The invention discloses a method for optimized wake-up strategy, and a computer readable medium and system. The method comprises receiving a set of raw sensory data of a user's sleeping status; translating the set of raw sensory data into a plurality of sleeping stages; saving the plurality of sleeping stages as a history of sleeping stages; determining a current sleeping stage; predicting a plurality of future sleeping stages of the user in an upcoming interval; calculating a wakeup score of the current sleeping stage and a wakeup score of each future sleeping stage; determining an optimizedsleeping stage for wake up based on the wakeup score through comparing the wakeup score of the current sleeping stage and the wakeup scores of the future sleeping stages; and triggering an alarm impulse to wake up the user at the optimized sleeping stage for wake up.