layer nanoribbon of the transition metal dichalcogenide material. Also provided are double atomic layer ribbons, double atomic layer nanoribbons, and single atomic layer nanoribbons prepared according to the method.
US12060639B2
Provided herein are methods and related apparatus for purging processing chambers during an atomic layer deposition (ALD) process. The methods involve flowing purging gas from one or more accumulators to remove process gases from the processing chambers. Following the flowing of purging gas, additional reactants may be introduced into the processing chamber to continue an ALD cycle.
US12060638B2
Processing chambers and methods of use comprising a plurality of processing regions bounded around an outer peripheral edge by one or more vacuum channel. A first processing region has a first vacuum channel with a first outer diameter and a second processing region has a second vacuum channel with a second outer diameter, the first outer diameter being less than the second outer diameter.
US12060635B2
In a hard mask formed on a target film formed on a substrate, a first film having a stress in a first direction and a second film having a stress in a second direction opposite to the first direction are alternately stacked one or more times.
US12060634B2
A roller for transporting a flexible substrate is described. The roller includes a first coolant supply for cooling a first part of the roller and a second coolant supply for cooling a second part and a third part of the roller. The first part is provided between the second part and the third part. Additionally, a vacuum processing apparatus including a roller and a method of cooling a roller are described.
US12060623B2
A steel sheet including, in mass %, C: 0.05% or more and 0.30% or less, Si: 0.05% or more and 6.00% or less, Mn: 1.50% or more and 10.00% or less, and the balance: Fe and impurities, a steel sheet structure is composed of, in area ratio, 15% or more and 80% or less of ferrite and 20% or more and 85% or less in total of a hard structure composed of any one of bainite, martensite, or retained austenite, or any combination thereof, and to a steel sheet thickness t, an area ratio of a maximum coupled ferrite region in a region from a t/2 position at the steel sheet thickness center to a position at a depth of 3t/8 from a surface is 80% or more in area ratio to a total ferrite area, and a two-dimensional isoperimetric constant of the maximum coupled ferrite region is 0.35 or less.
US12060621B2
Related to is a system for preparing xylose liquid by continuously hydrolyzing hemicellulose, including a neutralizing unit, an acid-adjusting unit, a feeding unit, a liquefaction ejecting unit, a feed and discharge heat-exchanging unit and a discharge controlling unit. The neutralizing unit includes a raw material tank, a neutralizing concentrated sulfuric acid pump and a neutralizing pipeline mixer, the acid-adjusting unit includes an acid-adjusting concentrated sulfuric acid pump, an acid-adjusting pipeline mixer and an acid-adjusting tank, the feeding unit includes a feed tank, the liquefaction ejecting unit includes a liquefaction ejector and a liquefaction maintainer, the feed and discharge heat-exchanging unit includes a plate-type teed and discharge heat exchanger and a first discharge temperature sensor, and the discharge controlling unit includes a discharge valve and a reflux valve. The obtained xylose liquid exchanges heat with the hemicellulose liquid in the plate-type feed and discharge heat exchanger to decrease a temperature of the xylose liquid, whereas a temperature of the hemicellulose liquid is increased. Further disclosed is a method using the system. The simultaneous feed and discharge heat exchanges greatly reduce energy consumption, and feed and exchange are continuously run, thereby improving the production efficiency and simplifying manual operations.
US12060617B2
The present invention relates to a method for classifying a prostate cancer in a subject, the method comprising the steps of a) determining a gene expression level or gene expression pattern of the genes F3 and IGFBP3 in a sample from the subject and b) classifying the tumor by comparing the gene expression level determined in a) with a reference gene expression of the same genes in reference patients known to have a high risk tumor respectively. In addition the invention relates to a method for determining prognosis of a subject diagnosed with prostate cancer, a method for making a treatment decision for a subject diagnosed with prostate cancer and a solid support or a kit for classifying a tumor in a subject diagnosed with prostate cancer.
US12060615B2
The present invention provides methods for discovering agents that are effective in reversing epigenetic silencing by inhibiting the interaction of methyl-binding (MBD) proteins with methylated genomic DNA. Also provided are methods for reactivating silenced genes having CpG island hypermethylation along with methods for treatment and prevention of diseases, such as cancer and sickle cell anemia, by administering an agent that modulates methyl-binding domain (MBD) protein-mediated transcriptional repression, thereby increasing gene transcription to prevent or treat disease. Additionally, compounds identified by the present invention useful for treatment and prevention of diseases, such as cancer and sickle cell anemia, are provided.
US12060608B2
Disclosed herein are methods and systems for detection and discrimination of optical signals from a densely packed substrate. There have broad applications for biomolecule detection near or below the diffraction limit of optical systems, including in improving the efficiency and accuracy or polynucleotide sequencing applications.
US12060598B2
Mutant thioesterases having enhanced medium chain substrate activity, polynucleotides encoding and configured to express the mutant thioesterases in a transformed host cell, host cells transformed to contain the polynucleotides, and methods of using same.
US12060597B2
Several embodiments of the invention relate generally to a system and methods for the treatment of gaseous emissions comprising methane and one or more non-methane compounds that can influence the metabolism of methane-oxidizing microorganisms. In several embodiments, there is provided a system and methods for the treatment of methane emissions through the use of methanotrophic microorganisms to generate functionally consistent and harvestable products. Certain embodiments of the invention are particularly advantageous because they reduce environmentally-destructive methane emissions and produce harvestable end-products.
US12060590B2
Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
US12060588B2
The invention relates to methods of modifying DNA methylation by contacting a cell with a catalytically inactive site specific nuclease fused to an effector domain having methylation or demethylation activity and one or more guide sequences.
US12060585B2
Disclosed herein are polynucleotides encoding cell tags for use in immunotherapeutic applications, and systems comprising polynucleotide cell tags for regulating the activity of a cell. The compositions, methods and systems described herein provide tools for regulating activity of genetically engineered cells in a subject.
US12060584B2
Embodiments of the present disclosure relate to a D-amino acid oxidase mutant and application in preparing L-glufosinate thereof. The D-amino acid oxidase mutant has an amino acid substitution at at least one of position 62 and position 226 of an amino acid sequence of the D-amino acid oxidase mutant when compared to an amino acid sequence of a D-amino acid oxidase as set forth in SEQ ID NO. 1, the position 62 and position 226 being defined with reference to SEQ ID NO. 1, and the amino acid sequence of the D-amino acid oxidase mutant having at least 90% identity to SEQ ID NO. 1.
US12060581B2
The invention provides methods and compositions for producing a multi-layered cellular structure or blastocyst-like structure from a cell population of reprogrammed somatic cells.
US12060579B2
Provided herein are methods that enable the polarization of hPSC mesoderm such that closely related yet distinct cardiovascular populations can be generated efficiently without the need of post-facto enrichment.
US12060572B2
The present invention relates to methods for targeted insertion of at least one nucleic acid sequence/s of interest into a target genomic locus of a mammalian cell. More specifically, the methods of the invention are based on using nucleic acid cassettes comprising the nucleic acid sequence/s of interest and at least one recognition signal sequence (RSS), for insertion of the nucleic acid sequence of interest into the target genomic locus that is mediated by RAG-catalyzed recombination. The invention further provides cassettes, vectors and vehicles and cells comprising said cassettes, compositions and uses thereof in immunotherapy.
US12060562B2
An expression system is provided, including a first nucleic acid fragment containing a long intergenic region (LIR) derived from geminivirus, a small intergenic region (SIR) derived from geminivirus, and an expression cassette of a target protein linked between the LIR and the SIR and a second nucleic acid fragment containing an expression cassette of a Rep/RepA protein derived from geminivirus, in which the expression cassette of the target protein includes a promoter, a nucleic acid fragment encoding the target protein, and two or more linked terminators in this order.
US12060552B2
The present invention relates to a new apparatus and a new method for the purification and the recovery of extra-chromosomal nucleic acids sequence(s).
US12060550B1
A fermentation device includes a fermenter. The fermenter includes a tank, augers, and a motor. The tank is horizontally arranged. A first end of the tank is connected with a material feeding port. A second end of the tank is connected with a material discharging port. A height of the material discharging port is not less than a height of the tank. Liquid raw material and solid raw material are added into the tank from the material feeding port. The augers are arranged in the tank. Each of the augers includes a central shaft and a blade. An inner edge of each blade is connected with a corresponding central shaft. A gap is defined between an outer edge of each blade and inner walls of the tank. The motor is connected with the augers and drives the augers to rotate in a first direction or a second direction.
US12060543B2
Ambient moisture-activatable surface treatment powders containing persalt, positively charged phase transfer agent and alkaline pH buffering may be activatable without the addition of liquid. Some ambient moisture-activatable surface treatment powders are substantially free of bleach activators and/or chlorine. Methods of use of ambient moisture activatable powders include applying them to the surfaces to be treated.
US12060542B2
The present invention relates to compositions such as cleaning compositions comprising enzymes. The invention further relates to the use of the compositions comprising such enzymes in cleaning processes.
US12060541B2
The subject invention provides yeast-based products, as well as their use to improve industrial production and performance by, for example, efficiently cleaning contaminating and/or fouling substances such as FOG, biofilm, paraffin, and/or asphaltenes from industrial equipment.
US12060537B2
Lubricant compositions comprising (a) an oil of lubricating viscosity and (b) a phosphonate ester other than a zinc salt. The phosphonate ester may be the reaction product of (i) phosphonic acid or a monomeric ester thereof with (ii) a propanediol having hydroxy groups in both the 1 and 3 positions and one or more of the carbon atoms of the propyl units are substituted with one or more alkyl groups such that the total number of carbon atoms in the propanediol ranges from 4 to 12. The molar ratio of (i) to (ii) may be 0.9:1.1 to 1.1 to 0.9.
US12060533B2
A process for upgrading a hydrocarbon feed, such as crude oil or other heavy oils, may include hydrotreating a hydrocarbon feed in a hydrotreating unit to produce a hydrotreated effluent that includes asphaltenes, coke precursors, or both. The process further includes hydrocracking the hydrotreated effluent in a hydrocracking unit to produce a hydrocracked effluent, adsorbing at least a portion of the asphaltenes, coke precursors, or both, from the hydrotreated effluent, the hydrocracked effluent, or both, separating the hydrocracked effluent into at least an upgraded lesser-boiling effluent and a greater-boiling effluent in a hydrocracked effluent separation system, and steam cracking the upgraded lesser-boiling effluent to produce olefins, aromatic compounds, or combinations of these. The process may further include recycling the greater boiling effluent back to the hydrotreating unit and hydrocracking a middle distillate effluent from the hydrocracked effluent separation system. Systems for conducting the processes are also disclosed.
US12060528B2
Systems and methods for producing light olefins via catalytic cracking of naphtha are disclosed. A naphtha feed stream and lift gas stream are fed into a plurality of dense phase riser reactors, each of which is operated with a high solid volume fraction, a high superficial velocity, and minimum back mixing. The effluent stream from each dense phase riser reactor is further separated, in a secondary reactor, to form a gaseous product stream and a catalyst stream. The catalyst stream is stripped to remove the hydrocarbons adsorbed on the catalyst particles. The stripped catalyst is regenerated in a regenerator.
US12060524B2
Compositions containing a diverting material, and related methods and systems for diverting a fluid from a high permeability zone in an underground formation to a low permeability zone in the underground formation. The diverter material contains a polyurethane and a second polymer. The compositions, methods and systems may be used to achieve more homogeneous stimulation during a well stimulation treatment.
US12060499B2
A dynamic cross-linked polymer nanocomposite adhesive has been developed by the oxidation of a thiol functionalized semi-crystalline and/or amorphous oligomer and thiol functionalized Cellulose Nanocrystals (CNCs) to form a polydisulfide network. The resulting solid material has a melting point transition at ca. 75° C. which corresponds to the melting of the semi-crystalline and/or amorphous phase of the nanocomposite adhesive. At higher temperatures (ca. 150° C.), results in the dynamic behavior of the disulfide bond being induced, where the bonds break and reform. Two levels of adhesion are obtained, in some embodiment by (1) heating the adhesive material to 80° C. (melting the semi-crystalline and/or amorphous phase) resulting in a lower modulus/viscosity of the adhesive, thus allowing better surface wetting on a substrate and (2) heating the adhesive material to 150° C. (inducing dynamic behavior of disulfide bonds), further lowers the modulus/viscosity of the adhesive ensuring a much better surface wetting and stronger adhesive bond. The polymer adhesive has been demonstrated to bind to, relatively high surface energy substrates including metal and hydrophilic glass, and to low surface energy substrates such as hydrophobic glass.
US12060495B2
The present invention relates to a powder coating composition for preparing a dielectric coating. The powder coating composition includes: (a) an epoxy functional polymer; (b) a poly-carboxylic acid functional polyester polymer reactive with the epoxy functional polymer and which has an acid value of less than 100 mg KOH/g; and (c) a poly-carboxylic acid functional (meth)acrylate polymer reactive with the epoxy functional polymer. Further, if a colorant is present, the powder coating composition comprises 35 weight % or less of the colorant, based on the total solids weight of the coating composition.
US12060493B2
An ink set is an ink set including a treatment liquid having a pH of 4.5 or less or 9.5 or greater, and an ink containing a compound A which generates gas in an environment of a pH of 4.5 or less or 9.5 or greater, a resin, water, and a white pigment and having a pH of greater than 4.5 and less than 9.5, in which a ratio of a content mass of the white pigment to a content mass of the compound A in the ink is 1 or greater and 160 or less.
US12060485B2
The present invention relates to a non-coating thermoplastic resin composition, a method for manufacturing a molded article by using the same, and a molded article manufactured by the same. More specifically, the present invention is characterized by providing the thermoplastic resin composition which contains polycarbonate, polysiloxane-polycarbonate copolymer, polyester, master-batched carbon black, and additives in specific contents and the molded article, which has excellent chemical resistance, mechanical properties, light resistance, hydrolysis resistance, and low glossiness, manufactured by using the same.
US12060484B2
A biodegradable polymeric composition for food contact applications is disclosed. This polymeric composition includes at least (1) from about 5 weight percent to about 95 weight percent poly(hydroxyalkanoates); (2) from about 5 weight percent to about 95 weight percent of at least one biodegradable polymer selected from the group consisting of poly(butylene succinate), poly(butylene succinate-co-adipate), poly(butylene adipate-co-terephthalate, poly(caprolactone), poly(lactic acid), cellulose esters (such as cellulose acetate) thermoplastic starch, and mixtures thereof; and (3) from about 0.1 weight percent to about 5 weight percent of a nucleating agent.
US12060483B2
Provided are compositions including a core moiety and a plurality of polymeric units, in which at least one of these can include an ionizable moiety or an ionic moiety. The core moiety may be a multivalent core moiety, trivalent core moiety, tetravalent core moiety, pentavalent core moiety, or multivalent arylene moiety. Materials, electrochemical cells, and methods using such compositions are also described.
US12060476B2
The present invention discloses a rubber composition, a processing method for obtaining the rubber composition, a rubber hose using the rubber composition and a production method thereof. The rubber composition comprises, in parts by weight, 100 parts of a rubber matrix, 1.5-8 parts of a crosslinking agent, 50-200 parts of a reinforcing filler, 10-100 parts of a plasticizer, and also 0.2-8 parts of an auxiliary crosslinking agent, 2-15 parts of a metal oxide, 1-3 parts of a stabilizer and 1-5 parts of polyethylene glycol, wherein, with respect to 100 parts by weight of total amount of said rubber matrix, said rubber matrix comprises a branched polyethylene with a content represented as A, in which 0
US12060472B2
An optical member resin sheet has excellent characteristics as an optical member and exhibits excellent performance even if used for a light-emitting device or the like. The optical member resin sheet is characterized in that the difference between the thickness of an end of the sheet and the thickness of the center of the sheet in the width direction of the sheet is within 5.0% of the total film thickness of the sheet; in that the thickness of the center of the sheet is in the range of 10-1000 μm; in that the sheet area is 225 mm2 or more; and by containing at least one fluorescent substance or reflective material.
US12060471B2
The present invention relates to an insulation body based a hard, fine-cell and open-cell polyurethane/polyisocyanurate foam with a barrier film, and a method for producing same.
US12060470B2
The present invention provides a polyolefin resin foam sheet having an area density of 5 g/m2 or more and 400 g/m2 or less, and having a time (t) required for a weight decrease from 90% by mass to 10% by mass, of 9 minutes or more, as measured by thermogravimetric analysis carried out at a heating rate of 10° C./min and a measurement temperature of 23° C. to 550° C. According to the present invention, a polyolefin resin foam sheet can be provided that has a high fire retardancy while maintaining a lightweight property.
US12060468B2
Provided are a composite material capable of further enhancing property derived from carbon nanotubes adhered to carbon fibers, a prepreg, a carbon-fiber-reinforced molded article, and a method for manufacturing a composite material. There is provided a composite material including: carbon fibers; and a structure which includes a plurality of carbon nanotubes and has a network structure in which the carbon nanotubes are in direct contact with each other, and in which the carbon nanotubes adhered to surfaces of the carbon fibers directly adhere to the surfaces of the carbon fibers. The carbon nanotubes have a bent shape having a bent portion.
US12060465B2
A composition and a method are provided for graphene reinforced polyethylene terephthalate (PET). Graphene nanoplatelets (GNPs) comprising multi-layer graphene are used to reinforce PET, thereby improving the properties of PET for various new applications. Master-batches comprising polyethylene terephthalate with dispersed graphene nanoplatelets are obtained by way of compounding. The master-batches are used to form PET-GNP nanocomposites at weight fractions ranging between 0.5% and 15%. In some embodiments, PET and GNPs are melt compounded by way of twin-screw extrusion. In some embodiments, ultrasound is coupled with a twin-screw extruder so as to assist with melt compounding. In some embodiments, the PET-GNP nanocomposites are prepared by way of high-speed injection molding. The PET-GNP nanocomposites are compared by way of their mechanical, thermal, and rheological properties so as to contrast different compounding processes.
US12060459B2
The invention relates to a process for preparing polyorganosiloxanes by (i) condensation polymerization of at least one linear organosiloxane which has at least one hydroxy group or hydrolysable group bound to a silicon atom, (ii) ring-opening polymerization of at least one cyclosiloxane, or (iii) ring-opening polymerization and condensation polymerization of a mixture of at least one linear organosiloxane which has at least one hydroxy group or hydrolysable group bound to a silicon atom and at least one cyclosiloxane with a basic initiator and a hydroxy group-containing compound in the presence of a polar aprotic solvent, wherein the obtained polyorganosiloxanes are not miscible in the polar aprotic solvent at room temperature.
US12060458B2
A polymer obtainable by reacting a compound A) comprising at least one five-membered cyclic monothiocarbonate group and at least one polymerizable, ethylenically unsaturated group, a compound B) comprising at least one amino group, selected from primary or secondary amino groups, optionally a compound C) which is different from compound A) and comprises at least one five-membered cyclic monothiocarbonate group, and optionally a compound D) which is different from compound A) and comprises at least one functional group that reacts with a group —SH.
US12060453B2
Provided is a polyester carbonate resin having a constituent unit (I) represented by the following general formula (1), a constituent unit (II) represented by the following general formula (2), and a constituent unit (III) represented by the following general formula (3): wherein, in the above formula (1), R1 to R3 each independently represent a hydrogen atom, a methyl group or an ethyl group, and in the above formula (2), Q represents a divalent linking group.
US12060452B2
Disclosed are polyol compositions with a low viscosity that exhibit superior heat resistance, enhanced stability in the presence of water, improved strength, hardness, and molding characteristics relative to known polyurethane materials. Disclosed is a polyol composition comprising: (a) at least one monomeric polyol comprising three or more hydroxyl groups; (b) at least one higher polyol comprising three or more hydroxyl groups; and (c) at least one polyhydroxylated aromatic compound; wherein the at least one higher polyol comprises residues of either or both of the at least one monomeric polyol and the polyhydroxylated aromatic compound linked by one or more carbonate groups, oxygen ether groups, or a combination thereof. Disclosed are methods of preparing the disclosed compositions. Disclosed are articles prepared from the disclosed compositions that exhibit flexural strengths in excess of 10,000 psi and flexural moduli in excess of 400,000 psi, and exhibit outstanding green strength.
US12060440B2
Compounds defined by Formula 4 are used as cyclophilin inhibitors for the prevention or treatment of diseases or disorders, such as organ injury or organ failure.
US12060431B2
The present invention relates to a CD20 binding antibody which is capable of depleting B cells, and a BLyS binding antibody which is capable of antagonizing BLyS, as a combination for use in the treatment of an autoimmune disorder. The invention also relates to dosages, duration of treatment and time lapses between administration of the CD20 binding antibody which is capable of depleting B cells, and the BLyS binding antibody which is capable of antagonizing BLyS.
US12060428B2
The present invention provides antibodies and antigen-binding fragments (e.g., human antibodies) that bind specifically to human Interleukin-36 receptor (IL36R). Methods for treating or preventing diseases mediated by IL36R (e.g., skin or colon inflammatory conditions such as palmo-plantar pustular psoriasis, palmoplantar pustulosis, generalized pustular psoriasis, ulcerative colitis or IBD) using the antibodies and fragments are also provided along with methods of making the antibodies and fragments.
