The invention discloses a thermocouple compensation cable for an aircraft engine, which is formed by combining at least two types of wires. Each type of wires comprises a plurality of strands; all the wires are coated in the same pure nickel wire woven total shielding layer; a FEP (Fluorinated Ethylene Propylene) protection layer is also coated outside the pure nickel wire woven total shielding layer; one type of wires is formed by sequentially coating a synthetic mica and calcia-alumina-silica fiber woven layer, a high temperature resistance coating and a pure nickel wire woven branch shielding layer outside a nickel-chromium anode conductor. The invention provides the high temperature resistance and high reliability thermocouple compensation cable for the aircraft engine, solves the problem that in the prior art, the characteristics of high performance, light weight, high reliability, high temperature resistance and the like cannot be simultaneously implemented, and solves the problem of mutual restriction among the cable high temperature resistance requirement, the cable outer diameter setting, the working voltage requirement and the transmission requirement by the material selection and the structure design of the cable.