The invention discloses a radiation photovoltaic isotope battery packing structure. The radiation photovoltaic isotope battery packing structure consists of components including a metal packing shell,a photovoltaic transduction device, a radiation luminescent device, a circuit board, a compression spring and the like. A metal packing lower shell comprises a sealing electrode formed by sintering of glass, an insulating electrode is connected with a circuit on a lower circuit board, a photoelectric transduction device and a spring ejector pin are welded to the lower circuit board, and the lowercircuit board and the metal packing lower shell are sintered integrally; a photoelectric transduction device is welded to the middle of an upper circuit board, a pressure connection table edge is arranged at an edge of the upper circuit board, and the upper circuit board is in pressure connection with the spring ejector pin on the lower circuit board through a contact on the upper circuit board so that the upper circuit board and the lower circuit board are electrically connected with each other; and according to the radiation photovoltaic isotope battery packing structure, battery modules are designed in a modularized manner, and preparations such as compression, welding and electric mutual connection can be realized in a box chamber by simple assembly.