Te invention provides a manufacturing method of a flexible display panel. A sacrificial layer is arranged between a rigid bearing plate and a flexible substrate of the flexible display panel; the sacrificial layer comprises a first sacrificial layer and a second sacrificial layer positioned on the periphery of the first sacrificial layer and tightly connected therewith; by virtue of setting of thesacrificial layer, direct contact between laser and the flexible substrate in a laser lift-off process can be reduced or avoided, so that the probability of damage to the flexible substrate is lowered; and in addition, by virtue of setting of the second sacrificial layer on the periphery of the first sacrificial layer, transverse transmission of heat can be accelerated, and longitudinal transmission of heat can be reduced, so that damage to an TFT layer and an OLED luminous layer by the heat generated in the laser lift-off process can be avoided, and the production yield of the flexible display panel can be improved.