US12060425B2
High-affinity antibodies recognizing Programmed Death Ligand-1 (PD-1) and Lymphocyte Activation Gene 3 protein (LAG-3) are disclosed. Binding sites from humanized anti-PD-1 and anti-LAG-3 antibodies are incorporated into a Fabs-in-Tandem Immunoglobulin format without significant loss of binding affinity, and the resultant bispecific, multivalent binding proteins are able to bind to both PD-1 and LAG-3 simultaneously. Such bispecific FIT-Ig binding proteins are useful for treatment of cancer.
US12060421B2
The present invention provides antibodies, or antigen binding fragments thereof, that bind to human TIGIT (T cell immunoreceptor with Ig and ITIM domains), as well as uses of these antibodies or fragments in therapeutic applications, such as in the treatment of cancer or chronic viral infection. Such method of treatment include combination therapy with inhibitors of other immunomodulatory receptor interactions, such as the PD-1/PD-L1 interaction. The invention further provides polynucleotides encoding the heavy and/or light chain variable region of the antibodies, expression vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies, cells comprising the vectors, and methods of making the antibodies or fragments by expressing them from the cells.
US12060419B2
The invention provides improved compositions for adoptive cell therapies for cancers that express CD79A.
US12060415B2
Isolated or recombinant EphA5 or GRP78 targeting antibodies are provided. In some cases, antibodies of the embodiments can be used for the detection, diagnosis and/or therapeutic treatment of human diseases, such as cancer. A method of rapidly identifying antibodies or antibody fragments for the treatment of cancer using a combination of in vitro and in vivo methodologies is also provided.
US12060412B2
Transcriptomes of individual neurons provide rich information about cell types and dynamic states. However, it is difficult to capture rare dynamic processes, such as adult neurogenesis, because isolation from dense adult tissue is challenging, and markers for each phase are limited. Here, Applicants developed Nuc-seq, Div-Seq, and Dronc-Seq. Div-seq combines Nuc-Seq, a scalable single nucleus RNA-Seq method, with EdU-mediated labeling of proliferating cells. Nuc-Seq can sensitively identify closely related cell types within the adult hippocampus. Div-Seq can track transcriptional dynamics of newborn neurons in an adult neurogenic region in the hippocampus. Dronc-Seq uses a microfluidic device to co-encapsulate individual nuclei in reverse emulsion aqueous droplets in an oil medium together with one uniquely barcoded mRNA-capture bead. Finally, Applicants found rare adult newborn GABAergic neurons in the spinal cord, a non-canonical neurogenic region. Taken together, Nuc-Seq, Div-Seq and Dronc-Seq allow for unbiased analysis of any complex tissue.
US12060409B2
The present invention relates to short cyclic peptides, their use in the treatment, amelioration or prevention of a disease caused by antibodies targeting the thyrotropin-TSH receptor (TSHR) in the thyroid gland, in particular Graves' disease and orbitopathy, and to pharmaceutical compositions comprising the same.
US12060406B2
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US12060392B2
The present disclosure relates to the identification, cloning, and expression of a genetic locus within an Enterococcus genome that encodes a phage tail-like bacteriocin (PTLB), termed an enterocin. Also provided are non-natural enterocins, which have been engineered to have altered bactericidal specificity. Nucleic acid molecules encoding natural or non-natural enterocins, vector constructs containing such nucleic acids operably linked to a heterologous promoter, producer cells containing such vectors, the encoded enterocins, as well as methods of making and using such enterocins are described.
US12060391B2
Embodiments disclosed herein provide nucleic acid constructs and methods of use thereof that induce a live cell to give off sub-samples of the cell's cytosolic content. The tem “cell” as used herein may be any cell type. In certain example embodiments, the cells are mammalian cells. The sampling can be general or can be targeted to a particular class of molecules or to specific types of molecules. The constructs facilitate generation of a read-out for high-throughput screens by combining engineered export with simple bulk sample and sample processing. Live cell sampling enables time course measurements and expands, for example, the applicability of transcriptional profiles obtained by single cell gene expression analysis.
US12060368B2
The present invention relates to a novel selenophenochromene hydroxamic acids as angiogenesis inhibitors, as well as methods of their manufacturing and use in different pharmaceutical compositions for the treatment or prevention of various diseases and disorders by administration of such substances.
US12060366B2
Disclosed are degraders, pharmaceutical compositions containing them, and methods of making and using the degraders to treat diseases and disorders characterized by aberrant protein activity that can be targeted by cereblon.
US12060349B2
The invention relates to inhibitors of glucosylceramide synthase (GCS) of the Formula I: represented by the following structural formula or a pharmaceutically acceptable salt thereof, wherein the variables are as defined herein, useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, cystic disease and for the treatment of cancer.
US12060347B2
Disclosed are compounds of Formula (I) to (VIII): or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate or prodrug thereof, wherein R3 is a bicyclic heteroaryl group substituted with zero to 3 R3a; and R1, R2, R3a, R4, and n are defined herein. Also disclosed are methods of using such compounds as PAR4 inhibitors, and pharmaceutical compositions comprising such compounds. These compounds are useful in inhibiting or preventing platelet aggregation, and are useful for the treatment of a thromboembolic disorder or the primary prophylaxis of a thromboembolic disorder.
US12060346B2
The disclosure provides at least one entity chosen from compounds of formula (I), solid state forms of the same, compositions comprising the same, and methods of using the same, including use in treating focal segmental glomerulosclerosis (FSGS) and/or non-diabetic kidney disease (NDKD).
US12060338B2
The invention relates to 1,5-benzothiazepine and 1,2,5-benzothiadiazepine derivatives of formula (I). These compounds are bile acid modulators having apical sodium-dependent bile acid transporter (ASBT) and/or liver bile acid transport (LBAT) inhibitory activity. The invention also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the treatment of cardiovascular diseases, fatty acid metabolism and glucose utilization disorders, gastrointestinal diseases and liver diseases.
US12060335B1
A 2-(benzo[d]oxazol-2-yl)-N′-(3,5-dichlorobenzoyloxy)acetimidamide compound, its synthesis, and its use as an antimicrobial agent.
US12060334B2
The present invention provides phenazine derivatives, such as compounds of Formula (I). The compounds of the invention are expected to be antimicrobial agents and may act by a microbial warfare strategy (e.g., a reactive oxygen species (ROS)-based competition strategy). The present invention also provides compositions, kits, uses, and methods that involve the compounds of the invention, which may be useful in preventing or treating a microbial infection (e.g., a bacterial infection or mycobacterial infection) in a subject, inhibiting the growth and/or reproduction of a microorganism (e.g., a bacterium or mycobacterium), killing a microorganism (e.g., a bacterium or mycobacterium), inhibiting the formation and/or growth of a biofilm, reducing or clearing a biofilm, and/or disinfecting a surface.
US12060333B2
The present invention relates to compounds of formula (I), wherein R1-R5 and L are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds.
US12060326B2
The present invention relates to a laurolactam preparation method and synthesis apparatus, and epoxidation and a rearrangement reaction are performed in the conversion of cyclododecene into cyclododecanone so that the preparation method can synthesize laurolactam having a higher purity with a higher selectivity and in a higher yield than a conventional preparation method.
US12060325B2
Disclosed is a high yield, high selectivity and high conversion method to produce Dimethyl Carbonate (DMC) from carbon dioxide (CO2) and methanol (MeOH) using optimized concentration of ethylene oxide as water scavenger. The method provides an alternative and optimized solution towards the problem of formation of water in DMC synthesis by reporting optimal feed ratio and scavenger to MeOH feed ratio. The disclosure also discloses an optimal pressure condition that could have significant impact on economy of compression of the feed to the DMC reactor.
US12060323B2
The present invention relates to a 6-hydroxy-3-hexenyl alkoxymethyl ether compound of the following general formula (1): HOCH2CH2CH=CHCH2CH2OCH2OCH2R1 (1), R1 representing a hydrogen atom, an n-alkyl group having 1 to 9 carbon atoms, or a phenyl group; and also relates to a process for preparing a 3,13-octadecadien-1-ol compound of the following formula (6): CH3(CH2)3CH—CH(CH2)8CH═CHCH2CH2OH (6) from the 6-hydroxy-3-hexenyl alkoxymethyl ether compound (1).
US12060319B2
The present invention relates to a preparation process for a Cu-based catalyst and use of the Cu-based catalyst as the dehydrogenation catalyst in producing a hydroxyketone compound such as acetoin. Said Cu-based catalyst shows a high the acetoin selectivity as the dehydrogenation catalyst for producing acetoin.
US12060315B2
Methods are provided for the synthesis of a compound of formula (X). R2 is selected from —H, —C1-C4-alkyl, —C2-C4-alkenyl and C1-C4-aryl; R3 is selected from —C(O)H and —C(O)C1-C4-alkyl; and A is a pharmaceutically acceptable anion (e.g. a halide). Also provided are intermediate compounds formed during the synthesis.
US12060314B2
Vinylidene olefins may undergo hydroformylation in the presence of an unmodified cobalt catalyst to form compositions comprising a mixture of alcohol molecules having a specified amount of branching. In particular, the compositions may feature a mixture comprising reduced hydroformylated reaction products of a vinylidene olefin comprising alcohol molecules represented by at least one of Structures 3-5. The mixture has an average of about 1.2 to about 2.1 branches per alcohol molecule. Ra and Rb may be the same or different and comprise a branched or unbranched alkyl group having about 6 to about 14 carbon atoms, excluding branches. Variable m is an integer ranging from 0 to a number of carbon atoms in Rb. Rb is a branched or unbranched alkyl group having m+1 carbon atoms less than Rb.
US12060310B2
The present invention is directed to itaconic acid derivatives, compounds comprising the derivatives and methods of using the derivatives in the treatment of cancer, inflammation, and autoimmune diseases.
US12060303B2
A metering device (10) for withdrawing and dispensing a melt consisting of or containing an oxide fibre reinforced oxide ceramic composite material.
US12060300B2
A method is provided for calculating gaseous diffusion and oxidation evolution of a ceramic matrix composite (CMC) structure, which includes determining temperature and load distribution in a structural member; determining matrix crack distribution in the structure; establishing an equivalent diffusion coefficient model of a fiber bundle scale to predict a gas flow channel in a fiber bundle: averaging a total amount of gaseous diffusion in the channel to establish the equivalent diffusion coefficient model of the fiber bundle composite scale related to the matrix crack distribution; establishing a representative volume element (RVE) model; establishing an equivalent diffusion coefficient model of a RVE scale; calculating the distribution of the gas concentration and oxidation products in the structure; calculating a growth thickness of an oxide at cracks and pores in each element; and updating sealing conditions of the gas channel, and calculating a new equivalent diffusion coefficient field and the distribution of the oxidation products again.
US12060295B2
Methods for controlling a converter for converting glass tubes to glass articles include preparing condition sets including settings for a plurality of process parameters, operating the converter to produce glass articles, measuring attributes of the glass articles, operating the converter at each of the condition sets, associating each glass article with a condition set used to produce the glass article and the attributes measured, developing operational models from the attributes measured and the condition sets, determining run settings for each of the plurality of process parameters based on the operational models, and operating the converter with each of the process parameters set to the run settings determined from the operational models.
US12060288B2
A wastewater treatment device has: an ozone generator which supplies ozone; a mixer which mixes ozone supplied from the ozone generator with wastewater and supplies ozone mixed wastewater; an ozone oxidation unit which progresses ozone oxidation in the ozone mixed wastewater while passing the ozone mixed wastewater therethrough and discharges wastewater in which the ozone has been consumed; a biological treatment unit which performs biological treatment on the wastewater discharged from the ozone oxidation unit using microorganisms; and an adjusting device which adjusts the amount of ozone to be mixed with the wastewater by the mixer so that ozone in an amount that inhibits the microorganisms of the biological treatment unit does not remain in the wastewater discharged from the ozone oxidation unit.
US12060276B2
The present invention provides a method for producing a novel amorphous silicon sacrifice film and an amorphous silicon forming composition capable of filling trenches having a high aspect ratio to form an amorphous silicon sacrifice film that is excellent in affinity with a substrate. A method for producing an amorphous silicon sacrifice film, comprising (i) polymerizing a cyclic polysilane comprising 5 or more silicon or a composition comprising the cyclic polysilane by light irradiation and/or heating to form a polymer having a polysilane skeleton, (ii) applying an amorphous silicon forming composition comprising said polymer having a polysilane skeleton, polysilazane and a solvent above a substrate to form a coating film, and (iii) heating the coating film in a non-oxidizing atmosphere.
US12060266B2
A method for producing MEMS components comprises generating a carrier having a plurality of recesses. An adhesive structure is arranged on the carrier and in the recesses. A semiconductor wafer is generated, which has a plurality of MEMS structures arranged at the first main surface of the semiconductor wafer. The adhesive structure is attached to the first main surface of the semiconductor wafer, with the recesses being arranged above the MEMS structures and the adhesive structure not contacting the MEMS structures. The semiconductor wafer is singulated into a plurality of MEMS components by applying a mechanical dicing process.
US12060263B2
A provided protective cover member is a protective cover member configured to be placed on a face of an object, the face having an opening. The protective cover member includes a laminate, and the laminate includes: a protective membrane having a shape configured to cover the opening when the member is placed on the face; and an adhesive agent layer. The adhesive agent layer includes a thermosetting adhesive layer including a thermosetting resin composition. The thermosetting resin composition has a storage modulus of 1×105 Pa or more at 130 to 170° C. The above protective cover member is suitable for reducing deformation thereof and/or peeling thereof from a placement face in a high-temperature treatment such as reflow soldering.
US12060257B1
A post-mix beverage dispensing tap valve to dispense a beverage into a vessel. A connection and mounting assembly is configured for mounting the post-mix beverage dispensing valve a wall and connecting with a source of a beverage product and a source of water. A drafting head is formed as an elongate cylindrical body with an internal bore. A piston shaft is operable by a tap actuator to selectively block and permit a flow of the beverage syrup and the water through the internal bores. The piston shaft carries a seal, a flow guide, and a spring. The seal abuts and seal with the facet to prevent flow through the internal bores. A slight gap between the flow guide and the inner surface of the bore obtains a desired mixture rate between the beverage syrup and the water source by regulating the area of flow around the flow guide.
US12060254B2
A system and method for independently routing vehicles and delivering containers and closures to unit operation stations are disclosed. The containers and closures can, in some cases, be transported on the same vehicle. In other cases, the containers and closures can be transported on different vehicles.
US12060247B2
Methods and systems for elevator car level detection are provided. Aspects includes collecting, by at least one sensor, horizontal distance data and vertical distance data associated with a component of an elevator car in relation to a floor landing in a hoistway of a building, wherein the at least on sensor is affixed to the component of the elevator car and analyzing the horizontal distance data and the vertical distance data to determine one or more offset values associated with the elevator car and the floor landing.
US12060240B2
Provided are a roller assembly, a battery cell manufacturing device, and an adjustment method of a roller, which relates to the field of battery manufacturing technology. The roller assembly includes a holder, a roller, and a first adjusting member. The roller is rotatably mounted on the holder. The first adjusting member is rotatably mounted on the holder, and one end of the roller is rotatably connected to the first adjusting member. A rotation axis of the roller does not coincide with a rotation axis of the first adjusting member. One end of the roller is rotatably mounted on the holder through the first adjusting member. The rotation axis of the first adjusting member does not coincide with the rotation axis of the roller, and therefore, rotation of the first adjusting member is capable of driving a corresponding end of the roller to rotate, thereby adjusting an extension direction of the roller.
US12060233B2
Provided is a stick pick-up device which has a simple structure, is easy to control, and is capable of reliably picking up sticks one by one. The stick pick-up device includes a stick stock portion, a reverse inclined wall, and a push-up portion. The stick stock portion includes a stick receiving portion that is inclined down toward a downstream side and can store a plurality of sticks. The reverse inclined wall is provided on the downstream side of the stick receiving portion, and has a reverse inclined surface inclined in a direction covering over a stick receiving portion side. The push-up portion is provided on a reverse inclined surface side, has a stick push-up surface inclined down toward the downstream side, pushes up the sticks on the stick push-up surface one by one along the reverse inclined surface, and causes the sticks to move downstream over the reverse inclined wall.
US12060229B2
An extendable and retractable conveyor includes a hopper for receiving agricultural product, and a housing having an inlet and an outlet that are separated by a fixed distance, the inlet being adjacent to the hopper for receiving the agricultural product from the hopper. The extendable and retractable conveyor also include a belt conveyor disposed within the housing for conveying the agricultural product from the inlet to the outlet, the conveyor defining a direction of conveyance; a hood connected to the outlet for deflecting the agricultural product relative to the direction of conveyance; and a movable spout that is slidably connected to a tube and disposed beneath the hood to receive the agricultural product from the hood, the movable spout being slidable in a direction parallel to the direction of conveyance to thereby extend or retract the conveyor.
US12060223B2
An automated cryogenic storage system includes a freezer and an automation system to provide automated transfer of samples to and from the freezer. The freezer includes a bearing and a drive shaft though the freezer, the drive shaft being coupled to a rack carrier inside the freezer and adapted to be coupled to a motor. The automation module includes a rack puller that is automatically positioned above an access port of the freezer. The rack puller engages with a sample rack within the freezer, and elevates the rack into an insulating sleeve external to the freezer. From the insulating sleeve, samples can be added to and removed from the sample rack before it is returned to the freezer.
US12060221B2
A method for compensating the bathymetric pressure inside a subsea tank containing a liquid working fluid by using a bathymetric compensation fluid is provided. The liquid working fluid and the bathymetric compensation fluid are separated from each other by a separation layer of a separation fluid.
US12060213B2
A cartridge for a multi-component material, includes a hollow cylindrical inner body which defines an inner space for receiving a first component, a hollow cylindrical outer body which receives the inner body such that an intermediate space for receiving a second component is formed between an outer wall of the inner body and an inner wall of the outer body, an outlet emanating from the inner body and in a first passage which connects an outlet opening of the outlet to the interior of the inner body is formed, and a second passage connecting the outlet opening of the outlet to the intermediate space present between the outer body and the inner body. An end portion of the inner space that faces the outlet lies at least substantially in the same plane as an end portion of the intermediate space that faces the outlet.
US12060202B2
A container includes a base panel. An opposed pair of end panels extends from the base panel at opposite ends of the base panel. A front panel extends from the base panel and extends from a first one of the end panels to a second one of the end panels. A back panel extends from the base panel and extends from the first one of the end panels to the second one of the end panels. The end panels taper so top edges of the front and back panels are either longer or shorter than bottom edges of the front and back panels. Each end panel includes a plurality of overlapping end flaps adhered to one another. The end flaps of each of the end panels are connected to a respective one of the base panel and each of the front and back panel at respective fold lines.
US12060201B2
Blanks for forming clamshell containers and the resulting clamshell containers are described. The clamshell containers include a tray and a lid that are hingedly connected together. The tray is liquid tight, and typically includes gussets on each corner to prevent leakage. The lid and tray can be locked via at least one locking mechanism, optionally two different locking mechanisms. A first locking mechanism involves a front panel on the tray, with an extension portion that terminates in a hook or tab. The extension portion can fold over the front panel of the lid, and the hook or tabs slide into a slit(s) on the top of the lid. An optional second locking mechanism involves lid detents and tray detents. In some embodiments, in the locked position, the lid detents are underneath the tray detents and the tray detents retain the lid detents in place until a force is applied.
US12060199B2
A cap assembly for a refill capsule and associated refill system is disclosed. The cap assembly (200) comprises an inner wall (202) defining a conduit (203) through the cap assembly (200) and an outer wall (204) surrounding the inner wall to form a circumferential void between the inner and outer walls (202, 204). A connecting wall joins the inner and outer walls (202, 204). The cap assembly (200) further comprises a closure member (208) which is sealed to the inner wall (202) with a peripheral frangible connection (210). The frangible connection (210) is disposed between radially offset portions of the inner wall (202).
US12060196B1
A container system includes (I) a container including a top portion, a bottom portion, and intermediate portion to form an interior of the container; and (II) a tubular member including a longitudinal tubular portion extending from the top portion toward the bottom portion, and has a cross sectional flow area taken perpendicular to a flow direction, and an expanded tubular portion extending toward the top portion with a flow direction away from the bottom portion and toward the top portion. The expanded tubular portion includes a cross sectional flow area taken perpendicular to a flow direction that is unequal to a cross sectional flow area of the longitudinal tubular portion taken perpendicular to another flow direction. In addition, other aspects are described in the claims, drawings, and text forming a part of the present disclosure.
US12060192B2
Various embodiments of the present disclosure provide systems including stretch-hood machines configured to vertically and horizontally apply tubular stretch film to loads of goods and to methods for wrapping loads of goods with multiple segments of tubular stretch film.
