中科微点-全球专利检索

  1. Login
  2. Sign Up
Invention Publication
CN106511299A 一种核壳结构的四氧化三铁/金/二氧化硅纳米粒子的制备及用近红外光控制药物释放 有权 转让

  • Patent Title: 一种核壳结构的四氧化三铁/金/二氧化硅纳米粒子的制备及用近红外光控制药物释放
  • Patent Title (English): Preparation of ferriferrous oxide/gold/silicon dioxide nanoparticles of core-shell structure and drug release controlled through near-infrared light
  • Application No.: CN201610911532.X
    Application Date: 2016-10-19
  • Publication No.: CN106511299A
    Publication Date: 2017-03-22
  • Inventor: 孔泳 , 刘晓霖
  • Applicant: 常州大学
  • Applicant Address: 江苏省常州市武进区滆湖路1号
  • Assignee: 常州大学
  • Current Assignee: 西安湄南生物科技股份有限公司
  • Current Assignee Address: 712000 陕西省咸阳市西咸新区空港新城敦化路鸿升行航空科技产业园南一区5号厂房
  • Main IPC: A61K9/51
  • IPC: A61K9/51 ;  A61K31/7048 ;  A61K47/04 ;  A61K47/02 ;  A61K41/00 ;  A61P35/00 ;  A61P35/02
一种核壳结构的四氧化三铁/金/二氧化硅纳米粒子的制备及用近红外光控制药物释放
Abstract:
本发明涉及一种核壳结构的四氧化三铁/金/二氧化硅纳米粒子的制备及用近红外光控制药物释放。包括以下步骤：制备四氧化三铁纳米粒子,四氧化三铁/金纳米粒子,四氧化三铁/金/二氧化硅纳米粒子，将药物负载到复合材料上，用近红外光照射控制体外药物释放。本发明的有益效果是：四氧化三铁/金/二氧化硅纳米粒子具有优良的生物降解性，且可以在外加磁场的作用下靶向定位病变组织，在近红外光照射下将光转化成热控制药物缓慢释放，使药物在体内缓慢释放并有效利用。
Abstract(English):

The invention relates to preparation of ferriferrous oxide/gold/silicon dioxide nanoparticles of a core-shell structure and drug release controlled through near-infrared light. A preparation method includes the following steps that ferriferrous oxide nanoparticles, ferriferrous oxide/gold nanoparticles, ferriferrous oxide/gold/silicon dioxide nanoparticles are prepared, a chemical is loaded on a composite material, and in-vitro drug release is controlled through irradiation of the near-infrared light. The ferriferrous oxide/gold/silicon dioxide nanoparticles have good biodegradability, can target and position pathological tissue under the action of an external magnetic field and convert light into heat under irradiation of the near-infrared light to control drug slow release, so that drugs are released slowly in bodies and effectively used.

Public/Granted literature
Patent Agency Ranking
0/0