The invention discloses a high-efficiency and non-doped white organic light-emitting diode and a fabrication method thereof. The device structure comprises a substrate, a positive electrode layer, an organic functional layer and a negative electrode layer, wherein the organic functional layer comprises a hole injection layer, a hole transmission layer, a light-emitting layer and an electron transmission layer, and the light-emitting layer comprises one of the two modes: 1, a yellow fluorescent light-emitting material layer (the thickness is 1-10 nanometers) which is near to the hole transmission layer and has thermally activated delayed fluorescence characteristic and a conventional blue fluorescent light-emitting material layer near to the electron transmission layer; and 2, a conventional blue fluorescent light-emitting material layer near to the hole transmission layer and a yellow fluorescent light-emitting material layer which is near to the electron transmission layer and has thermally activated delayed fluorescence characteristic. The white device is achieved only by employing the blue fluorescent light-emitting material and a simple device structure, meanwhile, the device efficiency can be improved, the efficiency roll-off is reduced, and the production cost is reduced.