US12060182B2
Plural articles are arranged in a reusable crate. A cardboard blank is selected in accordance with the volume of the arranged articles. The blank has a first and a second longitudinal score line defining a main portion and a first, a second, a third and a fourth lateral portion, the blank also having a first, a second, a third and a fourth incision that subdivide auxiliary portions into first parts and second parts. The blank and the reusable crate are reciprocally positioned, the bottom of the reusable crate then opened to release the articles onto the blank. The first, second, third and fourth lateral portions are folded towards the articles, with the respective first parts and second parts of the auxiliary portions folding one on another to form respective flaps abutting the group of articles.
US12060167B2
An unmanned aerial vehicle launch tube that has a tube, a sabot disposed in an interior of said tube, said sabot having a first clasp tab, and a clasp detachably coupled to said first clasp tab and contacting an inner circumferential wall of said tube so that said clasp is rotationally constrained by the inner circumferential wall and said first clasp tab.
US12060159B2
A system and method for reducing data noise for vehicle monitoring sensors using parameter-based correction. The system includes a sensor operable to make a sensor reading and generate a sensor signal, and a data server operable to acquire a condition indicator model correlating operational parameters with condition indicators, and to acquire a current condition indicator according to the sensor signal, the data server further operable to generate an adjusted condition indicator by adjusting the current condition indicator according to the condition indicator model, and to determine whether an alert condition is indicated, according to at least the adjusted condition indicator, by a condition indicator set that includes the adjusted condition indicator, and to provide an alert in response to determining that the alert condition is indicated.
US12060152B1
The present invention provides a system and method for monitoring conditions within an electrical distribution system. According to a first preferred embodiment, the present invention provides a sensor module delivery system which uses UAVs to deploy sensor modules within the electrical distribution system. According to a first preferred embodiment, the system includes a drone mounting system and a gripper mechanism for attaching to a sensor module. The system also includes an extended carbon fiber shaft which vertically extends down from the drone mounting system and which supports a controller module, a transceiver, a battery module, a camera and the gripper mechanism. According to a further preferred embodiment, the gripper mechanism includes two or more gripping arms which are movable by the controller module between a first open position and a second closed position.
US12060151B2
A system for performing work on electrical power lines and/or splices on electrical power lines comprises an unmanned aerial vehicle (UAV), a power line tool adapted to perch on an electrical power line and/or a splice on an electrical power line, a support frame selectively releasably attached to the UAV, and a plurality of flexible dielectric support lines attaching the power line tool to the support frame. Each of the support lines are attached to a corresponding attachment point on the support frame and a corresponding attachment point on the power line tool.
US12060149B2
A pitch angle blocking device for blocking the pitch angle of a multi-blade rotor that has neighboring first and second rotor blades in circumferential direction that extend from a rotor hub of a rotary-wing aircraft In non-operational mode of the rotary-wing aircraft. The present embodiments further relate to a multi-blade rotor of a rotary-wing aircraft that is adapted to receiving such a pitch angle blocking device, and to a rotary-wing aircraft with such a multi-blade rotor. The pitch angle blocking device comprises first and second attachment means that are configured to be non-rotatably and releasably attached to the first and second rotor blades spaced apart from the rotor hub, and a connecting device that non-rotatably connects the first attachment means with the second attachment means.
US12060147B2
An aircraft system for an aircraft, the aircraft system including a controller configured, during a take-off procedure, to receive a first signal indicative of a climb rate of the aircraft and, when the controller determines, on the basis of the first signal, that the climb rate of the aircraft is positive, cause a retraction alert to be issued to a flight crew of the aircraft, the retraction alert indicative that a landing gear of the aircraft is retractable.
US12060143B2
A method of controlling an electric marine propulsion system to propel a marine vessel includes receiving a user-set time, determining a time remaining based on the user-set time, and identifying a battery charge level of a power storage system on the marine vessel. A required battery power is then determined based on the time remaining and the battery charge level, and then an output limit is determined based on the required battery power to enable propelling the marine vessel for the user-set time without recharging the power storage system. The propulsion system is automatically controlled so as not to exceed the output limit.
US12060141B2
A drive device for a vessel includes an electric motor, driving a rotatable drive shaft; an elongate drive device housing, encapsulating the electric motor and the drive shaft; and a propeller, detachably mounted to the rotatable drive shaft. The drive device housing has an upper connection device. The upper connection device is symmetrical about a transverse axis, enabling the drive device housing to be mounted to a structure onboard the vessel in either of two longitudinal directions. The drive device and the hull of the vessel are separated from each other by using an isolation plate with a central isolation sleeve. The electric motor drives the drive shaft via an interconnected gear device encapsulated in the drive device housing or integrated as a part of the drive device housing and are arranged pivotably with respect to the tilt device housing.
US12060136B2
Floatable, torus-segment-like pontoon for a torus-like floating body constructed from a plurality of such pontoons, with a torus eye containing the torus axis of rotation. The pontoon comprises connecting means on substantially flat side surfaces, which are designed in such a way that adjacent pontoons can be joined in a positive-fitting manner in the axial direction; Receiving areas on the radially inner pontoon surfaces for receiving a component in the torus eye; Retaining means arranged on the radially outer pontoon surfaces for holding adjacent pontoons together in the torus circumferential direction and in the radial direction; and connecting means configured on one of the side surfaces as at least one groove extending in the radial direction and on the other side surface as at least one opposite, substantially complementary tongue opposite to the groove. Said pontoon made of plastic and produced by rotational melting, extrusion blow moulding or RIM process.
US12060132B2
A foldable scooter includes a frame and a steering column provided with a front wheel and pivotably mounted on the frame, which has a first portion supporting a rear wheel and a footboard, and a second portion supporting the steering column. The first portion and the second portion are connected by a swivel joint along a folding axis, allowing movement between:—an unfolded configuration in which the steering column projects upwards with respect to the footboard by extending in a median plane; and—a folded configuration in which the steering column is on a first side face with respect to the median plane and extends away from the median plane, at least partially underneath the footboard, along a first side edge of the footboard and opposite a first side surface of the rear wheel.
US12060118B2
Control systems and methods for an electric power steering (EPS) system of a vehicle include obtaining, by a controller of the vehicle and from a set of sensors, a set of parameters of an electric motor of the EPS system, the EPS system further comprising a steering column and a steering wheel, and controlling, by the controller, the EPS system by based on the set of measured parameters of the electric motor, performing vector type recursive least squares estimation (RLSE) of a plurality of lumped EPS parameters including applying a variable forgetting factor, generating steering angle torque commands based on the estimated plurality of lumped EPS parameters, and controlling the electric motor of the EPS based on the generated steering angle torque commands for more accurate control of a trajectory of the vehicle.
US12060115B2
On the opposite side to an output of a rotation shaft of an electric motor, a ventilation hole communicating between an electronic control unit (ECU) housing space and an electric motor housing space is formed to an end surface wall of a motor housing separating the respective housing spaces. The ventilation hole has a waterproof ventilation part that suppresses water passing but permits the passage of air and water vapor. This structure eliminated the influence of flying rocks and muddy water from the external environment, and suppresses for a long period of time the internal pressure fluctuation of the ECU housing space and the penetration of water into the housing space. Therefore, the internal pressure fluctuation of the housing space for the ECU and the penetration of water into the housing space for the ECU can be suppressed over a long period of time.
US12060113B2
An aerodynamics control system for a vehicle may include an underbody shield disposed at an underside of the vehicle, a strake assembly, and an actuator. The strake assembly may include one or more deployable strakes operably coupled to the underbody shield and having a deployed state in which the one or more deployable strakes extend away from the underbody shield to increase drag and reduce lift of the vehicle. The strake assembly may also have a retracted state in which the one or more deployable strakes do not extend away from the underbody shield. The actuator may be operable by a driver of the vehicle while driving to transition the strake assembly from the retracted state to the deployed state.
US12060112B2
A mounting system for connecting an upper body structure of a motor vehicle to a vehicle platform of the motor vehicle includes a hollow pillar element arranged lengthwise along a vertical vehicle axis; a fastening bracket laterally embracing a lower end portion of the hollow pillar element and including fastening interfaces for affixing the fastening bracket to the hollow pillar element at the lower end; a hollow clip-on connector arranged laterally along a longitudinal vehicle axis, the hollow clip-on connector defining a mounting platform including a horizontal resting surface for the hollow pillar element to be arranged thereupon at its lower end portion together with the fastening bracket and a vertical mating surface for abutting a corresponding mating surface of the fastening bracket; and a hollow side sill element arranged lengthwise along the longitudinal vehicle axis.
US12060104B2
A vehicle collision avoidance assist apparatus executes a collision avoidance steering maneuvering assist process of applying a steering force to an own vehicle to assist a collision avoidance steering maneuvering carried out by a driver when there is a probability that the own vehicle collides with an object ahead of the own vehicle, and the driver carries out the collision avoidance steering maneuvering to steer the own vehicle to avoid a collision of the own vehicle with the object. The apparatus notifies the driver of a necessity of carrying out the collision avoidance steering maneuvering when determining that there is the possibility that the own vehicle collides with the object ahead of the own vehicle.
US12060099B1
This disclosure describes, in part, a mobile apparatus for identifying items within a facility using an omnidirectional imaging system. For instance, the mobile apparatus may include a main frame, a chassis attached to the main frame, a basket that attaches to the chassis in order to prevent the basket from contacting the main frame, and an omnidirectional imaging system providing image data in and around the mobile apparatus. A user may place item(s) within a receptacle of the basket. The mobile apparatus may further include a handlebar module attached to the main frame, the handlebar module including the omnidirectional imaging system and a computing system for identifying items and events in and around the cart.
US12060080B2
Aspects of the disclosure relate to generating a puddle occupancy grid including a plurality of cells. For instance, a first probability value for a puddle being located at a first location generated using sensor data from a first sensor may be received. A second probability value for a puddle being located at a second location generating using sensor data from a second sensor different from the first sensor may be received. A first cell may be identified from the plurality of cells using the first location. The first cell may also be identified using the second location. A value for the cell may be generated using the first probability value and the second probability value.
US12060079B2
Systems, methods, and other embodiments described herein relate to resolving one or more deficiencies in autonomous driving requirements for a road segment. In one embodiment, a method includes receiving sensor data for a portion of the road segment from at least one sensor of a vehicle, and determining autonomous driving requirements for the portion of the road segment. The method includes identifying the one or more deficiencies in the autonomous driving requirements for the portion of the road segment based on the received sensor data and the determined autonomous driving requirements for the portion of the road segment. The method includes determining an alteration to the portion of the road segment to overcome the one or more deficiencies in the autonomous driving requirements for the portion of the road segment.
US12060072B2
An exemplary embodiment of the present disclosure relates to an apparatus providing drive guide information of a construction equipment includes: an information acquisition unit acquiring information generated according to a motion of the construction equipment; a storage unit storing an item defined for calculating a score for worker driving of the construction equipment and an equation for calculating the score for the item, and storing a guide phrase for each item and information on equipment setting change for each item; a control unit calculating the score for each item according to the information provided, and selecting an item which needs to be improved based on the calculated score for each item; and a display unit displaying a guide phrase matching an item selected according to an instruction of the control unit and information on equipment setting change matching the selected item at a predetermined time.
US12060062B2
A method is disclosed for analyzing historical accident information to adjust driving actions of an autonomous vehicle over a travel route in order to avoid accidents which have occurred over the travel route. Historical accident information for the travel route can be analyzed to, for example, determine accident types which occurred over the travel route and determine causes and/or probable causes of the accident types. In response to determining accident types and causes/probable causes of the accident types over the travel route, adjustments can be made to the driving actions planned for the autonomous vehicle over the travel route. In addition, in an embodiment, historical accident information can be used to analyze available travel routes and select a route which presents less risk of accident than others.
US12060056B2
In some embodiments, a rapid-response active suspension system controls suspension force and position for improving vehicle safety and drivability. The system may interface with various sensors that detect safety critical vehicle states and adjust the suspension of each wheel to improve safety. Pre-crash and collision sensors may notify the active suspension controller of a collision and the stance may be adjusted to improve occupant safety during an impact while maintaining active control of the wheels. Wheel forces may also be controlled to improve the effectiveness of vehicle safety systems such as ABS and ESP in order to improve traction. Also, bi-directional information may be communicated between the active suspension system and other vehicle safety systems such that each system may respond to information provided to the other.
US12060055B2
A vehicle is provided that includes a steering wheel, a steering wheel sensor sensing rotational movement of the steering wheel, an accelerator pedal actuatable to accelerate the vehicle, a brake pedal actuatable to decelerate the vehicle, and a sensor sensing a signal indicative of an acceleration or deceleration of the vehicle. The vehicle also includes at least one proximity switch located on the steering wheel, and a controller configured to process the rotational movement of the steering wheel and the sensed signal and control an interaction mode of the at least one input switch, wherein the controller changes the interaction mode of the at least one input switch based on the sensed steering wheel movement and the sensed signal.
US12060053B1
A military vehicle includes a frame, axle assemblies coupled with the frame that are configured to be driven to transport the military vehicle, an internal combustion engine configured to drive the axle assemblies, an electric motor configured to drive the axle assemblies, and processing circuitry. The processing circuitry is configured to operate the military vehicle according to different modes by generating control signals for the internal combustion engine and the electric motor and providing the control signals to the internal combustion engine and the electric motor. The modes include an economy mode, a summon mode, an environmentally reactive control mode, a weaponry status control mode, a boost mode, an escape mode, an optimized idle control mode, a transmission control mode, a supplemental electric vehicle mode, and a convoy mode.
US12060028B2
This invention relates to fabric for airbag comprising a textile substrate; and a coating layer on at least one side of the textile substrate, wherein coating layer comprises polyurethane resin, a crosslinking agent, and a hydrophilic thickener, and the crosslinking agent is a compound having a blocked active group, and a method for preparing fabric for airbag, comprising steps of: preparing a textile substrate; and forming a coating layer on at least one side of the textile substrate, wherein the step of forming a coating layer comprise steps of: adding a crosslinking agent and a hydrophilic thickener to an aqueous polyurethane dispersion to prepare a coating solution; applying the coating solution on at least one side of the textile substrate; drying the textile substrate on which the coating solution is applied; and heat treating the dried textile substrate.
US12060026B2
A hanging lug for a safety airbag includes a first sewing piece, a second sewing piece, and a connecting piece. The first sewing piece and the second sewing piece are respectively provided at two ends of the connecting piece. The connecting piece is used for passing through a slit of a metal member. The connecting piece is folded in half after passing through the metal member. The first sewing piece and the second sewing piece are arranged in a staggered manner. Also provided is a safety airbag. The connecting piece is folded in half after passing through the metal member, and the first sewing piece and the second sewing piece are arranged in a staggered manner, thereby increasing the total sewing line length of the hanging lug, preventing an OPW from being damaged, reducing the number of sewn layers, and facilitating sewing operation.
US12060023B2
The present invention is an airbag device mounted on a steering wheel of a vehicle having a rim with a shape in which the distance from the center of rotation to the distance to the upper edges is shorter than to left and right edges, that includes a gas generator that generates an expansion gas and an airbag that expands and deploys toward the occupant due to the expansion gas. Furthermore, at the stage before the occupant comes into contact with the expanded and deployed airbag, the thickness (width) D1 of the upper end part of the airbag in the direction parallel to the rotation axis of the steering wheel when the airbag is viewed from the side is configured to be larger than the thickness (width) D2 of the lower end part.
US12060019B2
A vehicle front structure including a left and right pair of front side members, a bumper reinforcement and a power unit. The bumper reinforcement includes a first breakage initiation point at a position at one vehicle width direction side relative to a vehicle width direction center position of the vehicle, and a second breakage initiation point at a position at the other vehicle width direction side. The first breakage initiation point is a region at which bending yield strength is lower than other regions of the bumper reinforcement. The second breakage initiation point is a region with lower bending yield strength than the other regions but higher bending yield strength than the first breakage initiation point. The bumper reinforcement includes a bumper reinforcement main body with a chamber structure and a bracing member inside the bumper reinforcement main body at the vehicle width direction center position of the vehicle.
US12060010B2
A vehicle can include a window including an interior side and an exterior side. The vehicle can include a camera located on an exterior of the vehicle. The camera can be operatively positioned to capture visual data of a blind spot of an external environment of the vehicle. The vehicle can include a dual-sided transparent display forming at least a portion of the window. The vehicle can include a processor operatively connected to the camera and the dual-sided transparent display. The processor can be configured to selectively cause the dual-sided transparent display to display exterior visual information on the exterior side. The processor can be configured to selectively cause the dual-sided transparent to display interior visual information on the interior side. The interior visual information can include the visual data of the blind spot of the vehicle.
US12060000B2
The LED steering wheel cover is a steering wheel cover that consists of LED (light emitting diode) lights with various colors and patterns. The lit up colors and patterns by the LEDs are controlled by the controller that is attached to a steering wheel cover. The LED steering wheel cover uses a wireless remote controller or a wired controller or the LEDs can be preprogrammed. The controller may be programmed to allowed the LED to change the patterns (flashing, cascade, S-O-S, etc.) or color, adjust the brightness of the LEDs, and adjust the speed of the patterns.
US12059987B1
A seat cover for a vehicle may include a lower or bench portion sized and configured to extend over a horizontally-oriented top of a bench of a vehicle seat. The lower portion may include a first section and a second section separated by a slit. The seat cover for the vehicle may also include an upper or backrest portion coupled to the lower portion. The upper portion may be sized and configured to extend upwardly over a backrest of the vehicle seat. The seat cover may be divided into vertical sections that correspond to the seats of a bench seat in a vehicle. One or more of the vertical sections may be removable to accommodate movement of the vehicle seats.
US12059982B2
A seat position adjusting device for a vehicle may integrate a seatback reclining mechanism and a mechanism for realizing a comfort relaxation posture into one simplified mechanism. The seat position adjusting device includes: a seatback frame and a seat cushion frame connected to each other at a predetermined seating angle; a fixed rail mounted on a bottom surface of a rear end portion of the seat cushion frame to be inclined upward and forward; a moving rail mounted to the fixed rail to be movable forward and backward; a pair of support frames mounted on a floor panel; a front link hinge-coupled between a bottom surface of a front end portion of the seat cushion frame and a front end portion of an associated one of the support frames; and one or more support links hinge-coupled between the moving rail and the associated one of the support frames.
US12059978B2
An assembly of a vehicle comprises a floor assembly stationarily arranged in the vehicle and an adjusting device for longitudinally adjusting a vehicle seat in the vehicle comprising a guide rail connected to the floor assembly and extending along a longitudinal axis on the floor assembly, and an adjustment assembly associated with the vehicle seat, which is guided on the guide rail along the longitudinal axis. It is provided that the guide rail includes at least one connecting element which includes an engagement portion for a form-fitting engagement into an engagement device arranged on the floor assembly on a first side of the guide rail and a connecting portion with a fixing point for fixing the connecting element to the floor assembly by using a fixing element on a second side of the guide rail facing away from the first side.
US12059971B2
Various electric scooters are disclosed that include a battery receptacle configured to releasably retain a rechargeable battery therein. The electric scooter may include a deck and a strut extending between the deck and a rotatable shaft connected to a handlebar assembly. The battery receptacle may be supported by the strut, and the battery may be insertable into and removed from the battery receptacle through translation of the battery in a direction substantially parallel to a longitudinal axis of the strut. The battery may be configured for use in a power tool in addition to the electric scooter.
US12059968B2
A wheel and wind power electric generator for a motor, comprising: an alternator that rotates with a wheel of a motor vehicle powered by an internal combustion engine, by an electric motor, or by other mean; an armature of an alternator that rotates with windvanes that rotate in an opposite direction from the wheel when the wheel is in motion, wherein the windvanes are spirally curved, so that they are concave in the direction that the wheel turns when the vehicle is going forward, causing the rotor and armature in the alternator to rotate in an opposite direction from the alternator to generate electricity, and the wheel and the windvanes are covered by a hubcap having slots through which air can move in when the vehicle is moving, causing the windvanes to rotate. The electricity generated may be stored in a capacitor or battery, and/or transferred to a power grid.
US12059967B2
A plug connection system that autonomously charges an electric vehicle (EV) is provided. The method includes: adjusting configuration settings of an image capturing device; capturing an image using the image capturing device, wherein a portion of the image comprises an optically distinctive object associated with a charging portal of the EV, and wherein the image comprises a plurality of pixels; applying a pixel value threshold associated with a pixel metric to the image to filter the plurality of pixels of the image to a first subset of pixels; determining, based on filtering the plurality of pixels to the first subset of pixels, a location of the optically distinctive object associated with the charging portal of the EV within the image; and providing information to maneuver a robotic arm to a physical position associated with the location of the optically distinctive object within the image.
US12059964B2
A charging adapter includes a hitch adapter assembly including a tube that is received in a trailer hitch of a vehicle, a mounting plate coupled to the tube, and an electric vehicle socket coupled to the mounting plate. The electric vehicle socket receives power from an electric vehicle charging station. The hitch adapter assembly is coupled to a mobile or fixed power storage device in the vehicle via a wire or power cord. The power cord conveys power from the electrical vehicle charging station to the power storage device. The power storage device stores the power for use at a selected location and time.
