The invention discloses aspergillus niger BFA010-7 which is obtained through soil screening and low-temperature plasma mutagenesis and is capable of achieving high yield of D-pantolactone, and an application of the aspergillus niger strain BFA010-7 in preparing the D-pantolactone, wherein the preservation number of the aspergillus niger strain BFA010-7 is CGMCC 14631. According to the invention, aspergillus niger mycelia achieve growth and propagation in a sponge block in an embedding mode, and then an immobilized cell catalyst is prepared through a chemical cross-linking method; and the entire process is simple and easy to implement, cheap and practicable and easy for amplification; and the prepared immobilized cell catalyst has the advantages of being high in activity, good in operatingstability, easy for separation and recovery and the like, and the immobilized cell catalyst has a good application prospect in an industrial production process of D-calcium pantothenate.