A photoelectric mixed vertical watertight connector comprises a plug and a socket. The plug comprises a casing, an optical insertion core, an electric insertion core, a tail cover, a bonding seat, a connecting rod and a single-strand lead, the bonding seat is mounted in the left end of the connecting rod, the bonding seat and the connecting rod are installed in an inner cavity of the casing, a first sealing device is mounted between the bonding seat and the casing, an inner cavity of the bonding seat is filled with epoxy glue and vulcanizate, the vulcanizate is positioned on the right of the epoxy glue, a wire isolating plate is arranged in the right portion of the inner cavity of the bonding seat, and positioned within the epoxy glue, the single-strand lead and a fiber are connected with the optical insertion core and the electric insertion core after penetrating the wire isolating plate respectively, the tail cover is mounted in the left end of the casing, the optical insertion core and the electric insertion core are mounted in the right end of the connecting rod, the left end of the single-strand lead is positioned in the epoxy glue and is electrically connected with a multi-strand lead in a photoelectric composite cable, the right end of the single-strand lead is electrically connected with the electric insertion core, and an optical fiber in the photoelectric composite cable penetrates the epoxy glue and is then in signal connection with the optical insertion core. The photoelectric mixed vertical watertight connector is lower in manufacture cost and reliable in vertical sealing, and can ensure safe operation of an electron cabin.