US12059956B2
Systems and methods are provided to perform a vehicle function. A vehicle function command is detected and it is determined if an event moved is active. In response to a determination that the event mode is active, an event mode parameter is retrieved. Otherwise, in response to a determination that the event mode is not active, a normal mode parameter is retrieved. The vehicle function is performed based on the retrieved event mode parameter or normal mode parameter.
US12059953B2
A composite tank for a reusable launch vehicle comprises a composite wall, having a first coefficient of thermal expansion. The composite wall comprises a first end, a second end, a central axis, which passes through the first end and through the second end, and a cylindrical interior surface. The composite tank also comprises slosh baffles, formed from a second material, having a second coefficient of thermal expansion that is different from the first coefficient of thermal expansion. Each of the slosh baffles is attached to the cylindrical interior surface of the composite wall. Each of the slosh baffles is annular and is separated from the cylindrical interior surface of the composite wall by a radial gap, selected, in part, based on a difference between the first coefficient of thermal expansion and the second coefficient of thermal expansion. The radial gap is configured to change responsive to changes in temperature of the composite tank.
US12059951B2
An energy-store floor assembly for a motor vehicle includes an electrical energy-store device which has a plurality of battery modules and is accommodated in a multi-part store housing and arranged on the bottom side of a vehicle floor of the motor vehicle. In order that the store housing can be adapted to the shape of the motor vehicle body and/or to components of the energy-store device in an improved way, housing parts of the store housing are interconnected by at least one gas-tight connection, which has an uneven course with respect to the vehicle vertical direction in at least one length region.
US12059949B2
An electrical component module is installed in a front section of a vehicle, and connected with a battery unit storing electricity for driving the vehicle. The electrical component module is supported by a vehicle body structure member (cross-member) extending in a lateral direction of the vehicle. The cross-member is closer to a passenger compartment than the electrical component module, and doesn't overlap with the electrical component module when viewed along any horizontal direction perpendicular to a vertical direction of the vehicle. Between the cross-member and the electrical component module, provided is a release mechanism for releasing the support of the electrical component module by the cross-member when receiving an impact from an opposite side to the passenger compartment.
US12059948B2
A kart having a pedal speed controller and other components and arrangements thereof are disclosed. The kart can be provided with a controller for controlling speed; the pedal speed controller comprising a pedestal and a pedal, one end of the pedal is articulated with the pedestal and keeps a certain angle with the pedestal. The pedal speed controller also comprises a sensor connected with the controller, and the sensor can obtain displacement signal along the tread direction of the pedal. The pedal speed controller has the advantages of realizing pedal control of acceleration or deceleration for drivers, avoiding interference with manual adjustment of kart direction, preventing from mutual influence between speed regulation and steering, improving the speed control performance of the kart, and improving the driving experience.
US12059942B1
A system for indicating on an electronic device that the refrigerant being introduced by a user to an air conditioning system has reached its optimum fill level includes a sensor device having a main body, the sensor device being structured and disposed for measuring a range of data; a wireless transmitter on the sensor device, the wireless transmitter being in communication with the electronic device for wirelessly transmitting the range of data to the electronic device; an electronic application configured for use with the electronic device; and wherein the electronic application is structured and disposed for visually indicating to the user via the electronic device the transmitted range of data in real time and audibly indicating to the user via the electronic device when the transmitted range of data reaches a predetermined value.
US12059930B1
A pressure management system for a tire assembly on a vehicle including: a housing unit, a pump, and a power interface.
US12059928B2
A pneumatic tire of the embodiment including two main grooves provided on a tread and extending in a tire circumferential direction; a center land portion formed between the two main grooves and extending in the tire circumferential direction; a pair of shoulder land portions formed between a ground contact end and the main groove; a center auxiliary groove provided on the center land portion; and a shoulder auxiliary groove provided on the shoulder land portion, in which the center auxiliary groove has a groove width narrower than that of the main groove and extends in the tire circumferential direction, and the shoulder auxiliary groove has a groove width narrower than that of the main groove and extends in the tire circumferential direction.
US12059927B2
A wheel that deforms to absorb force is provided. The wheel includes one or more deformable spokes that extend from a central portion of the wheel to an outer portion of the wheel. The spokes are configured to interface against neighboring spokes after a spoke is sufficiently deformed. The neighboring spoke provides some support to the deformed spoke, thereby requiring an increased marginal force to further deform the first spoke. In one embodiment the wheel includes a plurality of pairs of spokes that are configured to interface against each other.
US12059920B2
A combination of a paint bucket of traditional size with a paint bucket grid and paint roller with a roller cover attached is described wherein the grid and the paint roller can be stored in the bucket without the handle extending above the brim of the bucket and the roller cover not touching a shallow pool of liquid paint in the bottom of a cavity of the bucket.
US12059915B2
A thermal transfer image receiving sheet includes: a substrate made of paper; a polyolefin resin layer formed on a first surface of the substrate; an adhesive layer formed on a second surface of the substrate facing away from the first surface; a porous layer formed on the adhesive layer; a foundation layer formed on the porous layer; and an image receiving layer formed on the foundation layer. A surface of the substrate, as defined in JIS B 0601:2001, has a maximum valley (undulation) depth Wv of 2.00 μm or less and a root mean square slope for the waviness WΔq of 0.013 or less. The porous layer has a thickness of 25 μm or more, and a thickness of the polyolefin resin layer is 0.2 to 3.0 times the thickness of the porous layer.
US12059902B2
A printing apparatus includes a printing unit that includes an ejection port surface provided with ejection ports through which liquid is ejected, a wiping unit, a depressurizing unit, and detection unit. The wiping unit has an opening and wipes the ejection port surface by moving in a predetermined direction while the opening abuts against the ejection port surface. The depressurizing unit applies negative pressure to the ejection port surface via the opening. The detection unit detects an ejection state of the ejection ports. After driving the depressurizing unit when the opening abuts against the ejection port surface, the suction operation sucks the liquid from the ejection ports while moving the wiping unit. The suction operation is performed from a first ejection port detected as an ejection-failed ejection port by the detection unit under a suction condition different from suction conditions of the ejection ports other than the first ejection port.
US12059882B2
An embodiment dash isolation pad includes a 3D vertical nonwoven fabric layer having a structure in which wave-type short fibers are vertically arranged, a sound absorption layer on one side or both sides of the 3D vertical nonwoven fabric layer, and an olefin-based powder layer between the 3D vertical nonwoven fabric layer and the sound absorption layer.
US12059881B2
In an embodiment a component assembly includes a plurality of components, a carrier, wherein the components are secured on the carrier by a connecting layer, wherein, for each component, the connecting layer forms at least one supporting structure at which the connecting layer is adjacent to the component, and a sacrificial layer arranged regionally between the components and the connecting layer, wherein one portion of the components is assigned to a first group, wherein a further portion of the components is assigned to a second group, and wherein the components of the first group are different than the components of the second group in respect of a coverage with the sacrificial layer.
US12059869B2
A laminated glazing includes a structural transparent substrate bonded to a glass sheet of 0.5 to 4 mm, intended to constitute an outer surface of the laminated glazing, by an adhesive interlayer of 4 to 10 mm, which successively includes 0.25 to 2.5 mm of a flexible first polymer material having a relaxation modulus at most equal to 2 GPa for relaxation times at least equal to 10 min, at temperatures at least equal to −40° C., in contact with the glass sheet, then a stiff second polymer material having a relaxation modulus at least equal to 4 GPa, for time constants at most equal to 0.1 millisecond and temperatures at most equal to 40° C.
US12059852B2
A composite material molding method includes a first disposition step for disposing a prepreg on a jig molding surface of a molding jig; a first sealing step for airtightly sealing the prepreg by covering the prepreg with a first resin bag; a second disposition step for disposing a breather so as to cover the first resin bag; a second sealing step for airtightly sealing the breather so as to cover the breather with a second resin bag; a first depressurization step for depressurizing a first space sealed by the first resin bag; a second depressurization step for depressurizing a second space sealed by the second resin bag; and a heat-curing step for heat-curing the prepreg by supplying the internal space of a pressure vessel with a steam with a predetermined temperature and a predetermined pressure.
US12059848B2
A production machine for the production of collapsible pouches having a fitment. The machine has a fitment sealing station with an impulse sealing device comprising a first jaw and a second jaw and with an actuator device configured to move the first and second jaws relative to one another between an opened position and a clamped position, as well as a cooling device configured to cool each of the first and second jaws. The fitment sealing station is configured to perform an impulse sealing cycle.
US12059842B2
A print head for an additive manufacturing includes a heating chamber for melting an additive manufacturing ink in a form of a filament, the heating chamber including a nozzle for extruding a molten additive manufacturing ink, and a filament inlet for being connected to a filament supply line; the print head further includes a cover outside the heating chamber and movable relative to heating chamber between a first position, wherein in the first position the nozzle is covered by the cover, and a second position, wherein in the second position the cover is distant from the nozzle such that the nozzle is not covered by the cover. The cover comprises a flexible surface to partly deform at contacting with the nozzle when in the first position. An additive manufacturing device with the print head is also provided.
US12059834B2
A system, that includes a container, that includes a first container opening, a liner disposed in the first container opening, a pump connected to the container, and a controller, where the controller is programmed to perform a method for filling the container with the liner, that includes making a first determination that a power on condition is satisfied, in response to the first determination, providing power to the pump, and after providing the power to the pump, making a second determination that a power off condition is satisfied, and in response to the second determination, cutting the power to the pump.
US12059832B2
A concrete dowel placement system and methods for making the same. The system allows for accurate and easy substantially-parallel or parallel placement of slip dowels within sections of concrete so that adjacent sections of concrete may be allowed to undergo thermal expansion and contraction while remaining in a common plane without cracking or faulting. The system includes a coupler and a sheath. The sheath is configured to be slidably extensible over the coupler and may be held to the coupler by friction. An outer surface of the sheath may be textured. Additionally, a method of constructing the concrete dowel placement system includes extruding material to form two tubes of different sizes. The tubes are then attached to each other, then material is extruded or injection molded to form a sheath. Alternatively, construction may include extruding material to form a tube, then removing some of the material from the tube in order to form a coupler.
US12059831B2
To provide a biaxially-oriented polyester film roll that is excellent in transparency and heat resistance and has less defects. A biaxially oriented polyester film roll of the present invention characterized by satisfying requirements (1) a winding length of the film roll, (2) a width of the film roll, (3) an average hardness of an outermost surface layer of the polyester film roll, (4) a variation in hardness, (5) a thickness of a polyester film of the polyester film roll, and (6) an irregularity of thickness in the maximum concave portion.
US12059826B2
A method for manufacturing shaped polymers of surface-active macromolecules, in particular silk, is provided. The method is comprising the steps of: • a) depositing an aqueous solution of the surface-active macromolecules on a surface, wherein the aqueous solution of the surface-active macromolecules is deposited in the form of a droplet, and wherein the surface is a hydrophobic micropatterned surface adapted to prevent the aqueous solution from penetrating into the pattern and to receive the droplet of the aqueous solution of the surface-active macromolecules and retain its droplet state; and • b) forming shaped polymers of the surface-active macromolecules on the surface.
US12059825B2
A manufacturing method of a structure by which a target member can be easily positioned with high accuracy. In a tilting step, at least one target member is positioned by tilting a positioning table and sliding the target member placed on the positioning table to bring the target member into contact with a locking portion.
US12059811B2
An automated palletizer for building a mixed case pallet, the automated palletizer including a case infeed that feeds mixed cases to provide an input queue feed sequence of mixed cases. At least one pallet building robot communicably connected to the case infeed and configured to receive the mixed cases in the input queue feed sequence of mixed cases, and place the mixed cases according to and dependent on the input queue feed sequence of mixed cases so as to effect building the mixed case pallet at a predetermined substantially steady placement rate. A controller communicably connected to the case infeed and at least one pallet building robot, and being configured so as to generate a complete and stable mixed case arrangement plan that completes at least a predetermined whole part of the mixed case pallet and that describes a predetermined planned location and pose for each case.
US12059807B2
A method for force or torque sensing in an electromechanical actuator-driven robot comprising one or more links, one or more joints, an end effector and a controller is provided, the method comprising: estimating a first set of load torques in one or more joints in a given configuration of the robot without external force or load applied to the end effector; identifying gravitational and frictional components in the first set of load torques; estimating a second set of load torques in the one or more joints in the given configuration of the robot with an external force or load applied to the end effector; calculating a difference between the second set of load torques and the first set of load torques, taking into account the identified gravitational and frictional components; calculating an external force or torque acting on the end effector based on the difference between the second set of load torques and the first set of load torques using a Jacobian matrix for the given configuration of the robot; and presenting the external force or torque in a Cartesian space. An apparatus for force or torque sensing in an electromechanical actuator-driven robot, the apparatus comprising at least one processor programmed to perform said method, a computer program which, when executed by at least one processor, causes the at least one processor to perform force or torque sensing in an electromechanical actuator-driven robot according to said method, and a non-transitory storage medium for storing said program are also provided. The technical result consists in improved precision of force or torque sensing on an end effector of an electromechanical actuator-driven robot in a manner which does not require using expensive force/torque sensors in robot joints.
US12059799B2
A tool arrangement includes a tool management device with a body and a lid, wherein the lid, by a hinge connection, is configured pivotably for selectively covering or releasing a receiving space of the body relatively to the body, and a receiving device for receiving tool elements which is mounted or mountable in the receiving space of the body. By the hinge connection, the receiving device is co-pivoted when the lid is pivoted. The hinge connection includes at least one pin and the lid has at least one slide guide for guiding the at least one pin along a pregiven trajectory.
US12059797B2
A tool with a segmented tool handle includes a first tube, a second tube and a limiting seat. The first tube has a first inner hole and a first fastening hole. The second tube has one end inserted into the first inner hole, a second inner hole and a second fastening hole. The limiting seat is disposed in the second inner hole and connected with a fastener. An end of the fastener is threadedly connected to the limiting seat and the other end of the fastener has a conical abutting portion. The abutting portion abuts against an inner periphery of first fastening hole when the fastener is in a fastened position. The abutting portion detaches from the first fastening hole when the fastener is in a unfastened position.
US12059791B1
A pneumatic tool has an air outlet chamber, at least one forward channel, a rear transmission spacing, at least one washer channel, at least one shaft channel, at least one bushing channel, and a front transmission chamber sequentially communicating with one another. Compressed air for driving the pneumatic motor flows into the air outlet chamber, and then flows forwardly to the front transmission chamber through the at least one forward channel, the at least one washer channel, the rear transmission spacing, the at least one shaft channel, and the least one bushing channel, sequentially. Heat produced by the pneumatic tool is continuously carried by the compressed air flowing forwardly, thereby dissipating the heat and cooling the transmission set.
US12059782B2
A paint roller sleeve removal tool for overlying an unwanted roller sleeve to allow a user to remove a soiled roller sleeve without spreading mess undesirably. The paint roller sleeve removal tool includes a primary tubular member having a first primary panel hingedly affixed to a second primary panel. The secondary tubular member is affixed to the primary tubular member, the secondary tubular member having a first secondary panel is affixed to a distal end of the first primary panel and a second secondary panel is affixed to a distal end of the second primary panel. The paint roller sleeve removal tool includes a plurality of protrusions that are affixed to an interior surface of each of the first primary panel, the second primary panel, the first secondary panel, and the second secondary panel.
US12059780B2
A tool storage system includes a tool storage container configured to receive therein a battery for a power tool with an inductive receiving unit. An inductive transmitting unit is coupled to the tool storage container and configured to receive a source of electrical power. The inductive transmitting unit is configured to induce generation of electrical power in the inductive receiving unit to charge the battery. A controller is configured to control generation of electrical power by the inductive receiving unit based on a position or alignment of the inductive receiving unit relative to the inductive transmitting unit.
US12059778B2
A transducer assembly for use in a power tool including a housing, a motor, an output shaft that drives a workpiece about a central axis, and a transmission. The transducer assembly includes a transducer positioned between the motor and the transmission. The transducer including an inner hub being rotationally affixed to the housing, an outer rim affixed to a rotatable component of the transmission, a plurality of webs extending radially outward from the inner hub to the outer rim, and a sensor affixed to each of the webs for detecting strain of each of the webs in response to a reaction torque applied to the transmission from the output shaft. A width of each of the webs gradually tapers from at least one of the outer rim or the inner hub toward a midpoint of each of the webs in a direction perpendicular to the central axis.
US12059773B2
Systems and methods include providing a coated abrasive article with a substrate formed from a plurality of hygroscopic fibers, an abrasive layer comprising a make coat, a size coat, a supersize coat, or combinations thereof disposed on a first side of substrate, and an anti-curl layer disposed on a second side of the substrate. The polymer-based anti-curl layer allows the coated abrasive article to achieve a change in curl between −5 millimeters and 25 millimeters, the change in curl being expressed as the curl of the coated abrasive article in millimeters at 90% relative humidity minus the curl of the coated abrasive article in millimeters at 20% relative humidity. The coated abrasive article exhibits substantially no loss of grinding performance, burst speed, or a combination thereof as compared to coated abrasive articles free of the anti-curl layer.
US12059772B2
The disclosure identifies an apparatus, system of and method for using an interchangeable fluid jet tool, the tool in at least one embodiment being a waterjet tool device that may be interchangeably integrated with a machine having any form of reciprocating or rotating pump (which may be used as a coolant or cutting fluid pump), and coupled with a motor powered rotatory drive machine, such as a spindle, having any type of tool interchange attachment and tool holders.
US12059770B2
According to an aspect of the present disclosure, there is provided a washing device that washes a barrel tank of a horizontal centrifugal barrel polishing device. The washing device includes a casing, a rotation mechanism, a washing nozzle, and a nozzle moving mechanism. The casing includes a frame to accommodate the barrel tank, and a rotary shaft extending from the frame. The rotation mechanism is a mechanism to rotate the frame around the rotary shaft. The washing nozzle is a nozzle to eject washing water. The washing nozzle is configured to be insertable into and removable from the barrel tank. The nozzle moving mechanism moves the washing nozzle in a direction where the washing nozzle is inserted into and removed from the barrel tank.
US12059762B2
In a system for automatically manufacturing a pipe spool, when information on a pipe spool is input to a control unit, manufacturing of a spool pipe by cutting an original pipe, processing of a spool pipe, processing of a connection member, manufacturing of a straight pipe spool by welding a spool pipe to a connection member, and manufacturing a three-dimensional spool by welding a straight pipe spool to the other straight pipe spool or a connection member may be automatically performed by a sensor, an automatic device or a robot included in each process and the control unit connected to each of the devices.
US12059761B2
Platform for conveying work parts in an assembly line, and method for placing work parts on the same
Disclosed herein is a platform for conveying a plurality of work parts in a sequence of manufacturing stations, the platform being mobile and including an inclined surface, and a set of two elements, one element of the set extending along a first plane and another element of the set extending along a second plane, an intersection of the first plane with the inclined surface defining a first direction, an intersection of the second plane with the inclined surface defining a second direction, the first direction and the second direction delimiting an angular sector, so that a work part placed on the inclined surface within the angular sector is driven by its weight downwards with respect to a slope of the inclined plane towards an intersection of the first direction and the second direction.
US12059752B2
Engine-driven welding-type power supplies with portable welding units are disclosed. An example engine driven welder includes an engine, a generator configured to convert mechanical power from the engine to electric power, a chassis, the engine and the generator being mounted to the chassis, and a welding power supply configured to receive the electric power from the generator and convert the electric power to welding-type power, wherein the chassis is configured to physically hold the welding power supply, the welding power supply is physically separable from the chassis, and the welding power supply is connected to be able to receive the electric power when the welding power supply is separated from the chassis and when the welding power supply is connected to the chassis.
US12059751B2
A system for generating a G-code for controlling an operation of a laser-cutting machine to cut parts from a sheet of material, upon receiving cutting data specifying a cutting order of parts and a cutting order of edges of each part, tests the parts for potential distortions and generates a G-code to avoid the potential distortion. For testing a current part, the system detects a potential distortion when the final edge of the current part is adjacent to an edge of a previously cut part scheduled for cutting before the current part according to the cutting order of parts. The system modifies the cutting order to select the modified cutting order for which the final edge is not adjacent to any edge of any previously cut part.
US12059746B2
An apparatus for forming a laser beam can include a controllable spatial light modulator, a control device for controlling the light modulator, and a beam guiding optical unit, wherein the control device is configured to split a display plane of the light modulator into a plurality of display regions and to represent a first beam influencing structure in at least one first display region of the plurality of display regions and a second beam influencing structure in a second display region of the plurality of display regions, wherein the beam guiding optical unit is configured to cause the laser beam to interact along the direction of propagation thereof firstly with the first display region and then with the second display region.
