The invention discloses a pipeline AC interference protection drainage system, which belongs to the technical field of petroleum pipelines. The drainage system comprises a drainage device and a drainage bed, wherein the drainage bed is electrically connected with the pipeline through the drainage device; the drainage bed comprises a well body, a pre-packed anode assembly, a casing and backfilled soil in the well; the pre-packed anode assembly is arranged in the well body; the pre-packed anode assembly comprises an outer protective pipe, a conductive filler, an underground cable, a preset protection pipe and multiple anodes; the preset protection pipe is arranged in the outer protective pipe; the top end of the preset protection pipe is communicated with the bottom end of the casing; the top end of the casing extends out of the well body; the underground cable is arranged in the preset protection pipe; a drainage gap is arranged between the underground cable and the preset protection pipe; the top end of the underground cable passes through the casing and is electrically connected with the grounding electrode end of the drainage device; each anode is electrically connected with theunderground cable; and the pipeline end of the drainage device is used for being electrically connected with the pipeline. Generation of gas lock effects is avoided.