The invention discloses a unilateral core-winding clamping type brush sealing structure. The unilateral core-winding clamping type brush sealing structure comprises a front baffle plate, a C type clamp, a rear baffle plate, a core wire, a front end decompression plate, a rear end decompression plate and a brush wire, wherein the C type clamp is clamped and fixed between the front baffle plate andthe rear baffle plate, the front end decompression plate and the rear end decompression plate are connected to the lower ends of the front baffle plate and the rear baffle plate correspondingly, and the front end decompression plate and the rear end decompression plate raise inwards correspondingly to form a decompression chamber. The lower end of the C type clamp is connected with a vertical baffle plate, and the brush wire is wound on the core wire and arranged in a clamping hole of the C type clamp in a tightly clamped mode. In the initial mounting state, the free end of the brush wire is attached to the inner side of the vertical baffle plate and the inner side of the rear end decompression plate sequentially, and extends out of the decompression chamber and in contact with a rotor. The unilateral core-winding clamping type brush sealing structure is low in production cost, the material of the brush wire can select a metal or non-metal material, the brush wire is replaceable and simple to mount, the hysteresis effect is reduced greatly, the property of the brush wire is stable and reliable, the service life of the brush wire is long, and the brush sealing structure can be widely applied to various kinds of turbine mechanical equipment.