US12059745B2
A device is provided for setting a focus position (z) of a laser beam in a laser machining system. The device comprises a computing unit configured to calculate a time-dependent value zt of the focus position (z), wherein the computing unit calculates the time-dependent value zt of the focus position (z) based on a first parameter and a second parameter, wherein the first parameter indicates a magnitude A of a laser-power dependent focus shift per power unit and the second parameter indicates a time constant τ of a change in focus position due to a thermal lens by a factor of 1/e, and a control unit configured to use a mechanism for setting the focus position (z) to set the focus position (z) of the laser beam based on the time-dependent value zt of the focus position (z).
US12059743B2
An apparatus for laser machining is provided including a stage for supporting a substrate and a controller for generating an error compensation table, a motor driver for moving the stage, and an error compensation unit for generating a table to compensate for an error. The error compensation unit includes a grid plate disposed on the stage and an imaging unit for imaging the grid plate. The motor driver outputs a position synchronization signal to the imaging unit according to a position of the stage. The imaging unit receives the position synchronization signal from the motor driver and images the grid plate while moving the stage.
US12059741B2
A method for manufacturing a liquid cooling jacket has a feature of using a primary joining rotary tool provided with a tip side pin and a base side pin having a taper angle larger than a taper angle of the tip side pin and comprising a first primary joining process in which inserting the tip side pin and the base side pin of the rotary tool that is rotating into the sealing body member and moving the rotary tool along the first abutted portion with an outer circumferential face of the base side pin being in contact with a front face of the sealing body member and with the outer circumferential face of the tip side pin being kept off a step side face of the peripheral wall step portion while having a second aluminum alloy of the sealing body member flow into the gap.
US12059737B2
A power tool includes a tool accessory, a motor, a control module, a power supply, and an operating switch. The operating switch includes a trigger mechanism, a current switch coupled to the trigger mechanism to be actuated by the trigger mechanism for connecting and disconnecting the electrical connection between the power supply module and the motor, and a signal switch coupled to the trigger mechanism to be actuated by the trigger mechanism at least configured to output a control signal to the control module to control the start of the motor.
US12059736B2
A cutting grinder for cutting through a rail of a track includes a detection device for detecting a proposed cutting position. The cutting grinder guarantees simple, user-friendly and efficient through-cutting of the rail.
US12059735B2
Provided is a structure for improving accuracy in attaching a cutting tool to a body and making it possible to increase the number of blades while the cutting tool is mounted on the body. A cutting insert 1 includes: an upper surface 10 that has a shape with a lengthwise direction LD and a widthwise direction SD; a lower surface that is located opposite to the upper surface 10; a peripheral side surface 30 that is formed so as to connect the upper surface 10 and the lower surface; cutting edges 51 and 52 that are respectively formed on an intersecting ridge line of the upper surface 10 and the peripheral side surface 30, and on an intersecting ridge line of the lower surface and the peripheral side surface 30, and each have a curved ridge line that extends in a lengthwise direction thereof; and a through hole 60 that penetrates from the upper surface 10 to the lower surface. End surfaces 31 and 32 located in the lengthwise direction LD of the upper surface 10 and the lower surface, of the peripheral side surface 30, are respectively inclined with respect to the upper surface 10 and the lower surface, and are parallel to each other. A reference surface 33 that is located opposite to the cutting edges 51 and 52, of the peripheral side surface 30, is a flat surface that is orthogonal to the upper surface 10 and the lower surface.
US12059733B2
A smart power tool includes: an output shaft, an electric motor, a housing, and an adjustment assembly. The adjustment assembly is used for adjusting a working mode and outputting a mode signal. The working mode includes a drill gear mode and a wood screw mode. In the drill gear mode, a working state of the smart power tool is determined according to a set of current variables and/or a set of feature quantities and a type of a drill bit and, when the smart power tool is in a drill-through state, the electric motor is controlled to stop rotating.
US12059732B2
Machine chuck jaws, and a related method of manufacture, are provided. The machine chuck jaws are formed from an additive manufacturing process and include one or more gripping pads per chuck jaw. An axial stop is also formed from an additive manufacturing process and provides a flat surface for workpiece placement. The gripping pads equally distribute the clamping pressure, and the additive manufacturing process provides unique shaping capabilities and a honeycomb internal cross-section, thereby achieving a lightweight design. The reduction in weight allows for a decrease in pneumatic pressure used to actuate the jaws, resulting in a corresponding reduction in the clamping pressure which helps improve the form of the workpiece being machined.
US12059726B2
A method for forming a component includes estimating a dosing plan for powder of a powder bed fusion (PBF) system needed to form the component. The dosing plan includes powder dosing requirements needed per layer to form the component. The method includes providing the dosing plan to a controller of the PBF system. Further, the method includes regulating the powder being supplied to a build chamber of the PBF system from a supply chamber of the PBF system based on the dosing plan. In addition, the method includes additively manufacturing the component via the PBF system using the powder.
US12059722B2
A clamping method includes a step (S3) for applying, by a first support portion disposed on one surface side of a plurality of superposed members and a second support portion disposed on the other surface side of the plurality of members, a predetermined first pressure to the plurality of members, and sandwiching the plurality of members; a step (S4) for forming a through hole with respect to the plurality of members by a cutting tool with the first pressure; a step (S5) for applying a predetermined second pressure to the plurality of members after the through hole is formed, and sandwiching the plurality of members by the first and second support portions, the second pressure being lower than the first pressure; and a step (S6) for fixing a fastening part inserted into the through hole to the plurality of members by a riveting device with the second pressure applied.
US12059719B2
Various storage containers are described for retaining drain cleaning cables. Storage systems utilizing the containers with a cable guide assembly are further described. Also described are methods of using the containers and systems.
US12059718B2
The invention relates to an apparatus for producing a can packaging blank by backward extrusion. The apparatus has a die wall and an extrusion punch, wherein the die has a die base and a die wall having a die wall height HG. The die wall has, in the region thereof adjacent to the die base, at least one protrusion having predetermined width (B), predetermined height (H), predetermined depth (T) and predetermined cross-section, wherein the height (H) of the protrusion equals 95% of the die wall height (HG) at maximum.
US12059713B2
The present invention relates to a substrate treatment apparatus including: a chuck base rotatably disposed around a rotating shaft; chuck pins disposed on top of the chuck base to fix a substrate thereto; and an ultrasonic cleaning unit disposed on top of the chuck base to perform ultrasonic cleaning for the underside of the substrate.
US12059711B2
Items are sorted into target points that are logically linked to their destination. The target points are arranged in a matrix array and in a first plane. One or more destinations can be logically assigned, at least temporarily, to the target points. First sorting conveyors run in a first direction and have discharge modules which can be actuated by a sorting controller. The conveyors are arranged in a second plane above the first plane and run between rows of target points. The discharge modules in the first sorting conveyors can serve target points on both sides of the sorting conveyors with sorting items intended for these target points. A pre-sorting conveyor with discharge modules is arranged laterally of the array of target points and is controlled to pass a sorting item to the sorting conveyor that serves the target point intended for this sorting item.
US12059708B2
Disclosed herein are ultrasonic transducer systems comprising: an ultrasonic transducer comprising a substrate, a diaphragm, and a piezoelectric element; a first electrical circuitry coupled to the ultrasonic transducer, the first electrical circuitry configured for driving the ultrasonic transducer or detecting motion of the diaphragm; a plurality of electrical ports coupled to the ultrasonic transducer; and a second electrical circuitry connected to two or more of the plurality of electrical ports, the electrical circuitry comprising one or more of: a resistor, a capacitor, a switch, and an amplifier, wherein the second electrical circuitry is independent from the first electrical circuitry, and wherein the second electrical circuitry is configured to dampen the motion of the diaphragm.
US12059707B2
An ultrasound diagnostic apparatus and an ultrasonic probe are provided which are capable of reducing a leak current even in combined use of a low voltage transmission circuit and a high voltage transmission circuit including a buffer. The ultrasonic probe includes: a high voltage transmission circuit for transmitting a relatively high voltage; a low voltage transmission circuit for transmitting a relatively low voltage; and a transducer for selectively receiving a voltage transmitted from the high voltage transmission circuit and the low voltage transmission circuit. The high voltage transmission circuit includes: a current source for varying a current generated thereby and a current drawn thereby based on a set signal; a buffer for driving the transducer in accordance with the currents generated and drawn by the current source; and an impedance controller connected to an input terminal and an output terminal of the buffer.
US12059703B2
A method is provided for coating a surface of a material with a film of porous coordination polymer. A first substrate having a first surface to be coated is positioned in a processing chamber such that the first surface is placed in an opposing relationship to a second surface. The second surface may be provided by a wall of the processing chamber, or in some cases the second surface may be provided by a second substrate to be coated. The first substrate is held such that a gap exists between the first and second surfaces, and the gap is filled with at least one reaction mixture comprising reagents sufficient to form the crystalline film on at least the first surface. A thin gap (e.g., less than 2 mm) between the first and second surfaces is effective for producing a high quality film having a thickness less than 100 μm. Confining the volume of the reaction mixture to a thin layer adjacent the substrate surface significantly reduces problems with sedimentation and concentration control. The size, shape, or average thickness of the gap may be adjusted during formation of the film in response to feedback from at least one film growth monitor.
US12059699B2
Various examples are provided related to low pressure delivery, e.g., less than 250 psi at the point of application, of plural component system from unpressurized parts A and B material supplies. In one example, a system includes a polyurethane spray foam (“SPF”) raw material supply including parts A and B and a fluid handling system that can deliver the SPF raw material at low pressure to a metal spray gun in metered amounts through separate material fluid paths/conduits via a heated hose length and a whip hose. The fluid handling system can also deliver air at low pressure to the spray gun through separate air stream paths so that the air is communicated to the part A and B material conduits forward of the part A and B material input locations, where they are supplied separately to a mixing nozzle that is engaged at an end of the spray gun.
US12059697B2
A high-pressure washer has a housing and an actuator rotatably supported about an actuator rotation axis. A control element is arranged rotatably at the housing and is provided to control the actuator. The control element and the actuator are fixedly connected to each other for joint rotation by one or more universal joints.
US12059694B2
A pumping device (100), comprising a movable part and a fixed part. The movable part is capable of reciprocating relative to the fixed part, thereby dispensing, by means of a straw (30) connected to the fixed part, a product contained in a container (20). The pumping device (100) comprises elastic members (150, 250, 350, 550, 650, 850, 950, 1050), one end of each of the elastic members (150, 250, 350, 550, 650, 850, 950, 1050) is connected or supported on the movable part, and the other end of each of the elastic members (150, 250, 350, 550, 650, 850, 950, 1050) is connected or supported on the container (20), or is supported on the container (20) by means of the fixed part. The pumping device (100) having the described structure allows the elastic members (150, 250, 350, 550, 650, 850, 950, 1050) to be fabricated using plastic, and is also capable of obtaining the required elasticity.
US12059689B2
An air conditioning apparatus is provided. The air conditioning apparatus includes: a filter configured to have a first conductor layer, an insulating layer having a thickness in the range of 5 nm to 1000 nm, and a second conductor layer which are sequentially stacked, and include a plurality of holes penetrating through the first conductor layer, the insulating layer, and the second conductor layer; a fan assembly configured to suck air from the outside and provide the sucked air to the filter; a power supply device configured to provide alternating current power between the first conductor layer and the second conductor layer; and a processor configured to control the power supply device to selectively vary a frequency or a voltage magnitude of the alternating current power provided to the filter.
US12059687B2
Systems and methods can sort materials of different specific gravities in a mixture. These systems and methods for separation of materials provide multiple forces simultaneously. The system can utilizes both vertical and the horizontal forces for efficient separation of materials with different specific gravities.
US12059685B2
A circular disc element having at least two beam elements. Each beam element extends beyond an outer circumference of the circular disc element in an extension direction which is parallel to a radial direction of the disc element. The circular disc element further includes at least two holes extending through the circular disc element in a longitudinal direction which is substantially perpendicular to each of the extension directions with respect to a circumferential direction of the circular disc element, which circumferential direction corresponds to the outer circumference of the circular disc element. The circular disc element can function as a grinding means in a grinding process for grinding slurry.
US12059683B2
An implement for eliminating headspace in the testing space(s) (T9 or MPWell) of a test tube (T) or microtiter plate (MP), and methods of using such implements to measure oxygen concentration in a test sample. The implement projects into a test chamber (T9 or MPWell) to displace a portion of a fluid sample within the test chamber (T9 or MPWell) and has longitudinally extending grooves (109 and 229) through which the displaced fluidic content can be discharged from the test chamber (T9 or MPWell).
US12059679B2
Devices, systems, and their methods of use, for sorting droplets or particles are provided. A source of acoustic energy can be employed to sort droplets or particles of a desired and predictable property.
US12059664B2
A method of producing a substance includes a producing step of producing a new substance by, in a state in which a raw material absorbing giant pulse laser light is disposed inside a base material or in a state in which the base material and the raw material are brought into contact with each other and are clamped together, performing irradiation with the giant pulse laser light such that the raw material absorbs the giant pulse laser light and thereby generating shock waves such that at least the raw material undergoes phase transition.
US12059662B2
Described herein are coated chloride salt particles, including NaCl/TiO2 and NaCl/SiO2 core/shell particles, along with methods of making and using the same.
US12059661B2
A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.
US12059650B2
A wirelessly controlled device for atmospheric water generation is provided. The device comprises an atmospheric water generator for generating filtered potable water and a wireless external control system. The wireless external control system comprises one or more display presentation pages for displaying a plurality of operating parameters for the atmospheric water generator, including content display with a variety of operation parameters and historical water collection data for operation of the atmospheric water generator. The wireless external control also has one or more display pages configured for user input for a user to select one or more water generation parameters for operation of the atmospheric water generator. Once the device is directed by the wireless external control system to generate water, the device is capable of automatic water generation until the device fulfills the one or more set water generation parameters.
US12059646B2
An adsorption apparatus and associated method for capturing a target gaseous adsorbate from an atmospheric air based gaseous feed stream. The adsorption apparatus includes a housing enclosing at least one adsorption element for adsorbing the target gaseous adsorbate, at least one substrate coated with an adsorptive composite coating that comprises at least 50 wt % metal organic framework and at least one binder, the housing having an inlet through which the gaseous feed stream can flow to the adsorption element and an outlet through which gas can flow out from the housing; and a desorption arrangement in contact with and/or surrounding the at least one adsorption element.
US12059644B2
A fluid filtration device containing a composite filter media having a coarse porous polymeric nonwoven interlayer located between first and second polymeric fiber containing filter mats. The fiber diameters of the fibers in the first and second filter mats are different from each other, and each filter mat has a different pore size rating. The first and second polymeric fibers in the filter mats can be electrospun nanofibers. The interlayer has a coarser pore size when compared to the either the first or second filter mats, such that the resulting composite media has an increased dirt holding capacity compared to filter layers that are layered directly over each other without the presence of a coarse interlayer therebetween.
US12059641B2
A vapor distributor for use in an internal region of a mass transfer column to receive and redistribute a vapor stream when it is introduced radially into the internal region through a radial inlet in a shell of the mass transfer column. The vapor distributor includes a plurality of multiple-sided elongated deflectors arranged in a descending array and a pair of braces that extend longitudinally across the array of elongated deflectors and hold them in spaced apart and side-by-side relationship to each other. Each of the elongated deflectors has a deflecting surface that faces toward the radial inlet to redirect and redistribute the radially-introduced vapor stream. The braces each include a strut that may also redirect and redistribute the vapor stream.
US12059634B2
The present invention relates to a method of manufacturing spray-dried powders. During the process, a solvent is used. The process is done in a continuous manner and such that the emulsification mass ratio is low when removal of the solvent is started. Preferred solvents are isopropyl acetate and ethyl acetate. The invention also relates to a set-up to run the inventive process at industrial scale.
US12059633B2
The present invention relates to a method of controlling an ensemble of interacting toy construction models. The interacting toy construction models include toy construction elements having functional toy construction elements, the toy construction elements include coupling members configured for detachably interconnecting the toy construction elements with each other. The functional toy construction elements may perform a function in compliance with a configuration defining a functional behaviour. The method includes configuring the functional toy construction elements in the interacting toy construction models based on information on further functional toy construction elements in said interacting toy construction model to coordinate their functional behaviour in a model-behaviour; and further adapting the model-behaviour based on information on further interacting toy construction models in the ensemble. The invention also elates to a toy construction set for constructing an interacting toy construction model and a toy construction system comprising at least two interacting toy construction models.
US12059632B2
The systems and methods disclosed herein relate to play enhanced with augmented reality, the disclosed systems comprising: a user device, the user device comprising, a camera, and a computer system, the computer system further comprising: at least one processor; a graphical user interface and a computer-usable medium embodying computer program code configured for: collecting at least one frame of video with an image capture module; identifying user controlled objects in the at least one frame of video with an object recognition module, and rendering an augmented reality display on the user device with an augmented reality module, the augmented reality display including an augmented background and a rendering of the at least one user controlled object.
US12059623B2
In a first scene of a game played by users, an information-processing system outputs a first image or a first sound to an output device, the first image or the first sound instructing the users to shoot an image by use of a camera device. Subsequently, the information-processing system acquires color information of second images shot by the users, the color information being calculated based on the second shot images, and determines a designated color based on the color information. After determining a designated color, in a second scene subsequent to the first scene, the information-processing system outputs a third image or a second sound to the output device, the third image or the second sound instructing the users to shoot an image of an object that corresponds to the designated color. Subsequently, the information-processing system provides an evaluation to a fourth image shot in the second scene such that the closer a color of the fourth shot image to the designated color, the higher the evaluation.
US12059619B2
Information processing method and apparatus, computer readable storage medium, and electronic device
Embodiments of this application relate to the field of artificial intelligence technologies, and in particular, to an information processing method, an information processing apparatus, a computer readable storage medium, and an electronic device. The information processing method includes: determining, by a device, a subject in a game scenario, and acquiring an action model used for controlling the subject to execute a game action; performing, by the device, feature extraction on the game scenario to obtain model game state information related to the subject; performing, by the device, mapping processing on the model game state information by using the action model, to obtain model game action selection information corresponding to at least two candidate game actions; and selecting, by the device according to the model game action selection information, a model game action for the subject from the at least two candidate game actions.
US12059618B2
With existing game apps, in the case where the stamina is recovered through time-based recovery to an upper limit value thereof while a user is not playing the game, a message or the like indicating full stamina recovery is displayed on a notification screen of a smartphone. According to the present invention, a terminal device, such as a smartphone, is configured so that a user can receive, from a game app, a push notification indicating full stamina recovery through time-based recovery and can perform an operation for instructing time-based stamina recovery beyond a stamina upper limit value on a screen of the push notification. This makes it possible to execute a game play more advantageously just by performing the operation on the screen of the push notification even when the user cannot afford to spend time for starting the game app and playing the game.
US12059615B2
A virtual-environment-based object construction method and apparatus, and a computer-readable storage medium are disclosed in this disclosure, relating to the field of virtual environment. Performed by a terminal comprising a camera, the method including: displaying an environment interface; receiving a capture operation being used for acquiring three-dimensional (3D) information of a to-be-acquired object; receiving a position input operation for determining a display position of the target object in the virtual environment; and displaying the target object at the display position in the virtual environment according to the capture operation and the position input operation.
US12059611B2
An example game controller is removably attachable to a main unit. The game controller includes a controller-side slide member. The controller-side slide member protrudes from a first surface of the game controller and is configured to slidably engage with the main unit-side slide member in a slide direction. The controller-side slide member has a first end and a second end in the slide direction, and the game controller is configured to be attached to the main unit by inserting the controller-side slide member into the main unit-side slide member. The controller-side slide member includes a protruding portion and at least one terminal. The protruding portion protrudes from the first end side of the controller-side slide member in the slide direction and has a facing surface that faces the first surface of the game controller. The at least one terminal is between the facing surface and the first surface.
US12059610B2
The conspicuity of a light emitting surface provided along an outer edge of an input member is enhanced. An input device (10) includes an upper cabinet section (41) having an opening formed therein, an input member (20) that has an upper surface to be touched by a user with a finger and that is disposed inside the opening, and a light diffusing member (71) having a light emitting surface (E2) located along an outer edge of the input member (20). The light emitting surface (E2) has a first region (71g) exposed in a gap between an inner edge of the opening of the upper cabinet section (41) and an outer edge of the input member (20) and a second region (71h) positioned on an inner side of the outer edge of the input member (20) and below a peripheral portion (21a) of the input member (20).
US12059609B2
A tracking system uses a dynamic vision sensor (DVS) operably coupled to the processor. The DVS has an array of light-sensitive elements in a known configuration. The DVS outputs signals corresponding to two or more events at two or more corresponding light-sensitive elements in the array in response to changes in light output from two or more light sources mounted in a known configuration with respect to each other and with respect to a controller. The output signals indicate times of the events and locations of the corresponding light-sensitive elements. The processor determines an association between each event and two or more corresponding light sources and fits a position and orientation of the controller using the determined association, the known configuration of the light sources and the locations of the corresponding light-sensitive elements in the array.
US12059604B2
Embodiments of a blade style putter type club head comprising enlarged physical features such as an enlarged length, height, and depth. The enlarged physical features, specifically the enlarged length allows mass to be positioned further from the center of gravity. The positioning of the mass away from the center of gravity allows the blade style club head to achieve an increased MOIyy creating a more forgiving blade style putter type club head.
US12059601B2
An inflatable ball (such as a soccer ball) may have an outer shell comprising panels. The panels may include at least one surface texture. At least a subset of the panels may include indentations in addition to the surface texture. The indentations may include a shape which is different from a shape of the surface texture.
US12059595B2
Provided is a squat exercise system and a method for tracking squats performed that includes a bench component which functions as a landing for a user and a remote control system that controls operations performed by the squat exercise system and includes a remote control unit operating the squat exercise system, and a housing removably attached to an underside of the bench component that includes a power supply unit supplying power, a sensing device which senses a body part of the user when within a predetermined distance from the bench component and generates a signal, a processor/control unit that receives and processes the signal by the sensing device in communication therewith, and automatically tracks, in real-time a count of each successful squat completed and a total count thereof, and a notification unit in communication with the processing/control unit that generates a notification signal indicative of successful completion of a squat.
US12059592B2
An exercise bike includes a frame, a rotor assembly and a drive assembly mounted on the frame, where the drive assembly is configured to drive rotation of the rotor assembly, and a cover configured to at least partially cover the rotor assembly. The components of the drive assembly and the rotor assembly include structures that improve the performance of the exercise bike, including but not limited to a strong and rigid construction and improvements in belt tracking, user feel, effort consistency, synchronization, and rotor performance.
US12059586B2
The present invention provides a wireless rechargeable and portable anti-microbial respirator. The respirator includes a face-piece with an air inlet and an air outlet; a first belt and a second belt, the first belt is connected to ends of the face-piece, and the second belt is configured to wrap around the waist of a user; a flexible outlet tube, where the first end of the flexible outlet tube is connected to the air outlet of the face-piece; a flexible intake tube, where the first end of the flexible intake tube is connected to the air inlet of the face-piece; and a filtration system fixed onto the second belt. The key features of the respirator in the present invention include highly antibacterial and antiviral, long duration, reusable, self-cleaning and self-disinfecting, lightweight and portable, wireless power transfer, and great airflow and comfortable breathing.
US12059585B2
A fall arrest system for use with a platform includes a harness configured to be worn by an operator, a first bracket and a second bracket configured to be coupled to the platform, a horizontal support including a first end portion coupled to the first bracket and a second end portion coupled to the second bracket, and a harness adapter coupled to the harness, the harness adapter defining an aperture that receives the horizontal support. The harness adapter is repositionable along a length of the horizontal support.
US12059582B2
A method and system of neural stimulation and imaging of nervous system of a subject. The method includes the steps of providing an interface device operable to generate an ultrasonic beam for neuroniodulation and imaging of a targeted neural structure of a subject, implanting the interface device in the subject, and providing and disposing an external coil array over the targeted neural structure of the subject, wherein the external coil array is wirelessly powering and communicating with the interface device.
US12059566B2
An example of a system for controlling delivery of neurostimulation from a stimulation device to a patient according to a selected neurostimulation program may include a programming device. The programming device may be configured to be communicatively coupled to the stimulation device and to select the neurostimulation program. The programing device may include a user interface and a program selection circuit. The program selection circuit may be configured to receive life factor information indicative of at least one of an environmental factor and a biopsychosocial factor of the patient, to select the neurostimulation program from a plurality of neurostimulation programs based on the received life factor information, to present a recommendation using the user interface based on the selected neurostimulation program, and to receive a user command responding to the recommendation using the user interface.
US12059560B2
The invention concerns a method of forming a medical device, the method comprising: forming a graphene film (100) over a substrate (204); depositing, by gas phase deposition, a polymer material covering a surface of the graphene film (100); and removing the substrate (204) from the graphene film (100), wherein the polymer material forms a support (102) for the graphene film (100).
US12059555B2
An injection device is provided, including a syringe having a barrel and a flange and a backstop configured to be coupled with the syringe adjacent to the flange. The backstop includes an inner surface generally extending around at least a portion of the syringe, wherein the inner surface includes at least one protrusion extending away from the inner surface and configured to engage the flange and/or the barrel to permit or promote airflow through a space between the inner surface and the syringe.
US12059552B2
A system includes one or more processors and one or more processor-readable storage media storing instructions which, when executed by the one or more processors, cause performance of obtaining a first target value for a glucose level of a patient, modifying a glucose setpoint from a second target value to the first target value, and regulating the glucose level of the patient to the modified glucose setpoint based on controlling insulin delivery by an insulin infusion device.
US12059551B2
To detect air in a fluid delivery line of an infusion system, infusion fluid is pumped through a fluid delivery line adjacent to at least one sensor. A signal is transmitted and received using the at least one sensor into and from the fluid delivery line. The at least one sensor is operated, using at least one processor, at a modified frequency which is different than a resonant frequency of the at least one sensor to reduce an amplitude of an output of the signal transmitted from the at least one sensor to a level which is lower than a saturation level of the analog-to-digital converter to avoid over-saturating the analog-to-digital converter. The signal received by the at least one sensor is converted from analog to digital using an analog-to-digital converter. The at least one processor determines whether air is in the fluid delivery line based on the converted digital signal.
US12059549B2
A drug delivery device (1) having a delivery unit (3) including a drug container (6), a liquid flow system (7), a pumping system (8), and a casing (9) enclosing therein the drug container, the pumping system and at least a part of the liquid flow system is disclosed. The drug container has a barrel portion (6a) and a plunger (12) slidably mounted within the barrel portion and sealing the drug (78) within the container at one end of the barrel portion. The drug container is contained within a container receiving cavity (75) of a container casing portion (38) and the container receiving cavity is fluidically interconnected to a fluid outlet (31) of the pumping system (8) in a gas tight manner. The pumping system pumps environmental air into the container receiving cavity (75) thus applying pressure on a back end (73) of the plunger for delivery of a liquid drug.
US12059541B2
The invention relates to a medical fluid drainage device for drainage of edematous tissues comprising at least one pumping element (1, 23, 33), having an inlet and an outlet, at least one outlet member (2) having at least one lumen, connected directly or indirectly to the outlet of said pumping element and connecting said pumping element to a body cavity or to a vessel or to a subcutaneous area, and at least one inlet member (3) connected to said inlet of said pumping element and providing fluidic connection between said edematous tissue and said pumping element, and characterized in that the inlet member comprises at least two inlet lumens (4, 5, 6) connected in parallel to said inlet of said pumping element, each of said lumens (4, 5, 6) contains at least one fluid access region, wherein each fluid access region (8, 9, 10) being adapted to allow simultaneous edematous fluid entry from distinct regions of said edematous tissue.
US12059539B2
Guidewires having conductive elements are described where in one variation, the guidewire may be formed by disposing an insulative layer upon a surface of the guidewire core, and printing one or more conductive traces directly upon a surface of the insulative layer.
US12059537B2
Various embodiments of the present technology are directed to a safety clasp (10) including a clasp base (22); a securing element (32) with a sharp end (33), a piercing section (34) and a support (36); and a clasp body (12) including first and second body sections (12A, 12B) and a recess (13) defined therebetween, the body being adjustable relative to the clasp base and the securing element such that in an open configuration the recess is clear and only the first body section houses the sharp end and in a closed configuration the piercing section bridges the recess and only the second section houses the sharp end. Various embodiments of the present technology are directed to a garment clip (100) including such a safety clasp.
US12059532B2
A control apparatus includes: an acquisition unit configured to acquire first information from a first sensor, the first information including biological information of a user of a bed, the bed including a back section, and a controller configured to determine a timing when the user is to wake up based on the first information. If the user is to wake up, the controller performs at least one of an operation of increasing lightness at the location of the bed and an operation of sending wind toward the bed after increasing an angle of the back section.
US12059523B2
An aerosol-generating device includes an electrical power supply, a cavity structure configured to receive an aerosol-generating article, and a plurality of semiconductor heaters within the cavity structure. Each of the plurality of semiconductor heaters includes a substrate layer and a heating layer on the substrate layer. The heating layer is a continuous layer. The aerosol-generating device includes a controller configured to control a supply of electrical power from the electrical power supply to each of the plurality of semiconductor heaters.
US12059522B2
A cartridge for an e-vaping device enables separate vapors to be formed proximate to separate, respective ends of the cartridge. The cartridge includes multiple reservoirs and separate vaporizer assemblies coupled to separate reservoirs on opposite ends of the reservoirs. The separate reservoirs may hold separate pre-vapor formulations. The separate vaporizer assemblies may draw separate pre-vapor formulations from separate reservoirs towards opposite ends of the cartridge and vaporize the separate pre-vapor formulations via operation of separate heaters proximate to the separate ends. The separate heaters may be independently controlled to independently control vapor formation at the separate ends. The heaters may be controlled to independently control vapor formation rates proximate to the separate ends. The heaters may be controlled to form separate vapors at least one of simultaneously, concurrently, and at different times.
US12059521B2
A chamber body is provided, as regions where the liquid flows, with: an upper region including an area from the inner surface of the upper wall to the introduction pipe; a lower region connected to the outlet port; and a connection region connecting the upper region and the lower region. The inner circumferential surface of the upper region has a larger diameter than the inner circumferential surface of the lower region. As a result of diameter reduction from the connection portion relative to the upper region to the connection portion relative to the lower region, an inclined surface is formed on the inner circumferential surface of the connection region.
US12059518B2
A device for the continuous monitoring of blood characteristic quantities in an external cardiovascular supporting circuit, said circuit including a venous line which conveys blood from the patient to an oxygenator, and along which at least one pump is arranged, and an arterial line which returns blood from the oxygenator to the patient, where said oxygenator comprises at least one blood inlet port connected to said venous line and at least one blood outlet port connected to said arterial line, at least one inlet channel and at least one outlet channel of a work gas intended to supply oxygen to the blood and/or to remove carbon dioxide from the same.
US12059514B2
The present invention relates to a breast shield used in a breast pump configured to pump human breast milk. The breast shield includes a hard base portion including both ends and a sidewall connecting the both ends to include a hollow in the base portion in which the both ends are open and a human mamma is accommodated in the hollow through any one of the both ends, through holes passing through the sidewall, and a soft portion configured to surround an outer surface and an inner surface of the base portion, prevent an airflow through the through holes, and have flexibility.
US12059510B2
A biodegradable matrix for preventing post-surgical adhesions, in particular after soft tissue repair in abdominal surgery within the body of a mammal is disclosed. The matrix includes a top layer made of a first biocompatible polymer material and a bottom layer made of a second biocompatible polymer material. The first polymer material comprises poly(lactic acid) as a main component and the second polymer material comprises as a main component at least one polymer selected from the group consisting of poly(glycolic acid), poly(lactic acid), poly(glycolic acid-lactic acid) and mixtures thereof, wherein the poly(lactic acid)content of the first polymer material is higher than in the second polymer material, and wherein both layers are formed as porous scaffolds with the top layer being hydrophilic, having a water contact angle of less than 75°, and the bottom layer being hydrophobic, having a water contact angle of more than 90°.
US12059504B2
A process for producing superabsorbent particles by polymerizing a monomer solution or suspension, comprising drying of the resultant aqueous polymer gel in an air circulation belt drier, grinding, classifying, and optionally thermal surface postcrosslinking, wherein the aqueous polymer gel is introduced into the air circulation belt drier by means of an oscillating conveyor belt, the underside of the revolving conveyor belt is freed of adhering polymer gel by means of at least one stripper device, and the underside of the revolving conveyor belt is sprayed with water.
US12059503B2
In this specification, a method for the manufacture of solid dosage forms is disclosed. The method includes extruding a plasticized matrix through an exit port of an extrusion channel to form one or more plasticized fibers, structuring said fibers to a three dimensional structural network by patterning on a translating or rotating stage, and solidifying the patterned structure.
US12059495B2
The present invention provides a use of platelet dry powder (PDP) for relieving inflammation or injury in an airway portion, wherein per gram of platelet dry powder (PDP) comprises at least 100,000 platelets.
US12059489B2
An oil-in-water emulsion composition for skin includes 0.2 to 2.5% by mass of polyisobutene having a relative mass in a range of 30,000 to 100,000. The composition is applied to skin except for a lip.
US12059462B2
The present invention provides a composition comprising a universal influenza vaccine antigen and a vaccine adjuvant.
US12059460B2
The invention relates to an immunogenic compound comprising an antigenic peptide having amino acid similarity with a tumor antigen, which antigenic peptide is selected in the group consisting of peptides having amino acid similarity with IL13RA2, the said antigenic peptide being selected in the group consisting of sequences described in the specification.
US12059453B2
Methods and compositions for treating aging-related diseases as well as muscle recovery, prevention of muscle degeneration, and maintenance of muscle are described. The compositions used in the methods include blood plasma and blood plasma fractions derived from blood plasma with efficacy in treating and/or preventing disease.
US12059445B2
An aspect of embodiments of the invention relates to providing novel therapeutic compositions comprising herbal extracts of the plant species Sambucus nigra, Echinacea purpurea, and Centella asiatica. The compositions exhibit increased therapeutic activity for treatment of various inflammatory diseases, in particular, inflammatory diseases of mucosa or skin relative to previously identified compositions. In addition the compositions exhibit increased solubility relative to previously identified compositions. In an embodiment of the invention, the ratio of Sambucus nigra:Echinacea purpurea:Centella asiatica is 7:1:2. An embodiment of the invention provides methods for preparing an aqueous therapeutic composition comprising extracts of the aforementioned plant species, using at least two extractions.
US12059442B2
Provided are means, methods, and compositions effective for obesity treatment using probiotics such as bifidobacteria or lactobacilli. Also, a method of selecting probiotic bacteria having a body fat reducing effect, and a method of selecting responders to probiotic bacteria having an anti-obesity action are provided. Provided is a composition for reducing body fat, or the like, which contains Bifidobacterium and/or lactobacilli as an active ingredient, and is used for a pre-obesity group or an obesity disease including intestinal flora in which the ratio of the phylum Firmicutes to the phylum Bacteroidetes has a high value.
US12059433B2
The present invention relates to a method for treating autism spectrum disorders (ASD) or ASD-like symptom, particularly by administering a zinc ion source and/or a serine component e.g. D-serine or its precursor/analogue, optionally in combination with a mixture of branched-chain amino acids (BCAAs). The present invention also relates to a combination, kit or composition for performing the method for treatment as described herein. Further described is use of a zinc ion source and/or a serine component and optional BCAAs for manufacturing a medicament for treating a symptom or disease characteristics associated with ASD or ASD-associated disorder or as a food supplement for ameliorating relevant symptoms in a subject in need thereof. The present invention further provides an animal model for autistic spectrum disorder (ASD) with deficient CTTNBP2 gene, and a method for identifying an ingredient effective in the treatment of ASD by using such animal model.
US12059430B2
One aspect of the present application relates to a storage stable pharmaceutical composition comprising a sulfated glycosaminoglycan having an average molecular weight ranging from 3,000 to 15,000 Daltons, and a pharmaceutical carrier, where the pharmaceutical carrier is mixed with the sulfated glycosaminoglycan, as well as this composition's use in a method of treating a subject for a medically observable improvement. Another aspect of the present application relates to a process for producing a storage stable purified sulfated glycosaminoglycan.
US12059428B2
The present invention provides methods for treating or suppressing tumor metastasis at a site distinct from the bladder in an individual having a urothelial carcinoma of lower tract, comprising locally delivering to the bladder an effective amount of a chemotherapeutic agent (such as gemcitabine), wherein the chemotherapeutic agent is delivered continuously to the bladder for a sustained period of time (such as at least 24 hours).
US12059425B2
The present disclosure provides compounds and pharmaceutically acceptable salts thereof, and methods of using the same. The compounds and methods have a range of utilities as therapeutics, diagnostics, and research tools. In particular, the subject compositions and methods are useful for reducing signaling output of certain oncogenic proteins.
US12059424B2
The present disclosure relates to pharmaceutical compositions suitable for oral administration, and more particularly to pharmaceutical compositions, including pharmaceutical tablet compositions, containing (2S)-N-{(1S)-1-cyano-2-[4-(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-5-yl)phenyl]ethyl}-1,4-oxazepane-2-carboxamide (Compound A) or a pharmaceutically acceptable salt thereof.
US12059415B2
A nimodipine injection concentrate and diluted formulation comprises nimodipine (base or salt), an effective amount of a hydrophilic surfactant, and a pharmaceutically acceptable carrier for injection which is an aqueous solution substantially free of organic solvent, such that the nimodipine is substantially contained in a concentrated injection solution, suspension, emulsion or complex as a micelle or a colloidal particle or an inclusion complex and the formulation is stable and clear. In certain embodiments, the hydrophilic surfactant is polysorbate 80.
US12059407B2
The present disclosure provides endosomal disruptors, which are useful for facilitating delivery of a macromolecule to the cytoplasm of a cell. The present disclosure provides compositions comprising an endosomal disruptor and a macromolecule. The present disclosure provides methods of delivering a macromolecule to the cytoplasm of a cell.
US12059400B2
Provided is a medical compound including a synthetic flavone derivative, according to the formula (I) with allotment in position C-3 of a group as shown below: wherein at least two of R2-R6 are H, and the remaining are independently selected from: H, OH, R1, OR1, NO2, NH2, NHR1, F, Cl, Br, I, where R1 is a radical.
US12059395B2
An antiseptic solution comprising a pH-dependent antimicrobial agent, the pH-dependent antimicrobial agent having an operative pH range, wherein the solution has a pH on storage that is lower than the operative pH range. Applicators for applying the antiseptic solution and methods of using the antiseptic solution and applicators are also provided.
US12059384B2
A mobility assistance apparatus includes first and second frames positioned on left and right sides of a user; a hinge arm mechanism coupled to the first and second frames; and a securing unit or a walking seat coupled to the frames to transfer at least a portion of the user's body weight from the legs and to transfer weight through the user's hip or pelvis to the first and second frame enabling the user to stand or work for an extended period without requiring the user's arms to hold the frame.
US12059381B2
An adjusting device for vehicles comprising at least one mounting plate and one support plate with a lifting device comprising at least two scissor mountings. The scissor mountings are each arranged at the longitudinal side edge or in a corner region of the mounting or support plate and are vertically adjustable via a drive unit. Each scissor mounting takes the form of double scissors and includes a first, lower scissor element and a second, upper scissor element which are connected to each other at one end via a common rotation pin. The lower scissor element is connected at the other end to the mounting plate, and the upper scissor element is connected at the other end to the support plate via fasteners.
US12059377B2
A stretcher with a heated section, the heated section of the stretcher comprising: two opposing electrically conductive elements positioned at, or towards, opposing sides of the stretcher, wherein the opposing electrically conductive elements are connectable to a power source; an electrically conductive layer in electrical contact with the opposing electrically conductive elements, to heat up when the opposing electrically conductive elements are powered by the power source; such that the electrically conductive layer is X-ray transparent to allow a patient to be X-rayed whilst on the stretcher.
US12059360B2
A device adapted to be positioned between two bone regions, the device comprising a body having a stabilising arrangement configured such that bone growing from one bone region toward the other engages the stabilising arrangement of the device.
US12059356B2
An orthopaedic knee prosthesis includes a tibial bearing and a femoral component configured to articulate with the tibial bearing. The femoral component includes a posterior cam configured to contact a spine of the tibial bearing and a condyle surface curved in the sagittal plane. The radius of curvature of the condyle surface decreases gradually between early-flexion and mid-flexion. Additionally, in some embodiments, the radius of curvature of the condyle surface may be increased during mid-flexion.
US12059348B2
Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.
US12059347B2
In certain embodiments, an implantation accessory for placement at a heart valve annulus location of a patients heart, the annulus having a first axis, the implantation accessory comprising: a first surface; a second axis perpendicular to the first surface; and, a maneuvering system for aligning the first axis and the second axis. In certain embodiments, a removable bioprosthetic heart valve assembly for implantation into an abutment ring attached at a heart valve annulus location of a patients heart, the abutment ring having a first axis, the removable bioprosthetic heart valve assembly includes a bioprosthetic valve for coupling to the abutment ring and a holder. The holder, detachably coupled to the bioprosthetic valve, includes a first surface, a second axis perpendicular to the first surface, and a maneuvering system for aligning the first axis and the second axis. Methods of implantation are also disclosed.
US12059344B2
Described embodiments are directed toward centrally-opening leaflet prosthetic valves having a frame and a leaflet construct. Leaflet frame attachments for prosthetic valves include the leaflet construct being at least partially coupled to a frame outer side by a looped structure.
US12059338B2
The invention relates to a prosthesis (1) comprising a textile (2) of elongate shape defining a longitudinal axis A, and a reinforcing element comprising at least one semi-rigid elongate structure (8) connected to said textile, said structure being substantially parallel to said longitudinal axis A and having a distal end provided with at least one fastening element (4) distinct from said textile and capable of cooperating with a part of a tool (10) that is able to pass through said trocar, in order to temporarily couple said prosthesis to said tool.
US12059335B2
This disclosure describes a membrane configured to guide bone and tissue regeneration for a bone defect. The membrane may comprise a first layer, a second layer, one or more perforations, a binder, and/or other components. The first layer of the membrane may be configured to contact bone. The first layer may include pores configured to promote ingrowth of bone regenerating cells into the first layer. In some implementations, the first layer may be a continuous sheet of microporous material without large perforations. The second layer may be configured to substantially prevent fibrous connective tissue from growing into the bone defect. The second layer may comprise a relatively dense structure. The second layer may be fixedly coupled to the first layer. In some implementations, the perforations may comprise co-axial through-holes having common dimensions through the first layer and the second layer. The perforations may be configured to enhance ossification.
US12059332B2
An absorbent article is described that includes leg elastics that form the outermost edges of the product. The leg elastics can include an increased number of elastomeric strands and can extend outboard of the chassis. In this manner, the leg elastics can form a proper seal with the legs of the wearer without interference and can be visually inspected by a caregiver. Placing the leg elastics outboard of the chassis also provides for an efficient manner of producing the garment by attaching multiple elastic components to the garment along a vertical bonding seam.
US12059331B2
A shaped tampon with a groove pattern and a combination of external shapes varying radially and longitudinally.
US12059330B2
In one example, a medical system may comprise a delivery tube configured to couple to a vacuum source and provide negative pressure to a distal portion of the delivery tube; and a porous body at a distal portion of the delivery tube, the porous body including a first section and a second section removable from the first section.
US12059325B2
Disclosed embodiments relate to apparatuses for wound treatment. In certain embodiments, a negative pressure wound therapy apparatus includes one or more electronic components configured to be incorporated into layers of the wound dressing or integrated on top of the wound dressing. In some embodiments, a negative pressure source is incorporated into the wound dressing. The negative pressure source can be sealed between two moisture vapor permeable cover layers or enclosed in a moisture vapor permeable pouch, and may be received in a recess of an absorbent layer or spacer layer of a wound dressing apparatus.
US12059323B2
Wound dressings for use in cases of a patient suffering a penetrating chest trauma. The wound dressing includes a base layer having a lower surface facing the wound and an upper surface facing away from the wound, and an aperture therethrough for locating over the wound, and a top layer extending over the aperture and at least a part of the upper surface. The base layer is connected to the top layer such that the wound dressing can transition from an open configuration in which the aperture and an area external to the wound dressing are in fluid communication via at least one opening at a perimeter between the base layer and the top layer, to a closed configuration in which the top layer forms a seal over the aperture.
US12059317B2
Semisolid oral dispersions for whitening teeth comprising a hydrophilic discontinuous phase and a hydrophobic continuous phase. The semisolid oral dispersions include a hydrophilic discontinuous phase comprising bleaching agent particles. The semisolid oral dispersions also include a hydrophobic continuous phase comprising petrolatum. The h bleaching agent particles can include peroxide compounds and/or hydrogen peroxide adducts. The bleaching agent particle can have a solubility in water of at least about 20 parts, by weight of the particles, in about 100 parts, by weight, of water.
US12059316B2
Some aspects relate to systems and methods for dental treatment and verification. An exemplary system may include a laser configured to generate a laser beam as a function of a laser parameter, a beam delivery system configured to deliver the laser beam from the laser, a hand piece configured to accept the laser beam from the beam delivery system and direct the laser beam to dental tissue, a sensor configured to detect a treatment parameter as a function of a treatment phenomenon; and a computing device configured to receive the treatment parameter from the sensor; and determine aggregated treated surfaces as a function of the treatment parameter.
US12059314B1
An electric toothbrush connector (100) includes a connector body (10), a pressing module (20) and an elastic member (30). A pressing block groove (101) is disposed in the connector body (10). The pressing module (20) is located in the pressing block groove (101). The clastic member (30) is connected to the connector body (10), and the pressing module (20) is pressed against the pressing block groove (101).
US12059310B2
Improvements for use with tissue expanders are provided. A tissue expander includes: a selectively inflatable and deflatable shell that is configured to be implanted; and an access port for selectively inflating and deflating the shell, the access port comprising a sidewall, a base at a first end, and a membrane at a second end opposite the first end, wherein the sidewall and the base of the access port are constructed of a material that is non-reactive with a magnetic resonance imaging (MRI) machine. In embodiments, the tissue expander includes a magnet at the access port. In embodiments, the magnet is configured with a physical size and magnetic force such that, when the tissue expander is implanted, the magnet is detectable by an external magnetometer sensor but is not detectable by an external dangle-magnet.
US12059309B2
A biosignal measuring apparatus for converting and transmitting biosignals, includes a sensing unit configured to sense a user's electrocardiogram data, a communication unit configured to establish a wireless channel with a data receiving device, and a processing unit configured to determine real-time transmission characteristics based on communication quality information regarding the wireless channel, to determine a data resolution corresponding to the real-time transmission characteristics, to convert the electrocardiogram data according to the data resolution, and to transmit the electrocardiogram data to the data receiving device.
US12059300B2
Described are ultrasound transducer modules and handheld ultrasound imagers including thermal and acoustic management features to produce high quality ultrasound images in a portable, handheld form factor.
US12059296B2
Systems, machine-readable media, and methods for ultrasound imaging can include acquiring three-dimensional data for one or more patient data sets and generating a three-dimensional environment based on one or more transition areas identified between a plurality of volumes of the three-dimensional data. A method can also include generating a set of probe guidance instructions based at least in part on the one or more transition areas and the plurality of volumes of the three-dimensional data, and acquiring, using an ultrasound probe, a first frame of two-dimensional data for a patient. The method can also include executing the set of probe guidance instructions to provide probe feedback for acquiring at least a second frame of two-dimensional data.
US12059295B2
An automated three dimensional mapping and display system for a diagnostic ultrasound system is presented. According to the invention, ultrasound probe position registration is automated, the position of each pixel in the ultrasound image in reference to selected anatomical references is calculated, and specified information is stored on command. The system, during real time ultrasound scanning, enables the ultrasound probe position and orientation to be continuously displayed over a body or body part diagram, thereby facilitating scanning and images interpretation of stored information. The system can then record single or multiple ultrasound free hand two-dimensional (also “2D”) frames in a video sequence (clip) or cine loop wherein multiple 2D frames of one or more video sequences corresponding to a scanned volume can be reconstructed in three-dimensional (also “3D”) volume images corresponding to the scanned region, using known 3D reconstruction algorithms. In later examinations, the exact location and position of the transducer can be recreated along three dimensional or two dimensional axis points enabling known targets to be viewed from an exact, known position.
US12059294B2
Described herein is a wearable device, which comprises an ultrasonic system. The ultrasonic system comprises a substrate that comprises an ultrasonic transducer array and accompanying circuitry. The wearable device is configured to produce useful ultrasonic images.
US12059288B2
Systems and methods are disclosed for assessing the severity of plaque and/or stenotic lesions using contrast distribution predictions and measurements. One method includes: receiving patient-specific images of a patient's vasculature and a measured distribution of a contrast agent delivered through the patient's vasculature; associating the measured distribution of the contrast agent with a patient-specific anatomic model of the patient's vasculature; defining physiological and boundary conditions of a blood flow model of the patient's blood flow and pressure; simulating the distribution of the contrast agent through the patient-specific anatomic model; comparing the measured distribution of the contrast agent and the simulated distribution of the contrast agent through the patient-specific anatomic model to determine whether a similarity condition is satisfied; and updating the defined physiological and boundary conditions and re-simulating distribution of the contrast agent through the one or more points of the patient-specific anatomic model until the similarity condition is satisfied.
US12059280B2
Methods and systems are provided for dynamic collimation adjustment during various x-ray imaging and image-guided procedures. In one example, collimation for an x-ray mammography system is adjusted based on a volume of interest, and further based on a workflow step of an imaging procedure. As an example, prior to a target selection, collimation may be adjusted to irradiate a larger volume of interest and x-ray system acquisition parameters, and hence, a greater area of a detector is irradiated; and after target coordinates are selected (e.g., for an interventional procedure), collimation may be adjusted to irradiate a reduced volume of interest based on the selected target and x-ray system acquisition parameters, and hence, a smaller area of detector is irradiated.
US12059273B2
Provided is an apparatus for estimating bio-information. The apparatus for estimating bio-information according to an embodiment includes a processor configured to obtain a pulse wave signal from a user; extract components of a plurality of element waveforms which constitute a waveform of the pulse wave signal; and obtain a cardiovascular feature based on the extracted components of the plurality of element waveforms. The processor is configured to extract a component of at least one element waveform based on a component of an adjacent element waveform.
US12059271B2
Blood pressure signals are reconstructed from PhotoPlethysmoGraphy (PPG) signals by: receiving PPG signals including systolic, diastolic and dicrotic phases; and determining first and second derivatives of the PPG signals and: a first set of values indicative of lengths of the signal paths of the PPG signal, the first derivative and the second derivative thereof in the systolic, diastolic and dicrotic phases; a second set of values indicative of relative durations of the PPG signal and the first and second derivatives thereof in the systolic, diastolic and dicrotic phases; and a third set of values indicative of the time separation of peaks and/or valleys in subsequent waveforms of the PPG signal. Reconstruction also includes applying artificial neural network processing to the first, second and third set of values. The artificial neural network processing includes artificial neural network training as a function of blood pressure signals to produce reconstructed blood pressure signals.
US12059267B2
Systems and methods for determining the impact of air resistance on the power being produced by a body motion are disclosed. In one aspect, a method includes measuring positions and orientations of a portion of the body in motion. The method further includes measuring pressure experienced by the portion of the body in motion. The motion further includes calculating a static pressure based on the measured pressures and correlated position and orientation measurements. The method further includes calculating a maximum pressure and calculating an air induced power exerted on the body in motion.
US12059265B1
A system for a neurological assessment is provided. The system includes a memory storing instructions for the neurological assessment. The system includes a display, an audio output, a camera, a microphone, and a processor operably coupled thereto. The processor executes the instructions to cause the system to prompt a patient to perform actions, record video and audio of the actions as non-standardized patient specific information via the camera and the microphone, and generate relevant clipped portions from the video and the audio. The relevant clipped portions convert the non-standardized patient specific information into standardized patient specific information. The processor executes the instructions to cause the system to cause a determination of a neurologic status for the patient based on the standardized patient specific information by transmitting the relevant clipped portions to a second system for analysis and receiving an analysis result including the neurologic status from the second system.
US12059249B2
An authentication device includes an image acquisition unit, an identification unit, and an authentication unit. The image acquisition unit acquires an image of an eye of a subject. The identification unit identifies the colored pattern of a colored contact lens worn by the subject by comparing a reference image with the image of the eye. The authentication unit identifies the subject, using a feature in a region other than a colored region of the colored pattern in the iris region of the eye.
US12059239B2
A non-invasive analyte sensor that includes at least one electromagnetic shield at least partially electromagnetically isolates an electrical component of the non-invasive analyte sensor from radio frequency interference and/or microwave frequency interference.
US12059238B2
A wearable monitoring apparatus for monitoring at least one biological parameter of an internal tissue of an ambulatory user. Said wearable monitoring apparatus comprises at least one transducer configured for delivering electromagnetic (EM) radiation to said internal tissue and intercepting a reflection of said EM radiation said reform in a plurality of transmission sessions during at least 24 hours, a processing unit configured for analyzing respective said reflection and identifying a change in said at least one biological parameter accordingly, a reporting unit configured for generating a report according to said change, and a housing for containing said at least one transducer, said reporting unit, and said processing unit, said housing being configured for being disposed on said body of said ambulatory user.
US12059236B2
The blood pressure measurement device includes a bag-like cuff wound around the living body and inflated with a fluid supplied to its internal space, a supply device configured to supply the fluid into the cuff, and guides arranged on the living body side of the cuff and configured to create wrinkles in the cuff on the living body side in a direction intersecting the winding direction of the cuff, when the cuff is inflated to pressurize the living body.
US12059231B2
A dental and facial imaging device includes an adjustable arm, an image sensor mounted on a first end of the adjustable arm and an adjustable patient positioning arm mounted on a second end of the adjustable arm. A distance between the adjustable patient positioning arm and the image sensor is adjustable based on an adjustable length of the adjustable arm. A position indicator scale of the adjustable arm includes multiple notches for calibrating the distance between the adjustable patient positioning arm and the image sensor. The adjustable patient positioning arm includes a patient teeth supporting device and a patient chin rest which are positioned at a fixed coordinate reference relative to the image sensor to capture an image of a patient's teeth. The fixed coordinate reference corresponds to co-ordinates of multiple anatomical planes associated with the patient teeth supporting device and a patient chin rest relative to the image sensor.
US12059227B2
In a method of using a haptic interface for a robot-assisted surgical system, input is received in response to movement of fingers of a human hand. In response to the input, a surgical instrument on a robotic manipulator is moved or actuated. Force input is received from force sensors of the surgical system corresponding to forces against the surgical instrument. In response to the force input, fluid is caused to move into one or more bladders mounted to fingers of the human hand to provide tactile feedback to the user.
US12059222B2
Robotic surgical methods and apparatuses, including systems, for determining positioning information using a combination of AI landmark-identification and visual imaging. Also described herein are methods and apparatuses for determining how to train the AI. Also described herein are end effector devices that may be used with any of the robotic surgical methods and apparatuses. Also described herein designs and techniques incorporating AR into robotic surgical procedures.
US12059213B2
Data characterizing a mother video feed acquired by an endoscopic video capture device can be received. The mother video feed can be for characterizing an operative field within a patient. One or more predefined markers can be identified within the mother video feed. Each of the one or more predefined markers can be associated with a surgical instrument in the operative field. Using the data characterizing the mother video feed, a daughter video feed comprising a sub-portion of the mother video feed can be generated. At least one of a location of the daughter video feed within the mother video feed and a zoom of the daughter video feed can be based on the identified one or more predefined markers. The daughter video feed can be provided. Related apparatus, systems, techniques, and articles are also described.
US12059208B2
A robot-assisted hand-eye coordination training system based on a smooth pursuit eye movement and a guidance force field includes a virtual interactive scene module, a smooth pursuit eye movement detection module, a robot-assisted interception module and an impact force rendering module. The virtual interactive scene module can generate a virtual interactive scene having a virtual moving object and a virtual handle agent. The smooth pursuit eye movement detection module collects an eye movement signal of a user when the user performs pursuit eye movements on the virtual moving object to detect a smooth pursuit eye movement event. The robot-assisted interception module estimates a movement direction of the virtual moving object, generates an interception and guidance force field, and therefore generates assisting force to assist the user in interception. The impact force rendering module generates impact force according to an impact force computation model after collision is detected.
US12059206B2
An ophthalmic stimulator for temporarily constricting a pupil of an eye comprises an irradiation control system, having a feedback system, to generate an irradiation control signal using a feedback of the feedback system; an irradiation source, coupled to the irradiation control system, to generate an irradiation; and an irradiation delivery system, having a targeting system and coupled to the irradiation control system, to receive the irradiation from the irradiation source, and to direct a patterned irradiation in a pattern to a treatment region of an iris of the eye using the targeting system; wherein the irradiation control system controls at least one of the irradiation source and the irradiation delivery system with the irradiation control signal so that the patterned irradiation causes a temporary constriction of the pupil, without causing a permanent constriction of the pupil.
US12059203B2
An electrosurgical instrument for use in minimally invasive surgical techniques that provides a small scale localized microwave field capable of precisely ablating tissue, e.g. in the lungs, through suitable selection of geometry and material for a radiating distal tip thereof. The instrument may be used with a bronchoscope having a power delivery structure formed within the instrument cord thereof. A vision system may be incorporated into the energy delivery structure. The instrument comprise a coaxial cable for conveying microwave energy to a radiating tip portion that comprises a dielectric tip and a distal conductive portion that extends longitudinally therein. The dielectric tip has a dielectric constant greater than a dielectric material within the coaxial cable. The distal end of the device is designed to facilitate efficient microwave energy delivery into lung tumour tissue to achieve a localized volume of ablation.
US12059199B2
The present disclosure relates to a stent delivery system, and can be configured to include a connector portion connected to an external current source, an electrocautery tip connected to the connector portion by a conductive line, and a delivery portion having one side connected to the electrocautery tip, having the other side connected to the connector portion, and having the conductive line for connecting the electrocautery tip and the connector portion positioned therein, and a stent space portion in which a stent is positioned is formed adjacent to the electrocautery tip inside the delivery portion, and the delivery portion gradually moves and supplies the stent into the human body tissue, and according to the present disclosure, it is possible to integrate the conductive line and the tube, thereby improving the rigidity of the tube, and varying the size of the electrocautery tip.
US12059197B2
The present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. Included is a method of treating tissue with electrical energy, the method comprising: delivering electrical energy to tissue using one or more electroporation devices comprising one or more electrodes; and cooling the tissue, surrounding tissue, one or more of the electrodes, or one or more of the electroporation devices to minimize heating. In embodiments, the invention can be used to treat solid tumors, such as brain tumors, and in some embodiments, exemplary methods rely on non-thermal irreversible electroporation (IRE) to cause cell death in treated tumors.
US12059196B2
A surgical instrument includes a housing, a shaft extending distally from the housing, an end effector assembly at a distal end portion of the shaft, and a drive assembly. The drive assembly includes a movable handle, a carriage operably coupled to the movable handle, an inner drive operably coupled to the end effector assembly, and a spring assembly operably coupling the carriage and the inner drive. The spring assembly includes inner and outer coil springs arranged in a nested configuration. Initial actuation of the movable handle slides the carriage such that the spring assembly transfers the sliding of the carriage into translation of the inner drive to apply a jaw force by the end effector assembly. Subsequent actuation of the movable handle slides the carriage to compress the spring assembly to substantially maintain a position of the inner drive, thereby controlling the jaw force.
US12059189B2
Compression/reduction drivers for performing surgical methods are provided. Exemplary surgical methods that may be performed using the compression/reduction drivers described herein include, but are not limited to, arthrodesis procedures (i.e., bone fusion procedures), fracture fixation procedures, etc. The compression/reduction drivers are configured to simultaneously and independently apply a force against a bone segment and drive a fixation device into the bone segment.
US12059185B2
A bone plate can be used to fixate one or more bones. In some examples, the bone plate defines an elongated body having a plurality of fixation holes arrayed at different points along the length of the body. For example, the bone plate may have opposed fixation holes separated by a bridge. The bone plate may be bent or shaped along a central longitudinal axis extending through the elongated body and also twisted around the central longitudinal axis. The bending and twisting can position each fixation hole of the elongated body in a different plane in three-dimensional space.
US12059181B2
A device for a spinal stabilization procedure includes a cannulated tubular body configured to be inserted into a spinal surgical site and an expansion component coupled to the cannulated tubular body. The expansion component can include a plurality of elongated mechanical supports which can be axially aligned with the cannulated tubular body when in a collapsed state, and which can bend outward in a radial direction when in an expanded state. The mechanical expansion can be controlled using one or more adjustment elements of the device. Related apparatus, systems, kits, techniques and articles are also described.
US12059179B2
Expandable spinal fixation assemblies, systems, and methods thereof. An expandable spinal fixation system may include expandable barrel assembly including an upper barrel half and a lower barrel half and a fixed barrel assembly. The fixed barrel assembly is insertable between the upper barrel half and the lower barrel half such that the fixed barrel assembly is clamped between the upper barrel half and the lower barrel half. Each of the expandable barrel assembly and the fixed barrel assembly includes fixation plates adapted to secure spinous processes to the fixation system.
US12059178B2
A percutaneous spinal cross link system for interconnecting a spinal fusion construct on one side of the longitudinal axis of the spine with a spinal fusion construct on the other side of the longitudinal axis may include a cross bar connected at each end by a respective connector to a respective spinal fusion rod of each of the spinal fusion constructs. The connector may include a rod receiving portion adapted to receive one of the spinal fusion rods and a cross bar receiving portion adapted to receive the cross bar in an orientation generally perpendicular to the spinal fusion rod. A cannula defined by two spaced apart blades may be connected to the connector for defining a minimally invasive pathway through body tissue for introduction of the cross bar to the connector. Other tools for use with the system are also disclosed.
US12059174B2
A medical device is disclosed that can help prevent an object existing in a body lumen from clogging a lumen of an elongated member. The medical device including an elongated member having a lumen extending in an axial direction; an insertion member inserted in the lumen of the elongated member on a distal side of the lumen; and a breaking member fixed on an inner surface of the elongated member such that a gap is formed between the insertion member and the breaking member in the lumen of the elongated member on the distal side, and wherein the breaking member exerts a shearing force or a stretching force to the object by rotating relative to the insertion member while the object is between the insertion member and the breaking member.
US12059170B2
A surgical tool that comprises a surgical end effector comprising opposing jaws, an elongate shaft extending distally to the surgical end effector, and a housing defining a passage therethrough, wherein the elongate shaft extends through the passage. The surgical tool further comprises an actuation mechanism configured to selectively move the housing along the elongate shaft relative to the surgical end effector. The actuation mechanism comprises a pulley, a cable engaged with the pulley, and a lock arrangement configured to releasably lock the housing relative to the elongate shaft. The lock arrangement comprises a washer positioned around the elongate shaft. The cable is engaged with the washer. An actuation of the pulley is configured to apply a tension to the cable to pivot the washer relative to the elongate shaft from a locked orientation to an unlocked orientation.
US12059161B2
A clot removal system comprises a catheter, a vacuum source, and a controller. The catheter comprises a proximal end, a distal end, and controller operating parameters and defines a lumen configured to be filled with a liquid column having a proximal portion. The vacuum source is configured to supply vacuum. The controller is configured to carry out a control pattern of turning on and off the vacuum based upon the controller operating parameters and is configured to receive the controller operating parameters in an automatic response to the catheter being operatively connected to at least one of the vacuum source and the controller and, responsive to the connection, to carry out the control pattern to change a level of vacuum at the distal end of the catheter.
US12059156B2
An apparatus is provided for treating a vascular malformation. The apparatus includes an orifice section, an intra-vascular-malformation docking section, and a connecting section. The apparatus is configured such that, when unconstrained the orifice section is shaped so as to define an orifice-section curve that winds at least 2.5 turns around an orifice-section central axis at a changing distance from the orifice-section central axis, the intra-vascular-malformation docking section is shaped so as to define a docking-section curve that winds between 0.5 and 2 turns around a docking-section central axis at a changing or constant distance from the docking-section central axis, and the connecting section connects the orifice-section curve with the docking-section curve, and has an average radius of curvature that is different from an average radius of curvature of an outermost loop of the orifice-section curve. Other embodiments are also described.
US12059153B2
A compressible adjunct kit for use with a staple cartridge is provided and includes a biocompatible adjunct material and a pretreatment fluid. The biocompatible adjunct material is configured to be releasably retained on a staple cartridge and is configured to be delivered to tissue by deployment of staples in the staple cartridge. The adjunct material can be in the form of a porous polymer body. The pretreatment fluid is configured to be applied to the adjunct material to change the adjunct material from an untreated state to a treated state. The adjunct material in the untreated state is configured to exhibit a first degradation profile when delivered to tissue. The adjunct material in the treated state is configured to exhibit a second degradation profile, different from the first degradation profile, when delivered to tissue.
US12059152B2
In some embodiments, torque compensation in a clamping instrument includes control electronics obtaining an initial torque limit for the clamping instrument, adjusting the initial torque limit based on a temperature of a motor assembly used to operate the clamping instrument, and clamping the clamping instrument according to the adjusted torque limit. The adjusted torque limit corresponds to a maximum torque that may be applied by the clamping instrument to perform the clamping. In some embodiments, torque compensation in a stapling instrument includes control electronics obtaining an initial torque limit for the stapling instrument, adjusting the initial torque limit based on a number of times the stapling instrument has been fired, and firing the stapling instrument according to the adjusted torque limit. The adjusted torque limit corresponds to a maximum torque that may be applied by the stapling instrument to perform the firing.
US12059146B2
A toggle-type suture anchor that incorporates individual suture tensioning and locking without knot tying. The anchor includes an elongate toggle body having a working suture pre-threaded into a first passage and back up and out a second passage with a length running longitudinally adjacent the side of the anchor. A locking suture loop is pre-threaded into a third passage between the first and second passage and includes a collapsible loop that encircles a portion of the length of suture running longitudinally adjacent the side of the anchor. With the loop open, the working suture can slide through the anchor, however, when the loop is closed the working suture is locked in position to retain tension on the working suture. The anchor can be utilized in a pre-strung connected array of anchors.
US12059144B2
A delicate tissue retraction system for use with a navigation probe having a probe shaft and a probe tip at a distal end of the probe shaft. The delicate tissue retraction system includes a retractor and an introducer that is removably installed within the retractor. The introducer has a wall forming a hollow channel extending from a proximal introducer end to a distal introducer end. A mount is integrally formed with the introducer and extends from the distal introducer end into the channel. The mount is positioned to surround the probe tip when the navigation probe is at a fully inserted position within the introducer with the probe tip at the distal introducer end.
US12059131B2
The present invention provides a robotic locomotive device (1) that is capable of driving itself forwards and backwards, anchoring and steering itself whilst inside a tubular structure (200), for example, the human colon, or any structure comprising two opposing walls (202, 204). In this respect, the device is made up of two or three segments (102, 104, 106) covered in an elastic material and driven by an internal actuating mechanism. All of the segments (102, 104, 106) have a concertina configuration that enable a shortening and lengthening motion. As well as contracting and extending in length, at least one of the end segments (102, 106) is capable of bending at an angle away from the longitudinal axis such that it becomes wedged or jammed between the walls (202, 204) of the tubular structure (200). That is, the end segments (102, 106) are capable of both a bending action and a contracting and extending action. The device (1) moves by alternately jamming a segment (102, 104, 106) between the walls (202, 204) of the tubular structure (200), and then contracting or extending the segments (102, 104, 106) to inch the device (1) forward with a more effective locomotive action. As such, the present invention provides a simplified design that is more robust to harsh or unclean environments, whilst still maintaining the level of performance required from such a device.
US12059128B2
A device for distending a body lumen for enhanced visualization with a capsule endoscope includes a plurality of struts configured to extend from the capsule endoscope, a retention mechanism configured to attach the plurality of struts to the capsule endoscope, and a trigger configured to release the retention mechanism.
US12059123B2
The present invention aims to provide a medical image processing apparatus, a medical image processing method, a program, and an endoscope system that report a region of interest without interrupting observation of a medical image. The above problem is solved by a medical image processing apparatus including: an emphasis processing unit that emphasizes a position of a region of interest included in a plurality of medical images sequentially displayed on a display unit; and a transition time setting unit that sets a transition time in accordance with a feature quantity of the region of interest, in which the emphasis processing unit emphasizes the position of the region of interest at a first emphasis level and, after the transition time has elapsed from emphasis at the first emphasis level, emphasizes the position of the region of interest at a second emphasis level relatively lower than the first emphasis level.
US12059116B2
A bypass valve may include a body defining a dirty air passageway, a nozzle coupling port configured to fluidly couple the dirty air passageway to a nozzle of the surface cleaning device, a wand coupling port configured to fluidly couple the dirty air passageway to a wand of the surface cleaning device, a suction coupling port configured to fluidly couple the dirty air passageway with a suction motor of the surface cleaning device, a wand receptacle configured to removably couple to the wand, and a valve bypass arrangement configured to selectively redirect air flowing through the body such that a majority of the air flowing through the body transitions between flowing through one of the wand coupling port and the nozzle coupling port. The valve bypass arrangement redirects the air in response to the wand being coupled to or decoupled from the wand receptacle.
US12059115B2
A self-driving cleaner includes a main body and a driving unit for driving in a cleaning area. The cleaner suctions foreign material on the floor in the cleaning area. The cleaner includes a first pattern irradiation unit and a second pattern irradiation unit on the front surface of the main body, the first and second pattern irradiation units radiating light in a preset pattern towards the front lower side and the front upper side of the main body, respectively. The cleaner includes a camera on the front surface of the main body, for capturing, at a preset interval, an image including a first light pattern and a second light pattern formed by the first and the second pattern irradiation units, respectively. The cleaner includes a control unit for determining whether a first obstacle exists at a location upwardly spaced apart from the floor, using the image captured by the camera.
US12059111B2
Disclosed are a cleaning roller and a rolling steam mop. The cleaning roller includes a central shaft capable of rotating, a steam channel, and a cleaning layer. The steam channel is provided with a steam inlet and a plurality of first steam outlets; the steam inlet is used for communicating with a steam generation device: the plurality of first steam outlets are distributed in an axial direction of the central shaft. The cleaning layer is provided around the central shaft; and the steam flowing out from the first steam outlets can be diffused outwards through the cleaning layer When in use, the steam generated by the steam generation device enters the steam channel through the steam inlet, and then flows out from the first steam outlets, and is diffused outwards through the cleaning layer, so that the steam can be diffused to an object to be cleaned.
US12059093B2
The invention relates to beverage extraction unit (1) for extracting a beverage from an exchangeable capsule (2) containing beverage ingredients and being configured for operating according to two beverage extraction modes, e.g. at respectively high pressure or low pressure. The invention also relates to the beverage machine comprising the extraction unit.
US12059087B2
Flexible element for forming a piece of disposable cutlery, especially a spoon, including an elongated body made from thin, bendable material including a handle and acting portions, each with a free end. A first bending line on the body extends longitudinally from the handle portion free end towards the acting portion, so the body may be bent longitudinally and in the bent position, the working position, the handle portion is V-shaped or U-shaped. The body has an elongated opening including at one side a lip, pointing from the handle portion free end towards the acting portion. A fifth bending line extends transverse to the first bending line, visually dividing the body into the handling and acting portions. The fifth bending line is positioned so when the body is folded along such, a part of the acting portion free end can be inserted into the opening, behind the lip.
US12059086B2
A cake shield with a top cover and side wall dimensioned to enclose a cake to prevent contamination during celebration is disclosed. Recesses in the top cover may include a recessed track dimensioned to hold multiple candles, a deeper cylindrical or conical recess, or a recess dimensioned for a candle with a rectangular footprint. Use of transparent material allows the cake to be viewed under the shield. The cake shield may comprise a base wall that supports the side wall of the top cover, and two or more pieces may interlock to form the base wall. A kit may also include a base plate for supporting both the cake and the side wall, as well as decorations for the top cover that may include candles and other materials.
US12059083B2
A refrigerator has an open front, an air curtain system having at least one upper air egress having an outer edge and at least one lower air-recovery ingress. The air curtain system is adapted to produce a substantially vertical air curtain over at least part of the open front of the refrigerator. The refrigerator has a plurality of shelves between the egress and the ingress a plurality of shelves between the egress and the ingress including a first shelf that has an aerofoil positioned in front of it, the first shelf being located in the upper half of the open front of refrigerator. The refrigerator also includes a second shelf that does not have an aerofoil positioned in front of it, the second shelf being located below the first shelf.
US12059065B2
A mixing machine, configured to receive a receiving device in order to form a mixing machine includes a support defining a receiving housing, able to receive a receiving device, the receiving device being configured to receive first and second capsules containing respectively a first formulation and a second formulation, the two capsules being fluidly linked to each other, an actuation system, movable inside the receiving housing to exert a pressure force on the receiving device and/or on the first and/or the second capsule(s), and a coupling mechanism, movable relative to the support and configured: in an insertion position, not to interfere with the insertion and the withdrawal of the receiving device into/from the receiving housing, and in a coupling position, to exert a force on an actuation face of the receiving device.
US12059059B2
A sports footwear assembly for providing a removable bracket for a shoe to which cleats are removably attached includes a shoe with a rubber sole and a bracket for attaching to the sole which is rigid. A plurality of holders is coupled to the bracket, each of which is shaped to contain a plurality of cleats. Each cleat is removably coupled to one of the holders and extends downwardly to insert into a ground surface.
US12059057B2
An article of footwear includes a sole structure, an upper, and a securing mechanism. The upper comprises a toe region, a midfoot region, a heel region, a lateral side, and a medial side, and is coupled to the sole structure. The securing mechanism is fixedly attached to the upper and comprises a forefoot portion and a heel lock element. The heel lock element has a first and a second end and extends from the lateral side of the upper, passes around the heel region of the upper, and extends to the medial side of the upper. The heel lock element comprises a stiffness that is greater than the stiffness of the upper and is configured such that tensioning the securing band adjusts the heel segment of the main portion relative to a wearer's heel.
US12059051B2
The invention relates to a protective sports helmet purposely designed for a selected group of helmet wearers from amongst a larger population of helmet wearers. A multi-step method for helmet design starts by collecting information from a population of players that may include information about the shape of a player's head and the impacts the player has sustained. This information is then processed to create player population information that is sorted to create categories. Advanced mathematical techniques are utilized to further sort these categories into player groups or data sets based on player attributes. Once the player groups are identified, another multi-step process is utilized to design optimized helmet prototype models for each player group. These optimized helmet prototype models are then further processed into complete helmet models by determining a structural design and chemical composition that is manufacturable and has mechanical properties that are substantially similar to the optimized helmet prototype model. Physical helmet prototypes are then created and tested using a unique helmet standard derived from information associated with each player group. Once the prototypes pass testing, the complete helmet models can be manufactured to create actual stock helmets or stock helmet components for future players whose characteristics and attributes place them within the selected player group.
US12059040B2
An electrically operated aerosol generating system may include a storage portion configured to store an aerosol forming substrate, at least one heating element configured to heat the aerosol forming substrate, a sensor configured to detect an activation of the system, a clock, and electric circuitry connected to the sensor. A usage parameter associated with operation of the system may be measured and compared, to a threshold value. A usage profile of the system may be determined based on the comparison. Such operations may be repeated at different times of day. An operating mode of the system may be selectively executed based on the determined usage profile associated with the current time of day. A monitoring procedure may be ended when the measured usage parameter exceeds a threshold value, and the duration of the monitoring procedure may be compared to a threshold duration to determine the usage profile.
US12059036B2
The present is disclosure relates to a power supply component of an electronic atomization device. The power supply component includes an outer housing, a fixing holder, and an airflow trigger. The outer housing is provided with a collecting cavity. The fixing holder is installed on the bottom of collecting cavity. The bottom of the fixing holder is provided with an accommodating cavity. The airflow trigger locates at the open end of the accommodating cavity and forms a closed space with the accommodating cavity. The power supply component further includes an air column with one end closed. The open end of the air column communicates with the enclosed space. The side wall of the air column is provided with an air port in the collecting cavity to make the closed space and the collecting cavity connected.
US12059024B2
There is provided an aerosol-generating article (10) comprising an aerosol-generating substrate (12) and a filter (14) in axial alignment with the aerosol-generating substrate (12). The filter (14) comprises at least one segment of filtration material formed of one or more sheets of a fibrous paper-like material. The fibrous paper-like material comprises a combination of hydrophobic fibres and hydrophilic fibres such that the fibrous paper-like material has a water contact angle as measured in accordance with TAPPI/ANSI T 558 om-15 greater than 90 degrees. Further, the fibrous paper material has a biodegradability in aqueous medium as tested in accordance with ISO 14851 (2005) of at least 90 percent of the maximum degradation of a cellulose reference item within 56 days of testing. In addition, the hydrophobic fibres comprise hydrophobic viscose fibres.
US12059018B2
The invention concerns an apparatus (10) for roasting coffee beans comprising:—a housing (4),—a roasting chamber (1) presenting a bottom opening (11),—an air driver (2) configured to drive air inside the roasting chamber through the bottom opening of said chamber,—an electrical heater (3) positioned below the bottom opening of the roasting chamber, said electrical heater being configured to heat air driven inside the roasting chamber,—the air driver and the electrical heater being positioned inside the housing (4) and the housing comprising a hot air outlet hole (41) designed to enable the passage of hot air from the housing inside the bottom opening (11) of the roasting chamber, and the electrical heater (3) being positioned just below the hot air outlet hole (41),—the roasting chamber (1) being removably mounted to the housing (4), the bottom opening (11) of the roasting chamber cooperating with the hot air outlet hole (41) of the housing when the roasting chamber is mounted to the housing, wherein the apparatus comprises a movable closure device (5) configured:—to cover the hot air outlet hole (41) while the roasting chamber is being removed from the housing, and - to uncover the hot air outlet hole (41) while the roasting chamber is being mounted to the housing.
US12059017B2
The present invention “Production process of nixtamalized maize flour, nixtamalizing the maize fractions separately without producing nejayote”, considers the integration of the processes: Semi-humid milling of the maize (fractionated degerm), extruding of the maize endosperm and milling-instant dehydration of the different nixtamalized and extruded maize fractions, has as novelty the way in which the nixtamalization process is carried out and the objective is to provide a nixtamalized maize flour production system that reduces the residues from the maize grain and completely eliminating nejayote production.
US12059010B2
The present invention relates to a maple syrup product having a low water content. The maple syrup product retains the physical and palatable properties of untreated maple syrup while having a prolonged shelf-life. It can be advantageously used to sweeten beverages (such as hot beverages) and in the manufacture of pharmaceutical compositions (such as throat lozenges) and/or confectionery.
US12059009B2
The invention relates to a conveyor system for moulds (12) of an industrial confectionery machine (2), which comprises a plurality of production stations (P1, P2, P3, P4, 3, 4, 5, 6, 7) and moulds (12) for producing at least one confectionery article, wherein with the confectionery machine (2), a mould (12) can be conveyed to the various production stations (P1, P2, P3, P4, 3, 4, 6,, 7) for successive production steps, comprising a conveyor rail (8, 8a, 8b, 72, 73, 74, 75, 76, 77, 79, 80, 81, 82) and a drive device (9, T1, 67, D1, D2, D3, G1, G2, G3), with which a conveyance movement for a mould (12) can be produced in order to convey the mould (12) along the conveyor rail (8, 8a, 8b, 72, 73, 74, 75, 76, 77, 79, 80, 81, 82) to the production stations (P1, P2, P3, P4, 3, 4, 5, 6, 7).
US12059006B2
Compositions of microalgae-derived flour are disclosed from multiple genera, species, and strains of edible microalgae. Microalgae used in the invention are free of algal toxins and contain varying levels of primarily monounsaturated triglyceride oil. Flours disclosed herein are formulated as free flowing blendable powders, mixed food ingredients, oxidation stabilized, homogenized and micronized, and combinations therein. Flours disclosed herein also form self stabilizing emulsions in slurries with manageable viscosities. Innovative methods of formulating flours and incorporating them into food compositions are also disclosed. The invention also comprises flours with significant digestible protein and unique dietary fiber content and associated water binding, texturizing, and healthy oil delivery attributes. Novel methods of oil and fat replacement using flours of the invention are also disclosed. Flours of the invention can be manufactured from edible and inedible heterotrophic fermentation feedstocks, including corn starch, sugar cane, glycerol, and depolymerized cellulose.
US12058998B1
The present invention provides a permeable and options for semi-permeable inevitable substrate and substance made from minerals, vitamins, and detox formulas and is derived from the manufacturing process of the present invention. In one embodiment, the permeable inevitable substrate and substance may be used in clothing or other articles to be worn, in hospital settings, areas of nuclear waste, areas high in toxins, or areas of high radiation that may enable the radiation, the high energy levels and the toxins to activate the substrates and formulas that have been infused into clothing to self-clean and detox the clothing while it is being worn. In another embodiment, semi-permeable methods may be used by utilizing various forms of silicas and ortho silicates to ensure that positive molecules and ions are able to be diffused, while keeping out negative ions and minerals by diffusion or breaking apart the negative compositions.
US12058969B2
The present invention provides novel lettuce cultivar Cardinal and plant parts, seed, and tissue culture therefrom. The invention also provides methods for producing a lettuce plant by crossing the lettuce plants of the invention with themselves or another lettuce plant. The invention also provides lettuce plants produced from such a crossing as well as plant parts, seed, and tissue culture therefrom.
US12058968B2
Nucleic acid and polypeptide sequences for predicting and controlling shell phenotype in palm.
US12058965B1
A plant cover device comprises an enclosure having mesh material to define a plant-receiving cavity. The enclosure includes a first mesh section having a closed top end, and a first perimeter opposite the closed top end, and a second mesh section having a second perimeter attached to the first perimeter of the first mesh section, and a bottom end opposite the closed top end of the first mesh section defining a trunk receiving opening. The plant cover device also includes a support extending vertically from a ground surface through the first and second perimeters and to abut the closed top end of the enclosure.
US12058962B2
A lockout device for a round baler. The lockout device has a body configured for being connected to a side of the tailgate of the round baler, a handle pivotally connected to the body at a pivot point, a wedge pivotally connected to the body at the same pivot point, and a biasing member connected in between the handle and the wedge. The handle is configured for pivoting in between a closed position and an open position for pivoting the wedge to be at least partially within the bale chamber to lock out the bale chamber.
US12058960B2
A walk-behind self-propelled machine includes: a body, wheels, a handle connected to the body, a motor, a driver coupled to the motor and driven by the motor, and a follower coupled to the wheels and enabled to drive the wheels to rotate, and a clutch. The clutch allows the driver to transmit power to the follower when the clutch is in a first position, the clutch cuts off a power transmission path between the motor and the wheels when the clutch is in a second position, the clutch is rotatably mounted to the driver, the clutch is in contact with the follower when the clutch rotates to the first position, and the clutch is disengaged from the follower when the clutch rotates to the second position.
US12058959B2
A reel assembly of an agricultural header includes a first arm configured to support a reel of the reel assembly and a first pivot joint configured to pivotally couple the first arm to a frame of the agricultural header. The first pivot joint is configured to enable the first arm to pivot about a first local lateral axis of the agricultural header and about a longitudinal axis of the agricultural header relative to the frame. In addition, the reel assembly includes a second arm configured to support the reel and a second pivot joint configured to pivotally couple the second arm to the frame. The second pivot joint is configured to enable the second arm to pivot about a second local lateral axis of the agricultural header relative to the frame and to substantially block pivoting of the second arm about the longitudinal axis relative to the frame.
